GABAA and GABAI Receptor Subunits Gene Expression and their Functional Role in Pilocarpine Induced Temporal Lobe Epilepsy

The research work which was carried out to characterization of wastes from natural rubber and rubber wood processing industries and their utilization for biomethanation. Environmental contamination is an inevitable consequence of human activity. The liquid and solid wastes from natural rubber based industries were: characterized and their use for the production of biogas investigated with a view to conserve conventional energy, and to mitigate environmental degradation.Rubber tree (flevea brasiliensis Muell. Arg.), is the most important commercial source of natural rubber and in india. Recently, pollution from the rubber processing factories has become very serious due to the introduction of modern methods and centralized group processing practices.The possibility of the use of spent slurry as organic manure is discussed.l0 percent level of PSD, the activity of cellulolytic, acid producing,proteolytic, lipolytic and methanogenic bacteria were more in the middle stage of methanogenesis.the liquid wastes from rubber processing used as diluents in combination with PSD, SPE promoted more biogas production with high methane content in the gas.The factors that favour methane production like TS, VS, cellulose and hemicellulose degradation were favoured in this treatment which led to higher methane biogenesis.The results further highlight ways and means to use agricultural wastes as alternative sources of energy.

Role of trace element of the growth and Physiology of selected microalgae

The main objective of the study is primarily to determine the magnitude of selected trace elements, the concentrations of which would possibly accelerate growth resulting in larger biomass and sustained period of exponential phase for economically viable harvest. The study on the effect of three trace elements namely Cu, Mn and Zn on two species of algae,ISOChrySiS galbana Parke and Synechocystib salina Wislouch under different conditions of salinity, PH and temperature involves several combinations for each metal, from which the relative set of conditions has been adduced. The scheme of the experiments was statistically designed for interpretation of data and factors were assessed and graded according to relative importance. The methodology adopted for data interpretation is analysis of variance by split-plot design method. The thesis has been divided into five chapters. The introductory chapter explains the relevance of the research work undertaken. Chapter 11 gives a review on the work pertaining to the above mentioned three trace elements in relation to nutrition as well as on the toxic aspects about which there is an abundance of literature. Chapter Ill presents a detailed description of the material and specialised methods followed for the study. The results and conclusions of the various experiments on effect of metals on growth and other physiological activities are discussed in Chapters IV and V.

Changing Role of Academic Libraries in the E-learning Environment: Issues and Challenges

The development of computer and network technology is changing the education scenario and transforming the teaching and learning process from the traditional physical environment to the digital environment. It is now possible to access vast amount of information online and enable one to one communication without the confines of place or time. While E-learning and teaching is unlikely to replace face-to-face training and education it is becoming an additional delivery method, providing new learning opportunities to many users. It is also causing an impact on library services as the increased use of ICT and web based learning technologies have paved the way for providing new ICT based services and resources to the users. Online learning has a crucial role in user education, information literacy programmes and in training the library professionals. It can help students become active learners, and libraries will have to play a greater role in this process of transformation. The significance of libraries within an institution has improved due to the fact that academic libraries and information services are now responsible for e-learning within their organization.

Emotional Intelligence As A Determinant Of Conflict Style Adoption Of Managers: A Theoretical Perspective

Successful management is dependent heavily on the manager’s ability to handle conflict effectively. The workforce has been increasingly becoming diversified vis-à-vis the gender, culture and ethnicity. The present work environment has in itself contributed to sowing seeds of conflict with greater diversity, hostility, complexity and newer business competencies in the work context.The classic study of Mintzberg’s Managerial roles approach (1973) also says that a manager has to spend sufficient time and energy in solving conflict as he has to take roles as a negotiator, and dispute handler. An understanding of the conflict and role that it plays in influencing employee behavior constructively or destructively is immense. Therefore conflict when left unmanaged can lead to diminished cohesiveness amongst employees, productivity and reduced organizational fitness. To manage conflict effective conflict resolution strategies that have constructive outcomes is called for. Conflict resolution style theorists opine that collaborative or integrative style, where there is high concern for task and people is considered to give positive individual and organizational outcomes, while the withdrawing /avoidance style and forcing / dominating style are considered to be ineffective in managing conflict. Though managers have typical preferences in the styles followed it need not necessarily be the typical response as it depends on the context, power relationships, emotions etc. The adoption of conflict styles of managers however is dependent on variables like gender orientation, cultural values, personality orientation, underlying relationships – public/private. The paper attempts to draw the importance of managing conflicts at workplace positively and the need for effective conflict resolution strategies. The conflict style adopted and the variables that affect the adoption of each style are discussed and possible interventions at the workplace are suggested

