888 resultados para Exploration and exploitation
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Cardiac tissue engineering (CTE) is currently a prime focus of research due to an enormous clinical need. In this work, a novel functional material, Poly(3-hydroxyoctanoate), P(3HO), a medium chain length polyhydroxyalkanoate (PHA), produced using bacterial fermentation, was studied as a new potential material for CTE. Engineered constructs with improved mechanical properties, crucial for supporting the organ during new tissue regeneration, and enhanced surface topography, to allow efficient cell adhesion and proliferation, were fabricated. Our results showed that the mechanical properties of the final patches were close to that of cardiac muscle. Biocompatibility of the P(3HO) neat patches, assessed using Neonatal ventricular rat myocytes (NVRM), showed that the polymer was as good as collagen in terms of cell viability, proliferation and adhesion. Enhanced cell adhesion and proliferation properties were observed when porous and fibrous structures were incorporated to the patches. Also, no deleterious effect was observed on the adults cardiomyocytes’ contraction when cardiomyocytes were seeded on the P(3HO) patches. Hence, P(3HO) based multifunctional cardiac patches are promising constructs for efficient CTE. This work will provide a positive impact on the development of P(3HO) and other PHAs as a novel new family of biodegradable functional materials with huge potential in a range of different biomedical applications, particularly CTE, leading to further interest and exploitation of these materials.
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Salman, M. et al. (2016). Integrating Scientific Publication into an Applied Gaming Ecosystem. GSTF Journal on Computing (JoC), Volume 5 (Issue 1), pp. 45-51.
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Royal Proclamation prohibiting the printing and publishing of ecclesiastical and other books without prior licence, as well as the importation, sale and publication of English language texts printed on the continent. This Proclamation established the precedent for the pre-publication licensing of literary works in England.
The commentary describes the background to the Proclamation, in particular the significance of the English Reformation, and Henry VIII's increasing interest in regulating and censuring the press. The commentary suggests that while this early instance of press intervention influenced governmental attitudes to censorship throughout the next 150 years, one of the crucial differences between this and later models of ideological control was that the 1538 Proclamation sought to censure print materials in a manner that was decoupled from the economic ownership and exploitation of such works.
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PEDROSA, Diogo P. F. ; MEDEIROS, Adelardo A. D. ; ALSINA, Pablo J. . Uma Proposta de SLAM com Determinação de Informações Geométricas do Ambiente. In: CONGRESSO BRASILEIRO DE AUTOMÁTICA, 16, Salvador, BA, 2006. Anais... Salvador: CBA, 2006. v. 1. p. 1704-1709
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This research takes a practice-based approach to exploring perceptual matters that often go unnoticed in the context of everyday lived experience. My approach focuses on the experiential possibilities of knowledge emerging through artistic enquiry, and uses a variety of modes (like textiles, sound, physical computing, programming, video and text) to be conducted and communicated. It examines scholarship in line with the ecological theory of perception, and is particularly informed by neurobiological research on sensory integration as well as by cultural theories that examine the role of sensory appreciation in perception. Different processes contributing to our perceptual experience are examined through the development of a touch-sensitive, sound-generating rug and its application in an experimental context. Participants’ interaction with the rug and its sonic output allows an insight into how they make sense of multisensory information via observation of how they physically respond to it. In creating possibilities for observing the two ends of the perceptual process (sensory input and behavioural output), the rug provides a platform for the study of what is intangible to the observer (perceptual activity) through what can actually be observed (physical activity). My analysis focuses on video recordings of the experimental process and data reports obtained from the software used for the sound generating performance of the rug. Its findings suggest that attentional focus, active exploration, and past experience actively affect the ability to integrate multisensory information and are crucial parameters for the formation of a meaningful percept upon which to act. Although relational to the set experimental conditions and the specificities of the experimental group, these findings are in resonance with current cross-disciplinary discourse on perception, and indicate that art research can be incorporated into the wider arena of neurophysiological and behavioural research to expand its span of resources and methods.
