A implantação do projeto de atendimento Móvel de Urgência em Salvador/BA: panorama e desafios

O estudo objetivou relatar a experiência na implantação e estruturação do projeto do Serviço Móvel de Urgência (SAMU-192), em Salvador, cujas bases legais foram portarias do Ministério da Saúde e a Norma Operacional de Assistência à Saúde 02/2002. O serviço tem como finalidade prestar assistência gratuita ao indivíduo, em um primeiro nível de atenção, com agravos de natureza clínica, cirúrgica, traumática e psiquiátrica que acarretam sofrimento, seqüelas ou morte e ocorrem fora do ambiente hospitalar. O objetivo específico foi garantir o atendimento às situações de urgência e emergência por meio do SAMU-192, regulado, hierarquizado e integrado ao Sistema Único de Saúde, assegurando recursos públicos inclusive integrados à rede complementar de assistência. Despesas para sua instalação foram pactuadas no município e em comissões intergestoras federal e estadual. Os desafios do serviço incluem educação comunitária, capacitação profissional, avaliação de recursos humanos e materiais, na dinâmica e qualidade da atenção.

Projecte d’intervenció Compartim i participem per créixer junts.

El projecte d’intervenció objecte d’aquest treball es desenvoluparà al municipi de Palau-solità i Plegamans, concretament amb el col•lectiu d’infants de 3 a 6 anys i els seus pares i mares. L’Ajuntament del municipi va fer l’encàrrec per a que es desenvolupés aquest projecte. Una de les temàtiques que aquesta administració vol incloure arreld’aquesta intervenció és la participació infantil, que serà la prioritat principal del projecte. Tot i això, s’inclouran altres temàtiques després de conèixer i analitzar lesopinions i demandes dels pares i mares d’infants de 3 a 6 anys a través d’una enquesta, creada específicament per aquesta intervenció, i les característiques i necessitats del desenvolupament vital d’aquests infants. La intervenció que es realitzarà amb aquest col•lectiu es dividirà en dos grups: per una banda, els infants i, per l’altra, els pares i mares d’aquests. Les temàtiques es dividiran en vuit sessions, en les que gran part d’aquestes es treballaran amb cada grup per separat però a gairebé totes les sessions es destinarà la part final a unir els dos grups per treballar de manera conjunta.

Presence of Chlamydiales DNA in ticks and fleas suggests that ticks are carriers of Chlamydiae.

The Chlamydiales order includes the Chlamydiaceae, Parachlamydiaceae, Waddliaceae, Simkaniaceae, Criblamydiaceae, Rhabdochlamydiaceae, Clavichlamydiaceae, and Piscichlamydiaceae families. Members of the Chlamydiales order are obligate intracellular bacteria that replicate within eukaryotic cells of different origins including humans, animals, and amoebae. Many of these bacteria are pathogens or emerging pathogens of both humans and animals, but their true diversity is largely underestimated, and their ecology remains to be investigated. Considering their potential threat on human health, it is important to expand our knowledge on the diversity of Chlamydiae, but also to define the host range colonized by these bacteria. Thus, using a new pan-Chlamydiales PCR, we analyzed the prevalence of Chlamydiales DNA in ticks and fleas, which are important vectors of several viral and bacterial infectious diseases. To conduct this study, 1340 Ixodes ricinus ticks prepared in 192 pools were collected in Switzerland and 55 other ticks belonging to different tick species and 97 fleas belonging to different flea species were harvested in Algeria. In Switzerland, the prevalence of Chlamydiales DNA in the 192 pools was equal to 28.1% (54/192) which represents an estimated prevalence in the 1340 individual ticks of between 4.0% and 28.4%. The pan-Chlamydiales qPCR was positive for 45% (25/55) of tick samples collected in Algeria. The sequencing of the positive qPCR amplicons revealed a high diversity of Chlamydiales species. Most of them belonged to the Rhabdochlamydiaceae and Parachlamydiaceae families. Thus, ticks may carry Chlamydiales and should thus be considered as possible vectors for Chlamydiales propagation to both humans and animals.

Long-term safety and effectiveness of lopinavir/ritonavir in antiretroviral-experienced HIV-1-infected children.

