Sustainable drugs and global health care

Each day, Earth's finite resources are being depleted for energy, for material goods, for transportation, for housing, and for drugs. As we evolve scientifically and technologically, and as the population of the world rapidly approaches 7 billion and beyond, among the many issues with which we are faced is the continued availability of drugs for future global health care. Medicinal agents are primarily derived from two sources, synthetic and natural, or in some cases, as semi-synthetic compounds, a mixture of the two. For the developed world, efforts have been initiated to make drug production "greener", with milder reagents, shorter reaction times, and more efficient processing, thereby using less energy, and reactions which are more atom efficient, and generate fewer by-products. However, most of the world's population uses plants, in either crude or extract form, for their primary health care. There is relatively little discussion as yet, about the long term effects of the current, non-sustainable harvesting methods for medicinal plants from the wild, which are depleting these critical resources without concurrent initiatives to commercialize their cultivation. To meet future public health care needs, a paradigm shift is required in order to adopt new approaches using contemporary technology which will result in drugs being regarded as a sustainable commodity, irrespective of their source. In this presentation, several approaches to enhancing and sustaining the availability of drugs, both synthetic and natural, will be discussed, including the use of vegetables as chemical reagents, and the deployment of integrated strategies involving information systems, biotechnology, nanotechnology, and detection techniques for the development of medicinal plants with enhanced levels of bioactive agents.

Discriminação entre estádios de maturação e tipos de processamento de pós-colheita de cafés arábica por microextração em fase sólida e análise de componentes principais

A fruit chemical composition reflects its maturation stage. For coffee, it is also the reflex of the post-harvesting processing type, dry, semi-wet and wet. The object of this work was to verify if headspace solid phase microextraction coupled to gas chromatography (HS-SPME-GC) could be used to discriminate between samples harvested in different maturation stages and treated by different processes. With application of principal component analysis to the area of 117 compounds extracted by SPME, using divinylbenzene/Carboxen/polydimethylsiloxane fiber, it was possible to discriminate, in the roasted and ground coffee, the maturity stage and processing type used .

Kokopuuhakkeen korjuukustannukset nuorista metsistä eri menetelmillä

Seloste artikkelista: Harvesting technology and the cost of the fuel chips from early thinnings. Silva Fennica 42 (2008) : 2, s. 267-283.

Modelling mean above and below ground litter production based on yield tables

Selective papers of the workshop on "Development of models and forest soil surveys for monitoring of soil carbon", Koli, Finland, April 5-9 2006.

RFID-teknologian hyödyntäminen puolustusvoimien yksilöseurattavan materiaalin hallinnassa - CASE: maavoimat, Karjalan Prikaati

RFID-teknologian käyttöönotto on vakaassa kasvussa ja kiinnostus tekniikan soveltami-seen on erityisesti yksilöseurannan alueella. Diplomityössä on tutkittu RFID -teknologian mahdollisuuksia puolustusvoimien normaaliolojen kriittisen yksilöseurattavan materiaalin hallintaan. Case-joukko-osastona tutkimuksessa on toiminut Karjalan Prikaati. Tutkimus-aihetta on tarkasteltu prosessiajattelun näkökulmasta, mutta myös tiedon keräämistä on käsitelty. RFID-pohjainen tieto eroaa perinteisellä tavalla kerätystä tiedosta. RFID-teknologian hyödyntäminen tarjoaa kuitenkin entistä monipuolisemman ja virheettö-mämmän tiedon keräämisen reaaliajassa, joten se tukee hyvin prosessimaista toimintaa. Tutkimuksen painopisteenä on ollut logistiikan resurssien käytön tehostaminen RFID-teknologiaan tukeutuvan prosessimaisen toiminnan kautta. Tehokas prosessimainen toi-minta soveltuu hyvin sotilasorganisaatioihin. Prosessien määrittely ja kuvaaminen autta-vat tunnistamaan niissä ilmeneviä ongelmia ja samalla kuvaamaan mahdollisten muutos-ten vaikutukset prosesseihin sekä organisaatioihin. Perusteet prosessien uudelleen suun-nittelulle lähtevät prosessimaisen toiminnan tunnistamisesta ja kuvaamisesta. Case-joukko-osaston nykytilan kartoituksessa havaittiin, että joukko-osastotasolta on tähän asti puuttunut kokonaisvaltainen prosessimainen toimintatapa. Nykytila-analyysin pohjalta tutkimustyössä rakennettiin yksilöseurattavan materiaalin käsittelyä kuvaava toimintaprosessi, joka muodostui kuudesta eri osaprosessista. Tutki-mustyölle valitun painopisteen mukaisesti osaprosesseista viisi liittyi logistiikkaan ja kun-nossapitoon yksi. Tämän jälkeen keskityttiin tutkiman RFID-tekniikan avulla saavutetta-via keskeisiä hyötyjä. RFID-teknologian ja prosessimaisen toiminnan avulla joukko-osastotasolla on saavutettavissa useita hyötyjä verrattuna nykytilan toimintaan. Uudessa toimintatavassa keskeisiä tunnistettuja hyötyjä ovat toiminnan automatisoituminen, teho-kas tiedonkeruu, toiminnan hyvä laatu ja tehokkuus. Toiminnan tehokkuutta organisaati-on logistisissa toiminnoissa on siis mahdollista kasvattaa ja samalla lisätä näkyvyyttä toimitusketjun sisälle ja sen eri vaiheisiin. Lisäksi RFID-teknologian käyttöönotolla pys-tytään tukemaan hyvin puolustusvoimien kunnossapidon strategista kumppanuutta.

