947 resultados para SYMBOLIC SUBSTITUTION
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This essay aims to confront the literary text Wuthering Heights by Emily Brontë with five of its screen adaptations and Portuguese subtitles. Owing to the scope of the study, it will necessarily afford merely a bird‘s eye view of the issues and serve as a starting point for further research. Accordingly, the following questions are used as guidelines: What transformations occur in the process of adapting the original text to the screen? Do subtitles update the film dialogues to the target audience‘s cultural and linguistic context? Are subtitles influenced more by oral speech than by written literary discourse? Shouldn‘t subtitles in fact reflect the poetic function prevalent in screen adaptations of literary texts? Rather than attempt to answer these questions, we focus on the objects as phenomena. Our interdisciplinary undertaking clearly involves a semio-pragmatic stance, at this stage trying to avoid theoretical backdrops that may affect our apprehension of the objects as to their qualities, singularities, and conventional traits, based on Lucia Santaella‘s interpretation of Charles S. Peirce‘s phaneroscopy. From an empirical standpoint, we gather features and describe peculiarities, under the presumption that there are substrata in subtitling that point or should point to the literary source text, albeit through the mediation of a film script and a particular cinematic style. Therefore, we consider how the subtitling process may be influenced by the literary intertext, the idiosyncrasies of a particular film adaptation, as well as the socio-cultural context of the subtitler and target audience. First, we isolate one of the novel‘s most poignant scenes – ‗I am Heathcliff‘ – taking into account its symbolic play and significance in relation to character and plot construction. Secondly, we study American, English, French, and Mexican adaptations of the excerpt into film in terms of intersemiotic transformations. Then we analyze differences between the film dialogues and their Portuguese subtitles.
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Coevolution between two antagonistic species has been widely studied theoretically for both ecologically- and genetically-driven Red Queen dynamics. A typical outcome of these systems is an oscillatory behavior causing an endless series of one species adaptation and others counter-adaptation. More recently, a mathematical model combining a three-species food chain system with an adaptive dynamics approach revealed genetically driven chaotic Red Queen coevolution. In the present article, we analyze this mathematical model mainly focusing on the impact of species rates of evolution (mutation rates) in the dynamics. Firstly, we analytically proof the boundedness of the trajectories of the chaotic attractor. The complexity of the coupling between the dynamical variables is quantified using observability indices. By using symbolic dynamics theory, we quantify the complexity of genetically driven Red Queen chaos computing the topological entropy of existing one-dimensional iterated maps using Markov partitions. Co-dimensional two bifurcation diagrams are also built from the period ordering of the orbits of the maps. Then, we study the predictability of the Red Queen chaos, found in narrow regions of mutation rates. To extend the previous analyses, we also computed the likeliness of finding chaos in a given region of the parameter space varying other model parameters simultaneously. Such analyses allowed us to compute a mean predictability measure for the system in the explored region of the parameter space. We found that genetically driven Red Queen chaos, although being restricted to small regions of the analyzed parameter space, might be highly unpredictable.
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We define families of aperiodic words associated to Lorenz knots that arise naturally as syllable permutations of symbolic words corresponding to torus knots. An algorithm to construct symbolic words of satellite Lorenz knots is defined. We prove, subject to the validity of a previous conjecture, that Lorenz knots coded by some of these families of words are hyperbolic, by showing that they are neither satellites nor torus knots and making use of Thurston's theorem. Infinite families of hyperbolic Lorenz knots are generated in this way, to our knowledge, for the first time. The techniques used can be generalized to study other families of Lorenz knots.
