Temporal changes in calcium-binding proteins in the medial geniculate nucleus of the monkey Sapajus apella

The subdivisions of the medial geniculate complex can be distinguished based on the immunostaining of calcium-binding proteins and by the properties of the neurons within each subdivision. The possibility of changes in neurochemistry in this and other central auditory areas are important aspects to understand the basis that contributing to functional variations determined by environmental cycles or the animal's cycles of activity and rest. This study investigated, for the first time, day/night differences in the amounts of parvalbumin-, calretinin- and calbindin-containing neurons in the thalamic auditory center of a non-human primate, Sapajus apella. The immunoreactivity of the PV-IR, CB-IR and CR-IR neurons demonstrated different distribution patterns among the subdivisions of the medial geniculate. Moreover, a high number of CB- and CR-IR neurons were found during day, whereas PV-IR was predominant at night. We conclude that in addition to the chemical heterogeneity of the medial geniculate nucleus with respect to the expression of calcium-binding proteins, expression also varied relative to periods of light and darkness, which may be important for a possible functional adaptation of central auditory areas to environmental changes and thus ensure the survival and development of several related functions.

Strategies for genotype imputation in composite beef cattle

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Linking natural supersymmetry to flavour physics

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Nanocompósitos multifuncionas de fibroína reforçados com biocelulose

This work shows the preparation and characterization of the new nanocomposites based on fibroin and biocellulose. Bacterial cellulose (BC) is an exopolysaccharide produced by bacteria of the genus Gluconacetobacter, which it has identical chemical structure of the cellulose from plants and it has gained attention in the field of research for its unique properties as excellent mechanical properties when dry and hydrated , higher capacity of water retention, moldability , biodegradability and excellent biological affinity . Silk fibroin (SF) is a structural protein present in the cocoon of the silkworm, Bombyx mori, has been identified as suitable for developing optical devices, tissue engineering application, enzyme immobilization, controlled release drug agent biopolymer. Silk fibroin/bacterial cellulose nanocomposite films were prepared impregnating different cellulose charges (0.5 %, 1.0 %, 1.5 %, 2.5 %, 5.0 % and 10.0 %) weight/weight. According mechanical tests and water and Paynes's cup permeability showed that SF/BC 1% nanocomposite has the most relevant results. Poliethylenoglicol (PEG) containing SF films improved optical and mechanical properties when compared to pristine SF film. New SF/BC nanocomposites could be applied in Medicine, as biodegradable packaging and flexible substrates for OLEDs.

Efeito da suplementação com boro no metabolismo ósseo de camundongos diabéticos não obesos

Pós-graduação em Alimentos e Nutrição - FCFAR

Mananas e glucanas em dietas para leitões recém-desmamados

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estilo de vida e saúde de um grupo de idosos de Franca, SP

The increase of elderly population in Brazil and all around the world shows the need of reviewing the health cares in order to get a better quality of life. Objective: To evaluate lifestyle and health care of elderly participants of UNATI, Franca, SP. Methods: Sixty elderlies answered a questions about socio-economic issues, health care, food consumption habits and lifestyle, after, they were submitted to anthropometric and laboratory tests. Results: There was a prevalence of women (85%), aged between 60-69 years old (60%), up to high school (60%), retired (65%), income up to 5 minimum wage (73.4%). Most seniors assessed medical care (65%) were in use of long-term medicines (78.3%), they reported to control blood pressure (80%) and to not smoke (100%). About 71.7% people believed to have a healthy diet, 97% took meals at home, 85% chose and prepared their own food, 65% had 5-6 meals/day, 63% drank 1L of water/day, 90% had bowel function and 43.3% practices a regular physical activity. Only 13.3% have done hormone replacement therapy, 18.3% take dietary supplements and 21.7% drink alcoholic drinks. The participants presented a BMI of 27.49 ± 4.5kg/m², prevalence of overweight and eutrophy, which values decreased with age. Leg circumference (LC) (36.27 ± 3.84 cm), Arm circumference (AC) (31.39 ± 4.08 cm) and triceps skinfolds (TS) (20.58±7.54mm) values were suit in most cases (96.7, 85 and 83.3%, respectively). Serum total cholesterol values were 198.53 ± 35.2mg/dL, 55% were considered optimum. About 63.3% and 68.3% of the elderlies, respectively, presented a high density lipoproteins (HDL) (53.58± 10.9mg/dL) and triglycerides (TG) (143.97 ± 92.37mg/dL) according to the recommendation and 51.7% of the elderlies had normal glycemia, 38.3% had risk and 10% showed high blood glucose, indicating diabetes. Conclusion: Many elderlies had body mass index (BMI) above normal, indicating overweight or obesity, but the participants can be considered healthy because of AC, LC and TS values, diet habits, health care and lifestyle.

