911 resultados para Ácido retinóico : Metabolismo


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The Paraná Magmatic Province was generated by a large volcanic event occurred in the Lower Cretaceous, it was a phenomenon that preceded the fragmentation of the supercontinent Gondwana. In Brazil the volcanic rocks overlying about 75% of the surface of the Parana basin being the Serra Geral Formation essentially represented by basalts and andesites of tholeiitic nature and subordinate porphyritic rhyodacites, called Chapecó type and aphyric rhyolites, Palms type. Based on the chemical compositions, rocks of Palmas type are subdivided into Santa Maria, Clevelândia, Caxias do Sul, Jacuí and Anita Garibaldi. Rocks of Chapecó type are grouped into three distinct subtypes called Guarapuava, Tamarana and Ourinhos. These acidic rocks that overlying basalts are of two main types: high-Ti (Paranapanema, Pitanga and Urubici) and low-Ti (Gramado, Esmeralda and Ribeira). Representative profiles of these rocks were studied in detail in order to establish the lithostratigraphy and Chemostratigraphy of Palmas and Chapecó type. To do this was made a field work and the use of a database with 1109 samples with their geographical coordinates and geochemical information of major and trace elements, which were launched in maps generated by Google Earth. From these maps, it was verified that rocks of the Palmas type are distributed predominantly in the south region of the basin in the state of Rio Grande do Sul, accumulated along Torres Syncline, while those Chapecó type occur in the plateaus of midwestern Paraná, in this region was observed that Chapecó type overlap those Palmas type. In the profiles studied, within Palmas type, Caxias do Sul type is spread throughout the southern region of the basin, occurring at the base of the acid volcanic sequences, in other words, they are older compared to the others. It was also observed that the rocks of Santa Maria and Anita Garibaldi type occupy the top of the sequences, both covering rocks of Caxias do Sul..

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Pós-graduação em Odontologia Restauradora - ICT

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Two experiments (E) were carried out with the objective of evaluating the effects of fumaric acid and carbo-amino-fosfo-quelato of calcium diets of weaned pigs on performance (E1) and intestinal morphology (E2). A total of 96 and 32 pigs with initial mean weights of 5,66 kg ± 0,44kg and 5,34 ± 0,45kg , in E1 and in E2, were used respectively. Randomized block designs were used in both experiments, with a 2 X 2 factorial arrangement in E1 and a 2 X 2 X 2 factorial arrangement in E2. No interaction between acidifier, source of calcium and phosphorus were found for the variables studied in the two experiments. No treatment effects were found on daily feed intake in evaluating periods. Feed conversion from 0 to 17 days was better (P<0.05) when inorganic sources of Ca and P were fed; however, no difference was observed in other periods. The averages of villus height (AV), crypt depth (PC), AV: PC relationship and mucous membrane of the duodenum and of the jejunum didn’t differ among treatments. Considering the total nursery period, no benefit was found in using an acidifier, however the carbo-amino-fosfo-quelato of calcium studied may replace the inorganic sources in the diets of piglets, with no damage to performance and to intestinal morphology.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The aim of this work was to evaluate the application of different concentrations of ascorbic acid on Orange Flesh melon. Whole Melons were sanifi ed with 500 mg L-1 of sodium hypochlorite for 10 minutes and the cuts into cubes with 100 mg L-1 for 1 minute before being tested under different concentrations of ascorbic acid (0, 1, 2 and 3%) in immersion at room temperature for 10 minutes. After drainage, the cuts were packed in PET packages lined with polyethylene fi lm of 18 µm and stored at 5 ± 1°C and 85 ± 5% of RH for 8 days, being evaluated every 2 days. Physicochemical, microbiological and sensorial analyses were performed. The experimental design utilized for the experiment was the completely randomized in factorial scheme. Ten replicates were used for non-destructive analyses and 3 replicates were used for destructive ones. The application of ascorbic acid reduced the loss of mass; the fruits presented a low population of psychrotrophic bacterias, fi lamentous, fungi and yeasts, reduction of soluble solids, pH and fi rmness and, consequently, extended postharvest life of the fruits by 2 days. The appearance, fl avor and taste were also affected. The application of 1% of ascorbic acid was the best treatment for the fresh cuts “Orange Flesh” melons.

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In the postharvest management, the fruits can be exposed to injuries that depreciated the quality and the shelf life. Thus, it was evaluated the modified atmosphere effects on guavas var. Paluma subjected to different mechanical damages. Once harvested, the fruits were selected, sanitized and submitted to the treatments T1 (control) - without injuries or packaging in bags of low density polyethylene (LDPE); T2 - without injuries + LDPE bags; T3 - damage by fall of 1 m + LDPE bags; T4 - damage by compression of 9 N + LDPE bags; T5 - damage by fall of 1 m + damage by compression of 9 N + LDPE bags and T6 - damage by fall of 1 m + damage by compression of 9 N without LDPE bags. The treatments were kept in cold storage at 10 ± 1 o C and 94 ± 2% de R.H. The analysis of CO2/ethylene production, enzymatic activity, total and soluble pectins, pulp firmness, titratable acidity (TA), soluble solids (SS), reducing sugars and ascorbic acid were performed every 10 days of refrigeration, and an additional day outside cold storage (22 ± 1o C and 75 ± 3% R.H.) for 30 days. Guavas packed in LDPE bags, not subject to mechanical damage, presented the best quality standards. The fruits suffered only one kind of damage, when packaged, presented satisfactory pattern compared to the fruits without package and not exposed to any mechanical damages. Applying the two kinds of damages, the LDPE packaging was not adequate to decrease the metabolic rate of these fruits, making them unfit for marketing.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB