Les moeurs des israélites ou l'on voit le modéle d'une Politique simple & sincère pour le gouvernement des Etats & de la réformation des moeurs /

Mode of access: Internet.

Maison Charrière : trouses nouveau modèle, avec instruments nouveaux /

Mode of access: Internet.

Maison Charrière : [trouses nouveau modèle, avec instruments nouveaux] /

Mode of access: Internet.

Maison Charrière : trouses nouveau modèle, avec instruments nouveaux /

Mode of access: Internet.

Maison Charrière : [nouveau modèle, avec instruments nouveaux] /

Mode of access: Internet.

Maison Charrière : [nouveau modèle, avec instruments nouveaux] /

Mode of access: Internet.

Traité de police municipale et rurale : résumant la législation et la jurisprudence de la Cour de Cassation sur la matière, et comprenant, sous la forme d'un réglement modèle, les dispositions les plus usuelles de police municipale et rurale /

Mode of access: Internet.

Maison Charrière : trouses nouveau modèle, avec instruments nouveaux /

Mode of access: Internet.

Manuel du pêcheur ou Traité général de toutes sortes de pêches : contenant l'histoire naturelle des poissons, la manière de pêcher chaque espèce en particulier, l'art de fabriquer les filets ; un traité sur les étangs, un précis des lois, ordonnances et réglements sur la pêche, un modèle des procès-verbaux qui doivent être dressés par les gardes-pêche, etc. /

Mode of access: Internet.

L'esprit de s. Vincent de Paul, ou, Modèle de conduite proposé a tous les ecclésiastiques, dans ses vertus, ses actions et ses paroles /

Signatures: a¹⁰ A-Y¹² Z².

L'Imitation de la très Sainte Vierge sur le modèle de l'Imitation de Jésus-Christ.

Mode of access: Internet.

The Collective Protagonist: Multiple Points of View and the Search for Truth in Familial Narratives

Thesis (Master's)--University of Washington, 2016-06

Universal Screening for Familial Colorectal Cancer Syndromes at Seattle Cancer Care Alliance: Qualitative Study of Providers involved in Implementation and Patients Experience with First Wave of Testing

Thesis (Master's)--University of Washington, 2016-06

Analysis of Melanoma Onset: Assessing Familial Aggregation by Using Estimating Equations and Fitting Variance Components via Bayesian Random Effects Models

We investigate whether relative contributions of genetic and shared environmental factors are associated with an increased risk in melanoma. Data from the Queensland Familial Melanoma Project comprising 15,907 subjects arising from 1912 families were analyzed to estimate the additive genetic, common and unique environmental contributions to variation in the age at onset of melanoma. Two complementary approaches for analyzing correlated time-to-onset family data were considered: the generalized estimating equations (GEE) method in which one can estimate relationship-specific dependence simultaneously with regression coefficients that describe the average population response to changing covariates; and a subject-specific Bayesian mixed model in which heterogeneity in regression parameters is explicitly modeled and the different components of variation may be estimated directly. The proportional hazards and Weibull models were utilized, as both produce natural frameworks for estimating relative risks while adjusting for simultaneous effects of other covariates. A simple Markov Chain Monte Carlo method for covariate imputation of missing data was used and the actual implementation of the Bayesian model was based on Gibbs sampling using the free ware package BUGS. In addition, we also used a Bayesian model to investigate the relative contribution of genetic and environmental effects on the expression of naevi and freckles, which are known risk factors for melanoma.

Expression and localization of mutant p16 proteins in melanocytic lesions from familial melanoma patients

Little is known about the correlation between the loss of p16 expression and tumor progression in familial melanoma; no systematic study has been conducted on p16 expression in melanocytic tumors from patients carrying germline CDKN2A mutations. We analyzed 98 early primary lesions from familial patients, previously tested for germline CDKN2A status, by quantitative immunohistochemistry using 3 p16 antibodies. We found that p16 expression was inversely correlated with tumor progression and was significantly lower in melanomas,. including in situ lesions, than in nevi. Of other features analyzed, tumor thickness showed the most significant correlation with p16 levels. Lesions from mutation-negative patients displayed combined nuclear and cytoplasmic staining. However, some mutation-positive lesions (ie, G101W, 113insR, M53I, R24P, and 33ins24), including benign nevi, showed nuclear mislocalization, confirming previous studies suggesting that subcellular distribution indicates functional impairment of p16. (C) 2004 Elsevier Inc. All rights reserved.