Ecotoxicological Evaluation of Poly(epsilon-Caprolactone) Nanocapsules Containing Triazine Herbicides

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Toxicity assessment of TiO2 nanoparticles in zebrafish embryos under different exposure conditions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A new species of brachycephalus (anura: brachycephalidae) from the highlands of the atlantic forest, southeastern Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Cálculo K: uma abordagem alternativa para a relatividade especial

In this paper we present an alternative approach due to Bondi for the special theory of relativity. During the development, we analyse the Bondi diagrams, visual resources from which we can take some information about the analysed systems, and we discuss the K factor of Bondi's theory, which is in the core of this work. We then discuss some of the main results obtained from Einstein's special theory of relativity such as the time dilation, spatial contraction and simultaneity of spatially separated events, besides the Lorentz transformations. We also show other two important results in physics coming from K calculus: the relativistic linear momentum and the total relativistic energy.

Minimal levels of ultraviolet light enhance the toxicity of TiO2 nanoparticles to two representative organisms of aquatic systems

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The Use of Headspace Solid-Phase Microextraction (HS-SPME) to Assess the Quality and Stability of Fruit Products: An Example Using Red Mombin Pulp (Spondias purpurea L.)

The present study aimed to evaluate the volatiles profile of red mombin (Spondias purpurea) pulp and its powder produced by spray-drying (SD) as an example to show utility of headspace solid-phase microextraction (HS-SPME) in the analysis of parameters such as the quality and stability of fruit products. Volatiles profiles of the pulp were identified by gas chromatography-mass spectrometry (GC-MS), quantified by gas chromatography-flame ionization detector (GC-FID) and compared to the profile of the powder stored at 0, 60 and 120 days in plastic (PP) or laminated packages (LP). The results showed that the technique was able to identify 36 compounds in the red mombin pulp, 17 out of which have been described for the first time in this fruit, showing that red mombin fresh pulp appears to be unique in terms of volatiles composition. However, only 24 compounds were detected in the powder. This decrease is highly correlated (r(2) = 0.99), at least for the majority of compounds, to the degree of volatility of compounds. Furthermore, the powder stored in PP or LP showed no statistical differences in the amounts of its components for a period of 120 days of storage. Finally, this work shows how HS-SPME analysis can be a valuable tool to assess the quality and stability of fruit products.

Poesia visual e poética postal

Ce travail cherche montrer quelques caractéristiques de la Poésie Visuel, expresion artistique qui melange le langage verbal et le langage visuel à tel point qu´on ne peut pas afirmer une classification appuyée sur les genres traditionnels. Aprés une curte presentation des chemins et des points polémiques de cette esthétique, on analyse comme exemple deux compositions sorties de le grand réseau de communication de l´Art Postal qui est né les années soixante et survit aujourd´hui avec intensité. L´Art Postal a une structure fondé sur la simultanéité de l´information que ressamble à la forme de la poésie visuel. Cettes compositions contemporaines sont confrontées à la tradition du poème visuel qui commence peut-être à l´époque des premiers écrits de hiéroglyphe. Elles sont analysées, donc, dans son originalité. A partir des analyses realisées dans le but de révéler les significations, on arrive à la question proposé par Wilcon Joia Pereira : la nécessité de se comprendre d´une façon nouvelle les expériences esthétiques oú les mots deviennent des images

Evolução Nerd: sociedade digital e as mudanças nos paradigmas sociais dos Nerds e Geeks

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Obtention and characterization of collagen and chitosan based cements for bone regerneration. Part 1: extraction and characterization of collagen

Several cements are used as biomaterials. Biopolymers such as chitosan and collagen exhibit excellent biocompatibility and can be used in the remodeling of bone tissue. The cement must have high mechanical strength and compatibility with original tissue. In this context, the objective of this study was to extract, characterize and cross-link collagen from bovine tendon, forlater associate it with chitosan and calcium phosphate to obtain cements for bone regeneration. Glutaraldehyde was used as cross-linker in 0.1, 0.5, 1.0 and 10% concentration. Infrared analysis confirmed the presence of functional groups characteristic of collagen, whereas the capacity of water absorption decreased with the increasing of cross-linking degree. Denaturation temperatures of collagen samples were obtained by Differential Scanning Calorimetry and Scanning Electron Microscopy showed the fiber structure characteristics of collagen, which were more organized for high degree of cross-linking samples.

Human identification by means of conventional and digital Cheiloscopy: a study of the literature

One of the areas of human identification is Cheiloscopy, the name given to the study of the lips, their characteristics (such as thickness, position of the grooves and grooves) and the record of the impressions left by them. There are variations in the layout of the lines and fissures of the lips, which are unique to each individual, permanent and unchanging. The lip print rarely changes, enduring minor traumas such as inflammation or sores. In criminal investigations, lip prints, visible through the presence of lipstick, can be found on glasses, napkins, clothes, cigarettes, indicating a relationship between the subject and the scene of the crime. Latent impressions may be revealed employing specific chemicals such as powder of silver and aluminum nitrate. Although it is not a very common method, Cheiloscopy may become very useful in forensics due to the extensive amount of valuable information that it brings. The objective of this study was to review the literature on the use of Cheiloscopy in human identification, using traditional and digital methods. It was found that the literature is still in need of studies in this area. The advent of new digital technologies can facilitate the implementation of technical expertise, generating speed and objectivity. New research studies are necessary, especially in the development of digital methods. The application of Cheiloscopy can greatlyhelp with Law, in the identification of living suspects and dead individuals. In the end the benefit will fall to society as a whole.