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Au cours des dernières décennies, la région de l’Arctique s’est vue propulsée au cœur de nombreuses analyses et controverses scientifiques, médiatiques et politiques. Avec la fonte des glaces, de nouvelles perspectives économiques et maritimes voient le jour, principalement en matière de navigation et d’exploitation des ressources naturelles, amenant les États riverains, ainsi que de nombreux autres pays du globe, à en faire une priorité en matière de politique internationale. L’intérêt de la communauté internationale s’est concrétisé principalement à partir des années 1990 – notamment avec la création du Conseil de l’Arctique en 1996 dont font partie la Russie, le Canada, les États-Unis, l’Islande, la Norvège, ainsi que certains États européens tels que la Suède, la Finlande et le Danemark. Cependant, l’Union européenne n’a manifesté une position plus proactive qu’à partir de 2008. En quelques années, Bruxelles s’est énormément mobilisée pour s’informer davantage sur la région et on a vu croître de manière considérable le nombre de rencontres, de conférences, de partages des connaissances sur les sujets arctiques. La publication d’une première communication de la Commission européenne sur la région arctique officialisa cette position plus déterminée de l’Union envers les enjeux arctiques. Cette recherche vise à étudier l’évolution et l’élaboration d’une politique européenne arctique, ainsi que les raisons et intérêts qui sous-tendent celle-ci. Il sera également question de se pencher sur les principaux obstacles rencontrés par l’Union dans ce processus et analyser les relations qu’elle entretient avec les différents États arctiques. Enfin, une mise au point de la situation actuelle sera faite afin de comprendre les divers défis et opportunités qu’elle peut rencontrer dans ce nouveau rôle d’acteur arctique.
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Inverse heat conduction problems (IHCPs) appear in many important scientific and technological fields. Hence analysis, design, implementation and testing of inverse algorithms are also of great scientific and technological interest. The numerical simulation of 2-D and –D inverse (or even direct) problems involves a considerable amount of computation. Therefore, the investigation and exploitation of parallel properties of such algorithms are equally becoming very important. Domain decomposition (DD) methods are widely used to solve large scale engineering problems and to exploit their inherent ability for the solution of such problems.
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This research thesis explored the concept of empathy. The specific purpose was to further understand the idea of empathy in relation to the experience of male support workers who provide residential care to adults with intellectual disabilities (ID) and challenging behaviour. The thesis aimed to provide some insights into how support workers develop and extract meaning from their experiences of relationships with clients and the impact of this on their own self-care, namely, self-compassion. Since personal accounts of experience were required, a qualitative methodology was employed, Interpretative Phenomenological Analysis (IPA) (Smith, 2004). This methodology was selected as it allows for the exploration and interpretation of idiographic lived experience and meaning making. 8 experienced support workers were interviewed using a semi structured interview. Four superordinate themes emerged from the data. These included: 1. Making sense of the others inner world; 2. Processes that enhance empathic practice; 3. Tensions and conflicts, and 4. Management of distressing feelings. Differing accounts of interpreting the needs of clients were identified which helped participants understand, make sense of their interpersonal experience and participate in their role. These included utilising academic knowledge and senses, particularly sight and hearing, which were seemingly complemented by a level of reflective practice. Additionally, to make sense of the experience of a client, they appeared to put themselves in their position, suggesting a form of empathy. Participants appeared to engage in a process of reflection on their relationships with clients, which helped them think about what they had learned about the person’s needs, moreover, this process enabled them to identify some of their own responses and feelings. However, participants seemed to struggle to recognise the occurrence or impact of distressing emotional experience and to express their feelings, possibly in response to a deep sense of responsibility and fear of transferring emotional distress to others. This dilemma of holding two potentially conflicting views of experience seemed to inhibit self-compassion. Although not specifically testing theories of empathy, from the overall findings, it could be suggested that empathy may be a dynamic, transient process that is influenced by reflexivity, values and context. The context in which participants discussed their practice, and situated within their accounts, suggested a sense of confusion and uncertainty. Consequently, it is suggested this impacted on how participants understood and related to clients, and to themselves. There were some specific implications for Counselling Psychology practice, mostly concerning training and supervision. These included recommendations for staff training and supervision, systemic organisational intervention, policy development, recommendations for revisions to models of specialist care frameworks and clinical training.
