Correlação entre aneuploidia cromossômica em espermatozóides e taxa de implantação embrionária: subtitulo

Infertility is directly related to chromosomal abnormalities in germ cells. Among them, the aneuploidies are the most frequent chromosomal abnormalities and responsible for embryo implantation failures, miscarriages, fetal losses and newborns with congenital malformations, mental disability and neuropsychomotor developmental delay. Male patients with normal somatic karyotype may present different rates of aneuploidies in sperm, resulting in abnormal embryos. This study aimed to correlate the frequency of chromosomal aneuploidies in spermatozoa with embryo implantation rate in couples undergoing assisted reproductive techniques. The methodology has included chromosomal analysis by GTG banding and molecular cytogenetic study using Fluorescent In Situ Hybridization technique for evaluation of chromosomes 9, X and Y in germ cells of 22 patients referred to the Human Reproduction Service of the Clinical Hospital FMRP-USP. Embryo implantation rates were determined by hormonal evaluation in maternal peripheral blood and ultrasound confirmation. Two patients presented abnormal karyotype, characterized by polymorphism of the heterochromatic region of the long arm of chromosome 9 and a satellite in the short arm of chromosome 22. Both alterations, usually considered variants of normality, have been related to infertility phenotype and miscarriages. Significant differences were detected between couples who presented pregnancy (group 1) and couples with embryo implantation failure (group 2), with higher frequency of aneusomy and diploidy of chromosome 9, as well as total aneuploidy in sperm of group 2 patients. Our results suggest a correlation between aneuploidy and embryo implantation rates, since the infertile group with reproductive failure has showed higher frequency of aneuploidy. Screening for aneuploidies detection in male germ cells should be included in order to decrease embryo implantation failures, miscarriages and fetuses with chromosomal ...

Avaliação da influência da taxa de resfriamento posterior ao tratamento térmico nas propriedades mecânicas do aço API 5L X70

In this work a study about the mechanical properties of the API 5L X70 steel, with or without heat treating, has been made, with the intetion of assess the influence of cooling after the austenitization heat treating by air cooling (normalizing) and a rapid cooling with oil (tempering). This steel is known by high strength and ductility values and it is commonly used in the manufacture of oil pipes. The growing energy demand encouraged the study and manufacture of this material. Although this microalloyed dispense subsequent heat treatings, it was proven that its implementation is very advantageous for this type of application, improving hardness and plastic stability. It was also assessed that the faster the cooling rate is, the better will be these properties

Efeitos do exercício aeróbio prévio sobre a taxa de desenvolvimento de força em indivíduos ativos

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Competitividade internacional: uma análise dinâmica das exportações brasileiras frente à taxa de câmbio e aos estímulos governamentais no período recente

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Análise macro e micrográfica da liga AA-356 conforme a taxa de resfriamento

The present work aims to study the characteristics of the alloy Al - 7 % Si - 0 , 3Mg ( AA356 ) , more specifically characterize the macrostructure and microstructure and mechanical properties of the alloy ingots AA356 obtained in metal molds and sand molds for power studying the structures through the difference of cooling rates . This alloy is explained by the fact of referring league has excellent combination of properties such as low solidification shrinkage and good fluidity, good weldability , high wear resistance , high strength to weight ratio, has wide application in general engineering , and particularly in the automotive and aerospace engineering . In this work we will verify this difference in properties through two different cooling rates . We monitor the solid solidification temperatures by thermocouples building with them the cooling curve as a tool that will aid us to evaluate the effectiveness of the grain refining because it achieved with some important properties of the alloy as the latent heat of solidification fraction the liquid and solid temperatures, the total solidification time, and identify the presence of inoculants for grain refinement. Thermal analysis will be supported by the study of graphic software “Origin “will be achieved where the cooling curve and its first derivative that is the cooling rate. Made thermal analysis, analysis will be made in macrographs ingots obtained for observation of macrostructures obtained in both types of ingots and also analysis of micrographs where sampling will occur in strategic positions ingots to correlate with the microstructure. Finally will be collecting data from Brinell hardness of ingots and so then correlating the properties of their respective ingots with cooling rate. We found that obtained with cast metal ingots showed superior properties to the ingots obtained with sand mold

A influência do alongamento prévio no pico de torque e na taxa de desenvolvimento de força

