Mediação do processo ensino-aprendizagem com o jogo de empresas mercado virtual: uma pesquisa de opinião

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

New approaches by highway agencies in dealing with road users

The context in which society develops has changed. The principles of democracy and human rights, in addition to the explosive development of communications, have encouraged citizens' desire for involvement in many areas which formerly had been the preserve of the State. This is also reflected in the attitudes of public utility customers, who are no longer prepared to accept mediocre service from the bodies responsible; on the contrary, they are increasingly putting pressure on those bodies, demanding better service in return for the charges they pay. Road agencies are no exception. They can no longer maintain their traditional isolation from the public and from users in areas such as decision-making or accountability for results achieved. Furthermore, it is no longer enough to provide road networks; these must be managed in such a way as to ensure improved levels of service, acceptable to users who are more and more demanding. This is why conventional styles of highway management have become unsatisfactory and new approaches are developing. There is a gradual increase in openness to the interests and views of users, who are increasingly considered as partners and participants in management. There are numerous examples in various countries, including those of Latin America, of this significant change; it is likely to cause a major transformation in the way in which public highways are managed. The innovations are recent, many of them still at the embryonic stage. A wide variety of concrete measures have been proposed or tried out. It is not yet possible to predict the size or scope of these changes, or which of them will ultimately become normal practice, but the changes have begun. The purpose of this article is to outline the principal changes which are being observed and the new outlook for road users.

Socio-demographic analysis of youth in the Caribbean- a three country case study

Many Caribbean youth are doing reasonably well. They live in loving and caring families, attend school and are involved in various social activities in their communities. The health and well-being of the children and youth1 in the Caribbean is, and has been, the centre of attention of many studies, meetings and policy directives set at the regional, subregional and national levels. Programmes have been put in place to address the basic needs of young children in the areas of health and education and to provide guidance and directives to youth and adolescents in the area of professional formation and transition to adulthood. Critical issues such as reproductive health and family planning combined with access to education and information on these topics have been promoted to some extent. And finally, the Caribbean is known for rather high school enrolment rates in primary education that hardly show any gender disparities. While the situation is still good for some, growing numbers of children and youth cannot cope anymore with the challenges experienced quite early in their lives. Absent parents, instable care-taking arrangements, violence and aggression subjected to at home, in schools and among their friends, lack of a perspective in schools and the labour-market, early sexual initiation and teenage pregnancies are some of those issues faced by a rising number of young persons in this part of the world. Emotional instability, psychological stress and increased violence are one of the key triggers for increased violence and involvement in crime exhibited by ever younger youth and children. Further, the region is grappling with rising drop-out rates in secondary education, declining quality schooling in the classrooms and increasing numbers of students who leave school without formal certification. Youth unemployment in the formal labour market is high and improving the quality of professional formation along with the provision of adequate employment opportunities would be critical to enable youth to complete consistently and effectively the transition into adulthood and to take advantage of the opportunities to develop and use their human capital in the process. On a rather general note, the region does not suffer from a shortage of policies and programmes to address the very specific needs of children and youth, but the prominent and severe lack of systematic analysis and monitoring of the situation of children, youth and young families in the Caribbean does not allow for targeted and efficient interventions that promise successful outcomes on the long term. In an effort to assist interested governments to fill this analytical gap, various initiatives are underway to enhance data collection and their systematic analysis2. Population and household censuses are conducted every decade and a variety of household surveys, such as surveys of living conditions, labour force surveys and special surveys focusing on particular sub-groups of the population are conducted, dependent on the resources available, to a varying degree in the countries of the region. One such example is the United Nations Children’s Fund (UNICEF)-funded Multi-Indicator Cluster Surveys (MICS) that assess the situation of children and youth in a country. Over the past years and at present, UNICEF has launched a series of surveys in a number of countries in the Caribbean3. But more needs to be done to ensure that the data available is analyzed to provide the empirical background information for evidence-based policy formulation and monitoring of the efficiency and effectiveness of the efforts undertaken.

