1000 resultados para 1995_01132148 TM-20 4300802


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Objective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region. Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher’s asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe’s robust test for each variable (IOP, CCT, and DM). Results: In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 μm. The corneas of men were thicker than those of women (P = 0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects’ CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P = 0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P = 0.04). The mean overall DM was −4.18 diopters. Men had less myopia than women (P < 0.001). Myopia was stable in the 20- to 40-year-old study population (P = 0.089). A linear relationship was found between CCT and IOP (R2 = 0.152, P ≤ 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found. Conclusions: CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values.

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A Escala de Coma de Glasgow (ECGl) e a Escala de Coma de Jouvet (ECJ), são duas escalas usadas na avaliação da consciência em nosso meio. A análise e o uso dessas duas escalas têm indicado que elas se complementam, sendo a ECGl mais sensível à mudanças nos rebaixamentos mais intensos da consciência e a ECJ nos estados mais próximos do normal. O presente estudo teve como objetivo comparar os resultados obtidos na avaliação do nível de consciência no uso dessas duas escalas. A comparação foi realizada num estudo prospectivo com 48 pacientes maiores de 18 anos internados em três unidades gerais de terapia intensiva de diferentes hospitais privados do Município de São Paulo. As avaliações foram realizadas pelos pesquisadores diariamente, sendo as duas escalas aplicadas seqüencialmente uma à outra no tempo de aproximadamente 5 minutos. Cada uma das escalas foi aplicada em 106 avaliações realizadas e os resultados mostraram uma diferença estatisticamente significativa entre a ECGl e a ECJ na indicação de alteração de nível de consciência. Em 37,74% das avaliações realizadas com a ECJ houve indicação de alteração do nível de consciência, enquanto que na ECGl a alteração era apontada em apenas 23,58% das avaliações. Outra observação importante no uso de ambas escalas, foi que em indivíduos com escores na ECGl entre 9 e 11, a indicação de alteração de nível de consciência foi mais acentuada pela ECGl e naquelas com escores na ECGl entre 12 e 15 a ECJ indicou mais acentuada alteração de nível de consciência. No uso da ECGl houve aplicação do não testável (NT) em 20% das avaliações realizadas, não ocorrendo inviabilidade de aplicação de indicadores na ECJ. Entretanto, acredita-se que condições específicas do grupo estudado favoreceram esse resultado, assim como, características específicas de grupos de pacientes podem favorecer o uso de diferentes escalas para avaliação de nível de consciência. A escolha final entre escalas desse tipo deve considerar as características peculiares e condições da clientela a ser avaliada e não preferências individuais ou de departamentos de serviços de saúde.

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Background: 7 - 20% of the childrenreport suspected allergic reactionsto anti-infectious drugs, thebetalactams being the most frequentlyinvolved. Studies based on skin andchallenge tests have shown that 2 -60% (mean: 10 - 15%) of the childrenwith suspected betalactam hypersensitivitywere really allergic to betalactams,and that the likelihood ofbetalactam hypersensitivity increasedwith the severity and/or the earlinessof the reactions. Methods: We reviewedthe records of 1,865 childrenexplored for suspected betalactam hypersensitivitybetween December1990 and July 2009. The objectivewas to confirm or rule-out the diagnosisof betalactam hypersensitivity, toevaluate the diagnostic value of immediateand non-immediate-readingskin tests with betalactams, and to determinerisk factors for betalactamhypersensitivity. In those childrenskin tests were first performed andthen challenges with the suspectedbetalactams were performed in mostchildren with negative skin test results.Results: 1431 children had acomplete allergological work-up. Fifteen-nine per cent of those childrenwere diagnosed allergic to betalactamsby means of skin tests (7.2%),challenge tests (7.7%), and clinicalhistory (0.9%) respectively. Immediatetype betalactam hypersensitivitywas diagnosed in 3.5% and non-immediatetype in 12.4% of the children.Skin tests diagnosed 86% and 31.6%of immediate and non-immediatesensitizations respectively. Cross-reactivityamong betalactams was diagnosedin 76% of the children with immediatehypersensitivity and in14.7% of the children with non-immediatehypersensitivity. The numberof children diagnosed allergic tobetalactams decreased with time betweenthe reaction and the allergologicalwork-up. Finally, age, sex andpersonal atopy were not significantrisk factors for betalactam allergy.Conclusion: This study, in a verylarge number of children, confirmsthat only a few children with suspectedbetalactam hypersensitivityare really allergic to betalactams, andthat the likelihood of betalactam allergyand cross-reactivity with otherbetalactams increases with the severityand/or the earliness of the reactions.We also confirm that immediate-reading skin tests have a good diagnosticvalue, and that the diagnosticvalue of non-immediate-reading skintests is low, the diagnosis of non-immediatehypersensitivity to betalactamsin children beeing mainly basedon challenge tests.

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Newsletter for State of Iowa Alcoholic Beverages Division

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Newsletter for Ecnonmic Development

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Référence bibliographique : Rol, 57797

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Référence bibliographique : Rol, 57681

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Référence bibliographique : Rol, 57677