A legislação ambiental aplicada nas áreas de preservação permanente da microbacia do Ribeirão Duas Águas - Botucatu (SP)

O trabalho visou obter o uso do solo da microbacia do Ribeirão Duas Águas – Botucatu (SP), através de imagem de satélite, a determinação das Áreas de Preservação Permanentes (APPs) e os conflitos existentes na área. As bases cartográficas foram: a carta planialtimétrica em formato digital do IBGE de 1969 e imagem de satélite de 2011. O SIG-IDRISI Selva foi utilizado para realizar o georreferenciamento da imagem, geração dos buffer de APPs e o overlay para obtenção dos conflitos de uso além da confecção do mapa temático final. No CartaLinx foi feita a delimitação da área de estudo e dos elementos (da rede de drenagem e das áreas de uso e cobertura). O uso da terra mostrou que a microbacia vem sendo ocupada por 1149,67ha de florestas naturais; 1073,45ha de reflorestamento; 737,67ha de pastagens; 691,93ha com solo exposto e 132,33ha de campo sujo. Já quanto as APPs, elas correspondem a 366,34ha de toda a microbacia, e destas 89,32ha estãosendo usadas para outros fins evidenciando assim seu conflito de uso. Desta forma, a caracterização do uso e cobertura da terra da região possibilitou uma infinidade de informações sobre a tipologia de manejo aplicado e na identificação de problemas ambientais que se configuram em decorrência de seu uso. Quanto aos conflitos em APPs uma parte significante da área da microbacia está sendo utilizada inadequadamente, não respeitando a legislação do Código Florestal Brasileiro.

Geoprocessamento aplicado na caracterização morfométrica da microbacia do Ribeirão Descalvado - Botucatu (SP)

The objective of this study was to evaluate geoprocessing to morphometrically characterize the Ribeirão Descalvado micro watershed – Botucatu, SP by the Geographic Information System (GIS) – Selva for preservation, rationalization of its use and environmental restoration. The micro watershed is 2,228.61 ha between the geographic coordinates: 22° 50' 05" to 22° 54' 26" latitude S and 48° 22' 29" to 48° 26' 36" longitude W Gr. The cartographic basis was the planialtimetric chart of Botucatu (SP), 1: 50000 scale (IBGE, 1969), used for extraction of level, hydrography and topography curves to determine morphometric indices. The results showed that low values of drainage density associated with the presence of permeable rocks facilitates ground water infiltration which decreases surface runoff, erosion risks and environmental degradation. The low value of the shape factor supported by the circularity index shows that the micro watershed is more elongated and at lower risk of more pronounced floods. The roughness coefficient environmental parameter classified the micro watershed for forest and reforestation.

Mapeamento, erodibilidade e tolerância de perdas de solo na sub-bacia do Ribeirão das Perobas

The land use conservation planning requires knowledge of the soil characteristics, natural susceptibility to erosion and the soil loss limit. In this context, the objectives of this study were to perform a detailed soil survey of Ribeirão das Perobas watershed, located in Santa Cruz do Rio Pardo, São Paulo State and to determine and map the erodibility and soil loss tolerance of the soil classes found in the survey. The following techniques were used to perform the detailed soil survey: photopedology, field sampling, physical analysis, chemical analysis, and morphological description of the soil samples and profiles. The erodibility was determined by the methods described by Denardin (1990) and Mannigel et al. (2002), and the determination of soil loss tolerance followed the methodology of Mannigel et al. (2002). The results of erodibility determined by the methodology of Denardin (1990) were not discrepant and they did not distinguish soils that are known to have different susceptibility to erosion., w\Whereas, using the methodology of Mannigel et al. (2002), very high or very low erodibility values were observed in soils with extreme contents of sand silt or clay. The most influent variable to the soil loss tolerance results was the correction factor for the textural gradient of clay between soil horizons.

Avaliação das áreas de conflito de uso em APP na microbacia do ribeirão Morro Grande

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Formação continuada de professores: curso Melhor Gestão, Melhor Ensino em quatro escolas de Batatais - Diretoria de Ensino de Ribeirão Preto

Pós-graduação em Planejamento e Análise de Políticas Públicas - FCHS

Capitalismo, trabalho e formação profissional: dilemas do trabalho cotidiano dos assistentes sociais em Ribeirão Preto, São Paulo

Pós-graduação em Serviço Social - FCHS

As lógicas espaciais do sistema bancário: reestruturação das cidades de Marília, Ribeirão Preto e São Carlos