Análise de associações de polimosfismos HPA, indicadores de autoimunidade e manifestações reumatológicas na Hepatite C

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Análise de parâmetros espermáticos e fertilidade de ratos Wistar expostos ao interferon alfa

Pós-graduação em Biologia Geral e Aplicada - IBB

Undergraduate research in medical education: a descriptive study of students' views

Background: Medical students engage in curricular and extracurricular activities, including undergraduate research (UR). The advantages, difficulties and motivations for medical students pursuing research activities during their studies have rarely been addressed. In Brazil, some medical schools have included undergraduate research into their curriculum. The present study aimed to understand the reality of scientific practice among medical students at a well-established Brazilian medical school, analyzing this context from the students' viewpoint.Methods: A cross-sectional survey based on a questionnaire applied to students from years one to six enrolled in an established Brazilian medical school that currently has no curricular UR program.Results: The questionnaire was answered by 415 students, 47.2% of whom were involved in research activities, with greater participation in UR in the second half of the course. Independent of student involvement in research activities, time constraints were cited as the main obstacle to participation. Among students not involved in UR, 91.1% said they favored its inclusion in the curriculum, since this would facilitate the development of such activity. This approach could signify an approximation between the axes of teaching and research. Among students who had completed at least one UR project, 87.7% said they would recommend the activity to students entering the course.Conclusion: Even without an undergraduate research program, students of this medical school report strong involvement in research activities, but discussion of the difficulties inherent in its practice is important to future developments.

Deregulation of Annexin-A1 and Galectin-1 Expression in Precancerous Gastric Lesions: Intestinal Metaplasia and Gastric Ulcer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Encampment time : an anthropological analysis of the land occupations in Brazil

In this article the social trajectory of a land occupation participant, an encamped woman (Edesmaria) who is a member of an extended landless family, is closely examined in order to demonstrate the inner workings of what is called 'the world of land occupations' in Brazil. Through a native expression (encampment time), it is demonstrated that nowadays, for some individuals, involvement in land occupations and landless workers' movements represents not just an opportunity to claim a parcel of land, but, even more importantly, a chance for social mobility and recognition. In this sense, encampment time is a social code and, as such, it not only quantifies the amount of time spent in a given encampment, but it is also a marker of prestige and status as well as a principle that organises and orders social relations in the land occupation world.

An Inherited Small Microdeletion at 15q13.3 in a Patient with Early- Onset Obsessive-Compulsive Disorder

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Chromosomal mapping of two Mariner-like elements in the grasshopper Abracris flavolineata (Orthoptera: Acrididae) reveals enrichment in euchromatin

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Retrospecto de lesões radiológicas da cabeça de cães e gatos

Pós-graduação em Cirurgia Veterinária - FCAV

The De-Totalization of History in Tim O'Brien's The Things They Carried

This paper aims at discussing how Tim O’Brien, a veteran of the Vietnam War, reviews the American involvement in the conflict in his novel The Things They Carried (1990). The author shows the perspective of the soldiers in the stories and, therefore, presents other possibilities to analyze that historical fact. The interplay of fiction and truth is essential for O’Brien to reach the objective of reevaluating official history in order to make the readers rethink the past.

The intricate role of mast cell proteases and the annexin A1-FPR1 system in abdominal wall endometriosis

Endometriosis is a continuous and progressive disease with a poorly understood aetiology, pathophysiology and natural history. This study evaluated the histological differences between eutopic and ectopic endometria (abdominal wall endometriosis) and the expression of mast cell proteases (tryptase and chymase), annexin A1 (ANXA1) and formyl peptide receptor 1 (FPR1). Ectopic endometrium from 18 women with abdominal wall endometriosis and eutopic endometrium from 10 women without endometriosis were obtained. The endometrial samples were analysed by histopathology, immunohistochemistry and ultrastructural immunogold labeling to determine mast cell heterogeneity (tryptase and chymase positive cells) and the expression levels of ANXA1 and FPR1. Histopathological analysis of the endometriotic lesions showed a glandular pattern of mixed differentiation and an undifferentiated morphology with a significant influx of inflammatory cells and a change in mast cell heterogeneity, as evidenced by a significant increase in the number of chymase-positive cells and endogenous chymase expression. The undifferentiated glandular pattern of endometriotic lesions was positively associated with a marked increase and co-localization of ANXA1 and FPR1 in the epithelial cells. In conclusion, the co-upregulated expression of mast cell chymase and ANXA1–FPR1 system in ectopic endometrium suggests their involvement in the development of endometriotic lesions.

Alterações cardiovasculares em pacientes com malária por Plasmodium vivax

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Expressão de microRNAs envolvidos com o crescimento muscular do pacu (Piaractus mesopotamicus): análises in vivo e in vitro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)