977 resultados para Energetics quantities


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Diplomityössä tutkitaan tuotannonohjausmuodon vaihtamista tilausohjautuvasta varasto-ohjautuvaan. Tavoitteena on löytää kohdeyritykselle kustannustehokkain vaihtoehto tuotannonohjaukseen. Tutkimuksessa analysoidaan yrityksen tuotantoprosessi nykytila-analyysilla toiminnan tehokkuuden arvioimiseksi ja tuotannon pullonkaulojen löytämiseksi. Asiakastilauksen kytkentäpisteet ja taloudelliset tuotantoeräkoot määritellään yrityksen valmistamille tuotteille. Työn tuloksissa käydään tuotannon tunnuslukujen avulla läpi tuotannon tehokkuuden kehittymistä projektin aikana. Varasto-ohjautuva tuotannonohjausmuoto osoittautui kannattavimmaksi ohjausmuodoksi tarkasteltavana ajankohtana. Toimitusvarmuus ja kapasiteetin käyttöaste parantuivat ohjausmuodon vaihtamisen myötä. Asetuskustannuksia saatiin vähennettyä ja tuotantoprosessia kehitettyä. Tuotannon läpimenoaikojen lyhennyttyä tilausohjautuvuutta tulee tarkastella uudestaan.

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Työn tavoitteena oli selvittää, miten elintarviketukun suurtaloustuotteiden saatavuus voitaisiin varmistaa. Nykyisellään suurtalouselintarvikkeiden kysynnän vaihtelut ovat vaikeasti hallittavia, mikä nostaa niiden varastotasoja aiheuttaen ongelmia kohdeyrityksen ahtaaksi käyneessä varastossa. Lisäksi tuotteiden tilaaminen työllistää neljä henkilöä ja mahdollinen tilausmäärien kasvu lisäisi henkilöstötarvetta entisestään. Työn tuloksena yrityksen tuotteet sekä toimittajat jaettiin neljään eri ryhmään: paras a-ryhmä, haasteryhmä, testiryhmä ja poistoryhmä. Näiden ryhmien varastojen ja tilausten hallitsemiseksi esitettiin puolestaan kolme eri tapaa: Automaattiset ostotilaukset sopivat kaikille tasaisen kysynnän tuotteille. Suuren kysynnän vaihtelun tuotteille voidaan käyttää nykyistä tilaustapaa sekä hyödyntää mahdollisuuksien mukaan asiakkailta saatavia menekkiennusteita tilaamisen tukena. Ongelmallisten suuren kysynnän vaihtelun ja pienen menekin tuotteiden kohdalla tuot-teet voidaan joko poistaa kokonaan yrityksen valikoimasta tai niiden tilaaminen voidaan muuttaa varasto-ohjauksen sijaan tilausohjautuvaksi.

