ANGIOTENSINERGIC AND CHOLINERGIC RECEPTORS OF THE SUBFORNICAL ORGAN MEDIATE SODIUM INTAKE INDUCED BY GABAergic ACTIVATION OF THE LATERAL PARABRACHIAL NUCLEUS

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Differential modulation of sympathetic and respiratory activities by cholinergic mechanisms in the nucleus of the solitary tract in rats

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Involvement of the median preoptic nucleus in blood pressure control

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

LESION OF THE COMMISSURAL NUCLEUS OF THE SOLITARY TRACT/A2 NORADRENERGIC NEURONS FACILITATES THE ACTIVATION OF ANGIOTENSINERGIC MECHANISMS IN RESPONSE TO HEMORRHAGE

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Participation of the dorsal periaqueductal grey matter in the hypoxic ventilatory response in unanaesthetized rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Synaptic plasticity and sensory-motor improvennent following fibrin sealant dorsal root reimplantation and mononuclear cell therapy

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Comunicação do status social pela exibição da nadadeira dorsal

No presente estudo, avaliamos se a exibição da nadadeira dorsal é usada na comunicação do status social na tilápia do Nilo. Medimos o grau de expansão da nadadeira dorsal de peixes durante confrontos que levassem ao estabelecimento de hierarquia de dominância (em isolamento, antes e após estabelecimento hierárquico). Foram observados dez pares de peixes, dos quais 7 claramente estabeleceram a hierarquia de dominância. Antes do pareamento, o grau de expansão da nadadeira dorsal (GEN) não diferiu entre os animais. Com o pareamento, mas antes da definição hierárquica, o GEN aumentou de forma similar para ambos os animais dos pares e os indivíduos de cada par emitiram taxas de confrontos equivalentes. Porém, após a definição hierárquica, tanto o GEN quanto as taxas de confrontos se mantiveram nos dominantes, reduzindo drasticamente nos submissos. Esses dados mostram que o GEN é um sinal indicativo da posição hierárquica dos peixes, podendo transmitir informação de dominância (elevação do GEN) ou submissão (redução do GEN)

Median preoptic nucleus mediates the cardiovascular recovery induced by hypertonic saline in hemorrhagic shock

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Gabaergic and opioid receptors mediate the facilitation of NaCl intake induced by α₂-adrenergic activation in the lateral parabrachial nucleus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Moxonidine into the lateral parabrachial nucleus modifies postingestive signals involved in sodium intake control

The activation of a2-adrenoceptors with bilateral injections of moxonidine (a2-adrenoceptor and imidazoline receptor agonist) into the lateral parabrachial nucleus (LPBN) increases 1.8% NaCl intake induced by treatment with furosemide (FURO) + captopril (CAP) subcutaneously. In the present study, we analyzed licking microstructure during water and 1.8% NaCl intake to investigate the changes in orosensory and postingestive signals produced by moxonidine injected into the LPBN. Male Sprague–Dawley rats were treated with FURO + CAP combined with bilateral injections of vehicle or moxonidine (0.5 nmol/0.2 ll) into the LPBN. Bilateral injections of moxonidine into the LPBN increased FURO + CAP-induced 1.8% NaCl intake, without changing water intake. Microstructural analysis of licking behavior found that this increase in NaCl intake was a function of increased number of licking bursts from 15 to 75 min of the test (maximum of 49 ± 9 bursts/bin, vs. vehicle: 2 ± 2 bursts/bin). Analysis of the first 15 min of the test, when most of the licking behavior occurred, found no effect of moxonidine on the number of licks/burst for sodium intake (24 ± 5 licks/burst, vs. vehicle: 27 ± 8 licks/burst). This finding suggests that activation of a2-adrenoceptors in the LPBN affects postingestive signals that are important to inhibit and limit sodium intake by FURO + CAP-treated rats.

Sodium intake combining cholinergic activation and noradrenaline into the lateral parabrachial nucleus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)