999 resultados para ddc: 004.22


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In the search for new soil stabilizing agents the effects of six organic cations on plastic limit, liquid limit, shrinkage limit, air-dry strength and rate of slaking of a highly plastic clay subsoil were studied. In all cases the plasticity index and shrinkage were reduced by the treatments. The air-dry strength was lowered in varying degree, which was the only undesirable effect noted. With one exception resistance to slaking was improved. It is concluded that large organic cations show promise as possible stabilizing agents for highly plastic fine-grained soils.

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Dit avoir reçu une lettre de Ullmann "qui [les] intéresse" et prie son ami de "venir en causer" avec lui

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Se demande comment il pourrait changer sa loge contre une baignoire de face

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Eretria war eine der grossen Städte des antiken Griechenland. Zahlreiche Monumente und Kunstwerke zeugen noch heute von ihrer bedeutenden Vergangenheit. 1964 haben Archäologen aus der Schweiz die Erforschung der antiken Stadt, die vor über einem Jahrhundert begonnen hatte, in enger Zusammenarbeit mit den zuständigen griechischen Behörden aufgenommen. Zum ersten Mal sollen nun die bisherigen Ergebnisse in der Schweiz präsentiert werden: Die Ausstellung lässt anhand von etwa 500 Ausgrabungsfunden eine blühende griechische Stadt wieder aufleben. Eretria war von Anfang an ein wichtiger Knotenpunkt zwischen Ost und West. Die Stadt liegt am östlichen Ufer des Golfes von Euböa gegenüber von Attika. Von diesem zentralen Punkt in der Ägäis brachen eretrische Abenteurer ab dem 8. Jh. v. Chr. auf, um das gesamte Mittelmeer zu durchkreuzen. Obschon Eretria zur Zeit der Perserkriege um 490 v. Chr. und unter der athenischen Herrschaft im 5. Jh. gelitten hatte, erlebte die Stadt in den folgenden Jahrhunderten eine neue Blütezeit, die sich bis in die römische Kaiserzeit fortsetzte. Erst im 6. Jh. n. Chr. wird der Ort vollständig verlassen. Die Stadt der Lebenden stellt anschaulich die verschiedenen Bereiche des Lebens in einer antiken griechischen Stadt vor. Anhand der Wohnhäuser der eretrischen Aristokratie wird das Privatleben thematisiert. Im Gegensatz zu den Privathäusern, die nach aussen geschlossen sind, öffnen sich die öffentlichen Gebäude auf grosse Plätze. Die Agora, die Säulenhallen, das Theater, die Palästren und das Gymnasion bieten den Einwohnern genügend Raum, um sich zu treffen, über Politik und Kultur zu debattieren und Neuigkeiten auszutauschen. Die Stadt der Götter zeigt, welche Götter man in Eretria verehrte. Im Zentrum Eretrias befand sich das Heiligtum des Apollon Daphnephoros (= <des Lorbeerträgers>). Der Stadtgott Apollon teilte sich mit seiner Zwillingsschwester Artemis die Vorrangstellung im eretrischen Pantheon. Daneben hatten aber auch andere Götter ihren Platz: Athena auf der Akropolis, Demeter und Kore an deren Abhängen und Dionysos beim Theater. Die Stadt der Toten geht auf die Jenseitsvorstellungen und auf die Bestattungsbräuche der damaligen Menschen ein. Die oberirdischen Monumente sind seit langem verschwunden. Die eigentlichen Gräber in der Tiefe der Erde mit den sterblichen Überresten und den Grabbeigaben blieben indes intakt. Sie lehren uns viel über die Gesellschaft Eretrias und über das Verhältnis der Menschen zum Tod. Begleitpublikation zur Ausstellung "ausgegraben! Schweizer Archäologen erforschen die griechische Stadt Eretria", die vom 22. September 2010 bis zum 30. Januar 2011 im Antikenmuseum Basel und Sammlung Ludwig gezeigt wurde.

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To evaluate the impact of noninvasive ventilation (NIV) algorithms available on intensive care unit ventilators on the incidence of patient-ventilator asynchrony in patients receiving NIV for acute respiratory failure. Prospective multicenter randomized cross-over study. Intensive care units in three university hospitals. Patients consecutively admitted to the ICU and treated by NIV with an ICU ventilator were included. Airway pressure, flow and surface diaphragmatic electromyography were recorded continuously during two 30-min periods, with the NIV (NIV+) or without the NIV algorithm (NIV0). Asynchrony events, the asynchrony index (AI) and a specific asynchrony index influenced by leaks (AIleaks) were determined from tracing analysis. Sixty-five patients were included. With and without the NIV algorithm, respectively, auto-triggering was present in 14 (22%) and 10 (15%) patients, ineffective breaths in 15 (23%) and 5 (8%) (p = 0.004), late cycling in 11 (17%) and 5 (8%) (p = 0.003), premature cycling in 22 (34%) and 21 (32%), and double triggering in 3 (5%) and 6 (9%). The mean number of asynchronies influenced by leaks was significantly reduced by the NIV algorithm (p < 0.05). A significant correlation was found between the magnitude of leaks and AIleaks when the NIV algorithm was not activated (p = 0.03). The global AI remained unchanged, mainly because on some ventilators with the NIV algorithm premature cycling occurs. In acute respiratory failure, NIV algorithms provided by ICU ventilators can reduce the incidence of asynchronies because of leaks, thus confirming bench test results, but some of these algorithms can generate premature cycling.

