Annales de l'Institut Pasteur.

t. 33 (1919)

Annales de l'Institut Pasteur.

t. 2 (1888)

Annales de l'Institut Pasteur.

t. 4 (1890)

Annales de l'Institut Pasteur.

t. 13 (1899)

Annales de l'Institut Pasteur.

t. 7 (1893)

Annales de l'Institut Pasteur.

t. 15, Index t.11-15

Annales de l'Institut Pasteur.

t. 14 (1900)

Annales de l'Institut Pasteur.

t. 32 (1918)

Annales de l'Institut Pasteur.

t. 11 (1897)

Annales de l'Institut Pasteur.

t. 16 (1902)

Annales de l'Institut Pasteur.

t. 3 (1889)

Annales de l'Institut Pasteur.

t. 5 (1891)

Annales de l'Institut Pasteur.

t. 12 (1898)

Prevalence of the metabolic syndrome in the Seychelles according to different definitions, contribution of components, and agreement between different definitions

Background: The metabolic syndrome (MS) represents a cluster of metabolic disorders that predicts diabetes and cardiovascular disease. Several definitions exist and further descriptive and prospective data are needed to compare these definitions and their significance in different populations. Objective: We examined, in a country of the African region, i) the prevalence of MS according to three major definitions (ATP, IDF, WHO); ii) the contribution of individual MS components; and iii) the agreement between the three considered definitions. We also examined the prevalence among diabetics and non-diabetics. Methods: We conducted an examination survey in a sample representative of the general population aged 25-64 of the Seychelles (Indian Ocean, African region), attended by 1255 persons (participation rate of 80.2%). Results: The prevalence of MS was similar with either definition of MS in men (24%--25%) but differed in women (WHO: 25%, ATP: 32%; IDF: 35%). Upon exclusion of diabetic persons, the prevalence was 5-10% lower for all three MS definitions: most diabetic persons had MS although a substantial proportion of diabetic men aged 45--64 did not have MS. The following components were found most often among persons with MS: 90% had high blood pressure (HBP) and 78% had obesity (ATP); 95% had obesity and 84% had HBP (WHO), and 89% had HBP and 75% had impaired glucose regulation (IDF) - not considering impaired glucose regulation and obesity that are compulsory components of the WHO and IDF definitions, respectively. Among persons with MS based on either of the three definitions (37% of total population), less than 80% met both ATP and IDF criteria, 67% both WHO and IDF criteria, 54% both WHO and ATP criteria and only 37% met all three definitions. Conclusion: We found a fairly high prevalence of MS in an African population. However, because there was only poor agreement between the 3 MS definitions, the fairly similar proportions of MS based on ATP, IDF or WHO definitions identified, to a substantial extent, different subjects as having MS.