916 resultados para Contacts Sharing, CRM, Cloud Google, API, SugarCRM, Web Service, App Engine


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Los trastornos del comportamiento alimentario (TCA) son las patologías psicológicas que más se han incrementado en los últimos años. Uno de los factores que determina la elevada prevalencia de TCA en nuestra sociedad es el gran desconocimiento sobre alimentación. Este desconocimiento puede deberse a la consulta de recursos online sin validez científica. El objetivo de este trabajo ha sido analizar la calidad científica y el posicionamiento de los sitios web en español con información sobre nutrición, TCA y obesidad. Material y métodos: Se realizó una búsqueda de páginas web en el navegador Google Chrome con las palabras clave: dieta, anorexia, bulimia, nutrición y obesidad, seleccionándose los 20 primeros resultados de cada búsqueda según los índices de posicionamiento ofrecidos por SEOquake (Page Rank, Alexa Rank y SEMrush Rank). Las variables de análisis fueron: información relacionada con dietas y hábitos alimentarios, información sobre alimentación saludable, información sobre TCA y sus criterios diagnósticos e información de carácter formativo acerca de temas profesionales de salud general. Sólo el 50% de las web encontradas cumplían los criterios de inclusión en el estudio. La mayoría no seguían las pautas establecidas por e-Europa sobre calidad. La mediana de Page Rank fue de 2, excepto en aquellas asociadas a instituciones sanitarias de prestigio. Dada la escasez de webs sanitarias con rigor científico, es imprescindible la revisión de las existentes y la creación de nuevos espacios on-line cuya supervisión sea realizada por profesionales especialistas en salud y nutrición.

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En el presente trabajo se realiza una investigación acerca de la tecnología de liofilización, que comprende un análisis cuantitativo y cualitativo. Esto con la finalidad de conocer la posibilidad de exportar frutas liofilizadas a países pertenecientes de la Unión Europea y la EFTA. La investigación inicia con la recolección de información como la historia de la tecnología de liofilización, su proceso, ventajas y desventajas de aplicación, equipos y funciones necesarias para su realización y se ejemplifican dos empresas colombianas que en la actualidad utilizan esta tecnología. Adicionalmente, se evidencia la diferencia que existe entre este proceso y la deshidratación con calor. Posteriormente, se realiza una matriz de selección de países en la que se tienen en cuenta variables políticas, económicas, culturales y legales de los 32 países pertenecientes a la Unión Europea y la EFTA. Con base en esto se eligieron los dos países cuyo resultado presentaba mayor favorabilidad para la actividad a realizar, estos fueron Suiza y Suecia, para los cuales se hizo un estudio de mercado, teniendo en cuenta seis etapas: contactos, potencial de ventas del mercado, análisis competitivo, condiciones de entrada al país, condiciones financieras y de entrada al mercado y selección del país objetivo. Finalmente se presentan las conclusiones y recomendaciones que la información recolectada permitió obtener.

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In the last few years, mobile wireless technology has gone through a revolutionary change. Web-enabled devices have evolved into essential tools for communication, information, and entertainment. The fifth generation (5G) of mobile communication networks is envisioned to be a key enabler of the next upcoming wireless revolution. Millimeter wave (mmWave) spectrum and the evolution of Cloud Radio Access Networks (C-RANs) are two of the main technological innovations of 5G wireless systems and beyond. Because of the current spectrum-shortage condition, mmWaves have been proposed for the next generation systems, providing larger bandwidths and higher data rates. Consequently, new radio channel models are being developed. Recently, deterministic ray-based models such as Ray-Tracing (RT) are getting more attractive thanks to their frequency-agility and reliable predictions. A modern RT software has been calibrated and used to analyze the mmWave channel. Knowledge of the electromagnetic properties of materials is therefore essential. Hence, an item-level electromagnetic characterization of common construction materials has been successfully achieved to obtain information about their complex relative permittivity. A complete tuning of the RT tool has been performed against indoor and outdoor measurement campaigns at 27 and 38 GHz, setting the basis for the future development of advanced beamforming techniques which rely on deterministic propagation models (as RT). C-RAN is a novel mobile network architecture which can address a number of challenges that network operators are facing in order to meet the continuous customers’ demands. C-RANs have already been adopted in advanced 4G deployments; however, there are still some issues to deal with, especially considering the bandwidth requirements set by the forthcoming 5G systems. Open RAN specifications have been proposed to overcome the new 5G challenges set on C-RAN architectures, including synchronization aspects. In this work it is described an FPGA implementation of the Synchronization Plane for an O-RAN-compliant radio system.

