Interdisciplinary approach to treat dyskeratosis congenita associated with severe aplastic anemia: A case report

This paper reports on a 4-year-old male who had dyskeratosis congenita and who acquired severe aplastic anemia. The patient developed hyperpigmentation of the face, neck and chest region, arms, shoulders and legs. In addition, he had dry skin, deformed fingernails and toenails, sparse hair and eyebrows and hyperkeratosis of the dorsum of the hands and feet. Laboratory and histological analysis revealed severe pancytopenia and dyserythropoiesis of red blood cells, hypocellularity of white blood cells and decreased megakaryocytes with dysplasia. The intraoral examination identified bleeding gums; petechiae of the palate, tongue and cheek mucosa; and an atrophic, smooth and shining dorsal surface of the tongue. There were deep carious lesions in the deciduous mandibular molars and maxillary anterior teeth; as well as mobility of mandibular left canine, which had bone loss. The treatment for oral lesions included diet changes, improved oral hygiene, and extraction of the deciduous teeth destroyed by caries.

Regional hydroclimatic variability and Brazil's 2001 energy crisis

Purpose - This paper seeks to address the issue of persistent and widespread drought conditions during 2000 and 2001, which were the apparent cause of the decline of water levels in the reservoirs of Brazilian hydroelectric power plants. Design/methodology/approach - This issue is addressed here through a case study of the hydroclimatology of the Paraíba river basin, in Southeast Brazil, home to four large multi-purpose operational reservoirs. Findings - The data analysis shows that neither changes in the frequency nor magnitude of extreme hydrological events (droughts and floods) nor in annual rainfall amounts can be detected from the existing climate record. The explanation is consistent with the fact that the terrestrial water and energy cycles are tightly, and non-linearly, coupled through evapotranspiration. Research limitations/implications - Therefore small change in the seasonality of rainfall can have a significant impact on the basin's overall hydrologic regime, and thus on the availability of water resources. Originality/value - Often, adaptation and resilience to climate variability are discussed in the context of catastrophic events such as floods and droughts. This study suggests that a different type of impacts, those associated with subtle, yet persistent changes of seasonality in the terrestrial water cycle, cannot be ignored in studies of long-term sustainability of water resources. © Emerald Group Publishing Limited.

Panorama de la Inserción Internacional de América Latina y el Caribe 2008-2009: crisis y espacios de cooperación regional

Incluye Bibliografía

Latin America and the Caribbean in the World Economy 2008-2009: Crisis and opportunities for regional cooperation

Incluye Bibliografía

Panorama de la Inserción Internacional de América Latina y el Caribe 2009-2010: crisis originada en el centro y recuperación impulsada por las economías emergentes

Incluye Bibliografía

Latin America and the Caribbean in the World Economy 2009-2010: A crisis generated in the centre and a recovery driven by the emerging economies

Incluye Bibliografía

Panorama de la Inserción Internacional de América Latina y el Caribe 2011-2012: crisis duradera en el centro y nuevas oportunidades para las economías en desarrollo

Incluye Bibliografía

Latin America and the Caribbean in the World Economy 2011-2012: Continuing crisis in the centre and new opportunities for developing economies

Includes bibliography

Desarrollo, crisis y equidad en América Latina

Incluye Bibliografía

Reformas para la cohesión social en América Latina: panorama antes de la crisis

Incluye Bibliografía

Espacios iberoamericanos: Iberoamérica frente a la crisis

Incluye Bibliografía

La Argentina ante la nueva internacionalización de la producción: crisis y oportunidades

Incluye Bibliografía

El desarrollo en América Latina después de la crisis financiera de 2008

Incluye bibliografía

Crisis financieras en países 'exitosos'

Incluye Bibliografía

Corea y Taiwán ante la crisis financiera asiática

Incluye Bibliografía