Esa tesis presenta un breve histórico sobre el sistema bancario brasileño, buscando entender las lógicas espaciales en tres ciudades paulistas - Marília, Ribeirão Preto y São Carlos - asociando el abordaje, sobretodo, al contexto de las ciudades intermedias, que es el caso de las las ciudades estudiadas en esta investigación. Realizamos este análisis a través del trabajo con algunas hipótesis sobre lógicas espaciales, refuerzo de la centralidad urbana y nuevas tendencias, con el fin de comprender posibles prácticas espaciales resultantes de reestruturacción urbana y de la ciudad, tomando en consideración que la fuerte presencia de distintas agencias, junto a los espacios comerciales de las ciudades, confirma la importancia comercial que estas ciudades tienen, revelando relaciones entre su ubicación y las posibilidades de atraer usuarios. Por lo tanto, el estudio de las lógicas espaciales ejecutadas por los grandes grupos que operan el sistema bancario ha tenido papel importante en la articulación entre reestruturación urbana y de las ciudades

Delimitação, intensidade e especialização de áreas comerciais: uma proposição para o estudo das áreas centrais em cidades médias a partir da análise dos Índices de Densidade Informacional para os casos de Presidente Prudente - SP e Ribeirão Preto - SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

As lógicas espaciais do sistema bancário: reestruturação das cidades de Marília, Ribeirão Preto e São Carlos

Esa tesis presenta un breve histórico sobre el sistema bancario brasileño, buscando entender las lógicas espaciales en tres ciudades paulistas - Marília, Ribeirão Preto y São Carlos - asociando el abordaje, sobretodo, al contexto de las ciudades intermedias, que es el caso de las las ciudades estudiadas en esta investigación. Realizamos este análisis a través del trabajo con algunas hipótesis sobre lógicas espaciales, refuerzo de la centralidad urbana y nuevas tendencias, con el fin de comprender posibles prácticas espaciales resultantes de reestruturacción urbana y de la ciudad, tomando en consideración que la fuerte presencia de distintas agencias, junto a los espacios comerciales de las ciudades, confirma la importancia comercial que estas ciudades tienen, revelando relaciones entre su ubicación y las posibilidades de atraer usuarios. Por lo tanto, el estudio de las lógicas espaciales ejecutadas por los grandes grupos que operan el sistema bancario ha tenido papel importante en la articulación entre reestruturación urbana y de las ciudades

Delimitação, intensidade e especialização de áreas comerciais: uma proposição para o estudo das áreas centrais em cidades médias a partir da análise dos Índices de Densidade Informacional para os casos de Presidente Prudente - SP e Ribeirão Preto - SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Evaluation of Radiopacity, pH, Release of Calcium Ions, and Flow of a Bioceramic Root Canal Sealer

Introduction: The aim of the present study was to evaluate the physicochemical properties of a bioceramic root canal sealer, Endosequence BC Sealer. Radiopacity, pH, release of calcium ions (Ca2+), and flow were analyzed, and the results were compared with AH Plus cement. Methods: Radiopacity and flow were evaluated according to ISO 6876/2001 standards. For the radiopacity analysis, metallic rings with 10-mm diameter and 1-mm thickness were filled with cements. The radiopacity value was determined according to radiographic density (mm Al). The flow test was performed with 0.05 mL of cement placed on a glass plate. A 120-g weight was carefully placed over the cement. The largest and smallest diameters of the disks formed were measured by using a digital caliper. The release of Ca2+ and pH were measured at periods of 3, 24, 72, 168, and 240 hours with spectrophotometer and pH meter, respectively. Data were analyzed by analysis of variance and Tukey test (P < .05). Results: The bioceramic endodontic cement showed radiopacity (3.84 mm Al) significantly lower than that of AH Plus (6.90 mm Al). The pH analysis showed that Endosequence BC Sealer showed pH and release of Ca2+ greater than those of AH Plus (P < .05) during the experimental periods. The flow test revealed that BC Sealer and AH Plus presented flow of 26.96 mm and 21.17 mm, respectively (P < .05). Conclusions: Endosequence BC Sealer showed radiopacity and flow according to ISO 6876/2001 recommendations. The other physicochemical properties analyzed demonstrated favorable values for a root canal sealer. (J Endod 2012;38:842-845)