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PEDROSA, Diogo P. F. ; MEDEIROS, Adelardo A. D. ; ALSINA, Pablo J. . Uma Proposta de SLAM com Determinação de Informações Geométricas do Ambiente. In: CONGRESSO BRASILEIRO DE AUTOMÁTICA, 16, Salvador, BA, 2006. Anais... Salvador: CBA, 2006. v. 1. p. 1704-1709
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A história da sociedade humana sempre foi fiel ao retrato das diferentes etapas do seu desenvolvimento. O ser humano sempre sentiu a necessidade de realizar os seus propósitos de sobrevivência, conjugando os diferentes elementos inerentes a este processo. As organizações se destacam na manipulação de recursos valiosos, que exigem a busca permanente de equilíbrios sustentáveis. Para tal, estas elaboram estratégias, que permitam o alcance de seus objetivos, garantindo a sustentabilidade interna e externa. O presente trabalho de pesquisa centrou o seu exercício na perceção do papel que a Área de Recursos Humanos no processo definição da estratégia, focalizando os diferentes modelos que vão desde o RH estritamente operacional ao RH estratégico. Esta dimensão evidenciou o papel decisivo do alinhamento do RH à estratégia, como parte integrante da estratégia global da organização, desde a formulação até a implementação. Foi realizado um estudo de caso qualitativo na Empresa Nacional de Exploração de Aeroportos e Navegação Aérea (ENANA-EP), em Angola, caracterizado, pela recolha exaustiva de documentos relevantes da gestão da empresa, e concomitantemente a coleta de dados por via de um questionário escrito, que revelaram o estádio evolutivo da Área de RH, bem como o seu posicionamento ainda como órgão de consultoria interna, necessitando trabalhar novas ideias e estruturar procedimentos que integrem com maior facilidade a Área de RH no processo de definição da estratégia, configurando-a como gestora de talentos e competências, com foco no conhecimento e no capital humano.
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Ao longo desta dissertação, será apresentada uma investigação qualitativa no domínio da perceção dos reclusos e profissionais sobre a saúde, do Estabelecimento Prisional de Santa Cruz do Bispo, procurando compreender o fenómeno. Pretende-se explorar os diferentes pontos de vista sobre a saúde, incluindo, cuidados e procedimentos por parte dos reclusos e profissionais, analisar e compreender a experiência do recluso quanto ao atendimento das suas necessidades e a sua relação com o profissional, analisar a formação e a equipa técnica no auxílio à saúde, compreender a perceção do técnico e do recluso em relação à saúde e até que ponto isso poderá afetar a forma como são concedidos os cuidados e, por fim, analisar e compreender as representações sobre a saúde na área preventiva e interventiva. Na conceção da dissertação, realizou-se duas entrevistas (uma aplicada aos reclusos e outra aplicada aos profissionais de saúde) semiestruturadas para a exploração e compreensão do tema. Foi esperado, com estas entrevistas, que todos os entrevistados reportem as experiências vividas, permitindo obter resultados sobre os objetivos em análise. Assim, ao longo desta dissertação, poder-se-á refletir sobre as possíveis aplicações práticas no futuro e as potencialidades e limitações do sistema de saúde do Estabelecimento Prisional de Santa Cruz do Bispo.
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Knowledge of the marine soils properties, together with hydrodynamic and climatic data, plays an important role for a better understanding of the dynamic behavior of sandy and muddy coasts. This paper deals with reporting and basic interpretation of two campaigns of exploration and characterization of the mud of Cassino Beach, southern Brazil, carried out during the years of 2004 and 2005. Samples were obtained by means of cores collected at some locations offshore, and were submitted to various laboratory geotechnical tests, including determination of the physical index, grain size distribution, Atterberg limits, and shear resistance by both triaxial and shear vane tests. Results confirm the existence of a very soft soil deposit offshore Cassino Beach, highly plastic, compressible, and viscous, forming an important database for further studies.
