Desenvolvimento e caracterização de sistemas nanoestruturados para administração cutânea de metotrexato

A psoríase é uma doença inflamatória de pele e das articulações, e por acometer um órgão visível como a pele, resulta em transtornos psicológicos relacionados à auto-estima do paciente. Dentre os fármacos empregados no tratamento, destaca-se o metotrexato para uso sistêmico que, embora eficiente, possui a desvantagem de causar efeitos colaterais tóxicos como a hepatotoxicidade e a mielotoxicidade. Para minimizar tais efeitos e aumentar a eficácia do fármaco, o trabalho teve por objetivo desenvolver e caracterizar sistemas nanoestruturados para administração cutânea do metotrexato. Para realizar esse estudo, inicialmente foram preparadas diferentes formulações constituídas por silicone fluido de copolímero glicol (DC® 193), poliéter funcional siloxano (DC® 5329) e água destilada. O metotrexato foi incorporado numa concentração de 1,25% (p/v), com auxílio de solução de hidróxido de sódio 1M, sendo ajustado o pH final da formulação para 7,0 com ácido clorídrico 0,1M. Foram selecionadas algumas regiões do diagrama para serem submetidas a testes de estabilidade, empregando o teste de centrifugação, determinação do pH, condutividade iônica, índice de refração e avaliação das características organolépticas. Foi realizada a análise reológica empregando reômetro, modelo RS-1 (HaakeRheostress). As estruturas das formulações foram analisadas por microscopia de luz polarizada. As amostras com maior concentração de tensoativo apresentaram aspecto transparente, sendo submetidas à análise com microscópio de luz polarizada, onde evidenciou-se estruturas conhecidas como “cruzes de malta”, indicativas de fase lamelar. Foram selecionadas 3 formulações com concentração de 40% de tensoativo, variando-se as proporções de água e óleo, nas quais foram incorporadas o metotrexato... (Resumo completo, clicar acesso eletrônico abaixo)

A construção da autonomia numa perspectiva piagetiana: contribuições para a Educação Infantil

This paper aims at discussion the construction of autonomy of cognitive development and child morality, according to the Piagetian approach view of the influence of socio-moral classroom in kindergarten. It is known that education is a very important part of participation in relation to the development of autonomy by the child, especially when it comes to kindergarten who becomes responsible for performing the initial encouragement of this ability, respecting the phase cognitive development in which the child is. We focus, therefore, the need for education and teaching activities that enable this construction offering little opportunity to exercise and build their first signs of autonomy. For their achievement, in addition to literature, which has been supported by theoretical studies of Jean Piaget, we chose a field research where we look, from the interview and observation, investigate the socio-moral environment of a room class of a school Kindergarten, highlighting the important opportunities for the exercise of autonomy for the children, amid the routine of the group. The interview was focused on the pursuit of basic knowledge of the educator on the subject, as well as what would be aware of the role of preschool in the process of moral development and about their own role as an educator this mode of education. Since the remark was directed at the teacher's procedures against the encouragement of social and moral ability, focusing mainly on interpersonal relationships in the classroom. Our classroom has proved to be a cooperative environment and therefore we emphasize the importance of the teacher's conduct that permeated the day-to-day classroom and encouraged to start building this skill by the student. The main objective of this study therefore was to investigate the possibilities and outcomes that have a school experience for the development of autonomy for children

Financiamento e convênios na educação infantil: uma análise a partir de periódicos nacionais

This study is bound to the “Research and Studies in Educational Policies”, GREPPE (interinstitutional group) – Rio Claro Section, more accurately to the Research Project entitled Evaluating the scientific production about financing and agreements in childhood education, coordinate by Prof. Dr. Regiane Helena Bertagna, that has as main objective to survey of scientific production at the national level related to the theme of financing and agreements in childhood education in the period from 2000 to 2010. This research has as objective to analyze the financing of childhood education examinee issues of educational policies related to this aspect in this stage of the basic education in national journals. It is intended to ascertain the discussion held in the articles about childhood education financing highlighting the strategies used by the government to offer treatment to the childhood education by means of agreements, or even, by means of public-private partnerships. For the development of this research will be conducted a survey and data analysis from journals of the “Coordination of Improvement of Senior Staff” (CAPES) classified as A2 in the evaluation of 2008. The research will make a cutting between the years from 2000 to 2010; will be analyzed only the national journals online available and that adress the thematic studied

Desenvolvimento de um equipamento para análise de desgastes em prótese de articulação total de quadril

