¿Es posible crecer con equidad y en democracia?: una síntesis de la propuesta de la CEPAL

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Globalización, actores sociales y democracia en América Latina

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Salud y democracia: la experiencia de Bolivia (1982-1985)

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La democracia frente al reto del Estado eficiente

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Análisis organizacional del Partido de la Democracia Social Brasileña en el Estado de San Pablo (1988-2006)

The article represents a theoretical and methodological approach to the analysis of organizational dynamics of political parties today, based on a study of the Party of Brazilian Social Democracy (PSDB) in the State of Sao Pãulo (period between 1988 to 2006). It is hypothesized that the structure and the institutional rules of a particular party, or even their election results, are insufficient to explain the inner workings, such as the role of party organization in the electoral system. An approach that articulates the relationship patterns, election results and posts held in the party, identified the factors that explain the political capital that circulated within the party and ensured its organizational dynamics over the period analyzed.

Democracia, reformas económicas y gobernabilidad en Bolivia

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Democracia, desarrollo y participación

Discurso pronunciado por el Vicepresidente de la Republica del Ecuador y Presidente del CONADE (Consejo Nacional de Desarrollo), en la inauguracion del Seminario Internacional sobre Participacion Social en America Latina, Quito, 17 al 21 de noviembre de 1980.

Evaluation of the effects of nicorandil and its molecular precursor (without radical NO) on proliferation and apoptosis of 786-cell

Nicorandil is a nitric oxide (NO) donor used in the treatment of angina symptoms. It has also been reported to protect cells and affect the proliferation and death of cells in some tissues. The molecules that interfere with these processes can cause dysfunction in healthy tissues but can also assist in the therapy of some disorders. In this study we examined the effect of nicorandil and of the molecular precursor that does not have the NO radical (N-(beta-hydroxyethyl) nicotinamide) on the cell proliferation and death of human renal carcinoma cells (786-O) under normal oxygenation conditions. The molecular precursor was used in order to analyze the effects independents of NO. In the cytotoxicity test, nicorandil was shown to be cytotoxic at very high concentrations and it was more cytotoxic than its precursor (cytotoxic at concentrations of 2,000 and 3,000 μg/mL, respectively). We propose that the lower cytotoxicity of the precursor is due to the absence of the NO radical. In this study, the cells exposed to nicorandil showed neither statistically significant changes in cell proliferation nor increases in apoptosis or genotoxicity. The precursor generated similar results to those of nicorandil. We conclude that nicorandil causes no changes in the proliferation or apoptosis of the cell 786-O in normal oxygenation conditions. Moreover, the lack of NO radical in the precursor molecule did not show a different result, except in the cell cytotoxicity. © 2013 Springer Science+Business Media Dordrecht.

Free radical scavenging activity of Kielmeyera variabilis (Clusiaceae)

As part of our ongoing research on antioxidant agents from Brazilian flora, we screened the free radical scavenging activity of two extracts and eight fractions of Kielmeyera variabilis (Clusiaceae) using DPPH (2,2-diphenyl-1- picrylhydrazyl-hydrate) and ABTS+ [2,2'-azinobis(3- ethylenebenzothiazoline-6-sulfonic acid)] colorimetric assays. The ethyl acetate and n-butanol fractions of the leaves of K. variabilis displayed the strongest activity (IC50 of 3.5 ± 0.3 and 4.4 ± 0.2 μg mL -1 for DPPH and 6.6 ± 0.4 and 3.1 ± 0.1 μg mL -1 for ABTS+, respectively). Chromatographic fractionation of the most potent fractions led to identification of three flavonols with previously described antioxidant activity, quercitrin (1), quercetin-3-O- glucoside (3), and quercetin-3-O-galactoside (4), and of one biflavone, podocarpusflavone A (2). This is the first time that the presence of these flavonoids in Kielmeyera variabilis has been reported. © 2013 by the authors.

Una esperanzada visión de la democracia

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Las estructuras sociales y la democracia en los años noventa

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Democracia y economía

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Descentralización y democracia: el nuevo municipio latinoamericano

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Democracia y desarrollo

Discurso del Excmo. Sr. Fernando Henrique Cardoso, Presidente de la República Federativa del Brasil, en la Sede de la CEPAL, Santiago de Chile, 3 de marzo de 1995