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Mestre em Engenharia Civil - Especialização em Estruturas
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A fourteen year schistosomiasis control program in Peri-Peri (Capim Branco, MG) reduced prevalence from 43.5 to 4.4%; incidence from 19.0 to 2.9%, the geometric mean of the number of eggs from 281 to 87 and the level of the hepatoesplenic form cases from 5.9 to 0.0%. In 1991, three years after the interruption of the program, the prevalence had risen to 19.6%. The district consists of Barbosa (a rural area) and Peri-Peri itself (an urban area). In 1991, the prevalence in the two areas was 28.4% and 16.0% respectively. A multivariate analysis of risk factors for schistosomiasis indicated the domestic agricultural activity with population attributive risk (PAR) of 29.82%, the distance (< 10 m) from home to water source (PAR = 25.93%) and weekly fishing (PAR = 17.21%) as being responsible for infections in the rural area. The recommended control measures for this area are non-manual irrigation and removal of homes to more than ten meters from irrigation ditches. In the urban area, it was observed that swimming at weekly intervals (PAR = 20.71%), daily domestic agricultural activity (PAR = 4.07%) and the absence of drinking water in the home (PAR=4.29%) were responsible for infections. Thus, in the urban area the recommended control measures are the substitution of manual irrigation with an irrigation method that avoids contact with water, the creation of leisure options of the population and the provision of a domestic water supply. The authors call attention to the need for the efficacy of multivariate analysis of risk factors to be evaluated for schistosomiasis prior to its large scale use as a indicator of the control measures to be implemented.
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Trabalho de Projeto
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In this work, we associate a p-periodic nonautonomous graph to each p-periodic nonautonomous Lorenz system with finite critical orbits. We develop Perron-Frobenius theory for nonautonomous graphs and use it to calculate their entropy. Finally, we prove that the topological entropy of a p-periodic nonautonomous Lorenz system is equal to the entropy of its associated nonautonomous graph.
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RESUMO - No contexto económico actual, os custos pelos acidentes devem ser tidos em conta por todos os gestores das organizações, com especial destaque ao sector da saúde. Assim a análise económica deste estudo visa alertar para o impacto económico dos acidentes de trabalho em contexto hospitalar e sensibilizar os gestores para a análise do custo-beneficio da prevenção. Existem custos facilmente constatáveis, tais como, o tempo perdido no dia do acidente, quer pelo sinistrado quer pelos colegas de trabalho que o assistem, as despesas de uma ida ao serviço de urgência, a paragem da produção, a formação de mão-de-obra alternativa, a substituição dos trabalhadores, o pagamento de horas extras, o restabelecimento dos trabalhadores, os salários pagos aos trabalhadores sinistrados, as despesas administrativas e o aumento do prémio do seguro, entre outros. Existem outros custos que não são tão evidentes e por conseguinte, dificilmente quantificáveis, como é o caso da deterioração da imagem da empresa e o impacto sentimental que estes provocam nos colegas de trabalho que se traduz em quebras de produtividade. A análise económica foi realizada tendo em conta a definição de várias variáveis, de várias rubricas de custos pertencentes ao mesmo domínio. Neste projecto pretende-se analisar o custo global da sinistralidade segundo três ópticas distintas. A óptica da variabilidade, da imputabilidade e da responsabilidade, de forma a ser possível obter o custo marginal devido à ocorrência de um novo acidente, o montante de custos assumidos pelas empresas e os custos unitários segundo a natureza e a localização da lesão. ---------- ABSTRACT - In the current economic context, the costs originated by labour accidents must be taken in account by all the managers of the organisations, in this case, especially by the health sector. Thus, the economic analysis of this study case aims, to alert for the economic impact of the industrial accidents and motivate the managers for the analysis of the cost-benefit for prevention. There are kinds of costs easily quantified such as, the lost time in the day of the accident, expenses in the urgencies service, production interruption, workforce formation, workers’ substitution, extra work payment, employers’ healing, wages paid to injured workers’, administrative expenses and a biggest insurers’’ prime, among other things. The economic analysis of the labour injuries, was developed taking in account the definition of some variables, of some cost categories which belong to same domain. In this project we pretend to analyse the global cost labour injuries according to three distinct optics: variability, imputability and responsibility. Thus, it became possible to get the cost due to an occurrence of a new accident, the unitary sum of costs assumed by the companies and costs according to nature and the localisation of the injury.