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The objective of this review on the investigation of "cara inchada" in cattle (CI), pursued over the last 30 years, was to elucidate the pathogenicity of the disease and come to proper conclusions on its etiology. CI has been widely considered to be of nutritional origin, caused primarily by mineral deficiency or imbalance. However, the disease consists of a rapidly progressive periodontitis, affecting the periodontal tissues at the level of the premolars and molars during the period of tooth eruption generally starting in young calves. The disease led to great economic losses for farmers in central-western Brazil, after the occupation of new land for cattle raising in the 1960s and 1970s. The lateral enlargement of the maxillary bones of affected calves gave the disease the popular name of "cara inchada", i.e., swollen or enlarged face. The enlargement was found to be due to a chronic ossifying periostitis resulting from the purulent alveolitis of CI. Black-pigmented non-saccharolytic Bacteroides melaninogenicus, always together with Actinomyces (Corynebacterium) pyogenes, were isolated in large numbers from the periodontal lesions. B. melaninogenicus could be isolated in small numbers also from the marginal gingiva of a few healthy calves maintained on CI-free farms. "In vitro"-assays showed that streptomycin and actinomycin, as well as the supernatants of cultivates of actinomycetes from soils of CI-prone farms, applied in subinhibitory concentrations to the bacteria tested, enhanced significantly (up to 10 times) the adherence of the black-pigmented B.melaninogenicus to epithelial cells of the bovine gingiva. The antibiotics are apparently produced in large quantities by the increased number of soil actinomycetes, including the genus Streptomyces, that develop when soil microflora are modified by cultivating virgin forest or "Cerrado" (tree-savanna) for the first time for cattle grazing. The epidemiology of CI now provides strong evidence that the ingestion with the forage of such antibiotics could possibly be an important determinant factor for the onset and development of this infectious periodontitis. The antibiotic enhanced adherence of B.melaninogenicus to the sulcus-epithelium of the marginal gingiva, is thought to allow it to colonize, form a plaque and become pathogenic. There is experimental evidence that this determinant factor for the development of the periodontitis is present also in the milk of the mothers of CI-diseased calves. It has been shown that the bacteria isolated from the periodontal CI-lesions produce enzymes and endotoxins capable of destroying the periodontal tissues. The epidemiology of CI, with its decline in incidence and its disappearance after several years, could be explained by the fact that the former equilibrium of the microflora of the once undisturbed virgin soil has been reached again and that the number of antibiotic producing actinomycetes has been anew reduced. By this reasoning and all the data available, CI should be considered as a multifactorial infectious disease, caused primarily by the anaerobic black-pigmented non-saccharolytic Bacteroides melaninogenicus, always together with the micro-anaerobic Actinomyces pyogenes. Accordingly, the onset and development of the infectious periodontitis is apparently determined by ingestion with the forage of subinhibitory concentrations of antibiotics produced in recently cultivated virgin soils. This hypothesis is supported by the recent observation of renewed outbreaks of CI-periodontitis in former CI-prone areas, following fresh cultivation after many years. The infectious nature of CI is confirmed by trials in which virginiamycin was used efficiently for the oral treatment of CI-diseased cattle. Previously it has been shown, that spiramycin and virginiamycin, used as additives in mineral supplements, prevented CI-periodontitis.

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Oxidized starch is a key component in the paper industry, where it is used as both surfacing sizer and filler. Large quantities are annually used for this purpose; however, the methods for the oxidation are not environmentally friendly. In our research, we have studied the possibility to replace the harmful oxidation agents, such as hypochlorite or iodates and transition metal catalysts, with a more environmentally friendly oxidant, hydrogen peroxide (H2O2), and a special metal complex catalyst (FePcS), of which only a small amount is needed. The work comprised batch and semi-batch studies by H2O2, ultrasound studies of starch particles, determination of low-molecular by-products and determination of the decomposition kinetics of H2O2 in the presence of starch and the catalyst. This resulted in a waste-free oxidation method, which only produces water and oxygen as side products. The starch oxidation was studied in both semi-batch and batch modes in respective to the oxidant (H2O2) addition. The semi-batch mode proved to yield a sufficient degree of substitution (COOH groups) for industrial purposes. Treatment of starch granules by ultrasound was found to improve the reactivity of starch. The kinetic results were found out to have a rather complex pattern – several oxidation phases were observed, apparently due to the fact that the oxidation reaction in the beginning only took place on the surface, whereas after a prolonged reaction time, partial degradation of the solid starch granules allowed further reaction in the interior parts. Batch-mode experiments enabled a more detailed study of the mechanisms of starch in the presence of H2O2 and the catalyst, but yielded less oxidized starch due to rapid decomposition of H2O2 due to its high concentrations. The effect of the solid-liquid (S/L) ratio in the reaction system was studied in batch experiments. These studies revealed that the presence of the catalyst and the starch enhance the H2O2 decomposition.

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Transportation of fluids is one of the most common and energy intensive processes in the industrial and HVAC sectors. Pumping systems are frequently subject to engineering malpractice when dimensioned, which can lead to poor operational efficiency. Moreover, pump monitoring requires dedicated measuring equipment, which imply costly investments. Inefficient pump operation and improper maintenance can increase energy costs substantially and even lead to pump failure. A centrifugal pump is commonly driven by an induction motor. Driving the induction motor with a frequency converter can diminish energy consumption in pump drives and provide better control of a process. In addition, induction machine signals can also be estimated by modern frequency converters, dispensing with the use of sensors. If the estimates are accurate enough, a pump can be modelled and integrated into the frequency converter control scheme. This can open the possibility of joint motor and pump monitoring and diagnostics, thereby allowing the detection of reliability-reducing operating states that can lead to additional maintenance costs. The goal of this work is to study the accuracy of rotational speed, torque and shaft power estimates calculated by a frequency converter. Laboratory tests were performed in order to observe estimate behaviour in both steady-state and transient operation. An induction machine driven by a vector-controlled frequency converter, coupled with another induction machine acting as load was used in the tests. The estimated quantities were obtained through the frequency converter’s Trend Recorder software. A high-precision, HBM T12 torque-speed transducer was used to measure the actual values of the aforementioned variables. The effect of the flux optimization energy saving feature on the estimate quality was also studied. A processing function was developed in MATLAB for comparison of the obtained data. The obtained results confirm the suitability of this particular converter to provide accurate enough estimates for pumping applications.

