The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement.

Routinely collected health data, obtained for administrative and clinical purposes without specific a priori research goals, are increasingly used for research. The rapid evolution and availability of these data have revealed issues not addressed by existing reporting guidelines, such as Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). The REporting of studies Conducted using Observational Routinely collected health Data (RECORD) statement was created to fill these gaps. RECORD was created as an extension to the STROBE statement to address reporting items specific to observational studies using routinely collected health data. RECORD consists of a checklist of 13 items related to the title, abstract, introduction, methods, results, and discussion section of articles, and other information required for inclusion in such research reports. This document contains the checklist and explanatory and elaboration information to enhance the use of the checklist. Examples of good reporting for each RECORD checklist item are also included herein. This document, as well as the accompanying website and message board (http://www.record-statement.org), will enhance the implementation and understanding of RECORD. Through implementation of RECORD, authors, journals editors, and peer reviewers can encourage transparency of research reporting.

Cost-benefit analysis of an enhanced recovery protocol for pancreaticoduodenectomy.

BACKGROUND: Enhanced recovery after surgery (ERAS) programmes have been shown to decrease complications and hospital stay. The cost-effectiveness of such programmes has been demonstrated for colorectal surgery. This study aimed to assess the economic outcomes of a standard ERAS programme for pancreaticoduodenectomy. METHODS: ERAS for pancreaticoduodenectomy was implemented in October 2012. All consecutive patients who underwent pancreaticoduodenectomy until October 2014 were recorded. This group was compared in terms of costs with a cohort of consecutive patients who underwent pancreaticoduodenectomy between January 2010 and October 2012, before ERAS implementation. Preoperative, intraoperative and postoperative real costs were collected for each patient via the hospital administration. A bootstrap independent t test was used for comparison. ERAS-specific costs were integrated into the model. RESULTS: The groups were well matched in terms of demographic and surgical details. The overall complication rate was 68 per cent (50 of 74 patients) and 82 per cent (71 of 87 patients) in the ERAS and pre-ERAS groups respectively (P = 0·046). Median hospital stay was lower in the ERAS group (15 versus 19 days; P = 0·029). ERAS-specific costs were euro922 per patient. Mean total costs were euro56 083 per patient in the ERAS group and euro63 821 per patient in the pre-ERAS group (P = 0·273). The mean intensive care unit (ICU) and intermediate care costs were euro9139 and euro13 793 per patient for the ERAS and pre-ERAS groups respectively (P = 0·151). CONCLUSION: ERAS implementation for pancreaticoduodenectomy did not increase the costs in this cohort. Savings were noted in anaesthesia/operating room, medication and laboratory costs. Fewer patients in the ERAS group required an ICU stay.

La prova del DNA nella pronuncia della Cassazione sul caso Amanda Knox e Raffaele Sollecito

Nell'annullamento della condanna di Amanda Knox e Raffaele Sollecito un ruolo centrale è stato assunto da alcune questioni connesse alla interpretazione delle tracce di DNA. L'articolo si focalizza su alcuni passaggi della sentenza della Corte di Cassazione, con specifico riferimento all'utilizzo e alla valutazione della prova genetica.

La Bouche de fer (Paris. 1790)

Variante(s) de titre : Cercle social

La Bouche de fer

1791 (T5).

La Bouche de fer

1791 (T1).

La Bouche de fer

1791 (T2).

La Bouche de fer

1790 (T2).

La Bouche de fer

1791 (T4).

La Bouche de fer

1790 (T1).

La Bouche de fer

1791 (T3).

Bulletin de la Bouche de fer

Périodicité : Irrégulier

Bulletin de la Bouche de fer

1790.

Gadolinska samlingen

Samlingen har varit kemiprofessorn Johan Gadolins (1760-1852) privatbibliotek. I samlingen ingår böcker som tillhört Johan Gadolins far, Jacob Gadolin (1719-1802), som var professor i fysik och teologi och sedemera biskop i Åbo stift. I samlingen ingår också böcker som tillhört Johan Gadolins morfar, Johan Browallius (1707-1755), som likaså var professor i fysik och teologi och sedemera biskop i Åbo stift. Samlingen är katalogiserad i Alma och har signum HB Gad.