Estudo multicêntrico Brasileiro - Adesivo contraceptivo transdérmico semanal: Preferência e satisfação das usuárias

Background: To assess satisfaction with the weekly transdermal contraceptive patch, compared to the previous contraceptive method. Adhesion, cycle control, safety and efficacy were secondary outcomes. Methods: A multicenter, open label, descriptive study. Subjects received the weekly transdermal contraceptive patch for 6 cycles. At the baseline and after the 1 st, 3 rd and 6 th cycles, satisfaction with the method was assessed. The contraceptive efficacy was assessed by the Pearl Index and by life table analysis. Results: An ITT analysis was performed with 494 subjects. At the endpoint, 95.3% of women were satisfied with the patch compared to the previous method; 59.5%, 58.0% and 63.2% of women reported improvement in the physical and emotional well-being, and pre-menstrual symptoms, respectively. Pre-menstrual symptoms frequency decreased from 85.0% (CI 95%: 80.8-87.4%) to 55.0% (CI 95%: 49.9-66.0%). There was a significant increase in hemoglobin levels, and also a significant decrease in total serum cholesterol and tryglicerides.. There were no significant adverse events. The adjusted Pearl Index was 1.1 pregnancies per 100 women-years. Conclusions: The weekly contraceptive transdermal patch is a safe and effective method, and there was a high rate of satisfaction with its use among brazilian women. The patch was associated to a good cycle control, with easiness of use, improvement in the physical and emotional well-being and improvement in the premenstrual symptoms and lipid profile. © Copyright Moreira Jr. Editora. Todos os direitos reservados.

Raquianestesia contínua em paciente submetido à gastrectomia parcial. Relato de caso

BACKGROUND AND OBJECTIVES: Due to the high incidence of technical and neurological complications, continuous spinal blocks were not performed for several years. With the advent of intermediate catheters the technique has been used more often and gaining acceptance among anesthesiologists. The objective of this report was to demonstrate the usefulness of the technique as a viable alternative for medium and major size surgeries. CASE REPORT: This is a 58 years old female patient, weighing 62 kg, physical status ASA I, with a history of migraines, low back pain, and prior surgeries under spinal block without intercurrence. The patient was scheduled for exploratory laparotomy for a probable pelvic tumor. After venoclysis with an 18G catheter, monitoring with cardioscope, non-invasive blood pressure and pulse oximetry was instituted; she was sedated with 2 mg of midazolam and 100 μg of fentanyl, and placed in left lateral decubitus. The patient underwent continuous spinal block through the median approach in L 3-L 4; 9 mg of 0.5% hyperbaric bupivacaine and 120 μ g of morphine sulfate were administered. Inspection of the abdominal cavity revealed a gastric stromal tumor that required an increase in the incision for a partial gastrectomy. A small dose of hyperbaric solution was required for the entire procedure, which was associated with complete hemodynamic stability. Postoperative admission to the ICU was not necessary; the patient presented a good evolution without complaints and with a high degree of satisfaction. She was discharged from the hospital after 72 hours without intercurrence. CONCLUSIONS: Intermediate catheters used in continuous spinal blocks have shown the potential to turn it an attractive and useful technique in medium and large size surgeries and it can even be an effective alternative in the management of critical patients to whom hemodynamic repercussions can be harmful.

Geologia e Caracterização Tecnológica do Minério de Manganês da Mina Córrego do Cocho, Itapira (SP)

The objects of this study are three manganese ore deposits and one mine derived from lateritic weathering of gondites (spessartine quartzites). These deposits are associated with Mn-rich garnet metasediments of the Itapira Group (Paleoproterozoic) and the reserves were estimated at approximately 2.0 × 10 6 tons with an average grade of 23% MnO 2. The ore minerals are cryptomelane, pyrolusite, lithiophorite, spessartine and psilomelane. Several crystal shapes and textural characteristics were identifi ed in this study, which are related to the degree of liberation, as confi rmed by heavy media separation method. In this study, we determined the main characteristics of the liberation of manganese, which is concentrated in the fi ne grain-size fraction and is lost during ore dressing. Therefore, the low average content of MnO 2 (28%) is due to this loss, whereas at grain size of minus 0.074 mm, contents near 40% MnO 2 were observed. This suggests that the ore can be used for manufacturing manganese sulphate fertilizers. A comparative study with the ore deposits located at Ouro Fino (MG), mainly with the Caneleiras mine, showed that higher degree of liberation occurs in the coarse grain-size fractions (0.84 to 0.074 mm with MnO 2 content of 38%). As a consequence, the ore can be used for manufacturing Fe-Si-Mn alloys.

Evaluación del impacto de una intervención educativa en atención farmacéutica y farmacia clínica

Introduction: The World Health Organization considers pharmaceutical care (PC) of fundamental importance for the patient and the community. Its exercise requires knowledge and skills, which can be acquired in academic and/or continuing educations, credited for effectiveness and impact evaluation. However, few manuscripts in the literature have showed the contribution of the educational interventions on the knowledge, skill and attitude of students and professionals who participate in scientifi c events related to PC. Objective: To evaluate the impact of an educational intervention (EI), and its degree of satisfaction, to pharmacists and pharmacy students. Method: A quasi-experimental study was performed, through an extension course with 40 hours of lectures approaching issues related to PC and clinical pharmacy (CP). Participants answered a survey which was handed out before and after the EI. The statistic tests of Sinais and Mann-Whitney were applied to evaluate the EI signifi cance. Results: Participants (n= 49) were mostly (n= 34) students and performing activities related to PC and CP (n= 20). Statistics differences, before and after the EI, were found in the scores of knowledge, skill and attitude (p <0.001). The evaluated item which showed the most improvement was the last one. Most (n= 30) had exceeded or met their expectations (n= 19). Conclusions: The analysis of the data led us to conclude that an EI of 40 h/week about knowledge, skill and attitude in PC using traditional methods, improves knowledge and problem-solving skills of participants. ©2012 Ediciones Mayo, S.A. All rights reserved.

Transición de la movilidad: estudio de perfiles de migrantes de la tercera edad en el Brasil

Incluye Bibliografía

Leitura de jornais em famílias de estudantes de escola pública de ensino fundamental

Pós-graduação em Educação - FFC

As diferenças entre os desempenhos escolares, a relação com os saberes e o acesso à escrita: o que dizem professores e alunos de 5. série

Pós-graduação em Educação - IBRC

Segmentação de palavras: prosódia e convenções ortográficas na reelaboração da escrita infantil

Pós-graduação em Estudos Linguísticos - IBILCE

O vocabulário básico do português no processo de aquisição da língua materna

Pós-graduação em Estudos Linguísticos - IBILCE

As vogais pretônicas na fala culta do Noroeste Paulista

Pós-graduação em Estudos Linguísticos - IBILCE

Marcas de singularidade em textos escolares de alunos do 2º ano do ensino fundamental

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Desenvolvimento estético: entre as expectativas do professor e as possibilidades dos alunos

Pós-graduação em Artes - IA

Estudo comprarativo da biossorção dos metais terras-raras ('ND POT. +3', 'LA POT. +3', 'CE POT. +3') pela biomassa melanizada e pigmento, na forma livre e imobilizada, obtidos do fungo Aspergillus nidulans

Pós-graduação em Biotecnologia - IQ

Associação entre fatores epidemiológicos e neoplasias mamárias em cadelas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Imunorreatividade da prostaglandina E2 relacionada a classificação histológica, estadiamento clínico e prognóstico de neoplasias mamárias em cadelas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)