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Our objective was to evaluate the diagnosis of swine cysticercosis by examining "ante mortem" (inspection of the tongue), "post mortem" (inspection and detailed necropsy) and ELISA for research in serum of antibodies (Ab-ELISA) and antigens (Ag-ELISA). Seven (7) pigs were experimentally infected orally with eggs of Taenia solium and another 10 were naturally infected. In the pigs experimentally infected, inspection of the tongue was negative in all animals, in the routine inspection detailed necropsy and cysticercis were identified in all of them. In pigs with heavy natural infection, inspection of the tongue identified cysticerci in two (20%), while at inspection with necropsy the parasites were identified in large quantities in all animals. In ELISA for antibody search (Ab-ELISA) TS-14 recombinant protein was used, and in search for antigen (Ag-ELISA) a monoclonal antibody against this protein. In animals experimentally infected, blood was collected weekly for 140 days. The Ab-ELISA identified an increase in titers of antibody to cysticerci 21 days after infection, and at the end of the experimental period six animals (86%) were positive to the test. The search for circulating antigens (Ag-ELISA) was positive in two pigs 28 to 91 days after infection. All naturally infected pigs were positive for Ag-ELISA and Ab-ELISA. The search for antibodies and antigens by ELISA in serum from 30 pigs of a local farm and without history of cysticercosis was negative. Thus, the use of TS-14 antigen in ELISA test (Ab-ELISA) can be useful for the diagnosis of cysticercosis in pigs with low infection.

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Tässä työssä tutkittiin sähkön käyttömahdollisuuksia metsäteollisuuden jäteveden-puhdistamolla syntyvän biolietteen kuivauksessa. Lisäksi selvityksen kohteena olivat lietteen sähkökuivaukseen vaikuttavat tekijät. Työn kirjallisessa osassa perehdyttiin lietteiden syntyyn jätevedenpuhdistamolla sekä lietteiden ominaisuuksiin. Työssä tutustuttiin myös lietteiden käsittelyyn ja siinä käytettäviin tekniikoihin. Ennen työn kokeellista osaa esiteltiin sähkökuivauksen periaate sekä sähkökuivaukselle aiemmin tehtyjä tutkimuksia ja niistä saatuja kokemuksia. Myös tuotteistetut elektrokuivauksen sovellukset olivat osa työtä. Kokeellisessa osassa keskityttiin varsinaisiin sähkökuivauskokeisiin. Tutkimukset suoritettiin suodatuskokein, jotka toteutettiin imuun perustuvalla Büchner-suodattimella sekä painesuodattimella. Kokeissa tutkittiin tasavirran, virran pulssituksen ja vaihtovirran vaikutusta metsäteollisuuden primääri- ja biolietteeseen. Tasavirtatutkimuksissa sähkövirtaa johdettiin lietteeseen suodatuksen aikana, kun taas vaihtovirtaa testattaessa liete käsiteltiin ensin sähköllä ja suodatettiin erikseen. Suodatuskokeiden lisäksi tutkimuksissa tarkkailtiin lietteiden kuiva-ainepitoisuuksia, redox-potentiaalia, lämpötilaa, pH:ta ja sähkönjohtokykyä. Lietteitä tutkittiin myös tuhkapitoisuuden suhteen sekä suoritettiin solututkimuksia fluoresenssilukijan avulla. Työn laboratoriotutkimukset osoittivat sähkön vaikuttavan selkeästi biolietteen ve-denerotuskykyyn: sähkö nopeutti lietteen suodatusta parhaimmillaan yli 70 %. Säh-kökuivauksella lietteen kuiva-ainepitoisuudet pysyivät samoina, mutta suodatus nopeutui ja suodatusajat jopa puolittuivat. Myös lietteen sähkönjohtokyky kasvoi sähkökäsittelyn aikana, mikä viittasi veden vapautumiseen solujen sisältä. Lietteen kunto ja ominaisuudet, polymeeri, sekoitus sekä sähkökäsittelyn parametrit olivat tärkeässä asemassa sähkökuivauksen onnistumisen kannalta.

