Bladder augmentation in rabbits with anionic collagen membrane, with or without urotelial preservation. Cistometric and hystologic evaluation

The use of bowel segments to perform bladder augmentation is associated with several metabolic and surgical complications. A great variety of synthetic materials, biodegradable or not, have been tested. Collagen-based biomaterials have shown effectiveness for the regeneration and obtainment of a functional bladder. Assess the functional and histological response of the rabbit bladder to anionic collagen membrane (ACM), either when it is anastomosed to the bladder or it is placed onto bladder after vesicomyectomy. In 15 male rabbit a partial cystectomy was performed. After 4 weeks they were divided in 3 groups. Group 1 (G1) - bladder augmentation with ACM. Group 2 (G2) ACM is placed onto bladder after vesicomyectomy. Group 3 (G3) control group. Maximal bladder capacity (MBC) and weight were assessed with 4 (M1), 8 (M2) and 12 (M3) weeks after partial cystectomy. In M3 was performed the sacrifice and extraction of the bladder and kidneys for anatomopathologic study. There were neither bladder stones, nor implant extrusion in M3. There was a significant increase in MBC in G1 and G2 (p<0.05), but no statistical differences in G3 (p=0.35). There is no significant difference comparing G1 and G2. In M3, both groups have shown a bigger MBC than G3 (p<0.05). The microscopic assessment showed an inflammatory reaction in the bladder augmented, with urothelium preserved. The ACM was effective for the increase of MBC. The bladders with preservation of the urothelium have shown an extensive inflammatory process.

Avaliação algimétrica por estímulo nociceptivo térmico e pressórico em cães pré-tratados com levomepromazina, midazolam e quetamina associados ou não ao butorfanol ou buprenorfina

This study aimed at quantifies the pain in dogs under dissociative anesthesia, across thermal and pressoric stimulus and quantify the reasonable period between two different opioids analgesics. In this study, 30 dogs were used and, divided into three groups of 10 animals each, in which the animals of GI received methotrimeprazine and midazolam put on the same syringe with ketamine. The animals of GII received the same treatment of GI but associated with butorphanol and finally the animals of GIII received the same treatment of GI but associated with buprenorphine. The routine parametric evaluations has been proceeded, although using the thermo algimetry measured in degrees C with the average of 52 degrees C and the pressoric algimetry in Kg. In the thermo algimetry, there has been significant difference in GI at the moments M0, M1, M4 and M5; in GII it was found at M0, M1, M5 and M6 and in GIII it was observed the significant at M0 and M1. It has also been shown in pressoric algimetry significant difference in GI at the moments M0, M2 and M3. Among GII it has observed significant difference at all moments and it has found at M0, M9 in GIII. Thus, it has observed significant differences between all groups; for such the M2 of GII smaller than the others; and M4, M5 of GIII bigger than GI and GII. In the assessment of all periods it was observed significant latent period bigger in GI, however, with reasonable period and short recovery in GII and GIII. In the order hand, the postural tonus recovery it was longer in GIII, followed by GII and finally GI. The used method for the measurement of algic stimulus was efficient, noticing a reasonable analgesic period of 3 hours for butorphanol and 6 hours for buprenorphine.

Peritoneal reactivity evaluation in horses subjected to experimental small colon enterotomy and treated with subcutaneous heparin

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Eferocitose na presença de PAMP estimula ativação de macrófagos de perfil misto M1/M2

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação das concentrações séricas de lactato, creatina quinase, aspartato aminotransferase, lactato desidrogenase, parâmetros clínicos e hematológicos de equinos Quarto de Milha submetidos à prova de laço em dupla

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estimativa da correção do coeficiente de retorno de esgoto sanitário em habitações com sistemas de aproveitamento de água pluvial: estudo de caso da cidade de Bauru (SP)

Pós-graduação em Engenharia Civil e Ambiental - FEB

Avaliação algimétrica por estímulo nociceptivo térmico e pressórico em cães pré-tratados com levomepromazina, midazolam e quetamina associados ou não ao butorfanol ou buprenorfina

This study aimed at quantifies the pain in dogs under dissociative anesthesia, across thermal and pressoric stimulus and quantify the reasonable period between two different opioids analgesics. In this study, 30 dogs were used and, divided into three groups of 10 animals each, in which the animals of GI received methotrimeprazine and midazolam put on the same syringe with ketamine. The animals of GII received the same treatment of GI but associated with butorphanol and finally the animals of GIII received the same treatment of GI but associated with buprenorphine. The routine parametric evaluations has been proceeded, although using the thermo algimetry measured in degrees C with the average of 52 degrees C and the pressoric algimetry in Kg. In the thermo algimetry, there has been significant difference in GI at the moments M0, M1, M4 and M5; in GII it was found at M0, M1, M5 and M6 and in GIII it was observed the significant at M0 and M1. It has also been shown in pressoric algimetry significant difference in GI at the moments M0, M2 and M3. Among GII it has observed significant difference at all moments and it has found at M0, M9 in GIII. Thus, it has observed significant differences between all groups; for such the M2 of GII smaller than the others; and M4, M5 of GIII bigger than GI and GII. In the assessment of all periods it was observed significant latent period bigger in GI, however, with reasonable period and short recovery in GII and GIII. In the order hand, the postural tonus recovery it was longer in GIII, followed by GII and finally GI. The used method for the measurement of algic stimulus was efficient, noticing a reasonable analgesic period of 3 hours for butorphanol and 6 hours for buprenorphine.