Effect of forest-based biofuels production on carbon footprint, Case: Integrated LWC paper mill

International energy and climate strategies also set Finland’s commitments to increasing the use of renewable energy sources and reducing greenhouse gas emissions. The target can be achieved by, for example, increasing the use of energy wood. Finland’s forest biomass potential is significant compared with current use. Increased use will change forest management and wood harvesting methods however. The thesis examined the potential for integrated pulp and paper mills to increase bioenergy production. The effects of two bioenergy production technologies on the carbon footprint of an integrated LWC mill were studied at mill level and from the cradle-to-customer approach. The LignoBoost process and FT diesel production were chosen as bioenergy cases. The data for the LignoBoost process were obtained from Metso and for the FT diesel process from Neste Oil. The rest of the information is based on the literature and databases of the KCL-ECO life-cycle computer program and Ecoinvent. In both case studies, the carbon footprint was reduced. From the results, it can be concluded that it is possible to achieve a fossil-fuel-free pulp mill with the LignoBoost process. By using steam from the FT diesel process, the amount of auxiliary fuel can be reduced considerably and the bark boiler can be replaced. With a choice of auxiliary fuels for use in heat production in the paper mill and the production methods for purchased electricity, it is possible to affect the carbon footprints even more in both cases.

Metsäalan yrittäjien tyytyväisyys urakanantajaan

The aim of this thesis is to clarify, how satisfied the harvesting and transport entrepreneurs of Stora Enso Metsä are with the partnership relationship between Stora Enso Metsä and entrepreneurs. The aim is also to found the main areas of development in relation to forest entrepreneur. 161 companies answered to quantitative survey. Based on the results gathered, it would appear that the entrepreneurs are fairly satisfied with the functioning of Stora Enso Metsä. Changes of operations during the past two years is experienced a relatively neutral, although an entrepreneurial model is significantly changed and the model of transportation also. Most obvious targets for development according to the responses are information sharing, feedback, development of systems and IT applications.

Energiapuuta Etelä-Savosta

Energiapuuta Etelä-Savosta hankkeessa tutkittiin ja kehitettiin energiapienpuun mahdollisuuksia osana suurimittakaavaista alueellista hankintaa. Energiapienpuun potentiaali suurimittakaavaisena polttoaineena on lupaava johtuen hyvästä biomassan saatavuudesta ja tarjontahalukkuudesta, korjuun teknologisesta edistyksestä ja logististen ratkaisujen monipuolisuudesta sekä käyttömäärien kasvusta. Hanke kokonaisuus sisälsi seuraavia osatutkimuksia: Etelä-Savon energiatase, metsänomistajakysely, asiantuntijahaastattelu, metsänkasvatussimulointi, metsäpolttoaineiden saatavuuslaskenta, puun kosteuden seurantatutkimus, logistiikan demonstraatioita sekä energiapuun hankintalogistiikan kustannusvertailuja. Hankkeessa käsiteltiin energiapienpuun arvoketjua metsänkasvatuksesta lopputuotteen käyttöön asti. Tutkimuksen tulokset osoittavat, että energiapienpuulla on mahdollisuudet suurimittakaavaisessa hankinnassa, kunhan toimitusketjussa panostetaan tehokkuuden ja laadun jatkuvaan parantamiseen.

Decomposition of corn and soybean residues under field conditions and their role as inoculum source

Necrotrophic parasites of above-ground plant parts survive saprophytically, between growing seasons in host crop residues. In an experiment conducted under field conditions, the time required in months for corn and soybean residues to be completely decomposed was quantified. Residues were laid on the soil surface to simulate no-till farming. Crop debris of the two plant species collected on the harvesting day cut into pieces of 5.0cm-long and a 200g mass was added to nylon mesh bags. At monthly intervals, bags were taken to the laboratory for weighing. Corn residues were decomposed within 37.0 months and those of soybean, within 34.5 months. Hw main necrotrophic fungi diagnosed in the corn residues were Colletotrichum gramicola, Diplodia spp. and Gibberella zeae, and those in soybeans residues were Cercospora kikuchii, Colletotrichum spp, Glomerella sp. and Phomopsis spp. Thus, those periods shoulb be observed in crop rotation aimed at to eliminating contaminated residues and, consequently, the inoculum from the cultivated area.

