Microfluidic effects of transporting signaling components in cell coculture chips

A theoretical model has been developed to investigate the microfluidic transport of the signaling chemicals in the cell coculture chips. Using an epidermal growth factor (EGF)-like growth factor as the sample chemical, the effects of velocities and channel geometry were studied for the continuous-flow microchannel bioreactors. It is found that different perfusion velocities must be applied in the parallel channels to facilitate the communication, i.e., transport of the signaling component, between the coculture channels. Such communication occurs in a unidirectional way because the signaling chemicals can only flow from the high velocity area to the low velocity area. Moreover, the effect of the transport of the signaling component between the coculture channels on the growth of the monolayer cells and the multicellular tumor spheroid (MTS) in the continuous-flow coculture environment were simulated using 3D models. The numerical results demonstrated that the concentration gradients will induce the heterogeneous growth of the cells and the MTSs, which should be taken into account in designing the continuous-flow perfusion bioreactor for the cell coculture research.

Materiales Condensados y con Estructura Abierta basados en Fosfitos de Metales 3d

438 p.

Sistema de comercio electrónico para el sector textil: generar maniquíes 3D a partir de imágenes del sensor Kinect

Este proyecto consiste en analizar la viabilidad técnica un sistema de información para mejorar el comercio electrónico de compra –venta de ropa. El nuevo sistema de comercio electrónico ayudará al usuario a escoger el tamaño de la prenda con más precisión. El sistema consiste en calcular las medidas esenciales del cuerpo del cliente utilizando el dispositivo Kinect. Posteriormente, estas medidas se introducen en el programa Makehuman que genera un maniquí en 3D. Con la idea de que en el futuro se puede utilizar el maniquí para probar virtualmente prendas de vestir, se ha ideado un método, utilizando el programa Blender, que genera ropa en 3D con fotografías de prendas. Se generan dos ejemplos (pantalón y camiseta) para ilustrarlo.