Nanoinformatics knowledge infrastructures: bringing efficient information management to nanomedical research

Nanotechnology represents an area of particular promise and significant opportunity across multiple scientific disciplines. Ongoing nanotechnology research ranges from the characterization of nanoparticles and nanomaterials to the analysis and processing of experimental data seeking correlations between nanoparticles and their functionalities and side effects. Due to their special properties, nanoparticles are suitable for cellular-level diagnostics and therapy, offering numerous applications in medicine, e.g. development of biomedical devices, tissue repair, drug delivery systems and biosensors. In nanomedicine, recent studies are producing large amounts of structural and property data, highlighting the role for computational approaches in information management. While in vitro and in vivo assays are expensive, the cost of computing is falling. Furthermore, improvements in the accuracy of computational methods (e.g. data mining, knowledge discovery, modeling and simulation) have enabled effective tools to automate the extraction, management and storage of these vast data volumes. Since this information is widely distributed, one major issue is how to locate and access data where it resides (which also poses data-sharing limitations). The novel discipline of nanoinformatics addresses the information challenges related to nanotechnology research. In this paper, we summarize the needs and challenges in the field and present an overview of extant initiatives and efforts.

PÓS-GRADUAÇÃO, PRODUÇÃO ACADÊMICA, INTERDISCIPLINARIDADE E SOCIALIZAÇÃO DO CONHECIMENTO: A PRODUÇÃO CIENTÍFICA DO GRANDE ABC À LUZ DO PNPG 2011-2020

O objetivo desta investigação foi verificar se, diante da autonomia e vocação que possuem, bem como da possibilidade de receber amparo e incentivos governamentais, as universidades pertencentes à região do Grande ABC atenderam as recomendações feitas pelo PNPG vigente. Para tanto, foram analisadas cinquenta e sete dissertações e duas teses da área de ciências sociais aplicadas, publicadas no período entre 2011 e 2014, pelas seguintes instituições: Universidade Metodista de São Paulo (UMESP); Universidade Municipal de São Caetano do Sul (USCS); Universidade Federal do ABC (UFABC) e Faculdade de Engenharia Industrial (FEI). Essa averiguação se deu ao redor de dois eixos organizadores do PNPG 2011-2014: o terceiro eixo – o aperfeiçoamento da avaliação e sua expansão para outros segmentos do sistema de CT&I (formação de pós-graduados voltados para atividades extra-acadêmicas/setor empresarial) e o quarto eixo – a multi e a interdisciplinaridade entre as principais características da pós-graduação e importantes temas da pesquisa (promover, por meio de programas, áreas de concentração e linhas de pesquisa, a convergência de temas e compartilhamento de problemas em oposição à sua mera associação ou sobreposição). Este estudo – qualitativo, bibliográfico, documental, exploratório, descritivo, tipo estado do conhecimento – se desenvolveu por meio de pesquisa documental e de análise de conteúdo temático categorial. A coleta de dados foi feita por meio dos repositórios digitais de teses e dissertações mantidos na internet pelas Universidades, cuja produção científica foi investigada. Após a análise dos dados ficou demonstrado que aproximadamente 68,96% da produção científica da área de ciências sociais aplicadas, publicada pelas universidades do Grande ABC, no período entre 2011 e 2014, corresponde às expectativas do PNPG atual no que diz respeito às recomendações constantes no terceiro eixo. Em relação às recomendações feitas no texto do quarto eixo, vemos que aproximadamente 31,03% dos trabalhos selecionados atendem às expectativas do Plano, apresentando em sua estrutura, segundo a fundamentação teórica utilizada neste trabalho, características de interdisciplinaridade.