Pós-graduação em Engenharia Mecânica - FEG

Análise microbiológica e parasitológica de alimentos servidos em escolas do ensino infantil e fundamental de uma cidade da região de São José do Rio Preto - SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Educação literária na educação infantil: o livro nas mãos de professoras e educadoras de Araçatuba (SP)

Pós-graduação em Educação - FCT

Avaliação comparativa em educação e música entre crianças precoces com comportamento de superprodução e crianças com desenvolvimento típico

Pós-graduação em Educação - FFC

Percepções de professoras de escolade públicas eucação infantil acerca de sua formação e prática educativa: o caso de Medianeira - PR

Pós-graduação em Educação - FFC

Organização e funcionamento do atendimento educacional especializado na educação infantil: estudo de caso

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Caracterização de práticas de governança territorial no processo de desenvolvimento contemporâneo em Timor-Leste: análise a partir da questão da formação profissionalizante

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

As diretrizes curriculares nacionais da educação infantil: em busca de um trabalho pedagógico com qualidade

Since when nurseries and pre-schools were established to serve educationally Brazilian children by Federal Constitution of 1988, advances were taken up claiming the improvement of early childhood education, such as raising the professional training, transfer of funds, construction of schools, as well as legal provisions have been drafted to guide and define the pedagogical practices of early childhood education. This paper intends to discuss the National Curriculum Guidelines for Early Childhood Education, which define how they should be organized teaching practice, and examine how the activities should be developed in early childhood education institutions, to objectify the holistic development of children in seeking quality care this stage of basic education.

Educação inclusiva na educação infantil

This paper aims to trigger a reflection on inclusive education in early childhood education, considering education as an inclusive educational model endorsed by public policies, but still far from school reality. The reflection aims to think about necessary changes since early childhood education,because this is the first stage of basic education and it is a critical period in development and learning process of children with disabilities. The construction of the inclusive school since early childhood education involves thinking about its space, time, professional, educational resources etc..,turning to the possible access, retention and development to students with disabilities, students that, because of their particular characteristics, have a special educational necessity. The text discusses, among other things, the necessity to rethink pedagogical practice as a key of school inclusion in early childhood education. The inclusive pedagogical practice should be constituted by the junction of the acquired knowledge by the teacher throughout his career and by the availability to seek new ways to do it considering students diversity and their individual characteristics.

Forma e conteúdo do ensino na educação infantil: o papel do jogo protagonizado e as contribuições da literatura infantil

This paper approaches the relation between school education and psychic development in the light of cultural-historical theory and critical-historical pedagogy, discussing the triad form-content-receiver of teaching in the context of early childhood education. Considering the goal of developing the bases of theoretical thinking in children, the paper analyses role-play as leading activity in preschool and explores the contributions of child literature, highlighting the importance of providing access to artistic works which depict reality in an imaginative form as multisided and in permanent movement.

Manifestações da sexualidade infantil: percepção de pais e professoras de crianças de 0 a 6 anos

This article presents a descriptive-qualitative study aimed at investigating the perception of seven teachers, 5 parents and 18 mothers about the sexual expression of children until 6 years old, through a questionnaire with semi-open questions for content analysis. The sexual behavior identified by adults at home or school refers mainly to gender issues and the discovery of the body: the children reproduce conceptions of masculine and feminine, they manipulate their own bodies or that of others, and they talk about dating, kissing in the mouth and sex. The teachers have a higher perception of the children’s sexual behaviors than their parents at home, because they are more explicit in school. Teachers report that the observed behaviors cause anxiety and discomfort, while the parents report that they usually talk with their children about the theme. In general, there are reports of little knowledge about how to deal with children’s sexual manifestations: for teachers, who have little academic training in the area of sexuality, and for the family, who show some personal and moral difficulties. It was concluded that participants understand children as having sexuality because they perceive different expressions of infant sexuality that are typical in the development. It is necessary to invest in teachers’ academic and continuing education in early childhood, and in a joint work with family and school, in search of a positive experience of an emancipatory sexual education for children.

Concepções e práticas de ensino na educação infantil: psicologia e educação

The general objective of this work is to analyze the conceptions of teaching and learning of kindergarten teachers use in their teaching practices and resources they adopt to work the subjects with the children. As a starting point for the research we considered the assumption that the teaching activities of teachers were supported by some principles of the psychogenetic paradigm, the theoretical basis of the constructivist pedagogical movement. However, by means of the observations and analysis carried out, our hypothesis was not consolidated because the practices of teachers and their conceptions of learning differ from the constructivist perspective announced. What can be concluded is that these teachers understand their role and the role of the school, more specifically the processes of teaching, as something that actually promotes the intellectual development of children effectively.