Ditregra - An auxiliary program for structural determination of diterpenes

This work describes the creation of heuristics rules based on 13C-NMR spectroscopy that characterize several skeletal types of diterpenes. Using a collection of 2745 spectra we built a database linked to the expert system SISTEMAT. Several programs were applied to the database in order to discover characteristic signals that identify with a good performance, a large diversity of skeletal types. The heuristic approach used was able to differentiate groups of skeletons based firstly on the number of primary, secondary, tertiary and quaternary carbons, and secondly the program searches, for each group, if there are ranges of chemical shifts that identifies specific skeletal type. The program was checked with 100 new structures recently published and was able to identify the correct skeleton in 65 of the studied cases. When the skeleton has several hundreds of compounds, for example, the labdanes, the program employs the concept of subskeletal, and does not classify in the same group labdanes with double bounds at different positions. The chemical shift ranges for each subskeletal types and the structures of all skeletal types are given. The consultation program can be obtained from the authors. © 1997 - IOS Press. All rights reserved.

Sistemas precursores de cristais líquidos mucoadesivos para administração bucal de curcumina no tratamento do câncer bucal

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito do soro de cães portadores de insuficiência renal sobre a apoptose e o metabolismo oxidativo dos polimorfonucleares

In recent years, uremic toxins have been widely investigated as an immunosuppressive factor for nephropathic patients. This study aimed to test the hypothesis that, as it was similarly observed in humans, the rate of apoptosis and superoxide production in polymorphonuclear leukocytes are changed in dogs treated with uremic serum. The superoxide production of polymorphonuclear leukocytes and apoptotic index of 10 healthy dogs incubated with autologous and homologous serum from healthy and uremic dogs was compared. Thus, there was an effect of partial inhibition of oxidative metabolism in uremia without correlation with the acceleration of polymorphonuclear leukocytes apoptosis in dogs.

Avaliação longitudinal de duas técnicas de sinus lift

The implant has high success rates and predictability in this decade. However, bone availability is a factor that may limit the installation technique of dental implants in subsequent rehabilitation of the maxillary arch has been proposed technique’s maxillary sinus lifting when it presents itself pneumatized, for installation of dental implants The aim of this paper is to present two clinical cases using the surgical technique and rehabilitation to the patient with surgery maxillary sinus lifting with the use of a biomaterial alone or in combination with autogenous bone and the prosthetic resolution radiographic and clinical follow-up of three years.

Implantes curtos do tipo cone-Morse: proporção coroa-implante

The purpose of this study was to analyze the biomechanical interactions in bone tissue between short implants and implant-supported crowns with different heights. Two models were made using the programs InVesalius 3.0, Rhinoceros 4.0 and Solidworks 2010. The models were established from a bone block with the short implant (3.75 x 8.5 mm) with geometry Morse taper connection (MT). The height of the crown (cemented) was set at 10.0 mm and 15.00 mm. The models were processed by programs and 10 NEiNastran Femap 10.0. The force applied was 200N (vertical) and 100N (oblique). The results were plotted on maps Voltage Maximum Principal. Statistical analysis was performed using ANOVA. The results showed that the increase in crown height, increased stress concentration in the crown of 15 mm under oblique loading (p <0.001), the oblique loading has significantly expanded the area of stress concentration (p <0.001). Conclusion:the increase of the crown increased the stress concentration, being statistically significant for short implants Morse taper. The mesial and distal region had the highest concentration of stresses under oblique loading. The oblique loading was more harmful when compared with axial loading, being statistically significant.

Influência do aumento do comprimento de implantes dentários

The use of implants of greater length may be more favorable for the predictability of dental implants. This statement is relevant, since the cause of failures in dental implants are more related to biomechanical complications. The aim of this study was to evaluate the influence of increase of the length around the entire body of the implant. Six models were created with the presence of only one hexagonal implant (Master Screw connection, Implant Systems, São Paulo, Brazil) of 3.75 mm x 7.0 mm (Model A), 3.75 mm x 8.5 mm (Model B ), 3.75 mm x 10.0 mm (Model C) 3.75 mm x 11.5 mm (Model D) 3.75 mm x 13.0 mm (Model E) 3.75 mm x 15.0 mm (Model F) using the method of photoelasticity. The results were visualized through a qualitative analysis of stresses (number and intensity photoelastic fringes). The model A showed a pattern of less favorable stress distribution, the oblique loading was the most detrimental to the related structures. Conclusion: The increased length allowed for a better distribution of stresses. The oblique loading was more detrimental when compared to axial loading.