Landschaftsperspektiven der Nutzer

Die vorliegende Arbeit macht Vorschläge zur Einbindung der Öffentlichkeit in Planungsbestrebungen vor Ort, wobei vor allem Methoden empirischer Sozialforschung und deren Anwendbarkeit in landschaftsplanerischen Vorhaben näher betrachtet werden. Hiermit finden insbesondere Wertezuweisungen durch die Bürger stärkere Berücksichtigung. Es wird angenommen, dass, um eine zukunftsweisende Landschaftsplanung zu etablieren, Planer und Fachleute lernen müssen, wie die lokale Bevölkerung ihre Umwelt wahrnimmt und empfindet und welche Ideen sie für die zukünftige Entwicklung der Landschaft haben. Als empirische Grundlage werden Fallstudien aus Bad Soden am Taunus, Hamburg-Wilhelmsburg und Kassel-Rothenditmold präsentiert und verglichen. Rothenditmold und Wilhelmsburg zeichnen sich durch hohe Einwohneranteile mit Migrationshintergrund aus, weisen relativ hohe Arbeitslosenquoten auf und sind als soziale Brennpunkte bekannt – zumindest für Außenstehende. Beide Stadtteile versuchen ihr Image aufzuwerten. In Wilhelmsburg wird dieses Vorhaben in die großräumigen Veränderungen eingebunden, die von verschiedenen Hamburger Großprojekten ausstrahlen. In Rothenditmold ist vor allem Eigeninitiative durch den Stadtteil selbst gefragt. In Bad Soden gibt es ebenfalls viele Menschen mit ausländischen Wurzeln. Sie gehören allerdings mehrheitlich der gesellschaftlichen Mittel- und Oberschicht an. Bad Soden verfügt über ein insgesamt positives Image, das aller kulturellen Veränderungen zum Trotz beibehalten werden soll. Entsprechende Initiativen gehen hier ebenfalls von der Gemeinde selbst aus. An allen Standorten hat es drastische Landschaftsveränderungen und speziell deren Erscheinung gegeben. Bad Soden und Wilhelmsburg haben dabei Teile ihres vormals ländlichen Charakters zu bewahren, während in Rothenditmold vor allem Zeugnisse aus der Zeit der Industrialisierung erhalten sind und den Ort prägen. Die Landschaften haben jeweils ihre einzigartigen Erscheinungen. Zumindest Teile der Landschaften ermöglichen eine Identifikation, sind attraktiv und liefern gute Erholungsmöglichkeiten. Um diese Qualitäten zu bewahren, müssen sie entsprechend gepflegt und weiter entwickelt werden. Dazu sind die Interessen und Wünsche der Bewohner zu ermitteln und in Planungen einzuarbeiten. Die Arbeit strebt einen Beitrag zur Lebensraumentwicklung für und mit Menschen an, die mittels ausgewählter Methoden der empirischen Sozialforschung eingebunden werden. Dabei wird gezeigt, dass die vorgestellten und erprobten Methoden sinnvoll in Projekte der Landschaftsplanung eingebunden werden können. Mit ihnen können ergänzende Erkenntnisse zum jeweiligen Landschaftsraum gewonnen werden, da sie helfen, die kollektive Wahrnehmung der Landschaft durch die Bevölkerung zu erfassen, um sie anschließend in Planungsentwürfe einbinden zu können. Mit der Untersuchung wird in den drei vorgestellten Fallstudien exemplarisch erfasst, welche Elemente der Landschaft für die Bewohner von besonderer Bedeutung sind. Darüber hinaus lernen Planer, welche Methoden zur Ermittlung emotionaler Landschaftswerte verfügbar sind und auf welcher Ebene der Landschaftsplanung sowie bei welchen Zielgruppen sie eingesetzt werden können. Durch die Verknüpfung landschaftsplanerischer Erfassungsmethoden mit Methoden der empirischen Sozialwissenschaft (Fragebogen, Interviews, „Spaziergangsinterviews“, gemeinsame Erarbeitung von Projekten bis zur Umsetzung) sowie der Möglichkeit zur Rückkoppelung landschaftsplaneri-scher Entwürfe mit der Bevölkerung wird eine Optimierung dieser Entwürfe sowohl im Sinne der Planer als auch im Sinne der Bürger erreicht. Zusätzlich wird die Wahrnehmung teilnehmender Bevölkerung für ihre Umwelt geschärft, da sie aufgefordert wird, sich mit ihrer Lebensumgebung bewusst auseinander zu setzen. Die Ergebnisse dieser Untersuchung sind Beitrag und Beleg zu der Annahme, dass ergänzende Methoden in der Landschaftsplanung zur stärkeren Interessenberücksichtigung der von Planung betroffenen Menschen benötigt werden. Zudem zeigen die Studien auf, wie man dem planungsethischen Anspruch, die Öffentlichkeit einzubeziehen, näher kommt. Resultat sind eine bessere Bewertung und Akzeptanz der Planungen und das nicht nur aus landschaftsplanerisch-fachlicher Sicht. Landschaftsplaner sollten ein Interesse daran haben, dass ihre Entwürfe ernst genommen und akzeptiert werden. Das schaffen sie, wenn sie der Bevölkerung nicht etwas aufplanen, sondern ihnen entsprechende Einflussmöglichkeiten bieten und Landschaft mit ihnen gemeinsam entwickeln.

