La rehabilitación y el uso del patrimonio histórico industrial

La reutilización de edificios industriales es un aspecto del proceso de reconversión de suelo industrial en otros usos, el cual se ha acentuado con la reestructuración industrial ligada a la aparición de lo que se denomina ciudad postindustrial. Dicho proceso ha llevado con frecuencia al abandono y a la degradación de los viejos edificios industriales, que muchas veces son derribados y sustituidos por otros nuevos dedicados a viviendas o a usos terciarios. En los dos últimos decenios, sin embargo, la conservación y la reutilización del patrimonio histórico industrial ha adquirido una gran importancia. Los viejos edificios industriales funcionalmente obsoletos poseen, en efecto, valores arquitectónicos y técnicos que hacen a veces necesaria y posible su conservación y reutilización adaptativa. Pero eso exige definir claramente criterios de selección, tras un proceso de inventario y catalogación, en el que deben tenerse en cuenta los criterios generales de catalogación del patrimonio histórico monumental. El artículo discute la conveniencia de conservar edificios funcionalmente obsoletos y aborda la cuestión de las estrategias de defensa, haciendo alusión al papel de los técnicos y a la necesidad del compromiso local.

Les médiations de l'immédiateté : l'individualisme communautaire des assemblées pentecôtistes

Lorsqu'il est amené à témoigner de sa conversion, le membre d'une assemblée pentecôtiste insiste avant tout sur la dimension personnelle de son choix de vie et sur les manifestations divines qui l'ont encouragées et qui l'encouragent encore chaque jour dans cette voie. Avoir fait l'expérience personnelle de l'agir divin est un élément constitutif de tout récit de conversion. Cet article, basée sur des recherches doctorales menées auprès de deux assemblées pentecôtistes de l'Est de la France, cherche à mettre en évidence que cette relation personnelle et intime entre le fidèle et son créateur se construit dans le cadre communautaire : à travers l'harmonisation des récits de conversion et la structuration des réunions de prières assurant par les manifestations charismatiques la mise en présence de l'Esprit Saint au sein de la communauté des fidèles. C'est en effet sur une validation communautaire que reposent en partie les convictions individuelles. When he has to testify of his conversion, the member of a Pentecostal assembly insists above all on the personal dimension of his choice of life and on the divine intervention which has encouraged him and which will encourage him in his everyday life in this way. The personal experience of God's action is a constituent element of any narrative of conversion. This article, based on my PhD researches carried on with two Pentecostal assemblies located in the east of France, tries to highlight that this personal and intimate relation between the believer and his creator is built in the community framework : harmonization of the narratives of conversion, structuralization of the meetings of prayers and charismatic interventions of the Holy Spirit within the community of the believers. Individual convictions are partly based and validated by the community.

Proyecto de plaza para el barrio de La Mina. Proceso de participación ciudadana

Pre-projecte de disseny urbà d'una de les places de La Mina contemplades en el PERI d'aquesta zona

Tallers d'Espai Públic. Carril bici al barri de La Mina

Report of one of the workshops developed in 2005 under the process of public participation: Mapping La Mina (2002-2006). http://www.ub.edu/escult/mina/cartografies/html/9_fase2.html

Cartografies de La Mina. Compilació dels resultats dels tallers de participació ciutadana sobre espai públic 2002-2006

Plataforma d'entitats i veïns/es del barri de La Mina

Projecte Rambla de la Mina. Colors per trepitjar

Aquest projecte deriva d'alguns dels resultats del conjunt de tallers de participació que, amb el nom de Cartografies de La Mina vàrem desenvolupar entre el 2002 i el 2005 amb diversos grups de veïns i veïnes del barri i que queden sintetitzats en el Pla d¿accions de barri en Espai Públic, que vàrem lliurar al Consorci del Barri de La Mina l'abril del 2006.