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The paper addresses the epidemiologic data of the death of pigs during the period of 2002 to 2009 following the ingestion of botulinum neurotoxin type C. This neurotoxin was present in food residues originating from restaurant and hotel kitchens, stored in barrels without shelter from the sun and administered in a collective trough without prior thermal treatment. Animals which died at different ages showed clinical signs of botulism characterized by flaccid paralysis, weight loss, anorexia, weakness, lack of coordination, locomotion difficulties with the evolution of lateral recumbency with involuntary urination and defecation. No alterations were observed at postmortem and histological examination. The bioassay with serum neutralization in mice was carried out on samples of intestinal contents from pigs affected and revealed the presence of large quantities of botulinum toxin type C.

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Paremmin lastuttavia M-käsiteltyjä teräksiä on käytetty yrityksissä jo yli 20 vuoden ajan. Ominaisuuksiensa ansiosta M-teräksillä on pystytty pienentämään koneistuskustannuksia ja parantamaan kilpailukykyä. Viime vuosien aikana lastuavat terät ja työstökoneet ovat kuitenkin kehittyneet ja ero M-terästen ja tavanomaisten terästen välillä on voinut kaventua. Tämän diplomityön tavoitteena oli tutkia, saavutetaanko M-teräksen käytöllä taloudellisia etuja nykyaikaisissa konepajaolosuhteissa. Tutkimuksessa vertailtiin M-käsitellyn ja tavanomaisen 42CrMo4 – teräksen koneistusta. Valmistuskokeissa tarkasteltiin terien kulumista, lastun muotoa ja pinnanlaatua. Koekappaleena toimi olakkeellinen kuusiomutteri M64 kierteellä. Tuotteita valmistettiin yli 500 kappaletta ja materiaalia poistettiin noin 2000 kg. Koetulosten perusteella tuotteille laskettiin koneistuskustannukset kuvitteellisessa yrityksessä. Ero materiaalien välillä oli suurin työvaiheissa, joissa lastuaminen oli jatkuvaa. Sisä- ja ulkosorvauksessa M-käsiteltyä terästä lastunneiden terien kestoikä oli noin kaksinkertainen ja kierteen sorvauksessa noin nelinkertainen tavalliseen teräkseen verrattuna. Hakkaavassa työstössä terien kestoikä oli molemmilla materiaaleilla sama. Työssä suoritettujen kokeiden ja kustannuslaskelmien perusteella, käyttämällä M-käsiteltyä terästä voidaan pienentää valmistuskustannuksia. Materiaalien välinen ero korostuu, kun hakkaavaa työstöä on vähän, sarjat ovat suuria ja tuotanto on miehittämätöntä.

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Abstract:Trematodes belonging to the family Eucotylidae, including Tanaisia(Paratanaisia)bragaiSantos, 1934are parasites of the kidney and ureter that affect several species of domestic and wild birds. Tanaisia bragaiis considered a low pathogenic parasite, but high worm burdens may determine clinical complications, including signs of apathy, weight loss, diarrhea and death. This paper describes the first report of infection by T. bragai in peacocks (Pavo cristatus), which constitutes a new host record and offers data on the lesions associated to this parasitism, although the degree of pathogenicity and parasite load may be considered mild. These birds did not exhibit clinical signs of parasitism. The macroscopic exam revealed discreet yellow spots on the liver. In the histological sections of the kidney, specimens of T. bragai were found in the collecting ducts, which were markedly dilated, with a thickened wall. Other findings included a mild inflammatory reaction in the wall of the ducts (but sometimes absent), flattening of lining epithelial cells and small, multifocal points of calcification around the collecting ducts. The microscopic examination of the parasites revealed trematodes with an elongated body, well-developed sub terminal oral sucker, pharynx present, short esophagus, cecum somewhat undulating or not, with blind end, testes symmetrical, equatorial, irregular in shape or slightly lobed, vitelline fields extending in both pre-ovarian and post ovarian fields, uterus very long, intercecal or sometimes overlapping the cecum and containing large quantities of eggs. The present findings suggest the need for further diagnostic studies on the prevalence of this trematode in peacocks as well as pathologic studies for the determination of the potential pathogenicity of this parasite in this species of bird. Moreover, infected peacocks could serve as carriers of T. bragai to be transferred to other bird species, thereby contributing to the dispersion of the parasite.