Coupling between respiratory and sympathetic activities as a novel mechanism underpinning neurogenic hypertension

Enhanced sympathetic outflow to the heart and resistance vessels greatly contributes to the onset and maintenance of neurogenic hypertension. There is a consensus that the development of hypertension (clinical and experimental) is associated with an impairment of sympathetic reflex control by arterial baroreceptors. More recently, chronic peripheral chemoreflex activation, as observed in obstructive sleep apnea, has been proposed as another important risk factor for hypertension. In this review, we present and discuss recent experimental evidence showing that changes in the respiratory pattern, elicited by chronic intermittent hypoxia, play a key role in increasing sympathetic activity and arterial pressure in rats. This concept parallels results observed in other models of neurogenic hypertension, such as spontaneously hypertensive rats and rats with angiotensin II–salt-induced hypertension, pointing out alterations in the central coupling of respiratory and sympathetic activities as a novel mechanism underlying the development of neurogenic hypertension.

O conhecimento das funções e a formação dos auxiliares odontológicos atuantes no serviço público de saúde de municipios do noroeste paulista

The aim of this study was to evaluate the knowledge of Hygienists (TSB) and Dental Auxiliaries (ASB) in relation to their roles regulated by Law number 11.889, December 24th, 2008, and formation of them and capacitating received before they had been admitted in public health system. It’s a transversal and descriptive study where the target population were TSB and ASB (N=76) that works in public service from 5 cities of the DRS II-SP. Data collection was performed by semi-structured instrument with opened and closed questions. The answer rate was 90.79% (n=69). The results showed that the majority of professional know part of their duties (56%) Near half of them had formation course (47.8%). In relation to information received during formation courses, 80% stated had received all information necessary to actualization of knowledge, however, 84% stated to feel necessity to actualize their knowledge to develop their works, 58% of professionals said that they don’t receive capacitating after they had been admitted. It was possible to conclude that the majority of professionals know part of their roles, has formation course and the majority don’t receive capacitating when they are admitted in public health system, however, it was observed that a part of them don’t have specific formation yet and don’t know part of their roles according to current legislation

Modulação autonômica, pressão arterial, aptidão funcional e qualidade de vida em mulheres com hipertensão arterial submetidas a um programa de Hatha Yoga

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Pós-graduação em Comunicação Estratégica: uma contribuição multidisciplinar na busca da capacitação organizacional e do compartilhamento de significados entre universidade e mercado

The present study scores postures, approaches and themes to permeadt discussions and the process of construction of Course Specialization of communication at the Faculty of architecture, arts and communication (FAAC) of Universidade Estadual Paulista (UNESP), Bauru, SP, highlighting the difficulties and the paths chosen in search of professional qualification together organizations. Presentation the investigative process, market over demands from the perspective of organizational communication, to try to understand the multidimensional abilities that the course should provide. Finally, it establishes some modules and thematic for the course, intending to reflect the diversity of communicative functions, which are in the highest capacity of human beings, that is to create your reality and interfere in the direction of society.

Jornalismo e meio ambiente: a contribuição dos meios de comunicação e o conceito de sustentabilidade

This article is a reflection about the contribution the social communication media can provide to the public debate about the environmental concerns. The Agenda XXI and several other UN documents call to the need to inform and educate the society. On the other hand, the Communication theories always have in common the imperative of the emitter to be understood by the recipient, in such a way that they can become change agents and not only observers. The first step is, therefore, to study the environmental question, adequately focus the theme and convey clarification. It is not what happened, for instance, with some technical concepts from the area, in particular sustainability, that came about in the 70 s to guide public policies at the service of the life preservation and specially, future and today, utilized even as a parameter of preservation of profit and advantage resulting from exploitation of nature.Key-Words Theory of Communication - Environmental Sustainability MCM

Denudação química e implicações na composição das águas superficiais da Bacia do Rio Jaú (SP)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Intencionalidades detectadas no processo de elaboração e implementação de um projeto de formação inicial de professores de física

This article presents part of a PhD research that investigated what are the limiting factors to be overcome by an initial training program for teachers of physics in order to achieve the identity profile of your proposed course on Pedagogical Project Course (PPC). From the survey of the intended ideal, the actions taken by professors, coordinators and managers seeking its implementation were analyzed. Data were collected from official documents, field notes taken during meetings between professors and interviews with the subjects belonging to the faculty of the course. This is a research in action grounded in Habermas principles. For data analysis, we used analytical devices of discourse analysis, using the French perspective of Pêcheux. The outline presented here seeks to highlight the intentions identified through the analysis of discourses present in the texts, in the speech of different subjects involved and the actions undertaken by them during this process. What one can conclude is that the intentions of the involved professors are permeated of contractions, since in some aspects they intend to give the program teacher's an identity (licenciature) and in other ones they try to maintain the status quo, that means, a teachers program which a bachelor’s profile.

Swarm-based descriptor combination and its application for image classification

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Síntese e citotoxicidade de curcuminoides e híbridos curcumina-cinamaldeído

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)