Inschriften des alten jüdischen Friedhofes in Wien : Beitrag zur Alterthumskunde Oesterreichs

von Ludw. Aug. Frankl

Konkordanz zum Targum Onkelos

hrsg. von Emil Brederek

Grammatik des Biblisch-Aramäischen : mit einer kritischen Erörterung der aramäischen Wörter im Neuen Testament

von E. Kautzsch

Rabbi Israel Lipkin Salant : sein Leben u. Wirken

dargest. von Emil Benjamin

Biblische Theologie des Alten Testaments

von D. Emil Kautzsch

Gabriel Riesser, ein Rechtsanwalt : Vortrag im Mendelssohn-Verein zu Dresden

geh. von Emil Lehmann

Der polnische Resident Berend Lehmann, der Stammvater der israelitischen Religionsgemeinde zu Dresden

von Emil Lehmann

Die Aramaismen im Alten Testament

unters. von E. Kautzsch

Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma.

Here we explore the role of the interplay between host immune response and epithelial-mesenchymal-transition (EMT)-Type tumor-budding on the outcome of pancreatic adenocarcinoma (PDAC).CD4+, CD8+, and FOXP3+T-cells as well as iNOS+ (M1) and CD163+- macrophages (M2) were assessed on multipunch tissue-microarrays containing 120 well-characterized PDACs, precursor lesions (PanINs) and corresponding normal tissue. Counts were normalized for the percentage of tumor/spot and associated with the clinico-pathological features, including peritumoral (PTB) and intratumoral (ITB) EMT-Type tumor-budding and outcome.Increased FOXP3+T-cell-counts and CD163-macrophages and decreased CD8+T-cell-counts were observed in PDACs compared with normal tissues and PanINs (p < 0.0001). Increased peritumoral FOXP3+T-cell-counts correlated significantly with venous invasion, distant metastasis, R1-status, high-grade ITB, PTB and independently with reduced survival. Increased intratumoral FOXP3+T-cells correlated with lymphatic invasion, N1-stage, PTB and marginally with adverse outcome. High peritumoral CD163-counts correlated with venous invasion, PTB and ITB. High intratumoral CD163-counts correlated with higher T-stage and PTB.PDAC-microenvironment displays a tumor-favoring immune-cell composition especially in the immediate environment of the tumor-buds that promotes further growth and indicates a close interaction of the immune response with the EMT-process. Increased peritumoral FOXP3+T-cell density is identified as an independent adverse prognostic factor in PDAC. Patients with phenotypically aggressive PDACs may profit from targeted immunotherapy against FOXP3.

Die Juden im bosporanischen Reiche und die Genossenschaften der sebomenoi theon hypsiston ebendaselbst

von Emil Schürer

O segne, Herr! : (Trauungslied) ; für Solo, Chor und Orgelbegleitung

componirt von Emil Brod

Anfang und Ende der Frankfurter Judengasse

Von Germanicus [d. i. Emil Richter]