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No âmbito do Mestrado em Ensino da Música, especificamente no que concerne à disciplina de Projeto Educativo, procedeu-se ao estudo abaixo relatado, que derivou da constatação de que existe uma lacuna no ensino do clarinete a nível secundário. A ausência de abordagem e/ou referência às técnicas contemporâneas no âmbito dos programas pedagógicos das diversas academias e conservatórios de música requer uma reflexão mais aprofundada, pois a sua omissão limita o futuro desenvolvimento musical de competências essenciais para a sua prática no Ensino Superior. Deste modo, procedeu-se a um estudo de caso qualitativo que procurasse compreender, explorar e descrever a aprendizagem das técnicas contemporâneas no Ensino Complementar. Por conseguinte, elaborou-se um inquérito para clarinetistas que frequentam ou frequentaram o Ensino Superior, e que visa avaliar a experiência dos inquiridos face a estas técnicas. Assim sendo, o presente estudo procura reforçar a implementação da aprendizagem dessas técnicas ditas contemporâneas ao nível do Ensino Secundário, apontando as suas vantagens e definindo as medidas em que estas poderão ser inseridas.
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Discovering ‘photo-excess’: what difference does digital photography bring to the archaeological process, and does this difference constitute a paradigm shift from the traditional film model? Using reflexive practice, the contribution that digital photography has made to the archaeological process is explored. The themes presented in the photographs and exegesis combine visual exploration and original research to examine the role and place of archaeological photography in both a contemporary and an historical context. In contrasting the development of film-based photography of archaeology undertaken in the Eastern Mediterranean during the early 1900s with contemporary digital photography, this exegesis and creative work explores both the synergies and differences of the two photographic methods in archaeology. I introduce the term ‘photo-excess’ to describe the new role that digital photography plays in archaeological practice as compared to film, and demonstrate this difference through my creative work. At the turn of the 20th century, photography was affirmed as the major instrument for visual recording of an archaeological excavation. The combination of archaeological methods and photographic techniques from that era formed an approach to archaeological documentation and recording that was formalised by William Matthews Flinders Petrie in 1904. In this thesis I propose that Petrie became the father of modern archaeological photography through his work, and in recognition of his contribution I refer to his method as the ‘Petrie Paradigm’. Digital photography has made possible a quantum leap in the volume, quality and immediacy of visual data available to the user. Further, through the creative process, digital archaeological photography may provide visual information that exceeds the archaeologist’s original research questions, so that the digital image may sometimes exceed its primary role as a recording device. In such cases it may become the starting point for new research due to its potential photo-excess. I propose this as an emerging paradigm for archaeological photography.
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Nowadays, Caspian Sea is in focus of more attentions than past because of its individualistic as the biggest lake in the world and the existing of very large oil and gas resources within it. Very large scale of oil pollution caused by development of oil exploration and excavation activities not only make problem for coastal facilities but also make severe damage on environment. In the first stage of this research, the location and quality of oil resources in offshore and onshore have been determined and then affected depletion factors on oil spill such as evaporation, emulsification, dissolution, sedimentation and so on have been studied. In second stage, sea hydrodynamics model is offered and tested by determination of governing hydrodynamic equations on sea currents and on pollution transportation in sea surface and by finding out main parameters in these equations such as Coriolis, bottom friction, wind and etc. this model has been calculated by using cell vertex finite volume method in an unstructured mesh domain. According to checked model; sea currents of Caspian Sea in different seasons of the year have been determined and in final stage different scenarios of oil spill movement in Caspian sea on various conditions have been investigated by modeling of three dimensional oil spill movement on surface (affected by sea currents) and on depth (affected by buoyancy, drag and gravity forces) by applying main above mentioned depletion factors.