Computer-modeling origin of a simple genetic apparatus

This computer simulation is based on a model of the origin of life proposed by H. Kuhn and J. Waser, where the evolution of short molecular strands is assumed to take place in a distinct spatiotemporal structured environment. In their model, the prebiotic situation is strongly simplified to grasp essential features of the evolution of the genetic apparatus without attempts to trace the historic path. With the tool of computer implementation confining to principle aspects and focused on critical features of the model, a deeper understanding of the model's premises is achieved. Each generation consists of three steps: (i) construction of devices (entities exposed to selection) presently available; (ii) selection; and (iii) multiplication of the isolated strands (R oligomers) by complementary copying with occasional variation by copying mismatch. In the beginning, the devices are single strands with random sequences; later, increasingly complex aggregates of strands form devices such as a hairpin-assembler device which develop in favorable cases. A monomers interlink by binding to the hairpin-assembler device, and a translation machinery, called the hairpin-assembler-enzyme device, emerges, which translates the sequence of R1 and R2 monomers in the assembler strand to the sequence of A1 and A2 monomers in the A oligomer, working as an enzyme.

On the verge of crisis? Mounting economic problems in Belarus. OSW Commentary No. 51, 2011-04-06

Belarus’s financial condition has visibly worsened since the beginning of this year. The severe falls in the country’s foreign currency reserves and its shortage of foreign currency on the international market pose an increasing threat to the stability of the Belarusian economy. Fearing an outbreak of public dissatisfaction, The government has so far been trying to avoid devaluing the rouble or structural economic reforms. Maintaining full control inside the country and the stability of the authoritarian regime are still the main concerns for President Alyaksandr Lukashenka. For this reason, the actions taken by the Belarusian government have been limited to imposing short-term administrative restrictions on the foreign currency market and obtaining external support in the form of loans. Given Belarus’s falling creditworthiness, Minsk is only able to ask Russia for financial support, thus offering the Kremlin more opportunities to realise its desire to take over strategic industrial plants in Belarus. However, the present economic problems of Belarus are so serious that no loan will be able to safeguard its government from the need of carrying out serious economic reforms.

On the ordering, enumeration and ranking of k-ary trees /

"UILU-ENG 77 1706."

Simulation analysis of a network computer,

Bibliography: p. 43.

Further negative results regarding the use of continued fractions for digital computer arithmetic /

Mode of access: Internet.

Initial value problems : practical theoretical developments /

"UILU-ENG 79-1708."

The statistical estimation of throughput and turnaround functions for a university computer system /

Vita.

Communication net of modular processors for a multiprocessor computer /

"This work was submitted in partial fulfillment of the requirements for the degree of Master of Science in Electrical Engineering, June 1967, and was supported in part by the AEC under Contract No. USAEC AT(11-1)1018.

On a negative result regarding the use of continued fractions for digital computer arithmetic /

Includes bibliographical references.

Parallel algorithms for network routing problems and recurrences /

"Grant no. US NSF MCS75-21758."

Prepaging and applications to structured array problems /

Vita.

Computer methods for analysis and synthesis of visual texture,

"C00-2118-0048."

RASCEL: a programmable analog computer based on a regular array of stochastic computing element logic

Thesis--University of Illinois.

The status of investigations into the use of continued fractions for computer hardware /

Bibliography: p. 29.

A class of algorithms for automatic evaluation of certain elementary functions in a binary computer.

"Supported in part...under Grant No. US NSF GJ812 and Grant No. US NSF GJ813."