Nanocompósitos de biocelulose e seu uso

A presente invenção refere-se ao desenvolvimento de um nanocompósito de biocelulose e dietilditiocarbamato (CB-DETC) que é formado por uma matriz polimérica de celulose bacteriana com nanofibras revestidas com derivados de dietilditiocarbamato no preparo de um biocurativo para o controle de Leishmaniose Tegumentar. As principais propriedades observadas nesse biocompósito são a sua flexibilidade, fácil aplicação em lesões cutâneas, capacidade leishmanicida, ausência de toxicidade e liberação sustentada do composto ativo, reduzindo a necessidade de troca do curativo.

Alterações antropométricas de lesados medulares após treinamento intervalado em natação

The goal of this study was to assess the alterations in some anthropometric measures of sedentary subjects with spinal cord injury after a swimming interval training program with the use of a lifejacket. The study included 17 male spinal cord injured subjects, divided into two groups: 11 subjects in the training group (TG) and 6 in the control group (CG).The protocol employed a stroke of breaststroke, in work periods of moderate to severe, and stroke in the back stroke in periods of active recovery. An anthropometric evaluation was applied before the application of the training protocol and another (reevaluation) after 8 weeks. In the TG, the results obtained after the swimming program showed a significant change (p < 0.05) in the supra-iliac (SICF) and in the triciptal cutaneous folds (TCF), arm and waist circumference measures, from the first evaluation to the reevaluation. In the CG there were no significant changes observed in any of the variables studied. When comparing the two groups after the swimming training program, the average of the variable SICFT in the TG was significantly lower than the average for the CG. Generally speaking, the out comings showed the swimming protocol efficiency in promoting desirable anthropometric changes in spinal cord injured subjects while a reduction of fatty tissue in the arms and abdominal region and an increase of muscular tissue in the upper limbs of those subjects also occurred.

Aprendizagem após via exclusão e formação de classes de equivalência em crianças com deficiência auditiva e implante coclear (aceito condicionalmente)

Studies on learning by exclusion have shown that participants tend to select a new object or a new figure when a new word is dictated, rejecting the objects and figures they already know or that were associated with other words. This study aimed at training conditional relations between dictated word-picture and between picture-printed word, by exclusion, and verify whether this training would be a condition for the emergence of relations between dictated word-printed word, printed word-figure, picture naming and reading. We also investigated whether responding to the words dictated with a female voice generalized to other frequencies such as male and child voices. Participants were five children between five and nine years old, with acute neurosensorial bilateral hearing impairment, users of cochlear implant Nucleus 24k®. They were exposed, individually, to tasks that consisted in selecting a comparison stimulus (either picture or printed word) related to the sample (either dictated word or picture). Words with lowest scores on a pre-test were used. The relations between dictated word-figure (AB) and figure-printed word (BC) were taught by exclusion. We assessed the emergence of the relations between dictated and printed words (AC), printed word and picture (CB), male and child voices generalization (A’C and A’’C), naming (BD) and reading (CD). All the children responded by exclusion and learned relations AB and BC, showing receptive vocabulary; AC and CB relations also were learned, consistent with class formation. Responding generalized to male and child voices, but data on naming were not systematic. Learning by exclusion was similar to that of children with typical hearing and these results describe some conditions that can improve receptive verbal repertoire.

Scaffold nanoestruturado utilizando-se celulose bacteriana/fosfatos de cálcio para regeneração óssea

Pós-graduação em Biotecnologia - IQ

Biodiversidade de parasitas de peixes da família Loricariidae (Teleostei: Siluriformes) procedentes do rio Sapucaí-Mirim, Brasil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análises físico-químicas e biológicas de diferentes scaffolds à base de polihidroxibutirato e polihidroxibutirato-co-valerato

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Membranas de biocelulose como substrato para o crescimento de nanofios de ZnO: síntese e aplicação

Pós-graduação em Química - IQ

Efficacy of Oral and Parenteral Routes of Mycobacterium bovis Bacille Calmette-Guerin Vaccination Against Experimental Bovine Tuberculosis in White-Tailed Deer (Odocoileus virginianus): A Feasibility Study

We investigated the efficacy of oral and parenteral Mycobacterium bovis bacille Calmette-Guerin Danish strain 1331 (BCG) in its ability to protect white-tailed deer (Odocoileus virginianus) against disease caused by M. bovis infection. Twenty-two white-tailed deer were divided into four groups. One group (n=5) received 109 colony-forming units (cfu) BCG via a lipid-formulated oral bait; one group (n=5) received 109 cfu BCG in culture directly to the oropharynx, one group (n=6) was vaccinated with 106 cfu BCG subcutaneously, and one group served as a control and received culture media directly to the oropharynx (n=6). All animals were challenged 3 mo after vaccination. Five months postchallenge the animals were examined for lesions. Results indicate that both oral forms of BCG and parenterally administerd BCG offered significant protection against M. bovis challenge as compared to controls. This study suggests that oral BCG vaccination may be a feasible means of controlling bovine tuberculosis in wild white-tailed deer populations.