Capturing Emergent Semantics from Social Annotation Systems

The ongoing growth of the World Wide Web, catalyzed by the increasing possibility of ubiquitous access via a variety of devices, continues to strengthen its role as our prevalent information and commmunication medium. However, although tools like search engines facilitate retrieval, the task of finally making sense of Web content is still often left to human interpretation. The vision of supporting both humans and machines in such knowledge-based activities led to the development of different systems which allow to structure Web resources by metadata annotations. Interestingly, two major approaches which gained a considerable amount of attention are addressing the problem from nearly opposite directions: On the one hand, the idea of the Semantic Web suggests to formalize the knowledge within a particular domain by means of the "top-down" approach of defining ontologies. On the other hand, Social Annotation Systems as part of the so-called Web 2.0 movement implement a "bottom-up" style of categorization using arbitrary keywords. Experience as well as research in the characteristics of both systems has shown that their strengths and weaknesses seem to be inverse: While Social Annotation suffers from problems like, e. g., ambiguity or lack or precision, ontologies were especially designed to eliminate those. On the contrary, the latter suffer from a knowledge acquisition bottleneck, which is successfully overcome by the large user populations of Social Annotation Systems. Instead of being regarded as competing paradigms, the obvious potential synergies from a combination of both motivated approaches to "bridge the gap" between them. These were fostered by the evidence of emergent semantics, i. e., the self-organized evolution of implicit conceptual structures, within Social Annotation data. While several techniques to exploit the emergent patterns were proposed, a systematic analysis - especially regarding paradigms from the field of ontology learning - is still largely missing. This also includes a deeper understanding of the circumstances which affect the evolution processes. This work aims to address this gap by providing an in-depth study of methods and influencing factors to capture emergent semantics from Social Annotation Systems. We focus hereby on the acquisition of lexical semantics from the underlying networks of keywords, users and resources. Structured along different ontology learning tasks, we use a methodology of semantic grounding to characterize and evaluate the semantic relations captured by different methods. In all cases, our studies are based on datasets from several Social Annotation Systems. Specifically, we first analyze semantic relatedness among keywords, and identify measures which detect different notions of relatedness. These constitute the input of concept learning algorithms, which focus then on the discovery of synonymous and ambiguous keywords. Hereby, we assess the usefulness of various clustering techniques. As a prerequisite to induce hierarchical relationships, our next step is to study measures which quantify the level of generality of a particular keyword. We find that comparatively simple measures can approximate the generality information encoded in reference taxonomies. These insights are used to inform the final task, namely the creation of concept hierarchies. For this purpose, generality-based algorithms exhibit advantages compared to clustering approaches. In order to complement the identification of suitable methods to capture semantic structures, we analyze as a next step several factors which influence their emergence. Empirical evidence is provided that the amount of available data plays a crucial role for determining keyword meanings. From a different perspective, we examine pragmatic aspects by considering different annotation patterns among users. Based on a broad distinction between "categorizers" and "describers", we find that the latter produce more accurate results. This suggests a causal link between pragmatic and semantic aspects of keyword annotation. As a special kind of usage pattern, we then have a look at system abuse and spam. While observing a mixed picture, we suggest that an individual decision should be taken instead of disregarding spammers as a matter of principle. Finally, we discuss a set of applications which operationalize the results of our studies for enhancing both Social Annotation and semantic systems. These comprise on the one hand tools which foster the emergence of semantics, and on the one hand applications which exploit the socially induced relations to improve, e. g., searching, browsing, or user profiling facilities. In summary, the contributions of this work highlight viable methods and crucial aspects for designing enhanced knowledge-based services of a Social Semantic Web.

