ABD e-News August 6, 2004

Weekly newsletter for the State of Iowa Alcoholic Beverages Division

Iowa Technology, July, 2002, Issue 6

Newsletter produced by the Iowa Information Technology Department

Credit Union Division Activities, April 2003, Issue 6

Newsletter for Iowa Credit Union Division

Estudi dels fenòmens de contacte de llengües en el lèxic d'escolars de primera llengua castellana i la seva l'evolució lingüística (de 6è de primària a 1r d'ESO)

Aquest treball estudia els fenòmens de contacte de llengües que apareixen a la llengua oral catalana d'una mostra d'adolescents de primera llengua castellana de Manlleu en dos punts temporals (6è de primària i 1r d'ESO) i compara els resultats obtinguts amb dos estudis precedents (Vila, 1996; Galindo, 2006)

Histoire du dix-neuvième siècle depuis les traités de Vienne. Tome 6 / G. G. Gervinus,... ; traduit de l'allemand par J.-F. Minssen,...

Collection : Collection d'historiens contemporains

Iowa Community Empowerment Newsletter, October 2003, Vol. 4, No. 6

Monthly newsletter for the Iowa Department of Public Health

Iowa Community Empowerment Newsletter, December 2002, Vol. 3, no. 6

Monthly newsletter for the Iowa Department of Public Health

Iowa Community Empowerment Newsletter, December 2001, Vol. 2, no. 6

Monthly newsletter for the Iowa Department of Public Health

Species-Specific Recognition of Aspergillus fumigatus by Toll-like Receptor 1 and Toll-like Receptor 6.

Background. Aspergillus fumigatus causes invasive aspergillosis, a potentially fatal infection in oncohematological patients. Innate immune detection of A. fumigatus involves Toll-like receptor (TLR) 4 and TLR2, which forms a heterodimer with either TLR1 or TLR6. The role of those coreceptors in Aspergillus sensing is unknown. Methods. Cytokine production was measured in bone marrow-derived macrophages (BMDMs) from wild-type (WT) and TLR-deficient mice after incubation with a WT and an immunogenic RodA-deficient (ΔrodA-47) strain of A. fumigatus and in lungs from these mice after intranasal mold inoculation. Aspergillus fumigatus-mediated NF-κB activation was measured in HEK293T cells transfected with plasmids expressing mouse or human TLRs. Results. Bone marrow-derived macrophages from TLR1- and TLR6-deficient mice produced lower amounts of interleukin 12p40, CXCL2, interleukin 6, and tumor necrosis factor α than BMDMs from WT mice after stimulation with A. fumigatus. Lungs from TLR1- and TLR6-deficient mice had diminished CXCL1 and CXCL2 production and increased fungal burden after intranasal inoculation of ΔrodA A. fumigatus compared with lungs from WT mice. ΔrodA strain-mediated NF-κB activation was observed in HEK293T cells expressing mouse TLR2/1, mouse TLR2/6, and human TLR2/1 but not human TLR2/6. Conclusions. Innate immune detection of A. fumigatus is mediated by TLR4 and TLR2 together with TLR1 or TLR6 in mice and TLR1 but not TLR6 in humans.

IoWoman, November/December 2004, Vol.34, no.6

Newsletter for the Iowa Commission on the Status of Women

Iowa Community Empowerment Newsletter, December 2004, Vol.5, no.6

Monthly newsletter for the Iowa Department of Public Health

Combining palaeodistribution modelling and phylogeographical approaches for identifying glacial refugia in Alpine Primula

Aim We investigated the late Quaternary history of two closely related and partly sympatric species of Primula from the south-western European Alps, P. latifolia Lapeyr. and P. marginata Curtis, by combining phylogeographical and palaeodistribution modelling approaches. In particular, we were interested in whether the two approaches were congruent and identified the same glacial refugia. Location South-western European Alps. Methods For the phylogeographical analysis we included 353 individuals from 28 populations of P. marginata and 172 individuals from 15 populations of P. latifolia and used amplified fragment length polymorphisms (AFLPs). For palaeodistribution modelling, species distribution models (SDMs) were based on extant species occurrences and then projected to climate models (CCSM, MIROC) of the Last Glacial Maximum (LGM), approximately 21 ka. Results The locations of the modelled LGM refugia were confirmed by various indices of genetic variation. The refugia of the two species were largely geographically isolated, overlapping only 6% to 11% of the species' total LGM distribution. This overlap decreased when the position of the glacial ice sheet and the differential elevational and edaphic distributions of the two species were considered. Main conclusions The combination of phylogeography and palaeodistribution modelling proved useful in locating putative glacial refugia of two alpine species of Primula. The phylogeographical data allowed us to identify those parts of the modelled LGM refugial area that were likely source areas for recolonization. The use of SDMs predicted LGM refugial areas substantially larger and geographically more divergent than could have been predicted by phylogeographical data alone

The Security Blanket, Febraury 2002, Vol.1, no.6

Newsletter for Information Technology Department