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Quello che intendo studiare sono i più importanti interventi antimonopolio negli ultimi 20 anni, per quanto riguarda le grandi potenze del web ossia Amazon, Apple, Google, Microsoft e Facebook. In particolare approfondirò tutti gli interventi applicati negli Stati Uniti d’America e in Europa nelle varie fasi temporali, ovvero dalla nascita dei colossi della rete, fino ad arrivare al periodo prepandemia, considerando che quest’ultima ha rappresentato un evento durante il quale si sono verificati dei cambiamenti fondamentali che hanno richiesto da parte delle autorità, ulteriori e successivi interventi e controlli per evitare abusi di potere. Ai fini della ricerca sarà importante studiare le origini della regolamentazione antitrust, sia in USA che in Europa da un punto di vista storico. Di conseguenza questi giganti del web hanno avuto l’opportunità di affermare il proprio potere e a volte di abusarne tanto da intensificare le attenzioni dell’antitrust nei loro confronti. Di conseguenza le vicende saranno seguite quotidianamente per mantenere lo studio aggiornato. Si tratta infatti di un settore in continuo divenire, la cui analisi sarebbe priva di significato senza una costante attenzione verso i cambiamenti.

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I notevoli sviluppi tecnologici che hanno caratterizzato l’ultimo decennio hanno portato con sé alcune minacce alla sicurezza. In questa tesi, completamento di un progetto di tirocinio svolto presso il CINECA, ci si concentra sulla realizzazione di una baseline dinamica in grado di apprendere il comportamento degli utenti. Grazie ad essa e con l’aiuto di uno script Python, è possibile rilevare i comportamenti anomali e segnalarli agli interessati. Il focus principale del progetto riguarda il possibile esaurimento di sessioni in applicazioni web e la conseguente negazione del servizio. La raccolta dei dati dai vari applicativi è stata possibile utilizzando il SIEM QRadar di IBM, le funzionalità in esso presenti e le API che hanno consentito un agevole interfacciamento con gli script esterni.

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Negli ultimi anni, a causa degli enormi progressi dell’informatica e della sempre crescente quantità di dati generati, si è sentito sempre più il bisogno di trovare nuove tecniche, approcci e algoritmi per la ricerca dei dati. Infatti, la quantità di informazioni da memorizzare è diventata tale che ormai si sente sempre più spesso parlare di "Big Data". Questo nuovo scenario ha reso sempre più inefficaci gli approcci tradizionali alla ricerca di dati. Recentemente sono state quindi proposte nuove tecniche di ricerca, come ad esempio le ricerche Nearest Neighbor. In questo elaborato sono analizzate le prestazioni della ricerca di vicini in uno spazio vettoriale utilizzando come sistema di data storage Elasticsearch su un’infrastruttura cloud. In particolare, sono stati analizzati e messi a confronto i tempi di ricerca delle ricerche Nearest Neighbor esatte e approssimate, valutando anche la perdita di precisione nel caso di ricerche approssimate, utilizzando due diverse metriche di distanza: la similarità coseno e il prodotto scalare.

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In epoca contemporanea, la tecnologia ha subito una diffusione massiva e ha pervaso ogni ambito della vita dell’uomo, che sia esso scolastico, lavorativo, o ludico, cambiandone così radicalmente lo stile di vita sotto tutti i punti di vista. Sono infatti numerosissimi gli strumenti informatici che ad oggi supportano l'esercizio della maggior parte delle professioni, e che risultano peraltro ogni giorno più accurati e potenti: questo è il caso di Nutribook, un software gestionale in-cloud pensato per assistere i professionisti del mondo della nutrizione (Biologi Nutrizionisti, Dietologi, Dietisti) nelle attività quotidiane di visita dei pazienti e nell’organizzazione della propria agenda. Nell'ottica di poter offrire agli utenti un servizio sempre più esteso, il presente elaborato riporta il progetto di tesi svolto presso Deasoft s.r.l., azienda proprietaria di Nutribook, volto ad integrare tale software con un modulo dedicato all’attività di elaborazione di diete e piani alimentari. L'obiettivo principale del progetto presentato nell’elaborato risiede non solo nell'aspetto realizzativo del prodotto, ma anche nel tentativo di renderne la fruizione da parte dell'utente target il più possibile semplice, intuitiva e soddisfacente, mediante tecniche di potenziamento della User Experience. Il tirocinio per la redazione della presente tesi, nato a partire dall’esperienza di tirocinio curricolare, ha previsto come attività principali la conduzione di studi approfonditi in materia di User Experience, la partecipazione alla fase di analisi del dominio e dei requisiti e, infine, la collaborazione al design delle interfacce da realizzare mediante prototipi.

