Desenvolvimento de uma aplicação multimédia como ferramenta terapêutica

Dissertação para obtenção do Grau de Mestre em Engenharia Electrotécnica e de Computadores

Supporting NAT traversal and secure communications in a protocol implementation framework

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do Grau de Mestre em Engenharia Electrotécnica e de Computadores

Integration of repositories in elearning systems

The wide acceptance of digital repositories today in the eLearning field raises several interoperability issues. In this paper we present the interoperability features of a service oriented repository of learning objects called crimsonHex. These features are compliant with the existing standards and we propose extensions to the IMS interoperability recommendation, adding new functions, formalizing message interchange and providing also a REST interface. To validate the proposed extensions and its implementation in crimsonHex we developed a repository plugin for Moodle 2.0 that is expected to be included in the next release of this popular learning management system.

Myoelectric Signal Monitoring System

The Electromyography (EMG) is an important tool for gait analyzes and disorders diagnoses. Traditional methods involve equipment that can disturb the analyses, being gradually substituted by different approaches, like wearable and wireless systems. The cable replacement for autonomous systems demands for technologies capable of meeting the power constraints. This work presents the development of an EMG and kinematic data capture wireless module, designed taking into account power consumption issues. This module captures and converts the analog myoeletric signal to digital, synchronously with the capture of kinetic information. Both data are time multiplexed and sent to a PC via Bluetooth link. The work carried out comprised the development of the hardware, the firmware and a graphical interface running in an external PC. The hardware was developed using the PIC18F14K22, a low power family of microcontrollers. The link was established via Bluetooth, a protocol designed for low power communication. An application was also developed to recover and trace the signal to a Graphic User Interface (GUI), coordinating the message exchange with the firmware. Results were obtained which allowed validating the conceived system in static and with the subject performing short movements. Although it was not possible to perform the tests within more dynamic movements, it is shown that it is possible to capture, transmit and display the captured data as expected. Some suggestions to improve the system performance also were made.

A Methodology for Creating an Adapted Command Language for Driving an Intelligent Wheelchair

Intelligent wheelchairs (IW) are technologies that can increase the autonomy and independence of elderly people and patients suffering from some kind of disability. Nowadays the intelligent wheelchairs and the human-machine studies are very active research areas. This paper presents a methodology and a Data Analysis System (DAS) that provides an adapted command language to an user of the IW. This command language is a set of input sequences that can be created using inputs from an input device or a combination of the inputs available in a multimodal interface. The results show that there are statistical evidences to affirm that the mean of the evaluation of the DAS generated command language is higher than the mean of the evaluation of the command language recommended by the health specialist (p value = 0.002) with a sample of 11 cerebral palsy users. This work demonstrates that it is possible to adapt an intelligent wheelchair interface to the user even when the users present heterogeneous and severe physical constraints.

A Rat Model of Diabetic Wound Infection for the Evaluation of Topical Antimicrobial Therapies

Diabetes mellitus is an epidemic multisystemic chronic disease that frequently is complicated by complex wound infections. Innovative topical antimicrobial therapy agents are potentially useful for multimodal treatment of these infections. However, an appropriately standardized in vivo model is currently not available to facilitate the screening of these emerging products and their effect on wound healing. To develop such a model, we analyzed, tested, and modified published models of wound healing. We optimized various aspects of the model, including animal species, diabetes induction method, hair removal technique, splint and dressing methods, the control of unintentional bacterial infection, sampling methods for the evaluation of bacterial burden, and aspects of the microscopic and macroscopic assessment of wound healing, all while taking into consideration animal welfare and the '3Rs' principle. We thus developed a new wound infection model in rats that is optimized for testing topical antimicrobial therapy agents. This model accurately reproduces the pathophysiology of infected diabetic wound healing and includes the current standard treatment (that is, debridement). The numerous benefits of this model include the ready availability of necessary materials, simple techniques, high reproducibility, and practicality for experiments with large sample sizes. Furthermore, given its similarities to infected-wound healing and treatment in humans, our new model can serve as a valid alternative for applied research.

