Deletion of Epstein-Barr virus latent membrane protein 1 gene in United States and Brazilian Hodgkin's disease and reactive lymphoid tissue: High frequency of a 30-bp deletion

A 30-basepair (bp) deletion in the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) gene has been reported in nasopharyngeal carcinoma and EBV-associated malignant lymphomas. Prior studies have found the deletion in about 10% to 28% of cases of Hodgkin's disease (HD), particularly in cases with aggressive histology. We studied the prevalence of 30-bp LMP1 gene deletion in EBV-positive HD in the United States (US) (12 cases) and Brazil (26 cases) with comparison to reactive lymphoid tissues (21 cases) and HD without EBV-positive Reed-Sternberg cells (15 cases). We studied the status of the LMP1 gene by Southern blot hybridization of polymerase chain reaction (PCR) products obtained after amplification with primers spanning the site of the deletion. We also performed EBV typing, EBER1 in situ hybridization, and LMP1 protein immunohistochemistry. EBV was detected in 12/26 (46%) cases of HD from the US and 26/27 (96%) cases of Brazilian HD. The 30-bp LMP1 gene deletion was observed in 4/12 (33%) cases of EBV-positive HD from US, and 12/26 (46%) cases of Brazilian EBV-positive HD, including 3 cases of type B EBV, as compared with 12/21 (57%) reactive lymphoid tissues and 9/15 (60%) cases of EBV-negative HD. US and Brazilian HD showed a higher prevalence of the 30-bp LMP1 gene deletion, compared with studies of others. The unexpected finding of high incidence of 30-bp deletion in LMP1 gene in reactive lymphoid tissue and HD without EBV-positive Reed-Sternberg cells suggests that this deletion may not be relevant to HD pathogenesis in most cases. Copyright (C) 1997 by W.B. Saunders Company.

FIRE ANT MOUND DENSITIES IN THE UNITED-STATES AND BRAZIL (HYMENOPTERA, FORMICIDAE)

To compare fire ant populations (Solenopsis) in North and South America, we surveyed 102 preselected roadside sites, half in the southeastern United States and half in the state of Mato Grosso do Sul, Brazil. Fire ants were considerably more abundant in the United States. They occurred at more sites (100 versus 70%), in higher densities (170 versus 30 mounds/ha), in larger mounds (27.0 versus 13.8 liters), and they constituted a larger fraction of the local ant community (97 versus 13% of occupied baits). These data are consistent with the hypothesis that North American populations of S. invicta have escaped natural biological control; however, cultural and climatic factors are also likely explanations.

The megalopa stage of Portunus spinimanus Latreille, 1819 and Portunus gibbesii (Stimpson, 1859) (Decapoda, Brachyura, Portunidae) from the southeastern Atlantic coast of the United States

The identification of megalopae from plankton samples is difficult, because this larval stage is the least well known among crab larvae, unknown in some species and poorly described in others. Wild megalopa specimens of some swimming crabs (family Portunidae Rafinesque, 1815) were captured alive from neuston samples obtained during summer surveys near the coast of Charleston, South Carolina (U.S.A). For identification purposes, larvae were reared to the 8th juvenile instar. After reaching the 5th juvenile instar, the juvenile crabs exhibited morphological features suitable for identification to the species level. The specimens belonged to two species of Portunidae, Portunus spinimanus Latreille, 1819 and P. gibbesii (Stimpson, 1859). Their megalopae were described in detail and compared to other portunid megalopae known from the southeastern Atlantic coast of the U.S.A. Species-specific characters of portunid megalopae are the number of carpal spines on the chelipeds, the relative size of the sternal spines (7th sternite), the number of antennal flagellum segments, and the setation of mouthparts. Copyright © 2007 Magnolia Press.

