Human Tissue Kallikrein Activity in Angiographically Documented Chronic Stable Coronary Artery Disease

AbstractBackground:Human tissue kallikrein (hK1) is a key enzyme in the kallikrein–kinin system (KKS). hK1-specific amidase activity is reduced in urine samples from hypertensive and heart failure (HF) patients. The pathophysiologic role of hK1 in coronary artery disease (CAD) remains unclear.Objective:To evaluate hK1-specific amidase activity in the urine of CAD patientsMethods:Sixty-five individuals (18–75 years) who underwent cardiac catheterism (CATH) were included. Random midstream urine samples were collected immediately before CATH. Patients were classified in two groups according to the presence of coronary lesions: CAD (43 patients) and non-CAD (22 patients). hK1 amidase activity was estimated using the chromogenic substrate D-Val-Leu-Arg-Nan. Creatinine was determined using Jaffé’s method. Urinary hK1-specific amidase activity was expressed as µM/(min · mg creatinine) to correct for differences in urine flow rates.Results:Urinary hK1-specific amidase activity levels were similar between CAD [0.146 µM/(min ·mg creatinine)] and non-CAD [0.189 µM/(min . mg creatinine)] patients (p = 0.803) and remained similar to values previously reported for hypertensive patients [0.210 µM/(min . mg creatinine)] and HF patients [0.104 µM/(min . mg creatinine)]. CAD severity and hypertension were not observed to significantly affect urinary hK1-specific amidase activity.Conclusion:CAD patients had low levels of urinary hK1-specific amidase activity, suggesting that renal KKS activity may be reduced in patients with this disease.

Plantae Yucatanae. (Regionis Antillanae) Plants of the insular, coastal and plain regions of the peninsula of Yucatan, Mexico. [By Charles Frederick Millspaugh.].

v.3:no.1(1903)

Flora of the Aguan valley and the coastal regions near La Ceiba, Honduras, by T. G. Yuncker.

v.9:no.4(1940)

Systematics of Laccaria (Agaricales) in the continental United States and Canada, with discussions on extralimital taxa and descriptions of extant types / Gregory M. Mueller.

n.s. no.30(1992)

Taxonomia e distribuição de Actinocythereis brasiliensis sp. nov. (Podocopida, Trachyleberididae) na plataforma continental brasileira

A new species is described, Actinocythereis brasiliensis, from the southern Brazilian continental shelf. It is based on the analysis of 766 samples collected by oceanographical projects. The geographical distribution of this species has revealed its preference by the cold waters and terrigenous sediments and, has a bathymetric distribution between 22 and 164 m but, being concentrated in the shallower waters (< 60 m).

Tadpoles of the forested regions of Borneo / Robert F. Inger.

n.s. no.26(1985)

Distribuição das espécies de corais azooxantelados na plataforma e talude continental superior do sul do Brasil

Dentre os organismos registrados para águas profundas (> 100 m) no sul do Brasil, podemos destacar os corais azooxantelados pertencentes a ordem Scleractinia. Através de análises estatísticas, identificação de espécimes depositados em coleções científicas, e compilação de todos os registros pretéritos destes cnidarios ocorrentes no sul e parte do sudeste do Brasil, foi possível constatar que as coordenadas abrangidas no presente estudo representam uma área de transição entre os corais azooxantelados ocorrentes ao norte e as espécies mais características das zonas polares, principalmente em relação às espécies solitárias. Com a análise da distribuição batimétrica, foi observado um significativo aumento no número de espécies entre o setor de plataforma externa e 500 m de profundidade. Finalizando, foi realizada a análise de agrupamento, o que permitiu discriminar a formação de 6 biótopos das associações de corais azooxantelados para a área de estudo. Desta forma, apresentamos a primeira tentativa de se compreender a distribuição desta pouco conhecida fauna da plataforma e talude continental superior, entre 24ºS e 34ºS.

Use of tobacco in New Guinea and neighboring regions / by Albert B. Lewis, Assistant Curator of Melanesian Ethnology.

no.17(1924)

Dosilia (Porifera, Demospongiae) redefined

Dosilia plumosa (Carter, 1849), type species of the genus, and D. brouni (Kirkpatrick, 1906), with distribution respectively in the Oriental and Ethiopic regions, are revised based on a SEM analysis of spicules, gemmules and skeletal structure. The lectotype here designated for D. plumosa is illustrated as well as the holotype by monotypy determined for D. brouni. Dosilia palmeri (Potts, 1885) and D. radiospiculata (Mills, 1888) distributed in the Nearctic and Neotropical regions and D. pydanieli Volkmer-Ribeiro, 1992, found in the Neotropical region, are revised based on a SEM analysis of spicules, gemules and skeletal structure. The holotype by monotypy is determined for D. radiospiculata. Heteromeyenia plumosa Weltner,1895 is synonymyzed with D. radiospiculata. Upon the revision of its five species, the genus is redefined and a key presented.

