991 resultados para Waste Products
Resumo:
Audit report on the Butler County Solid Waste Commission for the year ended June 30, 2009
Resumo:
Audit report on the Hardin County Sanitary Solid Waste Disposal Commission for the year ended June 30, 2009
Resumo:
Audit report on the Rural Iowa Waste Management Association for the year ended June 30, 2009
Resumo:
Audit report on the Wayne-Ringgold-Decatur County Solid Waste Management Commission for the year ended June 30, 2009
Resumo:
Audit report on the Jones County Solid Waste Management Commission for the year ended June 30, 2009
Resumo:
Audit report on the Pocahontas County Solid Waste Commission for the year ended June 30, 2009
Resumo:
Audit report on the Crawford County Area Solid Waste Agency Commission for the year ended June 30, 2009
Audit report on the Delaware County Solid Waste Disposal Commission for the year ended June 30, 2009
Resumo:
Audit report on the Delaware County Solid Waste Disposal Commission for the year ended June 30, 2009
Resumo:
Audit report on the Great River Regional Waste Authority for the year ended June 30, 2009
Resumo:
Tissue protein hypercatabolism (TPH) is a most important feature in cancer cachexia, particularly with regard to the skeletal muscle. The rat ascites hepatoma Yoshida AH-130 is a very suitable model system for studying the mechanisms involved in the processes that lead to tissue depletion, since it induces in the host a rapid and progressive muscle waste mainly due to TPH (Tessitore, L., G. Bonelli, and F. M. Baccino. 1987. Biochem. J. 241:153-159). Detectable plasma levels of tumor necrosis factor-alpha associated with marked perturbations in the hormonal homeostasis have been shown to concur in forcing metabolism into a catabolic setting (Tessitore, L., P. Costelli, and F. M. Baccino. 1993. Br. J. Cancer. 67:15-23). The present study was directed to investigate if beta 2-adrenergic agonists, which are known to favor skeletal muscle hypertrophy, could effectively antagonize the enhanced muscle protein breakdown in this cancer cachexia model. One such agent, i.e., clenbuterol, indeed largely prevented skeletal muscle waste in AH-130-bearing rats by restoring protein degradative rates close to control values. This normalization of protein breakdown rates was achieved through a decrease of the hyperactivation of the ATP-ubiquitin-dependent proteolytic pathway, as previously demonstrated in our laboratory (Llovera, M., C. García-Martínez, N. Agell, M. Marzábal, F. J. López-Soriano, and J. M. Argilés. 1994. FEBS (Fed. Eur. Biochem. Soc.) Lett. 338:311-318). By contrast, the drug did not exert any measurable effect on various parenchymal organs, nor did it modify the plasma level of corticosterone and insulin, which were increased and decreased, respectively, in the tumor hosts. The present data give new insights into the mechanisms by which clenbuterol exerts its preventive effect on muscle protein waste and seem to warrant the implementation of experimental protocols involving the use of clenbuterol or alike drugs in the treatment of pathological states involving TPH, particularly in skeletal muscle and heart, such as in the present model of cancer cachexia.
Resumo:
Audit report on the Rathbun Area Solid Waste Commission for the year ended June 30, 2010
Resumo:
Audit report on the Butler County Solid Waste Commission for the year ended June 30, 2010
Resumo:
Audit report on the Pocahontas County Solid Waste Commission for the year ended June 30, 2010
Resumo:
Audit report on the Shelby County Area Solid Waste Agency for the year ended June 30, 2010