Web Archiving in Finland. Memorandum for the members of the CDNL

This report describes web archiving in the National Library of Finland. The National Library of Finland has been archiving Finnish web on a regular basis since 2006. Web archiving is an important part of the Library'ʹs endeavours to collect and preserve Finnish published cultural heritage. In 2010, the amount of harvested data was 200 million files, or 25 Terabytes. The report takes the reader through the relevant legislation; internal plans and policies; funding and their allocation; the practices of web archiving; arrangements for the use of the archive; and issues rising from data security, sensitive materials, &c.

Painovoimaisen kemiallisen vesienkäsittelymenetelmän soveltuvuus pienille turvetuotantoalueille

Turvetuotannon suurimpana ympäristövaikutuksena pidetään tuotantoalueiden valuma-vesistä johtuvia ympäristövaikutuksia. Tiukentunut ympäristölainsäädäntö edellyttää uusilta turvetuotantoalueilta parhaan käyttökelpoisen tekniikan käyttöä valumavesien-käsittelyssä. Parhaaksi käyttökelpoiseksi tekniikaksi luetaan pintavalutus- ja kasvilli-suuskentän sekä kemikaloinnin käyttö valumavesien puhdistuksessa. Tämän tutkimuksen tarkoituksena oli selvittää painovoimaisen kemiallisen vesienkäsit-telymenetelmän soveltuvuutta pienille turvetuotantoalueille. Tutkimuskohteena oli Lep-pisuo Luumäen kunnassa, jonne rakennettiin 2010 painovoimaisen kemikaloinnin koe-laitteisto. Laitteiston puhdistustulosta tarkasteltiin kemikalointiin tulevan ja lähtevän veden sekä taustanäytepisteiden tarkkailutulosten avulla. Laitteiston toimivuutta arvioi-tiin kemikaalin annostelun ja toimintavarmuuden avulla. Vuoden 2010 tarkkailutuloksista saatiin keskimääräisiksi erotustehokkuuksiksi koko-naisfosforin osalta 65,2 %, kokonaistypen osalta 28,1 % ja CODMn osalta 65,5 %. Ke-mikaloinnista lähtevän veden kokonaisfosforipitoisuus oli 7,7 μg/l, kokonaistyppipitoi-suus 656 μg/l ja CODMn 5,5 mg/l O2. Ferrisulfaatin annostelu oli keskimäärin 81 mg/l, vaihteluvälillä 25–268 mg/l.

Toimintokohtaisen kustannuslaskennan soveltaminen puunkorjuu- ja puunkuljetusoperaatioissa

Seloste artikkelista: Applying the activity-based costing to cut-to-length timber harvesting and trucking / Tuomo Nurminen, Heikki Korpunen & Jori Uusitalo. - Julkaisussa: Silva Fennica 43 (2009) : 5, s. 847-870.

Forest Biomass Resources and Technological Prospects for the Production of Second-generation Biofuels in Finland by 2020

Introduction of second-generation biofuels is an essential factor for meeting the EU’s 2020 targets for renewable energy in the transport sector and enabling the more ambitious targets for 2030. Finland’s forest industry is strongly involved in the development and commercialising of second-generation biofuel production technologies. The goal of this paper is to provide a quantified insight into Finnish prospects for reaching the 2020 national renewable energy targets and concurrently becoming a large-scale producer of forest biomass based second-generation biofuels feeding the increasing demand in European markets. The focus of the paper is on assessing the potential for utilising forest biomass for liquid biofuels up to 2020. In addition, technological issues related to the production of second-generation biofuels were reviewed. Finland has good opportunities to realise a scenario to meet 2020 renewable energy targets and for large-scale production of wood based biofuels. In 2020, biofuel production from domestic forest biomass in Finland may reach nearly a million ton (40 PJ). With the existing biofuel production capacity (20 PJ/yr) and national biofuel consumption target (25 PJ) taken into account, the potential net export of biofuels from Finland in 2020 would be 35 PJ, corresponding to 2–3% of European demand. Commercialisation of second-generation biofuel production technologies, high utilisation of the sustainable harvesting potential of Finnish forest biomass, and allocation of a significant proportion of the pulpwood harvesting potential for energy purposes are prerequisites for this scenario. Large-scale import of raw biomass would enable remarkably greater biofuel production than is described in this paper.

Practical Experiences with Ingesting Materials for Long-Term Preservation

The National Library of Finland is responsible for the collection, preservation and accessibility of Finland’s published national heritage, and for its other unique collections. This presentation will give a general overview of the several processes employed in the digitization and handling of electronic legal deposit. METS format has been chosen as the container format for digitized materials, and considerable amount of effort has been put into creating adequate METS profiles. As METS will be heavily relied as a container format, the practicalities are discussed in some depth. Regarding electronic legal deposit, the National Library has concentrated on large-scale web harvesting. Depositing of e-books is being tested with publishers. The future plans concerning digital preservation will be presented, especially the National Digital Library initiative.