Isolamento, cultivo, caracterização e criopreservação de células tronco mesenquimais derivadas de membrana amniótica, geléia de Wharton e sangue do cordão umbilical de fetos bovinos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Aspectos socioeconômicos, indicadores de qualidade do leite e pesquisa de linhagens toxigênicas de Staphylococcus em propriedades de agricultura familiar de Botucatu, SP

Pós-graduação em Medicina Veterinária - FMVZ

Limitações humanas do operador de máquinas agrícolas e o ambiente socio-laboral na sojicultura

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Efeito quimiopreventivo e modulador de HLA-G (Human Leukocyte Antigen - G) de Morelloflavona

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação dos efeitos de aloe-emodin em células uroteliais imortalizadas e neoplásicas cultivadas in vitro

Aloe vera (Aloe barbadensis Miller), popularly known in Brazil as babosa, has a long history of use as medicinal plant for different therapeutic purposes. The components of the plant extract are present in various products of human use, mainly for nutritional and cosmetics purposes. However, some studies suggest that this extract might also have carcinogenic activity. The aloe vera extract is a complex mixture of bioactive compounds. The study of isolated compounds may contribute to elucidate contradictory results about the effects related to the consumption of the plant, as well as their mechanisms of action. One of the most important compound from Aloe vera is aloe-emodin, which is a secondary metabolite generated in the intestinal tract. Putative antimicrobial and antitumor effects were previously attributed to aloe-emodin. Although the exposure of urothelial cells to aloe-emodin was already reported in the literature, only one study showed its effects on urothelial cells, suggesting that aloe-emodin inhibits the viability of T24 cancer cells due to apoptosis induction. Since there is no sufficient information about the effects of aloe-emodin on urothelial cells, and low efficiency in the treatment of bladder cancer currently, the present study aims to evaluate the hypothesis that the treatment with aloe-emodin could impact the behavior of other urothelial cell lines in vitro. Therefore, the in vitro IC50 exposure of aloe-emodin to human immortalized neoplastic urothelial cells will be determinated in order to verify possible differences in the behavior of urothelial cells in vitro treated with aloe-emodin in comparison with untreated cells. Furthermore, differences between cell lines will be also evaluated

Estudo da especificidade e toxicidade do inibidor de hipusinação GC7 utilizando o modelo de Saccharomyces cerevisiae

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Monitoramento de cultivos submersos de linhagens de Streptomyces clavuligerus para a quantificação de distribuição de fluxos metabólicos

Pós-graduação em Biotecnologia - IQ

Identidade das Ciências Humanas e métricas de avaliação: qualis periódicos e classificação de livros

This article aims to discuss the evaluation metrics adopted by Capes in the evaluation process of national graduate programs in the field of the Human Sciences, especially with respect to the classifications of scientific journals and books.

Aspectos biológico-celulares da osseointegração baseados nas superfícies de implantes

Osseointegration involves a cascade of biological events, which can be accelerated by modifying the micro and/or nanometric topography of dental implant surfaces. Considering that different treatment types modify the titanium surface giving it a more pronounced rough topography, and physicochemical changes that appear to positively influence the osseointegration process, a literature review was made on the main types of surface treatments and their influence on the biological and cellular aspects of osseointegration, with publications dating from 1969 until the present moment. Although the precise role of the implant surface on the osseointegration of dental implants is not completely clear, the specific effects of implant surface on bone regeneration, initial kinetics, and evolution of mechanical properties have shown to be quite promising. Thus, based on dental implant surface modifications, osseointegration can be defined as a process by which rigid asymptomatic fixation of an alloplastic material can be achieved and kept in close contact with bone tissue, being resistant to early and late functional loads. This process can be modulated by an appropriate treatment of the alloplastic material surface.

Derivação de células tronco de tecido ovariano na espécie canina

Pós-graduação em Medicina Veterinária - FCAV

O dever moral e o valor das ações humanas segundo Kant

The study aims at approaching the duty concept (Sollen) within Kant´s moral philosophy. Taking into account the notion of moral duty as one of the central concepts in (and to) Kant's practical thought, and in an attempt to offer an elucidation of Kant’s quest (and development) by the supreme principle of moral – the fundaments of the moral value´s detaining action, we will investigate: i) what characterizes one action for duty, in Kant’s moral thought and, ii) why exactly, according to Kant, just the action, precisely for duty, is the only action with the genuine value, namely, the moral value.

Amizade e a virtualização das relações humanas na sociedade contemporânea: reflexões a partir de Zygmunt Bauman

This article analyzes the human bonds in the context of contemporary society from the work of the polish sociologist Zygmunt Bauman. Taking as starting point the bond of friendship and relational virtualization process motivated by the development of new technologies, it was observed the occurrence in the present world an affective-relational impoverishment. As an alternative to this, it is argued the exercise of building and maintenance of dense bonds that provide an alternative to the bind model of momentary satisfaction, this time marks. Finally, it is indicated that the discussion of friendship necessarily imply on the problematization of contemporary ethics which will provide the foundation for building a new affective political.

Interações metodológicas e interrelações humanas: alicerçando a transdisciplinaridade no campo da saúde no trabalho

This article provides reflections and discussions about the importance of human interactions and methodological interrelations to substantiate the integrity in the transdisciplinary process in teams that operate in health area. Should be taken as reference the Complexity Theory of Edgar Morin, the logic transdisciplinary of Basarab Nicolescu and the formation groups principles based on the Socionomic Theory of Jacob Levy Moreno. It was concluded that the complexity of the methodologies in the field of workplace health, are influenced by factors that intersect between the scientific interaction and human interrelationships, which allow the transdisciplinary construction. However, the constructions requires the development of professionals in their areas and in their relationship with others as a way of supporting the perspective of transdisciplinarity, ie, interaction, in which different individuals are interrelated with the methodologies and providing articulations and coconstructions from which actualize the transformations.

Variabilidade do padrão de esterases e atividade da glutationa S-transferase em linhagens geográficas de Drosophila melanogaster e D. simulans resistentes e suscetíveis ao inseticida DDT

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)