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An axisymmetric supersonic flow of rarefied gas past a finite cylinder was calculated applying the direct simulation Monte Carlo method. The drag force, the coefficients of pressure, of skin friction, and of heat transfer, the fields of density, of temperature, and of velocity were calculated as function of the Reynolds number for a fixed Mach number. The variation of the Reynolds number is related to the variation of the Knudsen number, which characterizes the gas rarefaction. The present results show that all quantities in the transition regime (Knudsen number is about the unity) are significantly different from those in the hydrodynamic regime, when the Knudsen number is small.

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This thesis describes work related to the in-depth characterization of the phenolic compounds of silver birch (Betula pendula) inner bark. Phenolic compounds are the most ubiquitous class of plant secondary compounds. The unifying feature of this structurally diverse group is an aromatic ring containing at least one hydroxyl group. Due to the structural diversity, phenolics have various roles in the plant defense against biotic and abiotic stresses. In addition, they can confer several health-promoting properties to humans. Furthermore, the structural diversity of this class of compounds causes challenges for their analysis. The study species in the present work, silver birch, is economically the most important hard wood species in northern Europe. Its inner bark contains a high level of phenolic compounds and it has shown one of the strongest antioxidant activities among 92 Finnish plant materials. The literature review surveys the diversity and organ specific distribution of phenolic compounds in silver birch as well as the proposed ecological functions of phenolic compounds in nature. In addition, the basis for the characterization of phenolics by mass spectrometry (MS), nuclear magnetic resonance spectroscopy (NMR), and circular dichroism spectroscopy (CD) are reviewed. The objective of the experimental work was to extract, purify, characterize, and quantify the inner bark phenolic compounds. Overall 36 compounds were characterized by MS and ultraviolet spectroscopy (UV). 24 compounds were isolated and their structures confirmed by NMR and CD spectroscopy. Five novel natural compounds were identified. Special emphasis was placed on the establishment of a method for the characterization of proanthocyanidins (PAs). Hydrophilic interaction liquid chromatography (HILIC) was utilized because of its high resolution power and predictable elution order of oligomeric and polymeric PAs according to an increasing degree of polymerization. The combination of HILIC and high-resolution MS detection allowed the identification of procyanidin (PC) polymers up to the degree of polymerization of 22. In addition, a series of oligomeric and polymeric PC monoxylosides were observed for the first time in nature. Season and genotype influenced the quantities of the main inner bark phenolics, yet qualitative differences were not observed. However, manual wounding of the inner bark induced the production of ellagitannins (ETs) in the wounded tissues, i.e. callus. Since ETs were not detected in the intact inner bark, this finding may reflect the capacity of silver birch to exploit ellagitannins in its defense.

