Population and Government in Colonial Buenos Aires. An Approach to the Study of the Tensions Generated by Demographic Growth in the City (1740-1776)

The relationship between population and government in the City of Buenos Aires is analyzed, focusing on the tensions generated by the arrival of new individuals, a local elite with great interests in commerce and in charge of community affairs, and Spanish functionaries that progressively adopted the ideals of the Bourbon Dynasty, despite also being implicated in local logics. It interests us to observe the governors’ perspectives with respect to everyday developments in the city, their preoccupations and interests, and how they would vary the mechanisms to which they resorted in order to organize daily life, in the period defined between 1740 and 1776.

Dossier “Império Português e Comunicações"

A relação entre as comunicações, os media e o império português é o tema principal do dossiê que se propõe. O volume tem uma base interdisciplinar, acolhendo estudos de comunicação, história, literatura, entre outros domínios dos estudos humanísticos e das ciências sociais, que contribuam para a melhor compreensão das relações entre as comunicações e a política imperial de Portugal desde o século XVIII até finais da década de 1970. A partir de uma perspectiva alargada de comunicação, que pode abranger as estruturas físicas de transporte e todas as formas de comunicação simbólica (correio, imprensa, mass media, literatura, arquitetura, iconografia, etc), encoraja-se a apresentação de estudos que esclareçam as articulações e tensões entre os mais diversos media e o estabelecimento e manutenção de um império português no Brasil, em Angola, Moçambique, São Tomé e Príncipe, Cabo Verde, Guiné-Bissau, India (Goa, Damão e Diu), Timor-Leste e Macau. Procuram-se pesquisas que privilegiem uma multiplicidade de perspectivas da metrópole e das colônias e que enfatizem as interações entre comunicação, política, economia, sociedade e identidades culturais e nacionais. Aceitam-se contribuições em tópicos como: Conjugações e conexões entre transportes e comunicação na dinâmica imperial; Relação entre missões exploratórias, cartografia, infraestruturas de comunicação e estabelecimento de um Império; Media e comemoracionismo; Imprensa, propaganda, opinião pública e domínio imperial; Imperialismo e cultura popular; Meios de comunicação nas colónias (imprensa, rádio, literatura), resistência e constituição de identidades nacionais.

Analyse du rôle de l'IFREMER dans l'instruction du dossier Salmor

This report describes the contribution made by IFREMER in the various stages of installation of a new salmon culture in barge's tanks moored in Morlaix Bay. Tacking into account the opposition to this project, including direct criticism of the role of IFREMER, a considerable effort is made to provide detailed environmental impact data to the appropriate Government office

La contrebande à Montréal, 1729-1752 : passages, pratiques et protagonistes

Les commerces de contrebande fascinent, que ce soit par leurs structures occultes ou les acteurs impliqués dans les activités économiques illégales. C’est évidemment un thème très peu exploité dans l’historiographie de la Nouvelle-France étant donné la difficulté d’obtenir des informations : les acteurs n’ont pas intérêt à laisser des traces de leur implication dans des activités illégales que les autorités coloniales tentent de faire cesser ou du moins de réduire. Force est de constater que les femmes ne sont pas en reste. Elles sont parties intégrantes des différentes étapes que doivent suivre les marchandises illégales dont font commerce les contrebandiers de Montréal. Les différents documents d’archives consultés permettent toutefois d’avoir assez d’informations pour saisir les structures du commerce illégal en place à Montréal ainsi que les façons de faire de la contrebande prisées par les marchands illégaux. Après avoir fait un tour d’horizon de l’histoire économique du XVIIIe siècle en Nouvelle-France, nous nous sommes penché sur un document d’archive particulier, le journal de Catherine Dagneau; elle informe les autorités de ce qu’elle voit et de ce qui lui est rapporté par des tierces personnes, grâce à son statut singulier de veuve d’un ancien interprète des Amérindiens. Finalement, il nous semblait impossible de faire une étude sur les commerces de contrebande sans parler du cas unique et reconnu des sœurs Trottier-Desauniers, dont il sera question en dernier lieu. Quoiqu’il en soit, étudier la contrebande en Nouvelle-France, c’est réaliser une enquête sur un pan important de la vie économique de la colonie. C’est s’attaquer à ce que les acteurs de ces activités souhaitaient garder caché. C’est comprendre la nature et le fonctionnement de la société coloniale par la mise en place de structures économiques précises.