mRPL: Boosting mobility in the Internet of Things

The 6loWPAN (the light version of IPv6) and RPL (routing protocol for low-power and lossy links) protocols have become de facto standards for the Internet of Things (IoT). In this paper, we show that the two native algorithms that handle changes in network topology – the Trickle and Neighbor Discovery algorithms – behave in a reactive fashion and thus are not prepared for the dynamics inherent to nodes mobility. Many emerging and upcoming IoT application scenarios are expected to impose real-time and reliable mobile data collection, which are not compatible with the long message latency, high packet loss and high overhead exhibited by the native RPL/6loWPAN protocols. To solve this problem, we integrate a proactive hand-off mechanism (dubbed smart-HOP) within RPL, which is very simple, effective and backward compatible with the standard protocol. We show that this add-on halves the packet loss and reduces the hand-off delay dramatically to one tenth of a second, upon nodes’ mobility, with a sub-percent overhead. The smart-HOP algorithm has been implemented and integrated in the Contiki 6LoWPAN/RPL stack (source-code available on-line mrpl: smart-hop within rpl, 2014) and validated through extensive simulation and experimentation.

Temporomandibular Joint Ankylosis in an Infant: A Rare Cause of Difficult Airway

1.Pre-assessment data of the patient A 2-year-old boy, weighing 15 kg was admitted with a history of limited mouth opening(inter-incisor distance of 6 mm), hypoplastic and retrognathic mandible (bird face deformity) and facial asymmetry from left temporomandibular joint ankylosis (TMJA). He was born at term, after an uneventful pregnancy, and there was no report of trauma during caesarean section. No other possible aetiologies were identified. He was scheduled for mandibular osteotomy. Preoperative ENT examination revealed adenotonsillar hypertrophy. 2. Anaesthetic Plan A fiberoptic nasal intubation was performed under deep inhalation anaesthesia with sevoflurane, with the patient breathing spontaneously. Midazolam (0.05 mg.kg-1) and alfentanil (0.03 mg.kg-1) were given and anaesthesia was maintained with O2/air and sevoflurane. No neuromuscular blocking agent was administered since the surgical team needed facial nerve monitoring. 3. Description of incident During surgery an accidental extubation occurred and an attempt was made to reintubate the trachea by direct laryngoscopy. Although the osteotomy was nearly completed, the vocal cords could not be visualized (Cormack-Lehane grade IV laryngoscopic view). 4. Solving the problem Re-intubation was finally accomplished with the flexible fiberscope and the procedure was concluded without any more incidents. Extubation was performed 24 hours postoperatively with the patient fully awake. After surgery mouth opening improved to inter-incisor gap of 15 mm. 5. Lessons learned and take home message Two airways issues present in this case can lead to difficultventilation and intubation: TMJA and adenotonsillar hypertrophy. These difficulties were anticipated and managed accordingly. The accidental extubation brought to our attention the fact that, even after surgical correction, this airway remains challenging. Even with intensive jaw stretchingexercises there is a high incidence of re-ankylosis, especially in younger patients. One should bear that in mind when anaesthetizing patients with TMJA.

Contributos de um jogo tipo peddy paper na motivação de alunos para aprendizagens do tema sol-terra-vida

Este estudo tem como objetivo principal conhecer, analisar e refletir sobre as conceções e as práticas de sala de aula, relativamente à importância dos jogos como ferramenta motivadora para a aprendizagem de novos conteúdos. Numa primeira parte deste documento, é feita uma abordagem teórica sobre as questões que levaram à realização deste projeto. Numa segunda parte apresenta-se o estudo empírico que inclui a recolha do testemunho de alunos que realizaram as atividades propostas, bem como as suas expetativas acerca do uso do jogo na sala de aula. Foi utilizado o processo metodológico de investigação – ação. A recolha de dados baseouse em: observação direta, narrativa descritiva de toda a aula baseada nas Narrações Multimodais; questionário de resposta aberta e registos fotográficos, sobre os quais faremos uma análise qualitativa. Nas partes seguintes deste documento apresenta-se a análise de dades, que foi de natureza qualitativa, as conclusões e as limitações.

