Kirjallisuutta

Pääosa virallisen vastaväittäjän Guy S. Goodwin-Gillin Lapin yliopiston oikeustieteiden tiedekunnalle antamasta 8.12.1997 päivätystä lausunnosta

Increased renal responsiveness to vasopressin and enhanced V2 receptor signaling in RGS2-/- mice.

The antidiuretic effect of vasopressin is mediated by V2 receptors (V2R) that are located in kidney connecting tubules and collecting ducts. This study provides evidence that V2R signaling is negatively regulated by regulator of G protein signaling 2 (RGS2), a member of the family of RGS proteins. This study demonstrates that (1) RGS2 expression in the kidney is restricted to the vasopressin-sensitive part of the nephron (thick ascending limb, connecting tubule, and collecting duct); (2) expression of RGS2 is rapidly upregulated by vasopressin; (3) the vasopressin-dependent accumulation of cAMP, the principal messenger of V2R signaling, is significantly higher in collecting ducts that are microdissected from the RGS2(-/-) mice compared with their wild-type littermates; and (4) analysis of urine output of mice that were exposed to water restriction followed by acute water loading revealed that RGS2(-/-) mice exhibit an increased renal responsiveness to vasopressin. It is proposed that RGS2 is involved in negative feedback regulation of V2R signaling.

[Illustrations de Le Decameron] / Titien, dess. et peint.; Bonenfant, grav. ; Jean Boccace, aut. du texte

Comprend : [Portrait en reg. folio I : portrait de l'auteur, Jean Boccace, dessiné par P. Jude et gravé par Bonenfant d'après une peinture de Titien.] Johannes Boccatius. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. folio I : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. folio xlviii : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. en reg. folio lxxi : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. en reg. folio lxxiiii : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. en reg. folio xcv : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. avant folio cxv : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. folio cxxviii : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. en reg. folio clxvii : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. en reg. folio ccvii: Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601] ; [Fig. folio ccxxxiiii : Jean Boccace rédigeant son livre.] Bocace. [Cote : Res Y2 402/Microfilm R 1601]

The list of the chromosome races of the common shrew (Sorex araneus)

The list of chromosome races of the common shrew (Sorex araneus) was compiled, the vast literature has been scrutinized, and unpublished data have been added. Altogether, 50 chromosome races could be listed. The name and its synonyms, chromosomal constitution, author of the description, type locality, known distribution range, and additional information are reported for individual races. The present list should be considered a working document that will be regularly updated and supplemented.

Parlamentarismens många ansikten

Abstract: Parliamentary government in different forms