Projecte d'idees per a la urbanització de la Rambla de la ciutat d'Asunció. Sant Andreu (Barcelona) 2010

El projecte de realitzar una rambla al barri de Baró de Viver en un tram del Carrer Ciutat d'Asunció sorgeix d'un taller de participació ciutadana que es du a terme l'any 2007 amb joves del barri vinculats al servei de dinamització de joves a l'Escola de l'Esperança, organitzat pel Centre de Recerca Polis (UB). La tipologia de rambla es decideix a partir d'un diagnòstic de l'espai públic del barri, on s'identifiquen aquells espais que són susceptibles d'algun tipus d'intervenció que millori la imatge de Baró de Viver.

Tallers d'espai públic. Brutícia al carrer

Report of the workshop developed in 2005 under the process of public participation: Mapping La Mina (http://www.ub.edu/escult/mina)

Tallers d'espai públic. Sant Ramon de Penyafort

Report of one of the workshops developed in 2005 under the process of public participation: Mapping La Mina (2002-2006). http://www.ub.edu/escult/mina

Tallers d'espai públic. Seguretat i Urbanisme

Report of one of the workshops developed in 2005 under the process of public participation: Mapping La Mina (2002-2006). http://www.ub.edu/escult/mina

Barcelona: un modelo de Arte Público y Diseño Urbano

This work is divided into two distinct sections which largely reflected my contributions to the First International Seminar Lima developed at the Pontifical Catholic University of Lima in August 2010.The first section summarizes the process of making the city that are the essence of so-called Barcelona model and have achieved, in terms of strategic planning, Barcelona to be ¿on the map¿ of international best practice in urban design and public art The second section develops the issue of citizen participation in the process of making the city, from the experiences that our research center has launched in the neighborhoods of La Mina and Baró de Viver.

Leaching of nitrogen, potassium, calcium and magnesium in a sandy soil cultivated with sugarcane

A lysimeter experiment was carried out with sugarcane aiming to evaluate the leaching of nitrogen derived from either urea (15N) or the soil/sugarcane crop residues. The leaching of K+, Ca2+, and Mg2+ was also evaluated. The experiment was a factorial 2x4. The influencing factors were: firstly, the differential addition of two kinds of sugarcane remains to the soil, simulating conditions of cane- plantation renewal after the cane crop harvest, with and without previous straw removal by burning; secondly, four doses of N: 0, 30, 60, and 90 kg ha-1. During the experimental period the total volume of water received by the sugarcane-soil system was 2,015 mm, with 1,255 mm as precipitation and 760 mm as irrigation. The loss of N by leaching from the fertilizer (15N) was not detected. In the first three weeks the largest losses of N by leaching occurred, originating from the soil/sugarcane remains-N. The mean of leached N during the experimental period of 11 months was of 4.5 kg ha-1. The mean losses of K+, Ca2+, and Mg2+ were of 13, 320 and 80 kg ha-1, respectively.

Croire ensemble. Analyse institutionnelle du paysage religieux en Suisse

L'étude présentée dans cet ouvrage offre pour la première fois en Suisse une perspective sociologique empirique et générale sur les organisations religieuses locales. Vu sous cet angle, le fait religieux se manifeste d'abord, comme le précisaient déjà Weber ou Durkheim, par l'existence de communautés de tailles et de profils divers, tant dans l'espace rural qu'urbain. En Suisse, 5'734 paroisses et groupes religieux ont pu être dénombrés en 2008. Ce recensement permet de souligner la prégnance institutionnelle des Eglises historiques, mais également l'émergence d'une plus forte pluralité religieuse, particulièrement en milieu urbain. La sociologie des organisations que propose cette étude permet de jeter un éclairage nouveau sur les effets de la sécularisation (baisse des membres et de la pratique) et de la pluralisation (diversification des confessions et traditions religieuses). L'analyse des différences et des similitudes organisationnelles selon les traditions religieuses fait apparaître un positionnement social des groupes en fonction de statuts acquis au cours de l'histoire. Les théories classiques - par exemple à pro- pos des relations entre statuts sociaux des membres et groupes d'appartenance, des types d'autorités religieuses ou encore des différences entre Eglise et Secte - sont revisitées, précisées ou reformulées grâce à des données quantitatives originales et représentatives du champ religieux suisse. -- The study presented in this book for the first time in Switzerland offers a broad empirical and sociological perspective on local religious organizations. From this perspective, religion appears first, as already observed by Weber and Durkheim, through communities regardless of their various profiles. In Switzerland, 5,734 parishes and religious groups have been identified by a national census in 2008. The book underlines the institutional salience of historical churches (Reformed and Roman Catholic) but also the emerging religious plurality, particularly in urban areas. This study sheds a new light upon the effects of secularization (lower limbs and practice) and pluralisation (diversification of religious denominations and traditions) in the organizational field. The analysis of differences and similarities between religious traditions shows a social positioning of the local groups according to the statutes acquired in history. The classical theories − e.g. about the relationship between social status of members and membership groups, types of religious authorities or differences between Church and Sect − are revisited, clarified or reformulated based on an original and representative quantitative data of the Swiss religious field.

EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells

Introduction: Cancer stem cells (CSC) display plasticity and self renewal properties reminiscent of normal tissue stem cells but the events responsible for their emergence remain obscure. We have recently identified CSC in Ewing sarcoma family tumors (ESFT) and shown that they arise from mesenchymal stem cells from the bone marrow. Objective of the study: To analyze the mechanisms underlying cancer stem cell development in ESFT. Methods: Primary human mesenchymal stem cells (MSC) isolation from adult and pediatric bone marrow. Retroviral delivery of fusion protein (EWS-FLI1) to primary MSC, and transcriptional and phenotypical analysis. Results: We show that the EWS-FLI-1 fusion gene, associated wit 85-90% of ESFT and believed to initiate their pathogenesis, induces expression of the embryonic stem cell (ESC) genes OCT4, SOX2 and NANOG in human pediatric MSC (hpMSC) but not in their adult counterparts. Moreover, under appropriate culture conditions, hpMSC expressing EWS-FLI-1 generate a cell subpopulation displaying ESFT CSC features in vitro. We further demonstrate that induction of the ESFT CSC phenotype is the result of the combined effect of EWSFLI- 1 on its target gene expression and repression of microRNA-145 (miRNA145) promoter activity. Finally, we provide evidence that EWS-FLI-1 and miRNA-145 function in a mutually repressive feedback loop and identify their common target gene SOX2, in addition to miRNA145 itself, as key players in ESFT cell differentiation and tumorigenicity. Conclusion: Our observations provide insight for the first time into the mechanisms whereby a single oncogene can reprogram primary cells to display a cancer stem cell phenotype.

SITC 26th annual meeting - summary.

ABSTRACT: The 26th annual meeting of the Society for Immunotherapy of Cancer took place in Bethesda on November 4 to 6, 2011 and was organized by Charles G. Drake (Johns Hopkins University) Dolores J. Schendel (Helmholtz Zentrum Muenchen - German Research Center for Environmental Health Institute of Molecular Immunology), Jeffrey Schlom (National Cancer Institute, National Institutes of Health), and Jedd D. Wolchok (Memorial Sloan-Kettering Cancer Center). It was an event marked by a number of extraordinary circumstances: it attracted a record attendance of 805 participants from 24 different countries. The gathering came in the wake of great as well as very sad news for the tumor immunology community. Good news included the approval of anti-CTLA-4 as a therapy for metastatic melanoma in April and the announcement in early October of the Nobel Prize in Physiology and Medicine awarded to pioneering studies in the field of immunology. Indeed, one part of the prize went to Dr. Bruce Beutler, Scripps Research Institute, La Jolla, USA and Dr. Jules Hoffman, Institute for Molecular Cell Biology, Strasbourg, France, for their discoveries in innate immunity and the other part to Dr. Ralph Steinman, The Rockfeller University, New York, for his discovery of dendritic cells. Sad news was the losses of two giants in the field. Jürg Tschopp of the University of Lausanne in March and Ralph Steinman, who passed away just three days before his Nobel Prize announcement. The loss of these two charismatic scientific leaders was particularly sad for the Annual Meeting as both J. Tschopp and R. Steinman were confirmed speakers at this meeting: the former to deliver the keynote lecture and the latter as recipient of the Richard V. Smalley prize.