Genotypic Resistance Tests Sequences Reveal the Role of Marginalized Populations in HIV-1 Transmission in Switzerland.

Targeting hard-to-reach/marginalized populations is essential for preventing HIV-transmission. A unique opportunity to identify such populations in Switzerland is provided by a database of all genotypic-resistance-tests from Switzerland, including both sequences from the Swiss HIV Cohort Study (SHCS) and non-cohort sequences. A phylogenetic tree was built using 11,127 SHCS and 2,875 Swiss non-SHCS sequences. Demographics were imputed for non-SHCS patients using a phylogenetic proximity approach. Factors associated with non-cohort outbreaks were determined using logistic regression. Non-B subtype (univariable odds-ratio (OR): 1.9; 95% confidence interval (CI): 1.8-2.1), female gender (OR: 1.6; 95% CI: 1.4-1.7), black ethnicity (OR: 1.9; 95% CI: 1.7-2.1) and heterosexual transmission group (OR:1.8; 95% CI: 1.6-2.0), were all associated with underrepresentation in the SHCS. We found 344 purely non-SHCS transmission clusters, however, these outbreaks were small (median 2, maximum 7 patients) with a strong overlap with the SHCS'. 65% of non-SHCS sequences were part of clusters composed of >= 50% SHCS sequences. Our data suggests that marginalized-populations are underrepresented in the SHCS. However, the limited size of outbreaks among non-SHCS patients in-care implies that no major HIV outbreak in Switzerland was missed by the SHCS surveillance. This study demonstrates the potential of sequence data to assess and extend the scope of infectious-disease surveillance.

Estrutura societária e controle minoritário no Brasil Telecom: análise do poder exercido pelo Opportunity de 2003 a 2005

Desde meados dos anos 1990 o ambiente de negócios brasileiro tem passado por um relevante incremento na sofisticação da modelagem de estruturas societárias para grandes empreendimentos, um tipo de conhecimento que, porém, fica na maior parte restrito aos participantes desses empreendimentos e seus assessores jurídicos e financeiros. No caso da estruturação societária da Brasil Telecom, entretanto, foi possível ter acesso a todos os documentos e informações necessários ao estudo dessa estrutura, devido à enorme quantidade de litígios judiciais em que essa companhia esteve envolvida por quase dez anos, nos quais se pode obter a maior parte dos documentos analisados neste trabalho. Esse material é precioso, pois o caso da Brasil Telecom, conhecido como um dos maiores do direito societário brasileiro, tem uma peculiaridade muito importante: o grupo era gerido por um acionista minoritário, o grupo Opportunity, que exerceu poder de controle durante esses dez anos, apesar de sua diminuta participação societária e da forte oposição que sofreu dos acionistas majoritários por quase todo o tempo em que exerceu esse poder. O objetivo desse trabalho é revelar as técnicas jurídicas que permitiram o exercício desse poder, bem como buscar entender por que, apesar de tanta oposição dos demais acionistas e da enorme litigiosidade, anos transcorreram até que o Opportunity fosse definitivamente afastado da administração e do exercício do poder de controle da Brasil Telecom.

Post-H1N1 Flu Vaccination Narcolepsy in Switzerland: A Retrospective Survey in the 30 Sleep-Certified Swiss Centers

Narcolepsy-cataplexy is a sleep-wake disorder and suggested to be immune-mediated, involving genetic and environmental factors. The autoimmune process eventually leads to a loss of hypocretin neurons in the lateral hypothalamus. Epidemiological studies in several countries proved an increased incidence of narcolepsy after H1N1 flu vaccination and infection. This survey in 30 sleep centers in Switzerland led to the identification of 9 H1N1-vaccinated children and adults as newly diagnosed narcolepsy. Clinical features included the abrupt and severe onset of sleepiness, cataplexy and sleep fragmentation.

Toward equal educational opportunity : affirmative admissions programs at law and medical schools.

Includes bibliographical references.

Actas de la primera conferencia de la Office of Economic Opportunity sobre Programas Contra la Pobreza para Trabajadores Migratorios y Trabajadores de Periodos Temporales Durante el año Agrícola efectuadas el 18 al 20 de enero de 1966 en Washington, D. C.

Mode of access: Internet.

The Mexican American : a new focus on opportunity /

"A report on the activities of the Inter-agency Committee on Mexican American Affairs for the year ending June 30, 1968"--p. [1].

Proceedings of the first Office of Economic Opportunity Conference on Antipoverty Programs for Migrant and Seasonal Farm Workers, January 18-20, 1966, United States Department of State, Washington, D. C. ...

Cover title.

Equal educational opportunity for Puerto Rican children : hearings before the Select Committee on Equal Educational Opportunity of the United States Senate, Ninety-first Congress, second session, on equal educational opportunity, Washington, D.C., November 23, 24, and 25, 1970.

Reprint of the 1970 ed. published by the U.S. Govt. Print. Off., Washington, which was issued as pt. 8 of Equal educational opportunity.

Equal employment opportunity : women and minority aerospace managers and professionals, 1979-86 : report to congressional requestors /

"B-228734"--p.1.

Equal employment opportunity in Tacoma area local government : a report /

Mode of access: Internet.

Opportunity bulletins.

Mode of access: Internet.

The challenge ahead : equal opportunity in referral unions : a report of the United States Commission on Civil Rights.

Mode of access: Internet.

DOE/EPA/NSF/ONR joint program on bioremediation : interagency announcement of opportunity : Environmental Protection Agency, Department of Energy, National Science Foundation, Office of Naval Research jointly announce the availability of 1996 grants for research.

Mode of access: Internet.

A paper commitment : equal employment opportunity in the Kentucky Bureau of State Police.

July 1978.