Dossier teórico sobre desarrollo rural

Estrategias de desarrollo rural en la UE: definición de espacio rural, ruralidad y desarrollo rural.

Arquitectura d'Elx. Dossier per a la salvació del patrimoni arquitectònic

Arquitectura d'Elx. Dossier per a la salvació del patrimoni arquitectònic, catàleg de l'exposició homònima, Elx, Caja de Ahorros de Alicante y Murcia, 1978.

Motor Nerve-Conduction Studies in Obstetric Brachial Plexopathy for a Selection of Patients with a Poor Outcome

Background: The criteria and timing for nerve surgery in infants with obstetric brachial plexopathy remain controversial. Our aim was to develop a new method for early prognostic assessment to assist this decision process. Methods: Fifty-four patients with unilateral obstetric brachial plexopathy who were ten to sixty days old underwent bilateral motor-nerve-conduction studies of the axillary, musculocutaneous, proximal radial, distal radial, median, and ulnar nerves. The ratio between the amplitude of the compound muscle action potential of the affected limb and that of the healthy side was called the axonal viability index. The patients were followed and classified in three groups according to the clinical outcome. We analyzed the receiver operating characteristic curve of each index to define the best cutoff point to detect patients with a poor recovery. Results: The best cutoff points on the axonal viability index for each nerve (and its sensitivity and specificity) were <10% (88% and 89%, respectively) for the axillary nerve, 0% (88% and 73%) for the musculocutaneous nerve, <20% (82% and 97%) for the proximal radial nerve, <50% (82% and 97%) for the distal radial nerve, and <50% (59% and 97%) for the ulnar nerve. The indices from the proximal radial, distal radial, and ulnar nerves had better specificities compared with the most frequently used clinical criterion: absence of biceps function at three months of age. Conclusions: The axonal viability index yields an earlier and more specific prognostic estimation of obstetric brachial plexopathy than does the clinical criterion of biceps function, and we believe it may be useful in determining surgical indications in these patients.

Phytoseiid mites (Acari : Phytoseiidae) of the subfamilies Phytoseiinae Berlese and Typhlodrominae Wainstein from Peru, with descriptions of two new species

This paper reports the mites of the subfamilies Phytoseiinae and Typhlodrominae (Phytoseiidae) from Peru, providing descriptions of 2 new species, Phytoseius ortegae Guanilo and Moraes, n. sp. and Phytoseius poripherus Guanilo and Moraes, n. sp., and a taxonomic key to separate the species reported.

Out of the Andes: patterns of diversification in clearwing butterflies

Global biodiversity peaks in the tropical forests of the Andes, a striking geological feature that has likely been instrumental in generating biodiversity by providing opportunities for both vicariant and ecological speciation. However, the role of these mountains in the diversification of insects, which dominate biodiversity, has been poorly explored using phylogenetic methods. Here we study the role of the Andes in the evolution of a diverse Neotropical insect group, the clearwing butterflies. We used dated species-level phylogenies to investigate the time course of speciation and to infer ancestral elevation ranges for two diverse genera. We show that both genera likely originated at middle elevations in the Andes in the Middle Miocene, contrasting with most published results in vertebrates that point to a lowland origin. Although we detected a signature of vicariance caused by the uplift of the Andes at the Miocene-Pliocene boundary, most sister species were parapatric without any obvious vicariant barrier. Combined with an overall decelerating speciation rate, these results suggest an important role for ecological speciation and adaptive radiation, rather than simple vicariance.

Population pharmacokinetics and pharmacodynamics: An underutilized resource

A meeting was convened in Canberra, Australia, at the request of the Australian Drug Evaluation Committee (ADEC), on December 3-4, 1997 to discuss the role of population pharmacokinetics and pharmacodynamics in drug evaluation and development. The ADEC was particularly concerned about registration of drugs in the pediatric age group. The population approach could be used more often than is currently the case in pharmacokinetic and pharmacodynamic studies to provide valuable information for the safe and effective use of drugs in neonates, infants, and children. The meeting ultimately broadened to include discussion about other subgroups. The main conclusions of the meeting were: 1. The population approach, pharmacokinetic and pharmacodynamic analysis, is a valuable tool both for drug registration purposes and for optimal dosing of drugs in specific groups of patients, 2. Population pharmacokinetic and pharmacodynamic studies are able to fill in the gaps' in registration of drugs, for example, to provide information on optimal pediatric dosing. Such studies provide a basis for enhancing product information to improve rational prescribing, 3. Expertise is required to perform the population studies and expertise, with a clinical perspective, is also required to evaluate such studies if they are to be submitted as part of a drug registration dossier Such expertise is available in the Australasian region and is increasing. Centers of excellence with the appropriate expertise to advise and assist should be encouraged to develop and grow in the region, 4. The use of the population approach by the pharmaceutical industry needs to be encouraged to provide valuable information not obtainable by other techniques. The acceptance of population pharmacokinetic and pharmacodynamic analyses by regulatory agencies also needs to be encouraged, and 5. Development of the population approach to pharmacokinetics and pharmacodynamics is needed from a public health perspective to ensure that all available information is collected and used to improve the way drugs are used. This important endeavor needs funding and support at the local and international levels.

