Introdução a acidentes com produtos químicos [unidade 08]

O Curso de Capacitação a Distância em Saúde, Desastres e Desenvolvimento do IESC/UFRJ tem um enfoque teórico-prático. A estratégia pedagógica escolhida para o curso se baseia na associação de textos teóricos com o estudo de casos. Visa oferecer conhecimentos e ferramentas que permitam formular e implementar planos e programas de redução do risco de desastres, assim como proporcionar ao profissional que atua em desastres uma visão mais ampla de atuação e das conseqüências de um desastre. Pretende-se que o aluno Entenda as responsabilidades do Setor Saúde em situações de desastres, e fortaleça sua capacidade técnica, especialmente nos âmbitos municipal e estadual frente a uma demanda crescente desses eventos.

Gestão de Acidentes com Produtos Químicos: Prevenção e Preparação [unidade 09]

O Curso de Capacitação a Distância em Saúde, Desastres e Desenvolvimento do IESC/UFRJ tem um enfoque teórico-prático. A estratégia pedagógica escolhida para o curso se baseia na associação de textos teóricos com o estudo de casos. Visa oferecer conhecimentos e ferramentas que permitam formular e implementar planos e programas de redução do risco de desastres, assim como proporcionar ao profissional que atua em desastres uma visão mais ampla de atuação e das conseqüências de um desastre. Pretende-se que o aluno Entenda as responsabilidades do Setor Saúde em situações de desastres, e fortaleça sua capacidade técnica, especialmente nos âmbitos municipal e estadual frente a uma demanda crescente desses eventos.

Gestão de acidentes com produtos químicos (APQ): resposta

A Unidade 03 do módulo 02 do Curso de Capacitação a Distância em Saúde, Desastres e Desenvolvimento do IESC/UFRJ é a última unidade deste módulo e abordará as ações de resposta aos acidentes com produtos químicos (APQ) e o papel do setor de saúde nestas ações.

Gestão de Acidentes com produtos químicos: Resposta [unidade 10]

O Curso de Capacitação a Distância em Saúde, Desastres e Desenvolvimento do IESC/UFRJ tem um enfoque teórico-prático. A estratégia pedagógica escolhida para o curso se baseia na associação de textos teóricos com o estudo de casos. Visa oferecer conhecimentos e ferramentas que permitam formular e implementar planos e programas de redução do risco de desastres, assim como proporcionar ao profissional que atua em desastres uma visão mais ampla de atuação e das conseqüências de um desastre. Pretende-se que o aluno Entenda as responsabilidades do Setor Saúde em situações de desastres, e fortaleça sua capacidade técnica, especialmente nos âmbitos municipal e estadual frente a uma demanda crescente desses eventos.

O desenvolvimento do texto dissertativo em crianças da 4ª série

This reaserch analysed the developmental stage of fourth grade (primary school) children in ability of writting argumentative texts joint with their context. The reason of this reaserch is the lack of new studies in linguistical area and high ratio of unable students to make this kind of text. It will be showed the analysis of making text by public schools children for three months. These data were analysed trying identify argumentative operators, the kinds of arguments used and the stage of the argumentative ability of these children. The study showed that the introduction of argumentative text in first grades give them more chances of succeed, preparing these pupils in their finishing high school. This fact obviously will make easier the development of their critical point of view, helping the students to think about their living social reality.

Polímeros biomiméticos em química analítica. Parte 2: aplicações de MIP (Molecularly Imprinted Polymers) no desenvolvimento de sensores químicos

The aim of this paper is the description of the strategies and advances in the use of MIP in the development of chemical sensors. MIP has been considered an emerging technology, which allows the synthesis of materials that can mimic some highly specific natural receptors such as antibodies and enzymes. In recent years a great number of publications have demonstrated a growth in their use as sensing phases in the construction of sensors . Thus, the MIP technology became very attractive as a promising analytical tool for the development of sensors.

Espectroscopia de Ressonância Magnética Nuclear de 13C no estudo de rotas biossintéticas de produtos naturais

During the last five decades, as a result of an interaction between natural product chemistry, synthetic organic chemistry, molecular biology and spectroscopy, scientists reached an extraordinary level of comprehension about the natural processes by which living organisms build up complex molecules. In this context, 13C nuclear magnetic resonance spectroscopy, allied with isotopic labeling, played a determinant role. Nowadays, the widespread use of modern NMR techniques allows an even more detailed picture of the biochemical steps by accurate manipulation of the atomic nuclei. This article focuses on the development of such techniques and their impact on biosynthetic studies.