AIM: To evaluate the long-term safety and effectiveness of lopinavir/ritonavir (LPV/r) in a population-based cohort of HIV-1-infected children. METHODS: All children enrolled in the Swiss Mother and Child HIV Cohort Study, treated with LPV/r-based combination antiretroviral treatment (cART) between November 2000 and October 2008, were included. RESULTS: 88 children (25 (28%) protease inhibitor (PI)-naive, 16 (18%) ART-naive) were analysed (251 patient-years on LPV/r). After 48 weeks on LPV/r, 70 children had a median (interquartile range (IQR)) decrease in HIV-1 viral load of 4.25 log (5.45-3.17; PI-naive, n=17) and 2.53 (3.68-1.38; PI-experienced, n=53). Median (IQR) increase in CD4 count was 429 (203-593; PI-naive) and 177 (21-331; PI-experienced) cells/microl. These effects remained stable throughout 192 weeks for 25 children. Treatment was stopped for viral rebound in seven and suspected toxicity in 12 children. CONCLUSION: Long-term treatment with LPV/r-based cART is safe and effective in HIV-1-infected children.

[Archives de la Parole]. , El Gouali ; Ya Zellai / Maâllem Ali El Kdioui, ghaïtas [acc. perc.]

[Traditions. Afrique du Nord. Maroc]

[Archives de la Parole]. , Baïtan Hemdan ; Moual Resd Eddil / Mohamed Ben Hadj, chant [acc. instr.]

[Traditions. Afrique du Nord. Maroc]

Rates of cultural change and patterns of cultural accumulation in stochastic models of social transmission.

Cultural variation in a population is affected by the rate of occurrence of cultural innovations, whether such innovations are preferred or eschewed, how they are transmitted between individuals in the population, and the size of the population. An innovation, such as a modification in an attribute of a handaxe, may be lost or may become a property of all handaxes, which we call "fixation of the innovation." Alternatively, several innovations may attain appreciable frequencies, in which case properties of the frequency distribution-for example, of handaxe measurements-is important. Here we apply the Moran model from the stochastic theory of population genetics to study the evolution of cultural innovations. We obtain the probability that an initially rare innovation becomes fixed, and the expected time this takes. When variation in cultural traits is due to recurrent innovation, copy error, and sampling from generation to generation, we describe properties of this variation, such as the level of heterogeneity expected in the population. For all of these, we determine the effect of the mode of social transmission: conformist, where there is a tendency for each naïve newborn to copy the most popular variant; pro-novelty bias, where the newborn prefers a specific variant if it exists among those it samples; one-to-many transmission, where the variant one individual carries is copied by all newborns while that individual remains alive. We compare our findings with those predicted by prevailing theories for rates of cultural change and the distribution of cultural variation.

FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation.

Fas is a cell surface death receptor that signals apoptosis. Several proteins have been identified that bind to the cytoplasmic death domain of Fas. Fas-associated death domain (FADD), which couples Fas to procaspase-8, and Daxx, which couples Fas to the Jun NH(2)-terminal kinase pathway, bind independently to the Fas death domain. We have identified a 130-kD kinase designated Fas-interacting serine/threonine kinase/homeodomain-interacting protein kinase (FIST/HIPK3) as a novel Fas-interacting protein. Binding to Fas is mediated by a conserved sequence in the COOH terminus of the protein. FIST/HIPK3 is widely expressed in mammalian tissues and is localized both in the nucleus and in the cytoplasm. In transfected cell lines, FIST/HIPK3 causes FADD phosphorylation, thereby promoting FIST/HIPK3-FADD-Fas interaction. Although Fas ligand-induced activation of Jun NH(2)-terminal kinase is impaired by overexpressed active FIST/HIPK3, cell death is not affected. These results suggest that Fas-associated FIST/HIPK3 modulates one of the two major signaling pathways of Fas.

Sweetheart dance ; Lezginka : danse nationale / exécuté par l'orchestre de balalaïkas Kirilloff

[Traditions. Europe. Russie]

Aaqline-gel-Djzalere : chants kabyles ; Anel-áafouar-a-Sidi : chants kabyles / Amar Chaqual, chant ; avec Au Babas

[Traditions. Afrique du Nord. Algérie. Kabylie]

Naächequ lebnats : [Naʿšaq al-bn̄at] ; Marcha Djezireïa : [Marša Gazā iriyya] / Marie Soussan, chant [acc. orch.]. ; Edmond N. Yafil, dir.

[Traditions. Afrique du Nord. Algérie]

Adjouadi hadi : chant du Sud Oranais / par Chikh Hammada, chant [acc. instr.]

[Traditions. Afrique du Nord. Algérie]

Bba-sidi-bba-aouaâdi : chants berbères ; Iliouas-sbah-el-khire : chants kabyles / Amar Chaqual, avec Aubabas, chant

[Traditions. Afrique. Algérie]

Cuantos tormentos me dan : malaguenas del Cojo ; Todos te llaman la diosa / fandango ; por El Cojo de Málaga, chant ; con acompañamiento de guitarra por M. Borrull

[Traditions. Europe. Espagne. Andalousie]