953 resultados para Export Ban
Resumo:
Mode of access: Internet.
Resumo:
Mode of access: Internet.
Resumo:
Mode of access: Internet.
Resumo:
Committee Serial No. 89-79. Considers S. 3298, to ban sale of toys and other articles so hazardous as to be unsuitable for play or use, even with labeling under the Federal Hazardous Substances Labeling Act.
Resumo:
Issued Jan. l, 1953- as U.S. Dept. of Agriculture. Agriculture handbook, no. 49, 79, 113, 192, 242, 281, 317, etc.
Resumo:
Title Varies: Quarterly Report under the Second Decontrol Act of 1947; Export Control & Allocation Powers; Export Control
Resumo:
Mode of access: Internet.
Resumo:
Item 1040-A, 1040-B (microfiche).
Resumo:
On double leaves, oriental style, in 115 cases.
Resumo:
Includes index.
Resumo:
Includes bibliographies.
Resumo:
Thesis (Master's)--University of Washington, 2016-06
Resumo:
Thesis (Ph.D.)--University of Washington, 2016-06
Resumo:
Verapamil inhibits tri-iodothyronine (T-3) efflux from several cell types, suggesting the involvement of multidrug resistance-associated (MDR) proteins in T-3 transport. The direct involvement of P-glycoprotein (P-gp) has not, however, been investigated. We compared the transport of I-125-T-3 in MDCKII cells that had been transfected with mdr1 cDNA (MDCKII-MDR) versus wild-type MDCKII cells (MDCKII), and examined the effect of conventional (verapamil and nitrendipine) and specific MDR inhibitors (VX 853 and VX 710) on I-125-T-3 efflux. We confirmed by Western blotting the enhanced expression of P-gp in MDCKII-MDR cells. The calculated rate of I-125-T-3 efflux from MDCKII-MDR cells (around 0.30/min) was increased twofold compared with MDCKII cells (around 0.15/min). Overall, cellular accumulation of I-125-T-3 was reduced by 26% in MDCKII-MDR cells compared with MDCKII cells, probably reflecting enhanced export of T-3 from MDCKII-MDR cells rather than reduced cellular uptake, as P-gp typically exports substances from cells. Verapamil lowered the rate of I-125-T-3 efflux from both MDCKII and MDCKII-MDR cells by 42% and 66% respectively, while nitrendipine reduced I-125-T-3 efflux rate by 36% and 48% respectively, suggesting that both substances inhibited other cellular T-3 transporters in addition to P-gp. The specific MDR inhibitors VX 853 and VX 710 had no effect of I-125-T-3 efflux rate from wild-type MDCKII cells but reduced I-125-T-3 export in MDCKII-MDR cells by 50% and 53% respectively. These results have provided the first direct evidence that P-gp exports thyroid hormone from cells.