Moderating effects of management control systems and innovation on performance. Simple methods for correcting the effects of measurement error for interaction effects in small samples

In the accounting literature, interaction or moderating effects are usually assessed by means of OLS regression and summated rating scales are constructed to reduce measurement error bias. Structural equation models and two-stage least squares regression could be used to completely eliminate this bias, but large samples are needed. Partial Least Squares are appropriate for small samples but do not correct measurement error bias. In this article, disattenuated regression is discussed as a small sample alternative and is illustrated on data of Bisbe and Otley (in press) that examine the interaction effect of innovation and style of use of budgets on performance. Sizeable differences emerge between OLS and disattenuated regression

An Application of Augmented Reality (AR) in the Teaching of an Arc Welding Robot

Augmented Reality (AR) is an emerging technology that utilizes computer vision methods to overlay virtual objects onto the real world scene so as to make them appear to co-exist with the real objects. Its main objective is to enhance the user’s interaction with the real world by providing the right information needed to perform a certain task. Applications of this technology in manufacturing include maintenance, assembly and telerobotics. In this paper, we explore the potential of teaching a robot to perform an arc welding task in an AR environment. We present the motivation, features of a system using the popular ARToolkit package, and a discussion on the issues and implications of our research.

The Role of the online learner: onsite students becoming online learners

As universities are offering tuition through online learning environments, “onsite students” in higher education are increasingly becoming “online learners”. Since the medium for learning (and teaching) online is a digital environment, and at a distance, the role taken by students and teaching staff is different to the one these are used to in onsite, traditional settings. Therefore the Role of the Online Learner, presented in this paper, is key to onsite students who are to become online learners. This role consists of five competences: Operational, Cognitive, Collaborative, Self-directing, Course-specific. These five competences integrate the various skills, strategies, attitudes and awareness that make up the role of online learner, which learners use to perform efficiently online. They also make up the basis of a tutorial for would-be online learners, going over the Role of the Online Learner by means of concepts, examples and reflective activities. This tutorial, available to students in the author’s website, is also helpful to teaching and counselling staff in guiding their students to become online learners

The Personal tutorial guidance sessions in the framework of the teaching-learning field of the Bologna process: University of Minho (first cycle) courses students’ perceptions

The Bologna Process defends the adoption of a higher education in teaching-learning methodologies that – in contraposition to the previous model based on the transmission of knowledge, which for being essentially theoretical, gives the student a passive role in the knowledge construction process – allows a (pro) active, autonomous and practical learning, where the student acquires and develops his competences. The personal tutorial guidance sessions are included in the teaching contact hours. This abstract presents a study about the University of Minho (first cycle) Courses Students’ perceptions of the personal tutorial guidance sessions’ relevance in the scope of the learning-teaching process, so as to confirm if the implementation/implantation of the commonly called tutorial (type) education, as an approach to an active, autonomous and practical learning, is sensed by the learners themselves

El papel de la memoria de trabajo en el cálculo mental un cuarto de siglo después de Hitch = The role of working memory in mental arithmetic a quarter of century after Hitch

Desde que Hitch (1978) publicó el primer estudio sobre el rol de la memoria de trabajo en el cálculo han ido aumentando las investigaciones en este campo. Muchos trabajos han estudiado un único subsistema, pero nuestro objetivo es identificar qué subsistema de la memoria de trabajo (bucle fonológico, agenda viso-espacial o ejecutivo central) está más implicado en el cálculo mental. Para ello hemos realizado un estudio correlacional en el que hemos administrado dos pruebas aritméticas y nueve pruebas de la “Bateria de Test de Memòria de Treball” de Pickering, Baqués y Gathercole (1999) a una muestra de 94 niños españoles de 7-8 años. Nuestros resultados indican que el bucle fonológico y sobretodo el ejecutivo central inciden de forma estadísticamente significativa en el rendimiento aritmético