Ecomateriais: desenvolvimento e aplicação de materiais porosos funcionais para proteção ambiental

Fundamental aspects of the conception and applications of ecomaterials, in particular porous materials in the perspective of green chemistry are discussed in this paper. General recommendations for description and classification of porous materials are reviewed briefly. By way of illustration, some case studies of materials design and applications in pollution detection and remediation are described. It is shown here how different materials developed by our groups, such as porous glasses, ecomaterials from biomass and anionic clays were programmed to perform specific functions. A discussion of the present and future of ecomaterials in green chemistry is presented along with important key goals.

Contaminação de produtos de higiene e cosméticos por n-nitrosaminas

N-nitrosamines are carcinogenic compounds that have been found during the last three decades in a variety of consumer products, including cosmetic and personal care products, and their raw materials. These compounds are formed from amine precursors and nitrosating agents present in the formulations. This paper reviews the formation and occurrence of N-nitrosamines in cosmetic products, as well as presents considerations about analytical, toxicological and regulatory aspects.

Desenvolvimento e caracterização de nanocápsulas de poli (L-lactídeo) contendo benzocaína

In this paper we describe the preparation poly (L-lactide) (PLA) nanocapsules as a drug delivery system for the local anesthetic benzocaine. The characterization and in vitro release properties of the system were investigated. The characterization results showed a polydispersity index of 0.14, an average diameter of 190.1± 3 nm, zeta potential of -38.5 mV and an entrapment efficiency of 73%. The release profile of Benzocaine loaded in PLA nanocapsules showed a significant different behavior than that of the pure anesthetic in solution. This study is important to characterize a drug release system using benzocaine for application in pain treatment.

Definição de shelf life para produtos químicos: a importância de um guia de estabilidade específico para o segmento

The chemical industries worldwide are passing through a very particular moment of re-adaptation due to the implementation of an European regulation called, Registration, Evaluation, Authorization and Restriction of Chemicals (REACH). In Brazil, the Brazilian Chemical Industry needs urgently a specific guide of chemical products stability. The main purpose of this work is to present a proposal of a guide of stability for chemical products based on the reference guides of the International Conference on Harmonization (ICH). Thus, this work proposes an innovation in terms of methodology which will be useful for shelf life definition purpose for chemical industry products.

Desenvolvimento de um algoritmo para identificação e correção de spikes em espectroscopia Raman de imagem

Raman imaging spectroscopy is a highly useful analytical tool that provides spatial and spectral information on a sample. However, CCD detectors used in dispersive instruments present the drawback of being sensitive to cosmic rays, giving rise to spikes in Raman spectra. Spikes influence variance structures and must be removed prior to the use of multivariate techniques. A new algorithm for correction of spikes in Raman imaging was developed using an approach based on comparison of nearest neighbor pixels. The algorithm showed characteristics including simplicity, rapidity, selectivity and high quality in spike removal from hyperspectral images.

Desenvolvimento, produção e caracterização de nanocristais de fármacos pouco solúveis

Poorly soluble drugs have low bioavailability, representing a major challenge for the pharmaceutical industry. Processing drugs into the nanosized range changes their physical properties, and these are being used in pharmaceutics to develop innovative formulations known as Nanocrystals. Use of nanocrystals to overcome the problem of low bioavailability, and their production using different techniques such as microfluidization or high pressure homogenization, was reviewed in this paper. Examples of drugs, cosmetics and nutraceutical ingredients were also discussed. These technologies are well established in the pharmaceutical industry and are approved by the Food and Drug Administration.

Desenvolvimento e validação de método espectrofotométrico para determinação de corante à base de luteína adicionado em iogurte desnatado

A simple analytical method for extraction and quantification of lutein colorant added to yogurt was developed and validated. The method allowed complete extraction of carotenoids using tetrahydrofuran in vortex, followed by centrifugation, partition to diethyl ether/petroleum ether, and drying. The carotenoids dissolved in ethanol were quantified by UV-Vis spectrophotometry. This method showed linearity in the range tested (1.41-13.42 µg g-1), limits of detection and quantification of 0.42 and 1.28 µg g-1, respectively, low relative standard deviation (3.4%) and recovery ranging from 95 to 103%. The method proved reliable for quantification of lutein added to yogurt.

Guia para a determinação da estabilidade de produtos químicos

Companies worldwide are reviewing their working process to avoid waste, become aligned with environmental management standards and to fulfill specifications defined for national and international regulations. In this context, it is important that Brazilian Chemical companies have a specific stability guide for their products. The main purpose of this work is to present a stability guide for chemical products based on the existing guides of the Pharmaceutical and Cosmetics segments. Furthermore, this work proposes to offer an additional period of shelf life for chemical products, provided they meet certain prerequisites.