The peruvian upwelling ecosystem: dynamics and interactions

446 p.

Implementació d'un gestor de contrasenyes online

Aquest TFC proposa la implementació d'un gestor de contrasenyes online que ha de garantir unes funcionalitats mínimes de desar i recuperar contrasenyes alhora que ha de garantir la confidencialitat de les dades emmagatzemades al servidor.

Análisis de la comunicación online de las marcas de moda de España: estudio de caso Mango

Amb la revolució digital van apareixe noves eines informàtiques i plataformes q donen lloc a les jnteraccions en línea, com les xarxes socials i Blogs, aquestes han canviat la manera de comunicació entre les marques i les seves audiències. L' indústria de la moda no ha estat inmune a aquestes transformacions i ha estat adaptar-se al nou format. La recerca presenta una estructura deductiva: Moda Marca Moda- Marques de Moda Espanyola i altres exemples-cas moda- estudio maneta de comunicació online i offline. En aquest últim apartat mostra els resultats de l'anàlisi de les accions comunicatives quotidianes de Marca de Moda Mango, en un període determinat de temps. L'estudi conclou q les accions online i offline és completamenten, es relacionen entre si, evolucionen i donen lloc a una nova forma de comunicació

Redes digitales de comunicación, participación ciudadana y periodismo online durante la primavera árabe: Túnez, 17 de diciembre de 2010-23 de octubre de 2011.

El presente proyecto de investigación se presenta como trabajo final del Máster en Estudis Avançats en Comunicació Social y pretende sentar las bases de la futura tesis doctoral. Se plantea una investigación que tiene como objetivo determinar la capacidad que tuvo el uso de las redes digitales de comunicación para modificar la esfera pública durante la primavera árabe en Túnez y el posterior proceso de Transición llevado a cabo. Para ello la investigación se aborda desde tres conceptos clave: el pluralismo mediático, la relevancia mediàtica y los procesos comunicativos. La investigación se abordará triangulando los métodos cuantitativo y cualitativo y se propone como técnica el anàlisis de contenido sobre la nueva legislación tunecina en materia de Políticas de Comunicación, así como del contenido generado por los usuarios en las redes digitales de comunicación y las noticias de medios de referencia online árabes (3) y occidentales (4) en relación con el objeto de estudio.

Publicidade na Internet Análise comparativa da Publicidade nos sites de três Jornais Online em Cabo Verde

O presente trabalho de Memória intitulado “Publicidade na Internet: Análise comparativa da publicidade nos sites de três jornais online em Cabo Verde”, realiza-se no âmbito da de licenciatura em Ciências da Comunicação variante publicidade na Universidade conclusão Jean Piaget de Cabo Verde. m meio importante publicidade. Pretende-se determinar que recursos da Internet estão a ser Objectiva-se com este trabalho, compreender até que ponto a Internet é u para a veiculação de aproveitados e aplicados pelos anunciantes em Cabo Verde para fazerem as suas online e que tipos serviços os jornais oferecem aos seus clientes ou anunciantes. A anális será feita tendo como base os parâmetros como os tipos de publicidade online, as suas form de comércio e os tipos de interactividade oferecida. Será efectuada uma an publicidade online feita actualmente em Cabo Verde, confrontando com como meio publicitário e com alguns estudos desenvolvidos anteriorment em Cabo Verde. divulgações e as álise crítica sobre a o potencial da web e sobre este assunto

DietPlan : Desenvolupament d’un assistent nutricional online

Avui en dia, Internet permet ampliar l'horitzó d'alguns serveis, donant-los un altre caire més versàtil i còmode pel client final. El fet de posar a disposició del client un servei com el de la dietètica i la nutrició 24 hores al dia i 7 dies a la setmana, sense que perdi el seu valor i continui sent individualitzat, ofereix al client un coaching en aquest terreny i, al negoci, una altra visió del mateix. Així doncs, el principal objectiu és desenvolupar un lloc web, on l'usuari final pugui rebre una valoració dietètica i nutricional del seu estat actual de manera automàtica i, a la vegada, se li aportin els punts on pot millorar i una dieta escaient. Tot i així, la figura del professional en dietètica participarà del procés, ja que sempre existiran casos més complicats que d'altres.

Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptor

In Duchenne muscular dystrophy (DMD), a persistently altered and reorganizing extracellular matrix (ECM) within inflamed muscle promotes damage and dysfunction. However, the molecular determinants of the ECM that mediate inflammatory changes and faulty tissue reorganization remain poorly defined. Here, we show that fibrin deposition is a conspicuous consequence of muscle-vascular damage in dystrophic muscles of DMD patients and mdx mice and that elimination of fibrin(ogen) attenuated dystrophy progression in mdx mice. These benefits appear to be tied to: (i) a decrease in leukocyte integrin α(M)β(2)-mediated proinflammatory programs, thereby attenuating counterproductive inflammation and muscle degeneration; and (ii) a release of satellite cells from persistent inhibitory signals, thereby promoting regeneration. Remarkably, Fib-gamma(390-396A) (Fibγ(390-396A)) mice expressing a mutant form of fibrinogen with normal clotting function, but lacking the α(M)β(2) binding motif, ameliorated dystrophic pathology. Delivery of a fibrinogen/α(M)β(2) blocking peptide was similarly beneficial. Conversely, intramuscular fibrinogen delivery sufficed to induce inflammation and degeneration in fibrinogen-null mice. Thus, local fibrin(ogen) deposition drives dystrophic muscle inflammation and dysfunction, and disruption of fibrin(ogen)-α(M)β(2) interactions may provide a novel strategy for DMD treatment.

Publicidade na Internet Análise comparativa da Publicidade nos sites de três Jornais Online em Cabo Verde

Sumário O presente trabalho de Memória intitulado “Publicidade na Internet: Análise comparativa da publicidade nos sites de três jornais online em Cabo Verde”, realiza-se no âmbito da conclusao de licenciatura em Ciências da Comunicação variante publicidade na Universidade conclusão Jean Piaget de Cabo Verde. m meio importante publicidade. Pretende-se determinar que recursos da Internet estão a ser Objectiva-se com este trabalho, compreender até que ponto a Internet é u para a veiculação de aproveitados e aplicados pelos anunciantes em Cabo Verde para fazerem as suas online e que tipos serviços os jornais oferecem aos seus clientes ou anunciantes. A anális será feita tendo como base os parâmetros como os tipos de publicidade online, as suas form de comércio e os tipos de interactividade oferecida. Será efectuada uma an publicidade online feita actualmente em Cabo Verde, confrontando com como meio publicitário e com alguns estudos desenvolvidos anteriorment em Cabo Verde. divulgações e as álise crítica sobre a o potencial da web e sobre este assunto em Cabo Verde.

Botiga online

Botiga virtual en format web, feta amb arquitectura J2EE i treballada amb Struts2. S'ha utilitzat el PostgreSQL per tractar les dades en taules i HTML pel disseny de les pàgines web.

Interactions médicamenteuses dans le traitement de la douleur

L'association de plusieurs substances est parfois nécessaire pour un traitement efficace de la douleur. L'administration concomitante de plusieurs molécules expose donc, comme lors de tout traitement, au risque d'interactions médicamenteuses. Ces interactions peuvent être souhaitées et recherchées (lorsque l'on vise un effet additif ou une synergie entre plusieurs traitements) ou non désirées, provoquant la survenue d'effets indésirables ou la perte d'efficacité des traitements prescrits . L'importance de ces interactions et leur traduction depend bien sûr des substances concernées mais aussi de la predisposition individuelle de chaque patient, les polymorphisms génétiques dans le metabolism ou le transport de ces médicaments ainsi que lespathologies sous-jacentes y jouant un rôle non négligeable.

Evaluation of an online, case-based interactive approach to teaching pathophysiology

Rapport de synthèse : L'article qui fait l'objet de ma thèse évalue une nouvelle approche pédagogique pour l'apprentissage de certains chapitres de physiopathologie. Le dispositif pédagogique se base sur l'alternance d'apprentissage ex-cathedra et de l'utilisation d'un site web comprenant des vignettes cliniques. Lors de la consultation de ces-dernières, l'étudiant est invité à demander des examens de laboratoire dont il pourrait justifier la pertinence selon le cas clinique étudié. La nouveauté du procédé réside dans le fait que, préalablement à son cours ex-cathedra, l'enseignant peut consulter les statistiques de demandes de laboratoire et ainsi orienter son cours selon les éléments mal compris par les étudiants. A la suite du cours ex-cathedra, les étudiants peuvent consulter sur internet la vignette clinique complète avec des explications. A l'issue de tout le cours, une évaluation auprès des étudiants a été conduite. Le procédé a été mis en place durant deux années consécutives et l'article en discute notamment les résultats. Nous avons pu conclure que cette méthode innovatrice d'enseignement amène les étudiants à mieux se préparer pour les cours ex-cathedra tout en permettant à l'enseignant d'identifier plus précisément quelles thématiques étaient difficiles pour les étudiants et donc d'ajuster au mieux son cours. Mon travail de thèse a consisté à créer ce dispositif d'apprentissage, à créer l'application web des vignettes cliniques et à l'implanter durant deux années consécutives. J'ai ensuite analysé les données des évaluations et écrit l'article que j'ai présenté à la revue 'Medical Teacher'. Après quelques corrections et précisions demandées par le comité de lecture, l'article a été accepté et publié. Ce travail a débouché sur une seconde version de l'application web qui est actuellement utilisée lors du module 3.1 de 3è année à l'Ecole de Médecine à Lausanne. Summary : Since the early days of sexual selection, our understanding of the selective forces acting on males and females during reproduction has increased remarkably. However, despite a long tradition of experimental and theoretical work in this field and relentless effort, numerous questions remain unanswered and many results are conflicting. Moreover, the interface between sexual selection and conservation biology has to date received little attention, despite existing evidence for its importance. In the present thesis, I first used an empirical approach to test various sexual selection hypotheses in a population of whitefish of central Switzerland. This precise population is characterized by a high prevalence of gonadal alterations in males. In particular, I challenged the hypothesis that whitefish males displaying peculiar gonadal features are of lower genetic quality than other seemingly normal males. Additionally, I also worked on identifying important determinant of sperm behavior. During a second theoretical part of my work, which is part of a larger project on the evolution of female mate preferences in harvested fish populations, I developed an individual-based simulation model to estimate how different mate discrimination costs affect the demographical behavior of fish populations and the evolutionary trajectories of female mate preferences. This latter work provided me with some insight on a recently published article addressing the importance of sexual selection for harvesting-induced evolution. I built upon this insight in a short perspective paper. In parallel, I let some methodological questions drive my thoughts, and wrote an essay about possible synergies between the biological, the philosophical and the statistical approach to biological questions.

