Spectroscopy and electrochemical characterization of Langmuir-Blodgett and physical vapor thin films of 29-membered diazocrown ether 1 with two n-octyl substituents

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Trisomy X and 1 29 translocation in infertile heifers

In a group of 12 Pitangueiras breed heifers exhibiting a high return rate to service, three were noted to be carriers of the 1 29 translocation. One of the heifers exhibited trisomy for the X-chromosome in addition to the 1 29 translocation. The appearance and external genitalia of the 1 29 T; trisomy X heifer were not altered, although on rectal examination the internal genitalia, including the ovaries, appeared similar to that of a prepubertal heifer. © 1987.

Farmacovigilância no Brasil: A relação entre polimorfismo de fármacos, efetividade e segurança dos medicamentos

In spite of the stated Brazilian policy on medicines that their quality, effectiveness and safety should be ensured at reasonable cost, hospitals in the ANVISA Surveillance Network have been receiving notifications of technical complaints, adverse reactions and suspected therapeutic ineffectiveness (STI) of medicines. The purpose of this study was to identify the medicines notified for suspicion of therapeutic ineffectiveness, at a university hospital participating in the national Surveillance Network, and to investigate the existence of polymorphs of any of the drugs involved, by examining the literature. There were 31 notifications of STI in a period of 18 months, concerning 11 different drugs, all of which were 'similar' drugs (neither original nor licensed by originator); five of these could contain polymorphs, according to the literature. However, this does not mean that the other drugs could not contain some unknown polymorphs, more studies being needed on polymorphism, especially in the cases of reported therapeutic ineffectiveness. Therefore, tests of polymorphism should be made part of the routine quality control of the raw materials during the development of medicines and in the studies of pharmaceutical equivalence to 'reference' medicines (innovative brands). The stability test should also involve a study of polymorphism, in order to confirm the solid state stability of the drug. All these measures will assure the effectiveness of medicines, since the reproducibility in the quality of pharmaceutical products could be monitored, as well as the equivalence of each production batch with the batch selected to determine the bioequivalence with the reference brand.

Políticas sobre desarrollo institucional e innovación en biocombustibles en América Latina y el Caribe: Memoria del diálogo de políticas realizado en la CEPAL, Santiago, el 28 y 29 de marzo de 2011

Incluye Bibliografía

Discurso pronunciado por el Sr. Raúl Prebisch en la Cuarta Sesión de la Comisión Económica para América Latina, el 29 de mayo de 1951 en la ciudad de México, DF

Incluye Bibliografía

Acta resumida de la 70a sesión celebrada La Paz el miércoles 29 de mayo a las 11.45 horas

Incluye Bibliografía

Comité de Cooperación Sur-Sur: temario provisional, 29 de agosto de 2012

Versión en inglés disponible en Biblioteca

Committee on South-South Cooperation: provisional agenda, 29 August 2012

Spanish version available

Comité de Cooperación Sur-Sur: temario provisional anotado, 29 de agosto de 2012

Versión en inglés disponible en Biblioteca

Committee on South-South Cooperation: annotated provisional agenda, 29 August 2012

Spanish version available

Summary Record of the Seventieth Meeting Held at La Paz on Wednesday, 29 May 1957, at 11.45 a.m.

Incluye Bibliografía

Acta Resumida de la 53a. Sesión celebrada en Bogotá el lunes 29 de agosto de 1955 a las 15 horas

Incluye Bibliografía

Provisional Summary Record of the Fifty-Third Meeting held at Bogota on Monday, 29 August, 1955 at 3.20 p.m.

Incluye Bibliografía