De joodsche gemeente van Amersfoort : Gedenkschrift samengest. ter gelegenheid van het 2. eeuwfeest van haar synagoge ; 5487:1727 - 5607:1927

door Jac. Zwarts

De bezoeken van Gacham Azulay aan Nederland in de tweede helft der 18de eeuw

door J. S. Da Silva Rosa

De eerste rabbijnen en synagogen van Amsterdam : naar archivalischen bronnen

door Jac. Zwarts

Verslag uitgebragt in de openbare vergadering van het Nederlandsch-Israelitisch armbestuur te Amsterdam

door I. T. Philips

De kolonisatie van de Portugeesch Joodsche Natie in Suriname en de geschiedenis von de Joden Savanne

door Fred. Oudschans Dentz

Wat is toch de Talmud? En wat ist een Talmud-jood? : Iets uit en over de verderfelijke geloofspunten en praktijken van het jodendom

door August Rohling. Geheel herzien en verbeterd door Max. de Lamarque

Vier hebreeuwsche gezangen : voor kinderstemmen, ten dienste van scholen, syngagogen enz.

gemponeerd door A. Berlijn. De tekst bewerkt onder opzigt van G. I. Polak

Cross-sectional study of 168 patients with hepatorenal tyrosinaemia and implications for clinical practice

BackgroundHepatorenal tyrosinaemia (Tyr 1) is a rare inborn error of tyrosine metabolism. Without treatment, patients are at high risk of developing acute liver failure, renal dysfunction and in the long run hepatocellular carcinoma. The aim of our study was to collect cross-sectional data.MethodsVia questionnaires we collected retrospective data of 168 patients with Tyr 1 from 21 centres (Europe, Turkey and Israel) about diagnosis, treatment, monitoring and outcome. In a subsequent consensus workshop, we discussed data and clinical implications.ResultsEarly treatment by NTBC accompanied by diet is essential to prevent serious complications such as liver failure, hepatocellular carcinoma and renal disease. As patients may remain initially asymptomatic or develop uncharacteristic clinical symptoms in the first months of life newborn mass screening using succinylacetone (SA) as a screening parameter in dried blood is mandatory for early diagnosis. NTBC-treatment has to be combined with natural protein restriction supplemented with essential amino acids. NTBC dosage should be reduced to the minimal dose allowing metabolic control, once daily dosing may be an option in older children and adults in order to increase compliance. Metabolic control is judged by SA (below detection limit) in dried blood or urine, plasma tyrosine (<400 ¿M) and NTBC-levels in the therapeutic range (20¿40 ¿M). Side effects of NTBC are mild and often transient.Indications for liver transplantation are hepatocellular carcinoma or failure to respond to NTBC. Follow-up procedures should include liver and kidney function tests, tumor markers and imaging, ophthalmological examination, blood count, psychomotor and intelligence testing as well as therapeutic monitoring (SA, tyrosine, NTBC in blood).ConclusionBased on the data from 21 centres treating 168 patients we were able to characterize current practice and clinical experience in Tyr 1. This information could form the basis for clinical practice recommendations, however further prospective data are required to underpin some of the recommendations.

Hebreeuwsche nomenclator : zijnde een bundel van Hebreeuwsche woorden, spreuken enzamenspraken

voor D. A. Lissaur

Handelende van de bedieninge des tempels : zoo di was in de daagen van de zaligmaaker en korts voo de verstooringe van jerusalem

nieuwijx agtervolgd op de 2 stuk, eertijds uitgeg. door W[illem] Goeree

Keur van grafsteenen op de Nederl.-Portug.-Israe͏̈l. begraafplaats te Ouderkerk aan den Amstel met beschrijving en biographische aanteekeningen : tot inleiding een en ander over deze en de vroegere begraafplaats der Nederl.-Portug.-Israe͏̈l. gemeente te Amsterdam ; eerste bundel

von D. Henriques de Castro

Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation.

AIMS In this work, we provide novel insight into the morphology of dissecting abdominal aortic aneurysms in angiotensin II-infused mice. We demonstrate why they exhibit a large variation in shape and, unlike their human counterparts, are located suprarenally rather than infrarenally. METHODS AND RESULTS We combined synchrotron-based, ultra-high resolution ex vivo imaging (phase contrast X-Ray tomographic microscopy) with in vivo imaging (high-frequency ultrasound and contrast-enhanced micro-CT) and image-guided histology. In all mice, we observed a tear in the tunica media of the abdominal aorta near the ostium of the celiac artery. Independently we found that, unlike the gradual luminal expansion typical for human aneurysms, the outer diameter increase of angiotensin II-induced dissecting aneurysms in mice was related to one or several intramural haematomas. These were caused by ruptures of the tunica media near the ostium of small suprarenal side branches, which had never been detected by the established small animal imaging techniques. The tear near the celiac artery led to apparent luminal dilatation, while the intramural haematoma led to a dissection of the tunica adventitia on the left suprarenal side of the aorta. The number of ruptured branches was higher in those aneurysms that extended into the thoracic aorta, which explained the observed variability in aneurysm shape. CONCLUSION Our results are the first to describe apparent luminal dilatation, suprarenal branch ruptures, and intramural haematoma formation in dissecting abdominal aortic aneurysms in mice. Moreover, we validate and demonstrate the vast potential of phase contrast X-ray tomographic microscopy in cardiovascular small animal applications.

Chronologisch handboekje voor de geschiedenis der Israeliten van de schepping der wereld tot op onzen tijd

uit de deloofwaardigste bronnen bearb. door S. I. Mulder