The objective of this study was to investigate the influence of previous active static stretch on the peak torque (PT) and rate of force development (TDF) during isokinetic concentric contractions at 60 and 180.s-1 in active individuals. Twelve active subjects with ages between 18 and 30 years participated of this study. The individuals were submitted in different days to the following tests: 1) Familiarization session to the isokinetic dynamometer; 2) Five maximal isokinetic concentric contractions for knee extensors at each angular velocity (60 and 180.s-1) to determine PT and TDF (Control), and; 3) Two active static stretching exercises for the dominant leg extensors (10 x 30 s for each exercise, with 20 s of rest). After the stretching, the isokinetic test was repeated (Post-Stretching). The conditions 2 and 3 were performed in random order. There was no significant modification after the stretch exercises on the PT, angle and time at which the PT was attained, at 60 and 180º.s-1. In the same way, there was no significant modification on the TDF and angle at which the maximal TDF was attained in both angular speeds. In other way, the time to attain maximal TDF (TTDF) at 180º.s-1 was significantly lower after the stretching (Pre - 98.3 ± 27.5 ms and Post - 86.6 ± 30.2 ms). There was significant modification on the torque (60 and 180º.s-1) and time (60º.s-1) at different delta of angle variations, obtained at 60º.s-1 at Control and Post-Stretching conditions. However, there was significant reduction of time after the stretching exercises on delta of angle variations of 90-88º (Pre - 46.6 ± 6.5 ms and Post - 44.1 ± 5.1 ms), 88-85º (Pre - 65.8 ± 7.9 ms and Post - 63.3 ± 4.9 ms) and 85-80º (Pre - 93.3 ± 7.7 ms and Post - 90.0 ± 4.2 ms) at 180º.s-1. With base on these data, it is possible to conclude that PT and TDF do not modify after static stretching, irrespectively on the speed...(Complete abstract click electronic access below)

Avaliação da taxa de concepção de novilhas e vacas (Bos taurus x Bos indicus) com o uso de sêmen sexado na inseminação artificial ou embriões produzidos in vivo e in vitro

Pós-graduação em Medicina Veterinária - FCAV

Variação temporal e espacial da taxa de sedimentação e das características limnológicas na microbacia do córrego da Barrinha, no município de Pirassununga, SP

Studies regarding the quality and quantity of water have become more and more important because of the increasing negative environmental impacts occurred and their scarcity increase as well. At the Center of Tropical Fish Research (Centro de Pesquisas de Peixes Tropicais - CEPTAlIBAMA) located in the city of Pirassununga, SP, there is a dam named Represa Velha which supplies 128 tanks that are fish hatcheries. This dam takes in part of the Barrinha stream micro-basin where it has been observed strong impacts due to the deforestation of its support forest, as well an the intensive agricultural activities in the neighboring areas. There has been established and distributed 13 points of water-collectors disposed inside the stream and the dam. The water samples were taken from the stream only from its surface because of the low depth and, inside. In the dam, the water samples were taken at the water column, at a 50cm distance over the sediment. In every point of collection inside the dam, it was placed a chamber of sedimentation, vertically in the water column at a 70% height from the total depth. The collections took place during the dry/cold and raining/warm periods of the years 2000 and 2001. Then, it were analyzed the physical, physical-chemical, chemical and micro-biological parameters of the water samples. The obtained results were statistically analyzed throughout the SAS system (Statistical Analisys System). Parameters such as total phosphate, nitrate, nitrite and turbidity were within the established limits for the Class 2 water, according to the n° 20/1986 CONAMA Resolução. However, the total and Escherichia coli coliforms, mainly inside the Barrinha stream, had showed values above of the established limits for the same... (Complete abstract click electronic access below)

Aplicação de produtos fitossanitários na cultura dos citros utilizando pulverizador envolvente

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

Efeito da adição de CGTase e β-ciclodextrina na qualidade e taxa de envelhecimento de pães

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Incidência, fatores de risco e consequências de defeitos congênitos em recém-nascidos e natimortos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da Taxa de Exposição em Exames Radiológicos Realizados em Procedimentos Cirúrgicos - Minimização dos Riscos em Indivíduos Ocupacionalmente Expostos

This paper consists in the evaluation of the exposure rate to ionizing radiation to which professionals working in surgical procedures which require radiological examinations are subjected. Were initially performed real-time readings of exposure rate within four distinct operating rooms during the execution of four surgical procedures that made use of fluoroscopy equipment (including three orthopedic surgeries, one in the shoulder, one in the arm, another for deployment of metal pin in the leg region, and a fourth for vascular procedure); in these surgeries were used ionization chamber detector and an electrometer. In order to check the values achieved, was made a re-evaluation of the distribution of the rate of exposure to radiation, from the surgical procedures, now with thermoluminescent dosimeters (TLDs). For this, thirty TLDs were distributed in the operating rooms, arranged in points of interest as occupation by professionals. The TLDs were prepared for thirty consecutive days, after which they were removed and replaced with new dosimeters not exposed yet. The dosimeters were subjected to reading of the rate of exposure; this procedure was repeated for four months without interruption. The quantification of the results sought primarily to convert the rate of exposure for equivalent dose rate, both in measurements with ionization chamber as in measurements with TLDs, in order to highlight the presence of the biological effect of ionizing radiation for comparisons within scientific context. Then, the results were plotted to establish the relationship between the values of equivalent dose and the distance to the central axis of the x -ray source, confirming the inverse square law for distance. Finally, the values were associated with the maximum limit recommended by the legislation for occupationally exposed individuals. The methodology for the analysis and quantification of the data in this work aims at implementing a work plan that meets ...

Estudo do efeito do processo de shot peening na taxa de propagação de trinca por fadiga na liga aeronáutica 2024 - T3

Pós-graduação em Engenharia Mecânica - FEG

Fatores associados com a regressão da hipertrofia esquerda em diálise e impacto com mortalidade cardiovascular

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Bacillus subtilis na qualidade dos pintinhos ao nascer, desempenho e características intestinais dos frangos

Pós-graduação em Zootecnia - FCAV