Aníbal Pinto Santa Cruz

Aníbal Pinto Santa Cruz, Director of the Review since 1986, died on 3 January. His death fills us with profound grief and leaves a deep vacuum in this organization. The Economic Commission for Latin America and the Caribbean benefited for many years from the intellectual sparkle and human warmth of Mr. Pinto, who served for several years as Director of the Economic Development Division. What is more, he was one of the personalities who gave the ECLAC secretariat a clear institutional identity. The depth and clarity of his analyses of Chile and its development process were matched by his real dedication to Latin America, which inspired him to make solid and valuable contributions to the progress of ideas in our region. He belonged in his own right to the select group of those thinkers whose new categories and concepts afford others a richer vision of reality. It is not surprising, therefore, that followers and former students of his abound in the region. A person of great intellectual generosity, impatient with conventional wisdom and intolerance from all academic and political quarters, Aníbal Pinto received recognition from the international academic community, as embodied in the Raúl Prebisch Ibero­American Prize in Economics, an honorary doctorate from the University of Campinas, Brazil, and the Chilean National Prize in the Humanities and Social Sciences for 1995. In recent months he received two further distinctions: first, a tribute from his ECLAC colleagues on the occasion of the fiftieth anniversary of the United Nations, and second, a collection of his writings published by the Universidad Nacional Autónoma de México which was presented to him in a ceremony held at the Santiago Book Fair in December 1995. ECLAC has been immensely fortunate in having among its senior officials great personalities who have left behind a legacy of values, principles and key ideas; institution­builders, if you will. If there is anything which distinguishes ECLAC from other United Nations bodies, it is this. Aníbal Pinto's name will undoubtedly be among those which resound the loudest. For this reason, and for his exceptional human qualities, we shall remember him with affection and admiration.

Aníbal Pinto Santa Cruz

El 3 de enero falleció don Aníbal Pinto Santa Cruz, desde 1986 Director de esta Revista. El hecho nos invade de profundo pesar, y deja un hondo vacío en la institución. La Comisión Económica de las Naciones Unidas para América Latina y el Caribe se benefició por muchos años del brillo intelectual y la calidad humana de Don Aníbal, quien por varios años se desempeñó como Director de la División de Desarrollo Económico. Más que eso, fue una de las personalidades que le dio una clara identidad institucional a la Secretaría de la CEPAL. A la profundidad y lucidez de sus análisis sobre Chile y su proceso de desarrollo, unía una auténtica vocación latinoamericana, que lo llevó a realizar sólidos y valiosos aportes al progreso de las ideas en nuestra región. Pertenecía por derecho propio al selecto grupo de aquellos pensadores que mediante nuevas categorías y conceptos abren a los demás una visión enriquecida de la realidad. No es sorprendente, por lo tanto, que en toda la región existan discípulos y ex alumnos suyos. Persona de gran generosidad intelectual e impaciencia ante el saber convencional y las intolerancias de cualquier lado del espectro académico o político, Aníbal Pinto recibió el reconocimiento de la comunidad académica internacional, expresado en el Premio Iberoamericano de Economía "Raúl Prebisch", el Doctorado Honoris Causa de la Universidad de Campinas, en Brasil, y el Premio Nacional de Humanidades y Ciencias Sociales de Chile, 1995. En meses recientes, recibió dos distinciones adicionales: la primera, de sus colegas de la CEPAL, que le rindieron un homenaje con ocasión del quincuagésimo aniversario de las Naciones Unidas; la segunda, al presentarse una recopilación de sus escritos publicada por la Universidad Nacional Autónoma de México en un acto que se llevó a cabo en la Feria del Libro de Santiago, en diciembre pasado. La CEPAL ha tenido la infinita suerte de contar entre sus cuadros con grandes personalidades que han dejado un legado de valores, principios e ideas-fuerza; si se quiere, forjadores de instituciones. Es más, si hay algo que distingue a la CEPAL del resto de las entidades de las Naciones Unidas, es ese hecho. Entre los nombres que más resonarán, sin duda figurará el de Aníbal Pinto. Por eso, y por sus excepcionales cualidades humanas, lo recordaremos con afecto y admiración.