PÓS-GRADUAÇÃO, PRODUÇÃO ACADÊMICA, INTERDISCIPLINARIDADE E SOCIALIZAÇÃO DO CONHECIMENTO: A PRODUÇÃO CIENTÍFICA DO GRANDE ABC À LUZ DO PNPG 2011-2020

O objetivo desta investigação foi verificar se, diante da autonomia e vocação que possuem, bem como da possibilidade de receber amparo e incentivos governamentais, as universidades pertencentes à região do Grande ABC atenderam as recomendações feitas pelo PNPG vigente. Para tanto, foram analisadas cinquenta e sete dissertações e duas teses da área de ciências sociais aplicadas, publicadas no período entre 2011 e 2014, pelas seguintes instituições: Universidade Metodista de São Paulo (UMESP); Universidade Municipal de São Caetano do Sul (USCS); Universidade Federal do ABC (UFABC) e Faculdade de Engenharia Industrial (FEI). Essa averiguação se deu ao redor de dois eixos organizadores do PNPG 2011-2014: o terceiro eixo – o aperfeiçoamento da avaliação e sua expansão para outros segmentos do sistema de CT&I (formação de pós-graduados voltados para atividades extra-acadêmicas/setor empresarial) e o quarto eixo – a multi e a interdisciplinaridade entre as principais características da pós-graduação e importantes temas da pesquisa (promover, por meio de programas, áreas de concentração e linhas de pesquisa, a convergência de temas e compartilhamento de problemas em oposição à sua mera associação ou sobreposição). Este estudo – qualitativo, bibliográfico, documental, exploratório, descritivo, tipo estado do conhecimento – se desenvolveu por meio de pesquisa documental e de análise de conteúdo temático categorial. A coleta de dados foi feita por meio dos repositórios digitais de teses e dissertações mantidos na internet pelas Universidades, cuja produção científica foi investigada. Após a análise dos dados ficou demonstrado que aproximadamente 68,96% da produção científica da área de ciências sociais aplicadas, publicada pelas universidades do Grande ABC, no período entre 2011 e 2014, corresponde às expectativas do PNPG atual no que diz respeito às recomendações constantes no terceiro eixo. Em relação às recomendações feitas no texto do quarto eixo, vemos que aproximadamente 31,03% dos trabalhos selecionados atendem às expectativas do Plano, apresentando em sua estrutura, segundo a fundamentação teórica utilizada neste trabalho, características de interdisciplinaridade.

Mesure de la performance dans les organisations de réadaptation en déficience physique

La présente thèse vise à évaluer le degré d’implantation et d’utilisation de systèmes de mesure de la performance (SMP) par les décideurs des organisations de réadaptation et à comprendre les facteurs contextuels ayant influencé leur implantation. Pour ce faire, une étude de cas multiples a été réalisée comprenant deux sources de données: des entrevues individuelles avec des cadres supérieurs des organisations de réadaptation du Québec et des documents organisationnels. Le cadre conceptuel Consolidated Framework for Implementation Research a été utilisé pour guider la collecte et l’analyse des données. Une analyse intra-cas ainsi qu’une analyse inter-cas ont été réalisées. Nos résultats montrent que le niveau de préparation organisationnelle à l’implantation d’un SMP était élevé et que les SMP ont été implantés avec succès et utilisés de plusieurs façons. Les organisations les ont utilisés de façon passive (comme outil d’information), de façon ciblée (pour tenter d’améliorer des domaines sous-performants) et de façon politique (comme outil de négociation auprès des autorités gouvernementales). Cette utilisation diversifiée des SMP est suscitée par l’interaction complexe de facteurs provenant du contexte interne propre à chaque organisation, des caractéristiques du SMP, du processus d’implantation appliqué et du contexte externe dans lequel évoluent ces organisations. Au niveau du contexte interne, l’engagement continu et le leadership de la haute direction ont été décisifs dans l’implantation du SMP de par leur influence sur l’identification du besoin d’un SMP, l’engagement des utilisateurs visés dans le projet, la priorité organisationnelle accordée au SMP ainsi que les ressources octroyées à son implantation, la qualité des communications et le climat d’apprentissage organisationnel. Toutefois, même si certains de ces facteurs, comme les ressources octroyées à l’implantation, la priorité organisationnelle du SMP et le climat d’apprentissage se sont révélés être des barrières à l’implantation, ultimement, ces barrières n’étaient pas suffisamment importantes pour entraver l’utilisation du SMP. Cette étude a également confirmé l’importance des caractéristiques du SMP, particulièrement la perception de qualité et d’utilité de l’information. Cependant, à elles seules, ces caractéristiques sont insuffisantes pour assurer le succès d’implantation. Cette analyse d’implantation a également révélé que, même si le processus d’implantation ne suit pas des étapes formelles, un plan de développement du SMP, la participation et l’engagement des décideurs ainsi que la désignation d’un responsable de projet ont tous facilité son implantation. Cependant, l’absence d’évaluation et de réflexion collective sur le processus d’implantation a limité le potentiel d’apprentissage organisationnel, un prérequis à l’amélioration de la performance. Quant au contexte externe, le soutien d’un organisme externe s’est avéré un facilitateur indispensable pour favoriser l’implantation de SMP par les organisations de réadaptation malgré l’absence de politiques et incitatifs gouvernementaux à cet effet. Cette étude contribue à accroître les connaissances sur les facteurs contextuels ainsi que sur leurs interactions dans l’utilisation d’innovations tels les SMP et confirme l’importance d’aborder l’analyse de l’implantation avec une perspective systémique.