Variações diurnas da temperatura corporal, proteínas plasmáticas e eritrograma de cabras não prenhes

Hemogram values may have variations caused by intrinsic or extrinsic factors, which can take healthy animals to present values outside of the normal reference ranges and it is important to the veterinarian to know these variation factors for a correct results interpretation. The influence of the period of the day is among them. The objective of this study was to test the hypothesis that there are hematological parameters variations, such as erythrogram and plasmatic proteins during the day. The study was carried out with 10 non-pregnant adult goats in Araçatuba/SP/Brazil. The blood sampling and physical exam occurred at three moments between 07:00 and 08:00 a.m. (M1), 12:30 and 01:30 p.m. (M2), 5:00 and 6:00 p.m. (M3). We noted differences in the values of packed cell volume (PCV), hemoglobin, and rectal temperature through the moments, with reduction of PCV and hemoglobin were related to increase in rectal and air temperature, leading to water intake increase and, consequently, decreasing blood concentration. These variations could lead to an error of interpretation of the results due to values below the reference ranges.

Influência do butorfanol sobre os períodos de latência e de ação da ropivacaína pela via peridural na ovariossalpingo-histerectomia em cadelas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeitos agudos do exercício resistido, aeróbio contínuo e intervalado na pressão intraocular de indivíduos fisicamente ativos e normotensos

Apesar de pouco explorado, a prática de atividade física promove redução da Pressão Intraocular (PIO). O objetivo foi verificar o efeito de diferentes tipos de exercício na PIO. Quinze voluntários foram submetidos a 3 sessões de 30min de exercícios resistidos (3 x 8 repetições a 80%1RM), aeróbio contínuo (60% da Frequência Cardíaca de Reserva [FCR]), aeróbio intervalado (2min a 50% alternando com 1min a 80% da FCR). PIO foi mensurada antes (M1), durante (M2-15min), imediatamente após a sessão (M3) e na recuperação (5min [R1] e 10min [R2]). Como procedimento estatístico foi utilizado ANOVA. Houve redução da PIO nas 3 sessões de exercício (M2 e M3). Na recuperação, PIO permaneceu reduzida após 5min (R1) em todos os modelos. Porém, aos 10min (R2) estava menor que M1 apenas na sessão de exercício intervalado. Os resultados sugerem que o exercício intervalado é mais efetivo que o contínuo e resistido na redução da PIO.

Efeito agudo do exercício resistido, aeróbio contínuo e intervalado na pressão intraocular de indivíduos fisicamente ativos

Estudos sugerem que a atividade física promove redução e contribui no controle da Pressão Intraocular (PIO). O objetivo foi verificar o efeito de diferentes exercícios na PIO. Quinze voluntários foram submetidos a 3 sessões de 30min de exercícios resistidos (3 x 8 repetições a 80%1RM), aeróbio contínuo (60% da Frequência Cardíaca de Reserva [FCR]), aeróbio intervalado (2min a 50% alternando com 1min a 80% da FCR). PIO foi mensurada antes (M1), durante (M2-15min), imediatamente após a sessão (M3) e na recuperação (5min [R1] e 10min [R2]). Adotou-se ANOVA para tratamento estatístico. Houve redução significativa da PIO nas 3 sessões de exercício (M2 e M3). Na recuperação, PIO permaneceu reduzida após 5min (R1) em todos os modelos. Porém, aos 10min (R2) estava menor que M1 apenas na sessão de exercício intervalado. Os resultados sugerem que o exercício intervalado pode ser mais efetivo que o contínuo e resistido na diminuição da PIO.

Caracterização biofísica da interação entre a proteína M2-1 do Vírus Sincicial Respiratório Humano (HRSV) com quercetina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação convencional e estesiômetro: resultados controversos na avaliação sensitiva no câncer de mama

This study, clinical, prospective, randomized study was conducted from August 2004 to February 2008 in a convenience sample of 60 women who underwent breast surgery with axillary dissection, divided into two groups (n = 30). The GI (Guidance Kit with different textures, to perform at home) and GII (control). The objective was to analyze the effect of home orientation in patients after surgery for breast cancer complaining of numbness, evaluation, and the conventional esthesiometer. The surface sensitivity was assessed by monofilament Semmes-Weinstein and evaluation using conventional two test tubes with hot water (38 to 43o C) and cold (16 to 27o C), paintbrush, needle. The GI was subjected to 10 sessions and assessments in both 3 times. The M1 (pre intervention), the M2 (post-intervention) after 10 sessions of physical therapy intervention and M3 (washout) after 3 months the second time for assessment. The region targeted for evaluation and intervention was the sensory nerve dermatome intercostobrachial. In the test of Goodman (conventional assessment) there was improvement in both groups, the P1, during the thermal evaluation. The t-test of student (esthesiometer) there was improvement in P2 only in GI (p = 0.003) between points 1 and 2 while the time 3 (p = 0.121 and p = 0.733 respectively). It was concluded that there were divergent and opposite results after examining the effect of home orientation in the nerve dermatome intercostobrachial, evaluation, and the conventional esthesiometer.

Recria de Rã touro (Rana catesbeiana) em tanques-rede alojados em viveiros de tilápia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)