Anti-Candida properties of urauchimycins from actinobacteria associated with Trachymyrmex ants

After decades of intensive searching for antimicrobial compounds derived from actinobacteria, the frequency of isolation of new molecules has decreased. To cope with this concern, studies have focused on the exploitation of actinobacteria from unexplored environments and actinobacteria symbionts of plants and animals. In this study, twenty-four actinobacteria strains isolated from workers of Trachymyrmex ants were evaluated for antifungal activity towards a variety of Candida species. Results revealed that seven strains inhibited the tested Candida species. Streptomyces sp. TD025 presented potent and broad spectrum of inhibition of Candida and was selected for the isolation of bioactive molecules. From liquid shake culture of this bacterium, we isolated the rare antimycin urauchimycins A and B. For the first time, these molecules were evaluated for antifungal activity against medically important Candida species. Both antimycins showed antifungal activity, especially urauchimycin B. This compound inhibited the growth of all Candida species tested, with minimum inhibitory concentration values equivalent to the antifungal nystatin. Our results concur with the predictions that the attine ant-microbe symbiosis may be a source of bioactive metabolites for biotechnology and medical applications. © 2013 Thais D. Mendes et al.

Genes expressed in dental enamel development are associated with molar-incisor hypomineralization

Genetic disturbances during dental development influence variation of number and shape of the dentition. In this study, we tested if genetic variation in enamel formation genes is associated with molar-incisor hypomineralization (MIH), also taking into consideration caries experience. DNA samples from 163 cases with MIH and 82 unaffected controls from Turkey, and 71 cases with MIH and 89 unaffected controls from Brazil were studied. Eleven markers in five genes [ameloblastin (AMBN), amelogenin (AMELX), enamelin (ENAM), tuftelin (TUFT1), and tuftelin-interacting protein 11 (TFIP11)] were genotyped by the TaqMan method. Chi-square was used to compare allele and genotype frequencies between cases with MIH and controls. In the Brazilian data, distinct caries experience within the MIH group was also tested for association with genetic variation in enamel formation genes. The ENAM rs3796704 marker was associated with MIH in both populations (Brazil: p = 0.03; OR = 0.28; 95% C.I. = 0.06-1.0; Turkey: p = 1.22e-012; OR = 17.36; 95% C.I. = 5.98-56.78). Associations between TFIP11 (p = 0.02), ENAM (p = 0.00001), and AMELX (p = 0.01) could be seen with caries independent of having MIH or genomic DNA copies of Streptococcus mutans detected by real time PCR in the Brazilian sample. Several genes involved in enamel formation appear to contribute to MIH. © 2013.

Degree of conversion and hardness of two different systems of the vitrebond™ glass ionomer cement light cured with blue LED

This study investigated the physicochemical properties of the new formulation of the glass ionomer cements through hardness test and degree of conversion by infrared spectroscopy (FTIR). Forty specimens (n = 40) were made in a metallic mold (4 mm diameter × 2 mm thickness) with two resin-modified glass ionomer cements, Vitrebond™ and Vitrebond™ Plus (3M/ ESPE). Each specimen was light cured with blue LED with power density of 500 mW/cm2during 30 s. Immediately after light curing, 24h, 48h and 7 days the hardness and degree of conversion was determined. The Vickers hardness was performed by the MMT-3 microhardness tester using load of 50 gm force for 30 seconds. For degree of conversion, the specimens were pulverized, pressed with KBr and analyzed with FT-IR (Nexus 470). The statistical analysis of the data by ANOVA showed that the Vitrebond™ and Vitrebond™ Plus were no difference significant between the same storage times (p > 0.05). For degree of conversion, the Vitrebond™ and Vitrebond™ Plus were statistically different in all storage times after light curing. The Vitrebond™ showed higher values than Vitrebond™ Plus (p < 0.05). The performance of Vitrebond™ had greater results for degree of conversion than Vitrebond™ Plus. The correlation between hardness and degree of conversion was no evidence in this study.