Distribuição geográfica da fauna e flora da Baía de Guanabara

The author studied, the horizontal and vertical distribution of most common part of the flora and fauna of the bay of Guanabara at Rio de Janeiro. In this paper the eulittoral, poly, meso and oligohaline regions were localised and studied; and the first chart of its distribution was presented (fig. 2). The salinity of superficial waters was established through determinations based on 30 trips inside the buy for collecting biological materials. Some often 409 determinations which were previous reported together with the present ones served for the eleboration of a salinity map of the bay of Guanabara (fig. 1). This map of fig. 2 shows the geographic locations of the water regions. EULITTORAL WATER REGIME — Fig. 3 shows the diagram scheme of fauna and flora of this regime. Sea water salinity 34/1.000, density mean 1.027, transparent greenish waters, sea coast with moderate bursting waves. Limpid sea shore with white sand, gneiss with the big barnacle Tetraclita squamosa var. stalactifera (Lam. Pilsbry. Vertical distributions: barna¬cles layers with a green region in which are present the oyster Ostrea pa-rasitica L., the barnacles Tetraclita, Chthamalus, Balanus tintinnabulum var. tintinnabulum (L.) e var. antillensis Pilsbry in connection with several mollusca and the sea beatle Isopoda Lygia sp. Covered by water and exposed to air by the tidal ritms, there is a stratum of brown animals that is the layer of mussels Mytilus perna L., with others brown and chestnut animals : the Crustacea Pachygrapsus, the little crab Porcellana sp., the stone crab Me-nippe nodifrons Stimpson, the sea stars Echinaster brasiliensis (Mull. & Tr.), Astropecten sp. and the sea anemones Actinia sp. Underneath and never visible there is a subtidal region with green tubular algae of genus Codium and amidst its bunches the sea urchin Lycthchinus variegatus (Agass.) walks and more deeply there are numerous sand-dollars Encope emarginata (Leske). The microplancton of this regime is Ceratiumplancton. POLYHALINE WATER REGIMB — Water almost sea water, but directly influenced by continental lands, with rock salts dissolved and in suspension. Salinity: 33 to 32/1.000. This waters endure the actions of the popular nicknamed «water of the hill» (as the waters of mesohaline and oligohaline regimes), becoming suddenly reddish during several hours. That pheno¬menon returns several times in the year and come with great mortality of fishes. In these waters, according to Dr. J. G. FARIA there are species of Protozoa : Peridinea, the Glenoidinium trochoideum St., followed by its satellites which he thinks that they are able to secret toxical substances which can slaughter some species of fishes. In these «waters of the hill» was found a species of Copepoda the Charlesia darwini. In August 1946 the west shore of the Guanabara was plenty of killed fishes occupying a area of 8 feet large by 3 nautical miles of lenght. The enclosure for catching fishes in the rivers mouthes presents in these periods mass dead fishes. The phenomenon of «waters of the hill» appears with the first rains after a period of long dryness. MESOHALINE WATER REGIME — Fig. 4 shows the the diagramm scheme. Salt or brackish water from 30 to 17/1.000 salinity, sometimes until 10/1.000. Turbid waters with mud in suspension, chestnut, claveyous waters; shore dirty black mud without waving bursting; the waters are warmer and shorner than those of the polihaline regime. Mangrove shore with the mangrove trees : Rhizophora mangle L., Avicennia sp., Laguncularia sp., and the »cotton tree of sea» Hibiscus sp. Fauna: the great land crab «guaimú» Cardisoma guanhumi Latr., ashore in dry firm land. There is the real land crab Ucides cordatus (L.) in wetting mud and in neigh¬ bourhood of the burrows of the fiddler-crabs of genus Uca. On stones and in the roots of the Rhizophora inhabits the brightly colored mangrove-tree-crab («aratu» Portuguese nickname) Goniopsis cruentata (Latreille) and the sparingly the big oyster Ostrea rhizophorae Guild. Lower is the region of barnacles Balanus amphitrite var. communis Darwin and var. niveus Darwin; Balanus tintinnabulum var. tintinnabulum (L.) doesn't grow in this brackish water; lower is the region of Pelecipoda with prepollency of Venus and Cytherea shell-fishes and the Panopeus mud crab; there are the sea lettuce Ulva and the Gastreropod Cerithium. The Paguridae Clibanarius which lives in the empty shells of Gasteropod molluscs, and the sessile ascidians Tethium plicatum (Lesuer) appears in some seasons. In the bottom there is a black argillous mud where the «one landed shrimps» Alpheus sp. is hidden. OLIGOHALINE WATER REGIME — The salinity is lower than 10/1.000. average 8/1.000. There are no barnacles and no sea-beetles Isopods of genus Lygia; on the hay of the shore there are several graminea. This brackish water pervades by mouthes of rivers and penetrates until about 3 kilometers river above. While there is some salt dissolved in water, there are some mud crabs of the genus Uca, Sesarma, Metasesarma and Chasmagnatus. The presence of floating green plants coming from the rivers in the waters of a region indicated the oligohaline waters, with low salt content because when the average of NaCl increases above 8/1.000 these plants die and become rusty colored.