The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food

The hosts for Antricola delacruzi ticks are insectivorous, cave-dwelling bats on which only larvae are found. The mouthparts of nymphal and adult A. delacruzi are compatible with scavenging feeding because the hypostome is small and toothless. How a single blood meal of a larva provides energy for several molts as well as for oviposition by females is not known. Adults of A. delacruzi possibly feed upon an unknown food source in bat guano, a substrate on which nymphal and adult stages are always found. Guano produced by insectivorous bats contains twice the amount of protein and 60 times the amount of iron as beef. In addition, bacteria and chitin-rich fungi proliferate on guano. Comparative data on the transcriptome of the salivary glands of A. delacruzi is nonexistent and would help to understand the physiological adaptations of salivary glands that accompany different sources of food as well as the steps taken by the Acari toward haematophagy, believed to have evolved from scavenging dead animals. Annotation of the transcriptome of salivary glands from female instars of A. delacruzi collected on guano categorized 5.7% of the clusters of expressed genes as putative secreted proteins. They included abundantly expressed TIL-domain-containing proteins (possible anti-microbials), an abundantly expressed protein similar to a serum amyloid found in the sialotranscriptomes of Ornithodoros spp., a savignygrin, a family of mucin/peritrophin/cuticle-like proteins, anti-microbials and an HIV envelope-like glycoprotein also found in soft ticks. When comparing the transcriptome of A. delacruzi with those of blood-feeding female soft and hard ticks some notable differences were observed; they consisted of the following transcripts over- or under-represented or absent in the sialotranscriptome of A. delacruzi that may reflect its source of food: ferritin, mucins with chitin-binding domains and TIL-domain-containing proteins versus lipocalins, basic tail proteins, metalloproteases, glycine-rich proteins and Kunitz protease inhibitors, respectively. (C) 2012 Elsevier Ltd. All rights reserved.

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.

Expression of BAG-1 and PARP-1 in Precursor Lesions and Invasive Cervical Cancer Associated with Human Papillomavirus (HPV)

Cervical cancer remains persistently the second most common malignancies among women worldwide, responsible for 500,000 new cases annually. Only in Brazil, the estimate is for 18,430 new cases in 2011. Several types of molecular markers have been studied in carcinogenesis including proteins associated with apoptosis such as BAG-1 and PARP-1. This study aims to demonstrate the expression of BAG-1 and PARP-1 in patients with low-grade squamous intraepithelial lesions (LSILs), high-grade squamous intraepithelial lesions (HSILs) and invasive squamous cell carcinomas (SCCs) of the uterine cervix and to verify a possible association with HPV infection. Fifty samples of LSILs, 50 samples of HSILs and 50 samples of invasive SCCs of the uterine cervix were analyzed by immunohistochemistry for BAG-1 and PARP-1 expression. PCR was performed to detect and type HPV DNA. BAG-1 expression levels were significantly different between LSILs and HSILs (p = 0,014) and between LSILs and SCCs (p = 0,014). In regards to PARP-1 expression, we found significant differences between the expression levels in HSILs and SCCs (p = 0,022). No association was found between BAG-1 expression and the presence of HPV. However, a significant association was found between PARP-1 expression and HPV positivity in the HSILs group (p = 0,021). In conclusion our research suggests that BAG-1 expression could contribute to the differentiation between LSIL and HSIL/SCC whereas PARP-1 could be useful to the differentiation between HSIL HPV-related and SCC. Further studies are needed to clarify the molecular aspects of the relationship between PARP-1 expression and HPV infection, with potential applications for cervical cancer prediction.

Doença isquêmica do coração e fatores associados em adultos de Ribeirão Preto, SP

OBJETIVO: Identificar a prevalência da doença isquêmica do coração em adultos e fatores associados. MÉTODOS: Estudo epidemiológico transversal de base populacional, conduzido em amostra ponderada de 2.471 adultos de ambos os sexos e com 30 anos ou mais residentes em Ribeirão Preto, SP, em 2007. A prevalência da doença foi estimada por pontos e por intervalos com 95% de confiança (IC95%), após a aplicação do Questionário Rose. Para a identificação de fatores associados (fatores sociodemográficos, de riscos cardiovasculares e relacionados ao acesso a serviços e ao padrão de atividade física), razões de prevalências brutas e ajustadas foram estimadas por meio da regressão de Poisson. RESULTADOS: A prevalência de doença isquêmica do coração foi maior no sexo feminino que no masculino, em todas as faixas etárias. No modelo final permaneceram independentemente associadas ao desfecho as seguintes variáveis: ter trabalho (RP = 0,54 [0,37;0,78]); antecedentes familiares de doença isquêmica do coração (RP = 1,55 [1,12;2,13]); hipertensão arterial (RP = 1,70 [1,18;2,46]); saúde autorreferida (RP = 2,15 [1,40;3,31]); duração do hábito de fumar (3° terço) (RP = 1,73 [1,08;2,76]); circunferência da cintura alterada (RP = 1,79 [1,21;2,65]) e hipertrigliceridemia (RP = 1,48 [1,05;2,10]). Teste de tendência linear para as RP nas categorias da variável saúde autorreferida apresentou significância estatística (p < 0,05). CONCLUSÕES: Além da elevada prevalência de doença isquêmica do coração, os fatores associados ao desfecho são quase todos modificáveis e passíveis de intervenção por meio de políticas públicas.