Influence of artificial aging in marginal adaptation of mixed class V cavities

The aim of this study was to investigate whether the artificial aging by thermal cycling had influenced the marginal adaptation of class V restorations with/without chlorhexidine application in the bond process. Twelve intact human third molars were used. Class V cavity preparations were performed on the buccal surface and the teeth received 35% phosphoric acid-etching procedure (Ultradent Products Inc., South Jordan, Utah, USA). Subsequently, the samples were divided in two groups: Untreated acid-etched dentin and chlorhexidine application as an adjunct in the bond process. The adhesive Single Bond 2 (3M ESPE, St. Paul, MN, USA) was used after 2% chlorhexidine application, and the restorations were performed with FiltekTM Z350 XT (3M ESPE) composite resin. The specimens were submitted to artificial aging by thermal cycling with 3,000 cycles. Analyzes were performed on scanning electron microscopy using replicas of marginal adaptation in percentage of continuous margin before and after the artificial aging. The data were analyzed by paired test and the results showed statistically significant differences in the percentage of continuous margin with/without chlorhexidine treatment before and after thermal cycling. This study concluded that the artificial aging by thermal cycling influenced the marginal adaptation of mixed class V composite restorations.

High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from late-onset preeclampsia

Preeclampsia (PE), a specific syndrome of pregnancy, can be classified into early and late onset, depending on whether clinical manifestations occur before or after 34 weeks' gestation. We determined whether plasma concentrations of Hsp60 and Hsp70 were related to circulating cytokine levels, as well as kidney and liver functions, in early- and late-onset PE. Two hundred and thirty-seven preeclamptic women (95 with early- and 142 with late-onset PE) were evaluated. Plasma levels of Hsp60, Hsp70, and their specific antibodies, tumor necrosis factor-alpha (TNF-α), interleukin (IL)-1, IL-10, IL-12, and soluble TNF-α-receptor I (sTNFRI) concentrations, were determined by enzyme-linked immunosorbent assay (ELISA). Concentrations of Hsp70, TNF-α, IL-1β, IL-12, and sTNFRI were significantly elevated in patients with early-onset PE compared with women with late-onset PE; IL-10 levels were significantly lower in the early-onset PE group. Concentrations of urea, uric acid, proteinuria, glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), and lactate dehydrogenase (LDH) were also significantly higher in early-onset PE. The percentage of infants with intrauterine growth restriction was also significantly higher in women with early-onset PE. There were positive correlations between Hsp70 levels and TNF-α, TNFRI, IL-1β, IL-12, GOT, GPT, LDH, and uric acid concentrations in early-onset PE group. Thus, early-onset PE was associated with greater maternal and fetal impairment. There are differences in pathophysiology between early- and late-onset PE, highlighting by the difference in Hsp70 levels. © 2013 Elsevier B.V. All rights reserved.

Comparação de modelos para o cálculo de pertubações orbitais devidas à maré terrestre

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Performance de Trichogramma pretiosum Riley, 1879 e T. exiguum Pinto & Platner, 1978 (Hymenoptera: trichogrammatidae) em ovos de populações de Plutella xylostella (LINNAEUS, 1758) (Lepidoptera: Plutellidae) sob ação de Bacillus thuringiensis Berliner, 1915 (Bacillales: Bacillaceae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Da inquisição à ficção: as narrativas do inquérito e os processos da escrita em António Vieira e Lobo Antunes

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Os jesuítas e a escravidão africana no Brasil colonial: um estudo sobre os escritos de Antonio Vieira, André João Antonil e Jorge Benci: sécs. XVII e séc. XVIII

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Financiamiento del desarrollo económico: material para conferencias dictadas por el Sr. Aníbal Pinto Santa Cruz, Santiago, diciembre de 1959

Incluye Bibliografía

Relato e realidade nas cartas brasileiras do Padre Antônio Vieira: uma visão cognitivista e cultural

Pós-graduação em Linguística e Língua Portuguesa - FCLAR

Da ortografia para a fonética e a fonologia nos Sermões do Padre Antônio Vieira

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)