Pesquisas em animais: uma reflexão bioética

Animal models are an important tool in scientific research. It is known that this practice must be based on bioethical principles in order to impose limits about pain and suffering, or for inspecting proceedings and research site. This study has as aim to evaluate and present current legislation ruling animal research in Brazil, comparing it with other countries, as well as fostering bioethical reflection about this issue. For this, we present current Brazilian legislation and we have carried out international literature review and discussion. The articles were searched in PubMed data base, using the key words "bioethics" and "animal welfare". Nineteen articles from 1997 to 2013 were included. It was concluded the evident contribution of animal research for scientific research in several fields. It is morally relevant for humans, as rational beings, to secure humane treatment to animals contributing to research. The safest way to follow this path is establishing clear norms and studies well designed, involving society for assigning ethical norms. Thus, animal welfare would be guarantee.

Obtenção e utilização de imagens de pacientes: proposta de termo de consentimento à luz do direito brasileiro

Ao atender um paciente, muitas vezes o profissional da saúde fotografa ou filma o caso. Há, via de regra, duas razões básicas para tal atitude. A primeira é para a documentação do caso per se, e as imagens ficarão restritas ao prontuário clínico do paciente. E, se porventura algum dia houver um litígio envolvendo aquele determinado tratamento, tais imagens poderão ser utilizadas como meio de prova. A segunda razão diz respeito à divulgação do caso clínico, com a sua publicação em periódicos científicos, apresentação em aulas, cursos, congressos e similares. Pode-se citar ainda uma outra razão: o uso das imagens para a divulgação dos serviços do profissional que conduziu o tratamento/procedimento. Para a obtenção/gravação das imagens, faz-se necessário o consentimento do paciente, ou de seu responsável legal (no caso de incapaz). Porém, a imagem produzida somente poderá ser utilizada para os fins específicos a que se destinou inicialmente. Se porventura o profissional tiver intenção de usá-la, por exemplo, em publicações, precisará do consentimento específico para este fim. Vale lembrar que a própria Constituição Federal da Brasil assegura tal direito. A produção de imagens de pessoas e a sua divulgação em meios acadêmicos, por exemplo, ocorre não somente em atendimentos clínicos, como também em pesquisas que envolvam seres humanos. É necessário respeitar as normas éticas e legais relacionadas ao uso de imagens. Este trabalho apresenta uma proposta de Termo de Consentimento para obtenção e uso de imagens de pacientes de profissionais da saúde.

Responsabilidade do profissional da saúde no esclarecimento equivocado do paciente para obter o seu consentimento livre e esclarecido

Ao paciente é necessário fornecer esclarecimentos sobre as possibilidades terapêuticas, apresentando os riscos, benefícios, prognóstico e custos de cada alternativa possível e indicada. Esta é uma determinação ética e jurídica. Não obstante, o profissional da saúde detém o conhecimento clínico/técnico/científico, e determina quais informações serão (ou não) fornecidas. O paciente decide submeter-se a um tratamento, fornecendo o seu Consentimento Livre e Esclarecido com base nos dados a ele apresentados. Infelizmente, pode ocorrer de alguns profissionais não fornecerem todas as informações necessárias a uma tomada de decisão esclarecida ou, depois de obtido o consentimento do paciente, apresentarem-lhe informação que cause sua desistência do tratamento inicialmente aceito. Esta última informação, se pertinente, e não se tratando de fato superveniente, deveria ter sido fornecida inicialmente. Porém, a informação pode não ser de todo verdadeira, e levar o paciente a decidir baseado, por exemplo, em riscos apresentados e mensurados de forma equivocada. A reabilitação crânio-facial da Articulação Têmporo-Mandibular (ATM), por meio de prótese de ATM, é indicada em muitas situações. Amiúde, pacientes que necessitam de tais próteses apresentam problemas funcionais e estéticos; a expectativa gerada com a reabilitação é grande. Este trabalho apresenta um caso e discute questões éticas e legais, incluindo a responsabilidade civil, do fornecimento parcial e inadequado de esclarecimentos a um paciente.

Estimativa da altura por dimensões dentárias: uma revisão da literatura

The knowledge of Forensic Anthropology is very importance in cases of identification of human remains. One phase of this process is the study of human height, which can be accomplished with relative ease when intact corpses, complete skeletons or long bones are available. However, the experience of Forensic Dentistry is essential in situations in which there is only information of the skull or of the teeth. The objective of this study was to review in the literature and evaluate works concerning the estimate of the height calculated from dental dimensions. Carrea, in 1920, proposed the estimation of the probable height of an individual by developing formulas for maximum and minimum heights from measurements of the lower central and lateral incisors and canines. The method was used in the case "Josef Mengele", to complement estimates. Tested in the Brazilian population, 70% of match between the actual and the estimated stature were obtained. Using more precise instruments, in the modified method, 96% of correct matching were verified. Recently, a new formula was introduced to estimate height, from measurements of upper teeth, because the technique cannot be used when jaw is not available. The correlation between height and dental dimensions is demonstrated. However, there is still a lack in scientific literature in this field, and further studies are necessary. The estimate of height from dental dimensions can be very useful and important, especially in situations where the complete skeleton it not found, and long bones are not available.