Post-Ottoman Coexistence : Sharing Space in the Shadow of Conflict /

"Post-Ottoman Coexistence", interrogates ways of living together and asks what practices enabled centuries of cooperation and sharing, as well as how and when such sharing was disrupted. This title was made Open Access by libraries from around the world through Knowledge Unlatched.

Digital Classics Outside the Echo-Chamber : Teaching, Knowledge Exchange and Public Engagement /

The international perspectives on these issues are especially valuable in an increasingly connected, but still institutionally and administratively diverse world. The research addressed in several chapters in this volume includes issues around technical standards bodies like EpiDoc and the TEI, engaging with ways these standards are implemented, documented, taught, used in the process of transcribing and annotating texts, and used to generate publications and as the basis for advanced textual or corpus research. Other chapters focus on various aspects of philological research and content creation, including collaborative or community driven efforts, and the issues surrounding editorial oversight, curation, maintenance and sustainability of these resources. Research into the ancient languages and linguistics, in particular Greek, and the language teaching that is a staple of our discipline, are also discussed in several chapters, in particular for ways in which advanced research methods can lead into language technologies and vice versa and ways in which the skills around teaching can be used for public engagement, and vice versa. A common thread through much of the volume is the importance of open access publication or open source development and distribution of texts, materials, tools and standards, both because of the public good provided by such models (circulating materials often already paid for out of the public purse), and the ability to reach non-standard audiences, those who cannot access rich university libraries or afford expensive print volumes. Linked Open Data is another technology that results in wide and free distribution of structured information both within and outside academic circles, and several chapters present academic work that includes ontologies and RDF, either as a direct research output or as essential part of the communication and knowledge representation. Several chapters focus not on the literary and philological side of classics, but on the study of cultural heritage, archaeology, and the material supports on which original textual and artistic material are engraved or otherwise inscribed, addressing both the capture and analysis of artefacts in both 2D and 3D, the representation of data through archaeological standards, and the importance of sharing information and expertise between the several domains both within and without academia that study, record and conserve ancient objects. Almost without exception, the authors reflect on the issues of interdisciplinarity and collaboration, the relationship between their research practice and teaching and/or communication with a wider public, and the importance of the role of the academic researcher in contemporary society and in the context of cutting edge technologies. How research is communicated in a world of instant- access blogging and 140-character micromessaging, and how our expectations of the media affect not only how we publish but how we conduct our research, are questions about which all scholars need to be aware and self-critical.

