Agreed-upon procedures report on the City of Armstrong, Iowa for the period October 1, 2013 through September 30, 2014

Agreed-upon procedures report on the City of Armstrong, Iowa for the period October 1, 2013 through September 30, 2014

Special investigation of the City of Garwin for the period January 1, 2001 through April 30, 2014

Special investigation of the City of Garwin for the period January 1, 2001 through April 30, 2014

Report on a special investigation of the Shenandoah Community School District for the period July 1, 2012 through September 30, 2014

Report on a special investigation of the Shenandoah Community School District for the period July 1, 2012 through September 30, 2014

Report on a special investigation of the City of Moorland for the period January 1, 2008 through October 31, 2013

Report on a special investigation of the City of Moorland for the period January 1, 2008 through October 31, 2013

Report on a special investigation of the West Des Moines Community School District - Western Hills Elementary School for the period May 22, 2012 through March 31, 2015

Report on a special investigation of the West Des Moines Community School District - Western Hills Elementary School for the period May 22, 2012 through March 31, 2015

Report on a review of the 8 Judicial Districts Department of Correctional Services for the period July 1, 2009 through June 30, 2014

Report on a review of the 8 Judicial Districts Department of Correctional Services for the period July 1, 2009 through June 30, 2014

Report on selected computer systems operated by the State of Iowa for the period July 1, 1999 through June 30, 2014

Report on selected computer systems operated by the State of Iowa for the period July 1, 1999 through June 30, 2014

Agreed-upon procedures report on the City of Hills, Iowa for the period October 1, 2013 through September 30, 2014

Agreed-upon procedures report on the City of Hills, Iowa for the period October 1, 2013 through September 30, 2014

Agreed-upon procedures report on the City of Kelley, Iowa for the period November 1, 2013 through October 31, 2014

Agreed-upon procedures report on the City of Kelley, Iowa for the period November 1, 2013 through October 31, 2014

Agreed-upon procedures report on the City of Tiffin, Iowa for the period July 1, 2013 through June 30, 2014

Agreed-upon procedures report on the City of Tiffin, Iowa for the period July 1, 2013 through June 30, 2014

Contribution of electrostatic interactions, compactness and quaternary structure to protein thermostability: lessons from structural genomics of Thermotoga maritima.

Studies of the structural basis of protein thermostability have produced a confusing picture. Small sets of proteins have been analyzed from a variety of thermophilic species, suggesting different structural features as responsible for protein thermostability. Taking advantage of the recent advances in structural genomics, we have compiled a relatively large protein structure dataset, which was constructed very carefully and selectively; that is, the dataset contains only experimentally determined structures of proteins from one specific organism, the hyperthermophilic bacterium Thermotoga maritima, and those of close homologs from mesophilic bacteria. In contrast to the conclusions of previous studies, our analyses show that oligomerization order, hydrogen bonds, and secondary structure play minor roles in adaptation to hyperthermophily in bacteria. On the other hand, the data exhibit very significant increases in the density of salt-bridges and in compactness for proteins from T.maritima. The latter effect can be measured by contact order or solvent accessibility, and network analysis shows a specific increase in highly connected residues in this thermophile. These features account for changes in 96% of the protein pairs studied. Our results provide a clear picture of protein thermostability in one species, and a framework for future studies of thermal adaptation.

Agreed-upon procedures report on the City of Breda, Iowa for the period December 1, 2013 through November 30, 2014

Agreed-upon procedures report on the City of Breda, Iowa for the period December 1, 2013 through November 30, 2014

Agreed-upon procedures report on the City of Randalia, Iowa for the period February 1, 2014 through January 31, 2015

Agreed-upon procedures report on the City of Randalia, Iowa for the period February 1, 2014 through January 31, 2015

Special investigation of the University of Iowa Health Care, Department of Orthopaedics and Rehabilitation, for the period July 1, 1999 through December 31, 2014

Special investigation of the University of Iowa Health Care, Department of Orthopaedics and Rehabilitation, for the period July 1, 1999 through December 31, 2014

Addendum to a report on a review of the Sixth Judicial District Department of Correctional Services for the period July 1, 2008 through June 30, 2014

Addendum to a report on a review of the Sixth Judicial District Department of Correctional Services for the period July 1, 2008 through June 30, 2014