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Background To analyse the extent and profile of outpatient regular dispensation of antipsychotics, both in combination and monotherapy, in the Barcelona Health Region (Spain), focusing on the use of clozapine and long-acting injections (LAI). Methods Antipsychotic drugs dispensed for people older than 18 and processed by the Catalan Health Service during 2007 were retrospectively reviewed. First and second generation antipsychotic drugs (FGA and SGA) from the Anatomical Therapeutic Chemical classification (ATC) code N05A (except lithium) were included. A patient selection algorithm was designed to identify prescriptions regularly dispensed. Variables included were age, gender, antipsychotic type, route of administration and number of packages dispensed. Results A total of 117,811 patients were given any antipsychotic, of whom 71,004 regularly received such drugs. Among the latter, 9,855 (13.9%) corresponded to an antipsychotic combination, 47,386 (66.7%) to monotherapy and 13,763 (19.4%) to unspecified combinations. Of the patients given antipsychotics in association, 58% were men. Olanzapine (37.1%) and oral risperidone (36.4%) were the most common dispensations. Analysis of the patients dispensed two antipsychotics (57.8%) revealed 198 different combinations, the most frequent being the association of FGA and SGA (62.0%). Clozapine was dispensed to 2.3% of patients. Of those who were receiving antipsychotics in combination, 6.6% were given clozapine, being clozapine plus amisulpride the most frequent association (22.8%). A total of 3.800 patients (5.4%) were given LAI antipsychotics, and 2.662 of these (70.1%) were in combination. Risperidone was the most widely used LAI. Conclusions The scant evidence available regarding the efficacy of combining different antipsychotics contrasts with the high number and variety of combinations prescribed to outpatients, as well as with the limited use of clozapine. Background To analyse the extent and profile of outpatient regular dispensation of antipsychotics, both in combination and monotherapy, in the Barcelona Health Region (Spain), focusing on the use of clozapine and long-acting injections (LAI). Methods Antipsychotic drugs dispensed for people older than 18 and processed by the Catalan Health Service during 2007 were retrospectively reviewed. First and second generation antipsychotic drugs (FGA and SGA) from the Anatomical Therapeutic Chemical classification (ATC) code N05A (except lithium) were included. A patient selection algorithm was designed to identify prescriptions regularly dispensed. Variables included were age, gender, antipsychotic type, route of administration and number of packages dispensed. Results A total of 117,811 patients were given any antipsychotic, of whom 71,004 regularly received such drugs. Among the latter, 9,855 (13.9%) corresponded to an antipsychotic combination, 47,386 (66.7%) to monotherapy and 13,763 (19.4%) to unspecified combinations. Of the patients given antipsychotics in association, 58% were men. Olanzapine (37.1%) and oral risperidone (36.4%) were the most common dispensations. Analysis of the patients dispensed two antipsychotics (57.8%) revealed 198 different combinations, the most frequent being the association of FGA and SGA (62.0%). Clozapine was dispensed to 2.3% of patients. Of those who were receiving antipsychotics in combination, 6.6% were given clozapine, being clozapine plus amisulpride the most frequent association (22.8%). A total of 3.800 patients (5.4%) were given LAI antipsychotics, and 2.662 of these (70.1%) were in combination. Risperidone was the most widely used LAI. Conclusions The scant evidence available regarding the efficacy of combining different antipsychotics contrasts with the high number and variety of combinations prescribed to outpatients, as well as with the limited use of clozapine.

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BACKGROUND: The aim of this study was to evaluate the effect of CD4+ T-cell counts and other characteristics of HIV-infected individuals on hepatitis C virus (HCV) RNA levels. METHODS: All HIV-HCV-coinfected Swiss HIV Cohort Study participants with available HCV RNA levels and concurrent CD4+ T-cell counts before starting HCV therapy were included. Potential predictors of HCV RNA levels were assessed by multivariate censored linear regression models that adjust for censored values. RESULTS: The study included 1,031 individuals. Low current and nadir CD4+ T-cell counts were significantly associated with higher HCV RNA levels (P = 0.004 and 0.001, respectively). In individuals with current CD4+ T-cell counts < 200/microl, median HCV RNA levels (6.22 log10 IU/ml) were +0.14 and +0.24 log10 IU/ml higher than those with CD4+ T-cell counts of 200-500/microl and > 500/microl. Based on nadir CD4+ T-cell counts, median HCV RNA levels (6.12 log10 IU/ml) in individuals with < 200/microl CD4+ T-cells were +0.06 and +0.44 log10 IU/ml higher than those with nadir T-cell counts of 200-500/microl and > 500/microl. Median HCV RNA levels were also significantly associated with HCV genotype: lower values were associated with genotype 4 and higher values with genotype 2, as compared with genotype 1. Additional significant predictors of lower HCV RNA levels were female gender and HIV transmission through male homosexual contacts. In multivariate analyses, only CD4+ T-cell counts and HCV genotype remained significant predictors of HCV RNA levels. Conclusions: Higher HCV RNA levels were associated with CD4+ T-cell depletion. This finding is in line with the crucial role of CD4+ T-cells in the control of HCV infection.