A single dose of zoledronic acid reverses the deleterious effects of glucocorticoids on titanium implant osseointegration

This study evaluates the effect of zoledronic acid (ZOL) on the osseointegration of titanium implants in rabbits with glucocorticoid (GC)-induced bone loss, and our findings demonstrated that a single dose of ZOL is able to reverse the detrimental effects of GCs on the osseointegration of titanium implants. The purpose of this study is to evaluate the effect of ZOL on the osseointegration of titanium implants in rabbits with GC-induced bone loss. Three groups of six NZW rabbits were treated for 18 weeks with saline (SALINE), GC (methylprednisolone, 0.35 mg/kg three times a week), or GC + ZOL (methylprednisolone + single dose of ZOL, 0.1 mg/kg). The animals received a titanium implant in the left tibia after 6 weeks and were killed at the 18th week. Bone mineral density (BMD) was measured with dual-energy X-ray absorptiometry at baseline, eighth week (W8), and 18th week (W18) after treatment to determine the change upon treatment (a dagger BMD). Histomorphometric and serum bone alkaline phosphatase analysis (BAP) were also performed. At W8, GC group had a significant reduction in lumbar spine and tibia BMD compared with SALINE (p = 0.003 and p = 0.000), as also observed for GC + ZOL group (p = 0.014 and p = 0.003) just 2 weeks after ZOL treatment. In contrast, at W18, the GC + ZOL had an evident BMD rescue with similar lumbar spine and tibia a dagger BMD compared with SALINE (0.043 +/- 0.006 vs. 0.055 +/- 0.009 g/cm(2), p = 0.457 and 0.027 +/- 0.003 vs. 0.041 +/- 0.011 g/cm(2), p = 0.232) and a significantly higher a dagger BMD compared with the GC (p = 0.024 and p = 0.001). Histomorphometry revealed that osseointegration was significantly reduced in GC (tibia cortical thickness and diameter, bone-implant contact, total and peri-implant bone area) whereas GC + ZOL had these parameters similar to SALINE (p > 0.05). Likewise, ZOL reversed the BAP alteration induced by GC. Our findings demonstrated that a single dose of ZOL is able to reverse the detrimental effects of glucocorticoids on the osseointegration of titanium implants, suggesting that ZOL therapy may improve the outcome of bone implants in patients with glucocorticoid-induced osteoporosis.

Coaching no setor p??blico: a aplica????o na carreira de Especialista em Pol??ticas P??blicas e Gest??o Governamental no Brasil ?? luz da p??tica no governo federal dos Estados Unidos da Am??rica

O presente trabalho constitui ?? um estudo da aplica????o da metodologia coaching no governo federal brasileiro, a partir da an??lise da proposta de carreira de Especialista em Pol??ticas P??blicas e Gest??o Governamental (EPPGG). A Reforma do Estado conduzida durante a d??cada de 1990 foi um marco de mudan??as significativas para quest??es relativas aos recursos humanos no setor p??blico brasileiro, promovendo a????es direcionadas ?? implanta????o de uma administra????o p??blica gerencial no pa??s. No entanto, restaram lacunas que devem ser preenchidas, de forma que os recursos humanos sob a gest??o p??blica sejam pass??veis possam de adapta????o ??s mudan??as e aquisi????o de compet??ncias para uma atua????o flex??vel e eficiente. O coaching surge como uma metodologia que busca auxiliar os l??deres no governo federal brasileiro a alcan??ar melhores indicadores de forma????o e produtividade dos recursos humanos no setor p??blico em n??vel federal. Analisaram-se comparativamente os par??metros da proposta de coaching descritos na carreira de EPPGG e as aplica????es realizadas no governo federal dos Estados Unidos da Am??rica.