Delectus florae et faunae brasiliensis : jussu et auspiciis Francisci I. Austriae Imperatoris investigatae

Delectus Florae et faunae brasiliensis é uma obra ricamente ilustrada, que contém vinte e quatro lâminas com cinquenta e quatro figuras representando espécies da flora e da fauna brasileira. A obra, publicada em Viena, foi realizada sob os auspícios do Imperador Francisco I da Áustria, configurando uma parte dos resultados da expedição científica ao Brasil de que o autor participou.

Press, politic, and social order in Buenos Aires during the 1850s

The paper examines some reflections and discussions about the role and nature of the press that took place in Buenos Aires during the 1850s, referring to the difficulties involved in congenial freedom and order. This was caused by the fact that the press was considered a pillar of republican and civilized societies, but also an agent capable of corroding the social and political order.

Cultura política, actores e discursos nos alvores do Liberalismo : revisitar a revolução de 1821 nos Açores

O presente estudo consiste numa análise da cultura política no início do Liberalismo em Portugal, centrada sobre os deputados micaelenses nas Cortes Portuguesas que emergiram da revolução liberal de 1820 e, por outro lado, numa revisitação da revolução de 1821 em Ponta Delgada. Nesse contexto, a proposta de projecto apresentada por um dos deputados que visava a abolição dos vínculos na ilha de São Miguel e nos Açores foi o mote para esta dissertação. Visitamos a conjuntura de outro espaço atlântico na mesma época, a Madeira, de modo a conduzirmos uma avaliação comparativa, mantendo o quadro atlântico em perspectiva. Recorremos, por fim, à biografia de um deputado para obtermos uma escala de observação mais próxima da dinâmica política.

Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine in HIV-infected adults on combination antiretroviral therapy: a phase I/II, randomized trial.

OBJECTIVE: Tuberculosis (TB) is highly prevalent among HIV-infected people, including those receiving combination antiretroviral therapy (cART), necessitating a well tolerated and efficacious TB vaccine for these populations. We evaluated the safety and immunogenicity of the candidate TB vaccine M72/AS01 in adults with well controlled HIV infection on cART. DESIGN: A randomized, observer-blind, controlled trial (NCT00707967). METHODS: HIV-infected adults on cART in Switzerland were randomized 3 : 1 : 1 to receive two doses, 1 month apart, of M72/AS01, AS01 or 0.9% physiological saline (N = 22, N = 8 and N = 7, respectively) and were followed up to 6 months postdose 2 (D210). Individuals with CD4⁺ cell counts below 200 cells/μl were excluded. Adverse events (AEs) including HIV-specific and laboratory safety parameters were recorded. Cell-mediated (ICS) and humoral (ELISA) responses were evaluated before vaccination, 1 month after each dose (D30, D60) and D210. RESULTS: Thirty-seven individuals [interquartile range (IQR) CD4⁺ cell counts at screening: 438-872 cells/μl; undetectable HIV-1 viremia] were enrolled; 73% of individuals reported previous BCG vaccination, 97.3% tested negative for the QuantiFERON-TB assay. For M72/AS01 recipients, no vaccine-related serious AEs or cART-regimen adjustments were recorded, and there were no clinically relevant effects on laboratory safety parameters, HIV-1 viral loads or CD4⁺ cell counts. M72/AS01 was immunogenic, inducing persistent and polyfunctional M72-specific CD4⁺ T-cell responses [medians 0.70% (IQR 0.37-1.07) at D60] and 0.42% (0.24-0.61) at D210, predominantly CD40L⁺IL-2⁺TNF-α⁺, CD40L⁺IL-2⁺ and CD40L⁺IL-2⁺TNF-α⁺IFN-γ⁺]. All M72/AS01 vaccines were seropositive for anti-M72 IgG after second vaccination until study end. CONCLUSION: M72/AS01 was clinically well tolerated and immunogenic in this population, supporting further clinical evaluation in HIV-infected individuals in TB-endemic settings.

Sylloge nova epistolarum varii argumenti. Volume 2 / . Volumen I-[V]

Comprend : Observatio de nummis romanis in quibus S. C. et EX S. C. notatum legitur

Sylloge nova epistolarum varii argumenti. Volume 3 / . Volumen I-[V]

Comprend : Observatio de nummis romanis in quibus S. C. et EX S. C. notatum legitur

Sylloge nova epistolarum varii argumenti. Volume 5 / . Volumen I-[V]

Comprend : Observatio de nummis romanis in quibus S. C. et EX S. C. notatum legitur

Sylloge nova epistolarum varii argumenti. Volume 4 / . Volumen I-[V]

Comprend : Observatio de nummis romanis in quibus S. C. et EX S. C. notatum legitur

Sylloge nova epistolarum varii argumenti. Volume 1 / . Volumen I-[V]

Comprend : Observatio de nummis romanis in quibus S. C. et EX S. C. notatum legitur

Sylloge nova epistolarum varii argumenti. Volume 1, Partie 2 / . Volumen I-[V]

Comprend : Observatio de nummis romanis in quibus S. C. et EX S. C. notatum legitur

The Bee Newspaper, Vol. I, No. 13

An original Niagara area newspaper containing an account of the Battle of Queenston Heights and the death and burial of Sir Isaac Brock. The newspaper is dated October 24, 1812, eleven days after the death of General Brock. Topics of interest include: Page 1: Sheaffe announcement regulating the sale of alcohol in Niagara; Myers announcement asking citizens for the return of American muskets recovered from the battle at Queenston; local notices on business claims and education; want ads for wood, straw, flour and pork for military use; announcement by the Prince Regent in Council putting an embargo on American ships. Page 2: release of American prisoners captured at Queenston; news of the British Navy; the security of Canadian properties in wartime; American ships leaving Britain with licenses. Page 3: American ships leaving Britain with licenses Page 4: report on the Battle of Queenston Heights and the death of Isaac Brock.

Historia de Querétaro, 1821-1870 : documentos

UANL

Proceso del Señor Dn. Agustín de Iturbide Libertador y Primer Emperador de México.

UANL

Resúmen histórico de la Revolución de los Estados Unidos Mejicanos, sacada del Cuadro histórico que en forma de cartas escribió el Lic. D. Carlos María Bustamante; i ordenado en cuatro libros por D. Pablo de Menditil.

UANL