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High-throughput screening of physical, genetic and chemical-genetic interactions brings important perspectives in the Systems Biology field, as the analysis of these interactions provides new insights into protein/gene function, cellular metabolic variations and the validation of therapeutic targets and drug design. However, such analysis depends on a pipeline connecting different tools that can automatically integrate data from diverse sources and result in a more comprehensive dataset that can be properly interpreted. We describe here the Integrated Interactome System (IIS), an integrative platform with a web-based interface for the annotation, analysis and visualization of the interaction profiles of proteins/genes, metabolites and drugs of interest. IIS works in four connected modules: (i) Submission module, which receives raw data derived from Sanger sequencing (e.g. two-hybrid system); (ii) Search module, which enables the user to search for the processed reads to be assembled into contigs/singlets, or for lists of proteins/genes, metabolites and drugs of interest, and add them to the project; (iii) Annotation module, which assigns annotations from several databases for the contigs/singlets or lists of proteins/genes, generating tables with automatic annotation that can be manually curated; and (iv) Interactome module, which maps the contigs/singlets or the uploaded lists to entries in our integrated database, building networks that gather novel identified interactions, protein and metabolite expression/concentration levels, subcellular localization and computed topological metrics, GO biological processes and KEGG pathways enrichment. This module generates a XGMML file that can be imported into Cytoscape or be visualized directly on the web. We have developed IIS by the integration of diverse databases following the need of appropriate tools for a systematic analysis of physical, genetic and chemical-genetic interactions. IIS was validated with yeast two-hybrid, proteomics and metabolomics datasets, but it is also extendable to other datasets. IIS is freely available online at: http://www.lge.ibi.unicamp.br/lnbio/IIS/.

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Trees from tropical montane cloud forest (TMCF) display very dynamic patterns of water use. They are capable of downwards water transport towards the soil during leaf-wetting events, likely a consequence of foliar water uptake (FWU), as well as high rates of night-time transpiration (Enight) during drier nights. These two processes might represent important sources of water losses and gains to the plant, but little is known about the environmental factors controlling these water fluxes. We evaluated how contrasting atmospheric and soil water conditions control diurnal, nocturnal and seasonal dynamics of sap flow in Drimys brasiliensis (Miers), a common Neotropical cloud forest species. We monitored the seasonal variation of soil water content, micrometeorological conditions and sap flow of D. brasiliensis trees in the field during wet and dry seasons. We also conducted a greenhouse experiment exposing D. brasiliensis saplings under contrasting soil water conditions to deuterium-labelled fog water. We found that during the night D. brasiliensis possesses heightened stomatal sensitivity to soil drought and vapour pressure deficit, which reduces night-time water loss. Leaf-wetting events had a strong suppressive effect on tree transpiration (E). Foliar water uptake increased in magnitude with drier soil and during longer leaf-wetting events. The difference between diurnal and nocturnal stomatal behaviour in D. brasiliensis could be attributed to an optimization of carbon gain when leaves are dry, as well as minimization of nocturnal water loss. The leaf-wetting events on the other hand seem important to D. brasiliensis water balance, especially during soil droughts, both by suppressing tree transpiration (E) and as a small additional water supply through FWU. Our results suggest that decreases in leaf-wetting events in TMCF might increase D. brasiliensis water loss and decrease its water gains, which could compromise its ecophysiological performance and survival during dry periods.

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A utilização da web para a disponibilização de informações e serviços de órgãos governamentais para os cidadãos tem se tornado cada vez mais expressiva. Assim, a garantia de que esses conteúdos e serviços possam ser acessíveis a qualquer cidadão é imprescindível, independentemente de necessidades especiais ou de quaisquer outras barreiras. No Brasil, o Decreto-Lei nº5.296/2004 determinou que todos os órgãos governamentais deveriam adaptar seus sítios na web de acordo com critérios de acessibilidade até dezembro de 2005. Com o objetivo de verificar a evolução da acessibilidade ao longo dos anos e como foi o impacto dessa legislação, este artigo analisa a acessibilidade dos sítios dos governos estaduais brasileiros por meio de amostras coletadas entre 1996 e 2007. Foram efetuadas análises por meio de métricas, obtidas por avaliações com ferramentas automáticas. Os resultados indicam que a legislação teve pouco impacto para a melhoria real da acessibilidade dos sítios no período indicado, com uma melhora somente em 2007. Verifica-se que se faz necessário adotar políticas públicas mais efetivas para que as pessoas com necessidades especiais tenham os seus direitos para acesso a informações e aos serviços públicos na web assegurados mais amplamente.