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A racionalização do consumo de energia elétrica é um tema que assume uma importância crescente nos dias de hoje. O elevado consumo de energia, principalmente a nível comercial/industrial, tem motivado o aparecimento de questões políticas, económico-sociais e ambientais que visam a sensibilização dos consumidores para a gestão eficiente dos seus recursos. Neste sentido, as empresas e instituições têm demonstrado interesse em encontrar soluções de gestão nas suas instalações elétricas que permitam a monitorização de indicadores e a previsão de falhas cuja ocorrência acarreta elevados custos de reparação/substituição, de paragem de produção, entre outros. O estudo aqui apresentado surge no âmbito de um projeto académico, cuja finalidade se prende com a implementação de um sistema de monitorização da qualidade e consumo de energia elétrica no Instituto Superior de Engenharia do Porto (ISEP). Baseado numa rede de dispositivos analisadores de parâmetros de energia elétrica, estes equipamentos de medição dispõem de software próprio, o GridVis, que permite o acesso remoto, através de uma rede Ethernet, aos parâmetros de energia (grandezas físicas elétricas). O sistema desenvolvido é capaz de identificar parâmetros de consumo de energia anómalos e emitir alertas, pré-programados em linguagem C++ e diagrama de blocos. Permite, por exemplo, detetar um consumo instantâneo excessivo de energia e alertar a sua ocorrência. As páginas de acesso aos parâmetros medidos por cada dispositivo são acessíveis através de uma interface gráfica desenvolvida em Adobe Flash que inclui, de uma forma simples e organizada, a informação relativa à distribuição dos dispositivos de medição. Num contexto de expansão deste projeto para outros edifícios do ISEP, a solução desenvolvida encontra-se preparada para ser adaptada em qualquer local, desde que reúna certos requisitos.
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Dissertation presented at the Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa to obtain the Master degree in Electrical and Computer Engineering.
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Proteins secreted to the extracellular environment or to the periphery of the cell envelope, the secretome, play essential roles in foraging, antagonistic and mutualistic interactions. We hypothesize that arms races, genetic conflicts and varying selective pressures should lead to the rapid change of sequences and gene repertoires of the secretome. The analysis of 42 bacterial pan-genomes shows that secreted, and especially extracellular proteins, are predominantly encoded in the accessory genome, i.e. among genes not ubiquitous within the clade. Genes encoding outer membrane proteins might engage more frequently in intra-chromosomal gene conversion because they are more often in multi-genic families. The gene sequences encoding the secretome evolve faster than the rest of the genome and in particular at non-synonymous positions. Cell wall proteins in Firmicutes evolve particularly fast when compared with outer membrane proteins of Proteobacteria. Virulence factors are over-represented in the secretome, notably in outer membrane proteins, but cell localization explains more of the variance in substitution rates and gene repertoires than sequence homology to known virulence factors. Accordingly, the repertoires and sequences of the genes encoding the secretome change fast in the clades of obligatory and facultative pathogens and also in the clades of mutualists and free-living bacteria. Our study shows that cell localization shapes genome evolution. In agreement with our hypothesis, the repertoires and the sequences of genes encoding secreted proteins evolve fast. The particularly rapid change of extracellular proteins suggests that these public goods are key players in bacterial adaptation.