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Male germ cell differentiation, spermatogenesis is an exceptional developmental process that produces a massive amount of genetically unique spermatozoa. The complexity of this process along with the technical limitations in the germline research has left many aspects of spermatogenesis poorly understood. Post-meiotic haploid round spermatids possess the most complex transcriptomes of the whole body. Correspondingly, efficient and accurate control mechanisms are necessary to deal with the huge diversity of transcribed RNAs in these cells. The high transcriptional activity in round spermatids is accompanied by the presence of an uncommonly large cytoplasmic ribonucleoprotein granule, called the chromatoid body (CB) that is conjectured to participate in the RNA post-transcriptional regulation. However, very little is known about the possible mechanisms of the CB function. The development of a procedure to isolate CBs from mouse testes was this study’s objective. Anti-MVH immunoprecipitation of cross-linked CBs from a fractionated testicular cell lysate was optimized to yield considerable quantities of pure and intact CBs from mice testes. This protocol produced reliable and reproducible data from the subsequent analysis of CB’s protein and RNA components. We found that the majority of the CB’s proteome consists of RNA-binding proteins that associate functionally with different pathways. We also demonstrated notable localization patterns of one of the CB transient components, SAM68 and showed that its ablation does not change the general composition or structure of the CB. CB-associated RNA analysis revealed a strong accumulation of PIWI-interacting RNAs (piRNAs), mRNAs and long non-coding RNAs (lncRNAs) in the CB. When the CB transcriptome and proteome analysis results were combined, the most pronounced molecular functions in the CB were related to piRNA pathway, RNA post-transcriptional processing and CB structural scaffolding. In addition, we demonstrated that the CB is a target for the main RNA flux from the nucleus throughout all steps of round spermatid development. Moreover, we provided preliminary evidence that those isolated CBs slice target RNAs in vitro in an ATPdependent manner. Altogether, these results make a strong suggestion that the CB functions involve RNA-related and RNA-mediated mechanisms. All the existing data supports the hypothesis that the CB coordinates the highly complex haploid transcriptome during the preparation of the male gametes for fertilization. Thereby, this study provides a fundamental basis for the future functional analyses of ribonucleoprotein granules and offers also important insights into the mechanisms governing male fertility.

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The main aim of this thesis is to study the effect of mineral fillers on the properties of extruded wood-polypropylene composites (WPC). The studied minerals are Talc, Calcite (CaCO3), two quantities of Wollastonite and Soapstone, and the level of mineral addition is 20 w-%. The study shows that mineral fillers can be used to modify and improve the properties of woodplastic composites. Especially the moisture-related properties of WPCs were found to be improved significantly by mineral addition. As the WPCs of the studied type are commonly used in outdoor applications, this is of importance in terms of usability. In machining, the addition of two minerals retained the surface roughness at same level throughout the test, indicating a favorable effect on machinability. The use of hard minerals shortened the tool life in machining. In general, a modest increase in density was observed. In many of the studied properties, no apparent influence of mineral addition was found, indicating that the properties were not weakened. An overall result was that talc showed the best overall performance, indicating that it can be used as an active filler improving most of the studied properties, especially moisture resistance. Calcite was found to have nearly similar performance. According to the findings, mineral addition to wood-plastic composites appears to be beneficial; especially moisture resistance can be enhanced without diminishing the other properties or usability in general.

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Tässä työssä tarkoituksena on tutkia mahdollisuuksia sellutehtaan eri jätevesien puhdistukseen uudelleenkäyttöä varten. Yleensä tutkimuksen kohteena ovat yleensä valkaisun alkalisen suodokset, koska niiden suodattaminen on ollut helppoa membraanitekniikalla. Tässä tutkimuksessa kuitenkin kiinnostuksen kohteena ovat valkaisun happamat suodokset ja kuorimon jätevedet. Tutkimuksessa käytettiin viittä membraania, joista kolme on ultrasuodatusmembraaneja ja kaksi nanosuodatusmembraaneja. Näiden katkaisukoot ovat väillä 30 000 -200 Da. Konsentraatiosuodatukset suoritettiin CR 250 -suodattimella. Syötöstä, konsentraatista ja permeaatista otettujen näytteiden analyysien pohjalta laskettujen retentioiden perusteella nanosuodatusmembraani NF270 antoi parhaan tuloksen. Tällä membraanilla kuorimon jätevesien suodatuksessa retentioksi saatiin kaikilla osa-alueilla vähintään 80 %, mutta valkaisun happamien suodosten tulokset olivat alhaisempia. Suodatusten perusteella voitiin laskea tarvittava kapasiteetti ja suodatuspinta-ala suodatus yksiköille. Kummassakin tapauksessa suodatuksen syöttömäärät määräytyivät erään suomalaisen sellutehtaan valkaisussa ja kuorimolla syntyvien jätevesimäärien mukaan. Suodatusyksiköiden kooksi saatiin valkaisun happamien suodosten suodattamiseen 54 CR 1010 -suodatinta ja kuorimon jätevesien suodattamiseen 4 CR 1010-suodatinta.