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OBJECTIVE: To assess the perspectives of couples who requested vasectomy in a public health service on the use of male participation contraceptive methods available in Brazil: male condoms, natural family planning/calendar, coitus interruptus and vasectomy. METHODS: A qualitative study with semi-structured interviews was held with 20 couples who had requested vasectomy at the Human Reproduction Unit of the Universidade Estadual de Campinas, Brazil. Data analysis was carried out through thematic content analysis. FINDINGS: The couples did not, in general, know any effective contraceptive options for use by men and/or participating in their use, except for vasectomy. The few methods with male participation that they knew of were perceived to interfere in spontaneity and in pleasure of intercourse. Men accepted that condom use in extra-conjugal relations offered them protection from sexually transmitted diseases; that their wives might also participate in extra-marital relationships was not considered. DISCUSSION: The few contraceptive options with male participation lead to difficulty in sharing responsibilities between men and women. On the basis of perceived gender roles, women took the responsibility for contraception until the moment when the situation became untenable, and they faced the unavoidable necessity of sterilization. CONCLUSIONS: Specific actions are necessary for men to achieve integral participation in relation to reproductive sexual health. These include education and discussions on gender roles, leading to greater awareness in men of the realities of sexual and reproductive health

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A compact frequency standard based on an expanding cold (133)CS cloud is under development in our laboratory. In a first experiment, Cs cold atoms were prepared by a magneto-optical trap in a vapor cell, and a microwave antenna was used to transmit the radiation for the clock transition. The signal obtained from fluorescence of the expanding cold atoms cloud is used to lock a microwave chain. In this way the overall system stability is evaluated. A theoretical model based on a two-level system interacting with the two microwave pulses enables interpretation for the observed features, especially the poor Ramsey fringes contrast. (C) 2008 Optical Society of America.

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Background: Protein-protein interactions (PPIs) constitute one of the most crucial conditions to sustain life in living organisms. To study PPI in Arabidopsis thaliana we have developed AtPIN, a database and web interface for searching and building interaction networks based on publicly available protein-protein interaction datasets. Description: All interactions were divided into experimentally demonstrated or predicted. The PPIs in the AtPIN database present a cellular compartment classification (C(3)) which divides the PPI into 4 classes according to its interaction evidence and subcellular localization. It has been shown in the literature that a pair of genuine interacting proteins are generally expected to have a common cellular role and proteins that have common interaction partners have a high chance of sharing a common function. In AtPIN, due to its integrative profile, the reliability index for a reported PPI can be postulated in terms of the proportion of interaction partners that two proteins have in common. For this, we implement the Functional Similarity Weight (FSW) calculation for all first level interactions present in AtPIN database. In order to identify target proteins of cytosolic glutamyl-tRNA synthetase (Cyt-gluRS) (AT5G26710) we combined two approaches, AtPIN search and yeast two-hybrid screening. Interestingly, the proteins glutamine synthetase (AT5G35630), a disease resistance protein (AT3G50950) and a zinc finger protein (AT5G24930), which has been predicted as target proteins for Cyt-gluRS by AtPIN, were also detected in the experimental screening. Conclusions: AtPIN is a friendly and easy-to-use tool that aggregates information on Arabidopsis thaliana PPIs, ontology, and sub-cellular localization, and might be a useful and reliable strategy to map protein-protein interactions in Arabidopsis. AtPIN can be accessed at http://bioinfo.esalq.usp.br/atpin.

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With the advent and development of technology, mainly in the Internet, more and more electronic services are being offered to customers in all areas of business, especially in the offering of information services, as in virtual libraries. This article proposes a new opportunity to provide services to virtual libraries customers, presenting a methodology for the implementation of electronic services oriented by these customers' life situations. Through analytical observations of some national virtual libraries sites, it could be identified that the offer of services considering life situations and relationship interest situations can promote the service to their customers, providing greater satisfaction and, consequently, improving quality in the offer of information services. The visits to those sites and the critical analysis of the data collected during these visits, supported by bibliographic researches results, have enabled the description of this methodology, concluding that the provision of services on an isolated way or in accordance with the user's profile on sites of virtual libraries is not always enough to ensure the attendance to the needs and expectations of its customers, which suggests the offering of these services considering life situations and relationship interest situations as a complement that adds value to the business of virtual library. This becomes relevant when indicates new opportunities to provide virtual libraries services with quality, serving as a guide to the information providers managers, enabling the offering of new means to access information services by such customers, looking for pro - activity and services integration, in order to solve definitely real problems.

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Background: A relative friability to capture a sufficiently large patient population in any one geographic location has traditionally limited research into rare diseases. Methods and Results: Clinicians interested in the rare disease lymphangioleiomyomatosis (LAM) have worked with the LAM Treatment Alliance, the MIT Media Lab, and Clozure Associates to cooperate in the design of a state-of-the-art data coordination platform that can be used for clinical trials and other research focused on the global LAM patient population. This platform is a component of a set of web-based resources, including a patient self-report data portal, aimed at accelerating research in rare diseases in a rigorous fashion. Conclusions: Collaboration between clinicians, researchers, advocacy groups, and patients can create essential community resource infrastructure to accelerate rare disease research. The International LAM Registry is an example of such an effort.