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A rede viária de um país proporciona, não só o encurtamento de distâncias como também o desenvolvimento social e económico. Assim, importa que em qualquer ponto do traçado o utilizador possa reconhecer, de forma inequívoca, o seu posicionamento em relação à via e ao seu destino. Neste propósito a sinalização assume um papel fundamental. Sinalização define-se como o interface entre a estrada e o condutor, tendo por base um sistema de comunicação, constituído por mensagens escritas ou simbólicas, que fornecem ao condutor uma correta perceção da estrada em que circula. Este facto, contribui para uma melhoria das condições de segurança rodoviária diminuindo a sua sinistralidade. A nível nacional a sinalização de orientação é regulada pela norma de sinalização vertical de orientação. Todavia identificou-se a necessidade de atualização desta, estando para isso eminente a publicação da versão definitiva da disposição normativa. De referir que ambas não possuem carácter obrigatório, mas constituem um manual de boas práticas na área. Com esta dissertação pretende-se conhecer, a viabilidade e as implicações inerentes à aplicação da disposição normativa, com especial enfoque na metodologia utilizada para a escolha dos destinos inscritos nos painéis de sinalização. Para isso procedeu-se a uma análise comparativa entre a norma de sinalização vertical de orientação e a disposição normativa, através do estudo de casos práticos. Nesse sentido, comparou-se os resultados teóricos obtidos pela aplicação das duas normas e o que, na realidade, se encontra no local. Associadamente procedeu-se a um estudo das normas aplicadas em países europeus de referencia com o intuito de verificar quais as práticas seguidas. Conclui-se, com esta dissertação, que a disposição normativa, pretensa atualização da norma em vigor, carece de diversas melhorias, de forma a proporcionar uma melhor adequação ao panorama rodoviário nacional e proporcionar a continuidade de sinalização orientação transfronteiriça.
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Biosensors have opened new horizons in biomedical analysis, by ensuring increased assay speed and flexibility, and allowing point-of-care applications, multi-target analyses, automation and reduced costs of testing. This has been a result of many studies merging nanotechnology with biochemistry over the years, thereby enabling the creation of more suitable environments to biological receptors and their substitution by synthetic analogue materials. Sol-gel chemistry, among other materials, is deeply involved in this process. Sol-gel processing allows the immobilization of organic molecules, biomacromolecules and cells maintaining their properties and activities, permitting their integration into different transduction devices, of electrochemical or optical nature, for single or multiple analyses. Sol-gel also allows to the production of synthetic materials mimicking the activity of natural receptors, while bringing advantages, mostly in terms of cost and stability. Moreover, the biocompatibility of sol-gel materials structures of biological nature allowed the use of these materials in emerging in vivo applications. In this chapter, biosensors for biomedical applications based on sol-gel derived composites are presented, compared and described, along with current emerging applications in vivo, concerning drug delivery or biomaterials. Sol-gel materials are shown as a promising tool for current, emerging and future medical applications. - See more at: http://www.eurekaselect.com/127191/article#sthash.iPqqyhox.dpuf
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Dissertação para obtenção do Grau de Doutor em Biologia
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Since October 2001, the Adolfo Lutz Institute has been receiving vesicular fluids and scab specimens of patients from Paraíba Valley region in the São Paulo and Minas Gerais States and from São Patricio Valley, in the Goiás State. Epidemiological data suggested that the outbreaks were caused by Cowpox virus or Vaccinia virus. Most of the patients are dairy milkers that had vesiculo-pustular lesions on the hands, arms, forearms, and some of them, on the face. Virus particles with orthopoxvirus morphology were detected by direct electron microscopy (DEM) in samples of 49 (66.21%) patients of a total of 74 analyzed. Viruses were isolated in Vero cell culture and on chorioallantoic membrane (CAM) of embryonated chicken eggs. Among 21 samples submitted to PCR using primers for hemagglutinin (HA) gene, 19 were positive. Restriction digestion with TaqI resulted in four characteristic Vaccinia virus fragments. HA nucleotide sequences showed 99.9% similarity with Cantagalo virus, described as a strain of Vaccinia virus. The only difference observed was the substitution of one nucleotide in the position 616 leading to change in one amino acid of the protein in the position 206. The phylogenetic analysis showed that the isolates clustered together with Cantagalo virus, other Vaccinia strains and Rabbitpox virus.