Interactions between respiration and systemic hemodynamics. Part II: practical implications in critical care.

In Part I of this review, we have covered basic concepts regarding cardiorespiratory interactions. Here, we put this theoretical framework to practical use. We describe mechanisms underlying Kussmaul's sign and pulsus paradoxus. We review the literature on the use of respiratory variations of blood pressure to evaluate volume status. We show the possibilities of attaining the latter aim by investigating with ultrasonography how the geometry of great veins fluctuates with respiration. We provide a Guytonian analysis of the effects of PEEP on cardiac output. We terminate with some remarks on the potential of positive pressure breathing to induce acute cor pulmonale, and on the cardiovascular mechanisms that at times may underly the failure to wean a patient from the ventilator.

Gestión del proyecto para una plataforma online de intercambio, compra o venta de ayudas técnicas

Gestión del proyecto para la creación de una plataforma online de intercambio, compra o venta de ayudas técnicas para personas con discapacidad entre particulares.

NOTCH1 can initiate NF-κB activation via cytosolic interactions with components of the T cell Signalosome.

T cell stimulation requires the input and integration of external signals. Signaling through the T cell receptor (TCR) is known to induce formation of the membrane-tethered CBM complex, comprising CARMA1, BCL10, and MALT1, which is required for TCR-mediated NF-κB activation. TCR signaling has been shown to activate NOTCH proteins, transmembrane receptors also implicated in NF-κB activation. However, the link between TCR-mediated NOTCH signaling and early events leading to induction of NF-κB activity remains unclear. In this report, we demonstrate a novel cytosolic function for NOTCH1 and show that it is essential to CBM complex formation. Using a model of skin allograft rejection, we show in vivo that NOTCH1 acts in the same functional pathway as PKCθ, a T cell-specific kinase important for CBM assembly and classical NF-κB activation. We further demonstrate in vitro NOTCH1 associates physically with PKCθ and CARMA1 in the cytosol. Unexpectedly, when NOTCH1 expression was abrogated using RNAi approaches, interactions between CARMA1, BCL10, and MALT1 were lost. This failure in CBM assembly reduced inhibitor of kappa B alpha phosphorylation and diminished NF-κB-DNA binding. Finally, using a luciferase gene reporter assay, we show the intracellular domain of NOTCH1 can initiate robust NF-κB activity in stimulated T cells, even when NOTCH1 is excluded from the nucleus through modifications that restrict it to the cytoplasm or hold it tethered to the membrane. Collectively, these observations provide evidence that NOTCH1 may facilitate early events during T cell activation by nucleating the CBM complex and initiating NF-κB signaling.

Pathogenic plant-microbe interactions. What we know and how we benefit

Plants, like humans and other animals, also get sick, exhibit disease symptoms, and die. Plant diseases are caused by environmental stress, genetic or physiological disorders and infectious agents including viroids, viruses, bacteria and fungi. Plant pathology originated from the convergence of microbiology, botany and agronomy; its ultimate goal is the control of plant disease. Microbiologists have been attracted to this field of research because of the need for identification of the agents causing infectious diseases in economically important crops. In 1878—only two years after Pasteur and Koch had shown for the first time that anthrax in animals was caused by a bacteria—Burril, in the USA, discovered that the fire blight disease of apple and pear was also caused by a bacterium (nowadays known as Erwinia amylovora). In 1898, Beijerinck concluded that tobacco mosaic was caused by a “contagium vivum fluidum” which he called a virus. In 1971, Diener proved that a potato disease named potato spindle tuber was caused by infectious RNA which he called viroid