Economic relations of Brazil and the United States and the Enterprise for the Americas Initiative

Includes bibliography

The social roots of United States protectionism

Includes bibliography

A collection of documents on economic relations between the United States and Central America, 1906-1956

Includes bibliography

The global context and the renewal of the United Nations = El contexto global y la renovación de Naciones Unidas

Introducción En esta época posterior a la guerra fría y de creciente globalización, el rol de las Naciones Unidas experimenta constantes redefiniciones y desafíos. El señor Kofi Annan, Secretario General, afirmó que las Naciones Unidas se encuentran hoy en una encrucijada, y que el momento es tan trascendente como lo fue el de su fundación, hace sesenta años. Aunque los principios fundamentales de la democracia, los derechos humanos y el estado de derecho siguen siendo universalmente aceptados y se consideran piedra angular del orden mundial, el Secretario General considera, como otros muchos, que ha llegado el momento de rediseñar su estructura básica para combinar el imperativo de la acción con la necesidad de legitimidad". En este contexto, durante la visita oficial del Secretario General a Chile en noviembre del 2003, la Comisión Económica para América Latina y el Caribe (CEPAL) fue anfitriona de la mesa redonda "El contexto global y la renovación de las Naciones Unidas", en la que participaron la señora Tarja Halonen, Presidenta de la República de Finlandia, el señor Ricardo Lagos, Presidente de la República de Chile, y el señor Annan. Entre los invitados a este acto se encontraban miembros del cuerpo diplomático en Santiago de Chile, destacados intelectuales, representantes de la sociedad civil y académicos que enriquecieron el debate con preguntas y comentarios. Los tres líderes analizaron la situación política, económica y social del mundo de hoy en el contexto del actual proceso de reforma de las Naciones Unidas. Disertaron sobre los desafíos del desarrollo, el multilateralismo, la interdependencia de los países y su necesidad de contar con una participación ciudadana creciente y coherente en los planos local, regional y mundial. Uno de los temas centrales fue el poder, y el modo en que las Naciones Unidas pueden canalizarlo y redistribuirlo con el fin de que su ejercicio sea colectivo y civilizado. Aunque es imposible resolver en una mañana o en una sola reunión estos complejos asuntos, que en ocasiones resultan abrumadores, tenemos la esperanza de que este libro proporcione inspiración, conceptos e ideas que permitan alcanzar soluciones eficaces e innovadoras en el futuro. José Luis Machinea Secretario Ejecutivo CEPAL"

The United States and Latin America and the Caribbean: Highlights of economics and trade

Foreword by Alicia Bárcena

The United Nations Regional Commissions: Enhancing Capacities To Eradicate Violence Against Women

This study captures the significant regional and national knowledge that has been accumulated on measuring violence against women through the interregional project "Enhancing capacities to eradicate violence against women through networking of local knowledge communities". Supported by the United Nations Development Account, this two-year project was coordinated by the Economic Commission for Latin America and the Caribbean (ECLAC), through its Division for Gender Affairs, and implemented by the five regional commissions of the United Nations, in cooperation with the United Nations Statistical Division and UN-Women. Through the project, more than 30 countries worldwide have been engaged in the development, dissemination and testing of core indicators endorsed by the United Nations Statistical Commission. This process has made a decisive contribution to designing and building consensus around a common methodology to measure and document violence against women. Furthermore, the inclusion of all five regions in piloting the newly-developed tools to measure violence has also ensured that these tools capture a more comprehensive and complex vision of violence as experienced by women across cultures and regions. This report presents an overview of the activities that have taken place in the five regions, and outlines the key outcomes and lessons learned. Through its activities, the interregional project has made the cumulative body of existing knowledge in terms of policies, findings, innovative practices, processes and statistical data available to policymakers, activists and women's organizations. New knowledge was also produced through national studies that examined underexplored sources of data on violence against women. National capacities to collect information on violence against women through official statistics were strengthened through targeted training activities as well as through participation in expert meetings which provided the space for an effective exchange of best practices.

Sustainable Development in Latin America and the Caribbean. Follow-up to the United Nations development agenda beyond 2015 and to Rio+20

Includes bibliography

Towards a new international financial architecture: report of the Task Force of the Executive Committee on Economic and Social Affairs of the United Nations, 21 January 1999 = Hacia una nueva arquitectura financiera internacional: informe del Grupo de Trabajo del Comité Ejecutivo de Asuntos Económicos y Sociales de las Naciones Unidas, 21 de enero de 1999

Publicación bilingüe

Some considerations on the possible effects of the failure of the United States Congress to renew the ATPDEA

Includes bibliography