980 resultados para Babeuf, Gracchus, 1760-1797.


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Representación del Cabildo eclesiástico de Monterrey al virrey en apoyo a la petición del obispo Andrés Ambrosio de Llanos y Valdés para trasladar la sede de la Silla Episcopal a la villa de Saltillo en 1797; documento en resguardo del Archivo Histórico de la Defensa Nacional.

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Cette étude s’intéresse à l’industrie de la construction navale pour le milieu du XVIIIe siècle en France dans la région de Bayonne. L’objectif est de documenter la relation qu’entretiennent les pratiques de construction traditionnelles et innovatrices à cette période. L’architecture de la frégate le Machault est au cœur de cette analyse. Construit en 1757 à Bayonne et perdu en 1760, le Machault a été fouillé, documenté et parallèlement récupéré par les archéologues de Parcs Canada entre 1969 et 1972 à Ristigouche dans la baie des Chaleurs, Québec. Cette étude constitue la première analyse architecturale approfondie menée sur ces vestiges. L’analyse est réalisée en trois temps qui correspondent aux trois grandes étapes de la chaine opératoire de la construction du navire. Tout d’abord, il est question d’aborder l’aspect de la foresterie afin de saisir la nature de la ressource forestière mobilisée pour la construction de la frégate. Ensuite, ce mémoire se penche sur la conception architecturale des navires qui renvoie à un aspect plus théorique, car il relève de la façon dont les formes du navire ont été « pensées ». Enfin, la charpenterie est abordée afin de saisir la séquence d’assemblage du navire. Ensemble, ces trois grands aspects dressent un portrait général de la construction navale pour la région de Bayonne au milieu du XVIIIe siècle.

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Cette étude s’intéresse à l’industrie de la construction navale pour le milieu du XVIIIe siècle en France dans la région de Bayonne. L’objectif est de documenter la relation qu’entretiennent les pratiques de construction traditionnelles et innovatrices à cette période. L’architecture de la frégate le Machault est au cœur de cette analyse. Construit en 1757 à Bayonne et perdu en 1760, le Machault a été fouillé, documenté et parallèlement récupéré par les archéologues de Parcs Canada entre 1969 et 1972 à Ristigouche dans la baie des Chaleurs, Québec. Cette étude constitue la première analyse architecturale approfondie menée sur ces vestiges. L’analyse est réalisée en trois temps qui correspondent aux trois grandes étapes de la chaine opératoire de la construction du navire. Tout d’abord, il est question d’aborder l’aspect de la foresterie afin de saisir la nature de la ressource forestière mobilisée pour la construction de la frégate. Ensuite, ce mémoire se penche sur la conception architecturale des navires qui renvoie à un aspect plus théorique, car il relève de la façon dont les formes du navire ont été « pensées ». Enfin, la charpenterie est abordée afin de saisir la séquence d’assemblage du navire. Ensemble, ces trois grands aspects dressent un portrait général de la construction navale pour la région de Bayonne au milieu du XVIIIe siècle.

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Este artículo comprueba que la expulsión de las tropas inglesas y la recuperación del puerto de Trujillo, Honduras, fue obra de las milicias morenas inglesas sirviendo bajo el pendón español el día 27 de abril de 1797. Hace un recuento de las diferentes versiones que fueron escritas en la Gaceta de Guatemala y por los oficiales en dicho lugar. La comparación de la información permitió esclarecer quienes realmente lucharon y liberaron el puerto de Trujillo. En el año 1801, el capitán de las milicias morenas inglesas, Tadeo Munieza demandó un reconocimiento por su participación en la expulsión de los ingleses de Trujillo. Su historia expuso las falsedades declaradas en los reportes oficiales y en la Gaceta de Guatemala. Por ello, Tadeo Munieza hizo que la Real Junta de Guerra reconociera su reclamo y aceptara su narración de la batalla en Trujillo.Abstract: This paper establishes that the recovery and expulsion of the British forces at the port of Trujillo. Honduras, was done by the English free colored militias serving the Spaniards on April 27, 1797. It reviews the accounts written on the Gaceta de Guatemala and the reports stated by officers on the field. The caparison of such information permitted to understand who really fought and liberated the pond of Trujillo. On 1801, the captain of the English free colored militias, Tadeo Munieza demanded rewards for the actions taken ¡n the expulsion of the British troops from Trujillo. This story showed the lies placed on the official reports and in the Gaceta de Guatemala. Therefore, Tadeo Muniesa made the Council of War to agree upon his claim and to accept the chronicle presented of the battle at Trujillo.

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In this paper, we consider a variable-order fractional advection-diffusion equation with a nonlinear source term on a finite domain. Explicit and implicit Euler approximations for the equation are proposed. Stability and convergence of the methods are discussed. Moreover, we also present a fractional method of lines, a matrix transfer technique, and an extrapolation method for the equation. Some numerical examples are given, and the results demonstrate the effectiveness of theoretical analysis.

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Knowledge of the accuracy of dose calculations in intensity-modulated radiotherapy of the head and neck is essential for clinical confidence in these highly conformal treatments. High dose gradients are frequently placed very close to critical structures, such as the spinal cord, and good coverage of complex shaped nodal target volumes is important for long term-local control. A phantom study is presented comparing the performance of standard clinical pencil-beam and collapsed-cone dose algorithms to Monte Carlo calculation and three-dimensional gel dosimetry measurement. All calculations and measurements are normalized to the median dose in the primary planning target volume, making this a purely relative study. The phantom simulates tissue, air and bone for a typical neck section and is treated using an inverse-planned 5-field IMRT treatment, similar in character to clinically used class solutions. Results indicate that the pencil-beam algorithm fails to correctly model the relative dose distribution surrounding the air cavity, leading to an overestimate of the target coverage. The collapsed-cone and Monte Carlo results are very similar, indicating that the clinical collapsed-cone algorithm is perfectly sufficient for routine clinical use. The gel measurement shows generally good agreement with the collapsed-cone and Monte Carlo calculated dose, particularly in the spinal cord dose and nodal target coverage, thus giving greater confidence in the use of this class solution.