A Negotiation Style Recommender Based on Computational Ecology in Open Negotiation Environments

The system described herein represents the first example of a recommender system in digital ecosystems where agents negotiate services on behalf of small companies. The small companies compete not only with price or quality, but with a wider service-by-service composition by subcontracting with other companies. The final result of these offerings depends on negotiations at the scale of millions of small companies. This scale requires new platforms for supporting digital business ecosystems, as well as related services like open-id, trust management, monitors and recommenders. This is done in the Open Negotiation Environment (ONE), which is an open-source platform that allows agents, on behalf of small companies, to negotiate and use the ecosystem services, and enables the development of new agent technologies. The methods and tools of cyber engineering are necessary to build up Open Negotiation Environments that are stable, a basic condition for predictable business and reliable business environments. Aiming to build stable digital business ecosystems by means of improved collective intelligence, we introduce a model of negotiation style dynamics from the point of view of computational ecology. This model inspires an ecosystem monitor as well as a novel negotiation style recommender. The ecosystem monitor provides hints to the negotiation style recommender to achieve greater stability of an open negotiation environment in a digital business ecosystem. The greater stability provides the small companies with higher predictability, and therefore better business results. The negotiation style recommender is implemented with a simulated annealing algorithm at a constant temperature, and its impact is shown by applying it to a real case of an open negotiation environment populated by Italian companies

e-Research Methods Theme 1 Introduction

The theme will introduce you to research at the University of Southampton and within your School. It will also begin the process of helping you become more self- aware of your particular learning style to enable you to manage the requirements of the Research Methods module

Los conceptos de salud financiera, riesgo y epidemiología en los estados financieros de las compañías del sector de extracción de petróleo crudo y gas natural en Colombia

El presente proyecto tiene como objeto identificar cuáles son los conceptos de salud, enfermedad, epidemiología y riesgo aplicables a las empresas del sector de extracción de petróleo y gas natural en Colombia. Dado, el bajo nivel de predicción de los análisis financieros tradicionales y su insuficiencia, en términos de inversión y toma de decisiones a largo plazo, además de no considerar variables como el riesgo y las expectativas de futuro, surge la necesidad de abordar diferentes perspectivas y modelos integradores. Esta apreciación es pertinente dentro del sector de extracción de petróleo y gas natural, debido a la creciente inversión extranjera que ha reportado, US$2.862 millones en el 2010, cifra mayor a diez veces su valor en el año 2003. Así pues, se podrían desarrollar modelos multi-dimensional, con base en los conceptos de salud financiera, epidemiológicos y estadísticos. El termino de salud y su adopción en el sector empresarial, resulta útil y mantiene una coherencia conceptual, evidenciando una presencia de diferentes subsistemas o factores interactuantes e interconectados. Es necesario mencionar también, que un modelo multidimensional (multi-stage) debe tener en cuenta el riesgo y el análisis epidemiológico ha demostrado ser útil al momento de determinarlo e integrarlo en el sistema junto a otros conceptos, como la razón de riesgo y riesgo relativo. Esto se analizará mediante un estudio teórico-conceptual, que complementa un estudio previo, para contribuir al proyecto de finanzas corporativas de la línea de investigación en Gerencia.

Role of the cultural values as a key part in the implementing of healthy practices : exploratory research

El concepto de organización saludable cada vez toma más fuerza en el ámbito empresarial y académico, a razón de su enfoque integral y al impacto generado en distintos grupos de interés. Debido a su reciente consolidación como concepto, existe un limitado cuerpo de investigación en torno al tema. Para contribuir a la generación de conocimiento en este sentido, se desarrolló un estudio exploratorio el cual tenía como objetivo identificar la relación existente entre la implementación de prácticas saludables en las organizaciones y los valores culturales. En el estudio participaron 66 sujetos a quienes se les administró un cuestionario compuesto por nueve variables, cinco provenientes del modelo de Hofstede (1980) y cuatro más que evaluaban la implementación de prácticas organizacionales saludables. Los resultados obtenidos muestran que los valores culturales predicen la implementación de prácticas saludables.