O planeamento estratégico como instrumento de melhoria da comunicação organizacional interna

O planeamento estratégico é uma ferramenta usada pelas empresas, como forma de contribuir para a melhoria do seu desempenho, preconizando a concretização de objetivos. A comunicação organizacional interna é um o instrumento que, para além de traduzir uma mensagem enviada aos vários indivíduos da empresa, ajuda a interpretação dessa mensagem. Este estudo tem como objetivo perceber se, o planeamento estratégico pode ser um instrumento de melhoria conceptual e de gestão da comunicação organizacional interna. Neste trabalho utilizamos uma metodologia de estudo de caso único, suportada através do método qualitativo, com recurso a entrevistas, e do método quantitativo, através de questionários estruturados. As entrevistas aos quadros superiores da empresa foram realizadas com recuso a uma análise de conteúdo, verificando-se ser de extrema importância para a gestão, tanto o planeamento estratégico, como a comunicação interna. Os instrumentos de medida usados permitiram concluir que existem, ainda, algumas lacunas de planeamento e comunicação da empresa analisada. Da análise do caso em estudo é percetível que o planeamento estratégico, como a comunicação organizacional interna, são instrumentos usados com um nível de sucesso suficiente para colocar a empresa no rumo certo e estável de mercado. Por último, entendemos que no âmbito da conciliação dos dois temas, o planeamento estratégico facilita uma comunicação mais fluída, podendo, assim, ser um instrumento de melhoria da comunicação interna. Como limitações deste trabalho relatamos, em especial, a necessária precaução da generalização dos resultados obtidos e a dificuldade em realizar uma análise mais ampla na discussão de resultados, devido aos parcos trabalhos internacionais e, sobretudo, nacionais. A principal originalidade deste estudo decorre de ser utilizada uma análise com triangulação metodológica e o facto de a unidade de análise em estudo ser uma empresa líder na sua área de negócio e setor.

Deletions within COL11A1 in Type 2 Stickler Syndrome Detected by Multiplex Ligation - Syndrome Detected by Multiplex Ligation Dependent Probe Amplification (MLPA)

Background: COL11A1 is a large complex gene around 250 kb in length and consisting of 68 exons. Pathogenic mutations in the gene can result in Stickler syndrome, Marshall syndrome or Fibrochondrogenesis. Many of the mutations resulting in either Stickler or Marshall syndrome alter splice sites and result in exon skipping, which because of the exon structure of collagen genes usually leaves the message in-frame. The mutant protein then exerts a dominant negative effect as it co-assembles with other collagen gene products. To date only one large deletion of 40 kb in the COL11A1, which was detected by RT-PCR, has been characterized. However, commonly used screening protocols, utilizing genomic amplification and exon sequencing, are unlikely to detect such large deletions. Consequently the frequency of this type of mutation is unknown. Case presentations: We have used Multiplex Ligation-Dependent Probe Amplification (MLPA) in conjunction with exon amplification and sequencing, to analyze patients with clinical features of Stickler syndrome, and have detected six novel deletions that were not found by exon sequencing alone. Conclusion: Exon deletions appear to represent a significant proportion of type 2 Stickler syndrome. This observation was previously unknown and so diagnostic screening of COL11A1 should include assays capable of detecting both large and small deletions, in addition to exon sequencing.

Social Media Integration in Video Games GameNshare: A Social Overlay for Desktop Games

The ever increasing popularity of social media makes it a promising source for the personalization of gameplay experiences. Furthermore, involving social network friends in a game can greatly enrich the satisfaction of the player and also attract potential novel players to a game. This master thesis describes a social overlay designed for desktop games, called GameNshare. It allows players to easily capture and share with multiple social networks game-related screenshots, videos and stories. Additionally, it also provides asynchronous multiplayer game mechanics to directly integrate social network friends in the game. GameNshare was designed to interact with the users in a non-intrusive way allowing them to be in complete control of what is shared. It prevents unsolicited sharing of messages, a key problem in social media integration tools, by the use of built-in message monitoring and anti-spam measures. GameNshare was specially designed for players aged from 18 to 25 years that are regular users of Twitter and Facebook. It was tested by a group of 10 individuals from the target age range that were surveyed to capture their insights on the use of the social overlay. The implemented GameNshare features were well accepted by the testers that were also useful in highlighting features for future development. GameNshare ultimate goal is to make players look and ask for social integration and allow them to take full advantage of their social communities to improve gaming experiences.

Interfaces for television content sharing and annotation

Dissertação para obtenção do Grau de Mestre em Engenharia Informática

Sentiment analysis on twitter for the portuguese language

Dissertação para obtenção do Grau de Mestre em Engenharia Informática

Ciberformance: a performance em ambientes e mundos virtuais

Tese apresentada para cumprimento dos requisitos necessários à obtenção do grau de Doutor em Ciências da Comunicação