Report on a special investigation of the Malvern Public Library for the period July 1, 2006 through October 31, 2013

Report on a special investigation of the Malvern Public Library for the period July 1, 2006 through October 31, 2013

A guide to resources for the study of the recent history of the United States in the libraries of the University of Iowa, the State Historical Society of Iowa, and in the Herbert Hoover Presidential Library, 1977

This guide is designed as a finding aid for researchers seeking materials on a particular topic and it indicates the nature and extent of resources for the study of United States history available at the Historical Society of Iowa, the Herbert Hoover Presidential Library and the Iowa University Libraries.

Iowa Library Services FY12 Annual Report, June 2013

Annual report for State Library of Iowa

Iowa Library Services FY13 Annual Report, June 2014

Annual report for State Library of Iowa

Apport des modèles expérimentaux: associations Synercid et beta-lactamines

SYNERCID ALONE IN A RAT MODEL OF EXPERIMENTAL ENDOCARDITIS: Trials conducted using 2 injections daily showed that animals infected with meti-R resistant Staphylococcus aureus strains sensitive to erythromycin were cured in 3 days. The same is not true for infections caused by C-MLSB-R staphylococci. The daily dose cannot be increased due to the venous toxicity of Synercid, leading to the idea of testing Synercid in combination with other antibiotics. IN VITRO STUDIES: Several antibiotics have been tested in combination with Synercid. Several beta-lactams have been shown to exhibit an additive or synergetic effect on a collection of meti-R and meti-S S. aureus strains. IN VIVO STUDIES: In animals infected with C-MLSB-R meti-R S. aureus, the combination Synercid + cefepime increases the activity of cefipime and prevents selection of beta-lactam highly resistant strains. The results obtained with the Synercid + cefpirome combination are even more eloquent. Finally, Synercid, alone or in combination with these 2 cephalosporins, does not select resistant strains.

Iowa DOT Library Services, Collection, & Technology Assessment, TR-670, 2014

Assesses the impact of library services on research projects, proposes methods to improve the impact of library services on research projects, assesses current library technology systems and proposes upgrades, assesses current library collection infrastructure and propose upgrades, especially in regards to collection damage from water or fire; ascertains patron interest in mobile technologies and suggest development based on interest.

Shall a free public library be established? : Iowa public library laws, 1914

This leaflet gives information on how to start a free public library in a community. Includes regulations and related laws dealing with libraries.

The study club program : suggestions relating to courses of study and aids furnished by the Traveling Library, 1909

This leaflet includes information on programs for Women's Clubs. Some possible subjects for the club's discussions are literature, history and fine arts. Several methods of study are covered. Groups are encouraged to use public libraries and the Iowa Traveling Library to obtain reference materials for their topics.

Books for the blind : loaned by the Iowa Library Commission, 1914

This leaflet gives information on the Iowa Library Commission and the added service of the circulation of books for the blind to the Traveling Library. Their goal is to make books available to every blind person who desires books.

Library buildings : Selection of an architect ... A paper read before the Iowa Library Association at Grinnell, Iowa. October 30, 1902

This leaflet talks about the architecture of library buildings. It provides information on the selection of an architect and how to design flooring and room arrangements in a practical way.

Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases

AbstractBACKGROUND: Scientists have been trying to understand the molecular mechanisms of diseases to design preventive and therapeutic strategies for a long time. For some diseases, it has become evident that it is not enough to obtain a catalogue of the disease-related genes but to uncover how disruptions of molecular networks in the cell give rise to disease phenotypes. Moreover, with the unprecedented wealth of information available, even obtaining such catalogue is extremely difficult.PRINCIPAL FINDINGS: We developed a comprehensive gene-disease association database by integrating associations from several sources that cover different biomedical aspects of diseases. In particular, we focus on the current knowledge of human genetic diseases including mendelian, complex and environmental diseases. To assess the concept of modularity of human diseases, we performed a systematic study of the emergent properties of human gene-disease networks by means of network topology and functional annotation analysis. The results indicate a highly shared genetic origin of human diseases and show that for most diseases, including mendelian, complex and environmental diseases, functional modules exist. Moreover, a core set of biological pathways is found to be associated with most human diseases. We obtained similar results when studying clusters of diseases, suggesting that related diseases might arise due to dysfunction of common biological processes in the cell.CONCLUSIONS: For the first time, we include mendelian, complex and environmental diseases in an integrated gene-disease association database and show that the concept of modularity applies for all of them. We furthermore provide a functional analysis of disease-related modules providing important new biological insights, which might not be discovered when considering each of the gene-disease association repositories independently. Hence, we present a suitable framework for the study of how genetic and environmental factors, such as drugs, contribute to diseases.AVAILABILITY: The gene-disease networks used in this study and part of the analysis are available at http://ibi.imim.es/DisGeNET/DisGeNETweb.html#Download

Iowa Library Trustee's Handbook, 2014

Gives trustees a basic understanding of their responsibilities and power.

Iowa Library Services/State Library Update, January 2015, Vol. 13, no. 1

Quarterly update for Iowa Library Services/State Library patrons.