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OBJECTIVE: The accurate quantification of human diabetic neuropathy is important to define at-risk patients, anticipate deterioration, and assess new therapies. ---------- RESEARCH DESIGN AND METHODS: A total of 101 diabetic patients and 17 age-matched control subjects underwent neurological evaluation, neurophysiology tests, quantitative sensory testing, and evaluation of corneal sensation and corneal nerve morphology using corneal confocal microscopy (CCM). ---------- RESULTS: Corneal sensation decreased significantly (P = 0.0001) with increasing neuropathic severity and correlated with the neuropathy disability score (NDS) (r = 0.441, P < 0.0001). Corneal nerve fiber density (NFD) (P < 0.0001), nerve fiber length (NFL), (P < 0.0001), and nerve branch density (NBD) (P < 0.0001) decreased significantly with increasing neuropathic severity and correlated with NDS (NFD r = −0.475, P < 0.0001; NBD r = −0.511, P < 0.0001; and NFL r = −0.581, P < 0.0001). NBD and NFL demonstrated a significant and progressive reduction with worsening heat pain thresholds (P = 0.01). Receiver operating characteristic curve analysis for the diagnosis of neuropathy (NDS >3) defined an NFD of <27.8/mm2 with a sensitivity of 0.82 (95% CI 0.68–0.92) and specificity of 0.52 (0.40–0.64) and for detecting patients at risk of foot ulceration (NDS >6) defined a NFD cutoff of <20.8/mm2 with a sensitivity of 0.71 (0.42–0.92) and specificity of 0.64 (0.54–0.74). ---------- CONCLUSIONS: CCM is a noninvasive clinical technique that may be used to detect early nerve damage and stratify diabetic patients with increasing neuropathic severity. Established diabetic neuropathy leads to pain and foot ulceration. Detecting neuropathy early may allow intervention with treatments to slow or reverse this condition (1). Recent studies suggested that small unmyelinated C-fibers are damaged early in diabetic neuropathy (2–4) but can only be detected using invasive procedures such as sural nerve biopsy (4,5) or skin-punch biopsy (6–8). Our studies have shown that corneal confocal microscopy (CCM) can identify early small nerve fiber damage and accurately quantify the severity of diabetic neuropathy (9–11). We have also shown that CCM relates to intraepidermal nerve fiber loss (12) and a reduction in corneal sensitivity (13) and detects early nerve fiber regeneration after pancreas transplantation (14). Recently we have also shown that CCM detects nerve fiber damage in patients with Fabry disease (15) and idiopathic small fiber neuropathy (16) when results of electrophysiology tests and quantitative sensory testing (QST) are normal. In this study we assessed corneal sensitivity and corneal nerve morphology using CCM in diabetic patients stratified for the severity of diabetic neuropathy using neurological evaluation, electrophysiology tests, and QST. This enabled us to compare CCM and corneal esthesiometry with established tests of diabetic neuropathy and define their sensitivity and specificity to detect diabetic patients with early neuropathy and those at risk of foot ulceration.

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For a biomaterial to be considered suitable for bone repair it should ideally be both bioactive and have a capacity for controllable drug delivery; as such, mesoporous SiO2 glass has been proposed as a new class of bone regeneration material by virtue of its high drug-loading ability and generally good biocompatibility. It does, however, have less than optimum bioactivity and controllable drug delivery properties. In this study, we incorporated strontium (Sr) into mesoporous SiO2 in an effort to develop a bioactive mesoporous SrO–SiO2 (Sr–Si) glass with the capacity to deliver Sr2+ ions, as well as a drug, at a controlled rate, thereby producing a material better suited for bone repair. The effects of Sr2+ on the structure, physiochemistry, drug delivery and biological properties of mesoporous Sr–Si glass were investigated. The prepared mesoporous Sr–Si glass was found to have an excellent release profile of bioactive Sr2+ ions and dexamethasone, and the incorporation of Sr2+ improved structural properties, such as mesopore size, pore volume and specific surface area, as well as rate of dissolution and protein adsorption. The mesoporous Sr–Si glass had no cytotoxic effects and its release of Sr2+ and SiO44− ions enhanced alkaline phosphatase activity – a marker of osteogenic cell differentiation – in human bone mesenchymal stem cells. Mesoporous Sr–Si glasses can be prepared to porous scaffolds which show a more sustained drug release. This study suggests that incorporating Sr2+ into mesoporous SiO2 glass produces a material with a more optimal drug delivery profile coupled with improved bioactivity, making it an excellent material for bone repair applications. Keywords: Mesoporous Sr–Si glass; Drug delivery; Bioactivity; Bone repair; Scaffolds

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The mineral tsumebite Pb2Cu(PO4)(SO4)(OH), a copper phosphate-sulfate hydroxide of the brackebuschite group has been characterised by Raman and infrared spectroscopy. The brackebuschite mineral group are a series of monoclinic arsenates, phosphates and vanadates of the general formula A2B(XO4)(OH,H2O), where A may be Ba, Ca, Pb, Sr, while B may be Al, Cu2+,Fe2+, Fe3+, Mn2+, Mn3+, Zn and XO4 may be AsO4, PO4, SO4,VO4. Bands are assigned to the stretching and bending modes of PO43- and HOPO3 units. Hydrogen bond distances are calculated based upon the position of the OH stretching vibrations and range from 2.759 Å to 3.205 Å. This range of hydrogen bonding contributes to the stability of the mineral.