Should the knowledge-based economy be a savant or a sage? Wisdom and socially intelligent innovation

Discourse about knowledge-based economies rarely moves beyond the commercialization of science and engineering, and is locked in the discursive limits of functionalism. We argue that these discourses limit the scope of what knowledge-based economies might achieve because they are uninformed by an adequate conception of knowledge. In particular, knowledge management and knowledge-based economy discourse has not included the axiological dimension of knowledge that leads to wisdom. Taking an axiological perspective, we can discuss policy frameworks aimed at producing the social structures needed to bring fully formed and fully functioning knowledge societies into being. We argue that while the dominant discourse of industrial modernity remains rationalist, functionalist, utilitarian and technocratic, knowledge-based economies will resemble a savant rather than a sage. A wisdom-based renaissance of humanistic epistemology is needed to avoid increasing social dysfunction and a lack of wisdom in complex technological societies.

Modelling knowledge production performance of research centres with a focus on triple bottom line benchmarking

We demonstrate a portable process for developing a triple bottom line model to measure the knowledge production performance of individual research centres. For the first time, this study also empirically illustrates how a fully units-invariant model of Data Envelopment Analysis (DEA) can be used to measure the relative efficiency of research centres by capturing the interaction amongst a common set of multiple inputs and outputs. This study is particularly timely given the increasing transparency required by governments and industries that fund research activities. The process highlights the links between organisational objectives, desired outcomes and outputs while the emerging performance model represents an executive managerial view. This study brings consistency to current measures that often rely on ratios and univariate analyses that are not otherwise conducive to relative performance analysis.

A flaw in the use of minimal defining sets for secret sharing schemes

It is shown that in some cases it is possible to reconstruct a block design D uniquely from incomplete knowledge of a minimal defining set for D. This surprising result has implications for the use of minimal defining sets in secret sharing schemes.

Managing knowledge in tourism planning: How to assess your capability

This paper explores the theme of strategic planning in a State Tourism Organization (STO) from a knowledge management perspective. It highlights the value of knowledge in strategy making and the importance of an organisation's knowledge management agenda in facilitating a strategic planning process. In particular, it considers the capability of an STO to implement knowledge management as the key to a successful strategic planning exercise. In order to develop greater insight into the factors that impact on planning competence, the key aim of this paper is to develop a framework on which the capability of a STO to implement a knowledge-based agenda in strategic planning can be assessed. Research on knowledge management in the field of tourism is limited and there is little practical account of the application of knowledge management principles in tourism planning. Further, there is no apparent tool or instrument that allows for the assessment of an STO's capability to implement knowledge management in planning initiatives. Based on a literature review, a three-point framework of assessment is developed. The three elements of the framework are identified as: 1. Integration of knowledge management objectives with strategic imperatives; 2. A planning approach that balances top-down (outcome focused) with bottom-up (process focused) planning processes; and 3. Organisational capacity, including leadership, people and culture, process, technology, content and continuous improvement. The framework is tested through application to a practical case study - a planning initiative undertaken by a leading tourism STO in Australia. The results demonstrate that the framework is a useful means to evaluate organisational capability in knowledge-led strategic planning exercises and would be of practical value as a point of reference for future knowledge- based strategic planning projects. Copyright © by The Haworth Press, Inc. All rights reserved.

Creating an authentic aural experience in the digital songlines game engine: Part of a contextualised cultural heritage knowledge toolkit

Digital Songlines is an Australasian CRC for Interaction Design (ACID) project that is developing protocols, methodologies and toolkits to facilitate the collection, education and sharing of indigenous cultural heritage knowledge. The project explores the areas of effective recording, content management and virtual reality delivery capabilities that are culturally sensitive and involve the indigenous custodians, leaders and communities in remote areas of the Australian ‘outback’. It investigates how players in a serious gaming sense can experience Indigenous virtual heritage in a high fidelity fashion with culturally appropriate interface tools. This paper describes a 3D ambient audio quilt designed and implemented specifically for the Digital Songlines software, which is built using the Torque Game Engine. The audio quilt developed provides dynamic ambient fauna and flora sound effects to represent the varying audio environment of the landscape. This provides an authentic contextualised interesting aural experience that can be different each time a location is entered. This paper reports on completed and ongoing research in this area.