Cine estructural de found footage: 133, de Eugènia Balcells y Eugeni Bonet

Esta investigación analiza la obra fílmica 133 (1978-79) de Eugènia Balcells y Eugeni Bonet, una de las piezas más relevantes del cine de found footage de raíz estructural. Considerando el contexto del cine experimental y el arte conceptual realizado en España durante la década de los años ’70, se estudia el insólito punto de vista de dos cineastas conocedores de las prácticasinternacionales. El texto indaga sobre el sentido de una pieza filmográfica que transgrede los códigos del lenguaje cinematográfico con humor, planteando, irónicamente, cuestiones relevantes acerca de las convenciones que rigen el audiovisual. La película queda vinculada alas manifestaciones artísticas de raíz conceptual de la artista plástica Eugènia Balcells, y al desarrollo teórico y práctico del cine experimental, divulgado y configurado por el escritor y realizador Eugeni Bonet. 133 se presenta como una creación cinematográfica que se sirve de latécnica del montaje de metraje encontrado para desvelar un carácter autorreflexivo, sutilmente lúdico, que remite a su propio soporte matérico en particular, y al arte del cine en general

La Alternancia de código en los monólogos de Andreu Buenafuente

En aquest treball s'abarca l'ús de l'alternança de codi entre el català i el castellà per distingir l'ús que fem de les llengües en diferents àmbits i situacions de la vida quotidiana. D'altra banda, aquesta alternança de codi es basa exclusivament en l'humor.

Postmortem chemistry update part I.

Postmortem chemistry is becoming increasingly essential in the forensic pathology routine and considerable progress has been made over the past years. Biochemical analyses of vitreous humor, cerebrospinal fluid, blood and urine may provide significant information in determining the cause of death or in elucidating forensic cases. Postmortem chemistry may essentially contribute in the determination of the cause of death when the pathophysiological changes involved in the death process cannot be detected by morphological methods (e.g. diabetes mellitus, alcoholic ketoacidosis and electrolytic disorders). It can also provide significant information and useful support in other forensic situations, including anaphylaxis, hypothermia, sepsis and hormonal disturbances. In this article, we present a review of the literature that covers this vast topic and we report the results of our observations. We have focused our attention on glucose metabolism, renal function and electrolytic disorders.

The postmortem diagnosis of alcoholic ketoacidosis.

AIMS: The aim of this article is to review the forensic literature covering the postmortem investigations that are associated with alcoholic ketoacidosis fatalities and report the results of our own analyses. METHODS: Eight cases of suspected alcoholic ketoacidosis that had undergone medico-legal investigations in our facility from 2011 to 2013 were retrospectively selected. A series of laboratory parameters were measured in whole femoral blood, postmortem serum from femoral blood, urine and vitreous humor in order to obtain a more general overview on the biochemical and metabolic changes that occur during alcoholic ketoacidosis. Most of the tested parameters were chosen among those that had been described in clinical and forensic literature associated with alcoholic ketoacidosis and its complications. RESULTS: Ketone bodies and carbohydrate-deficient transferrin levels were increased in all cases. Biochemical markers of generalized inflammation, volume depletion and undernourishment showed higher levels. Adaptive endocrine reactions involving insulin, glucagon, cortisol and triiodothyronine were also observed. CONCLUSIONS: Metabolic and biochemical disturbances characterizing alcoholic ketoacidosis can be reliably identified in the postmortem setting. The correlation of medical history, autopsy findings and biochemical results proves therefore decisive in identifying pre-existing disorders, excluding alternative causes of death and diagnosing alcoholic ketoacidosis as the cause of death.

Evaluation of C-reactive protein, procalcitonin, tumor necrosis factor alpha, interleukin-6, and interleukin-8 as diagnostic parameters in sepsis-related fatalities.

The aims of this study were to investigate the usefulness of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, interleukin-6, and interleukin-8 as postmortem markers of sepsis and to compare C-reactive protein and procalcitonin values in serum, vitreous humor, and cerebrospinal fluid in a series of sepsis cases and control subjects, in order to determine whether these measurements may be employed for the postmortem diagnosis of sepsis. Two study groups were formed, a sepsis group (eight subjects coming from the intensive care unit of two university hospitals, with a clinical diagnosis of sepsis in vivo) and control group (ten autopsy cases admitted to two university medicolegal centers, deceased from natural and unnatural causes, without elements to presume an underlying sepsis as the cause of death). Serum C-reactive protein and procalcitonin concentrations were significantly different between sepsis cases and control cases, whereas serum tumor necrosis factor alpha, interleukin-6, and interleukin-8 values were not significantly different between the two groups, suggesting that measurement of interleukin-6, interleukin-8, and tumor necrosis factor alpha is non-optimal for postmortem discrimination of cases with sepsis. In the sepsis group, vitreous procalcitonin was detectable in seven out of eight cases. In the control group, vitreous procalcitonin was clearly detectable only in one case, which also showed an increase of all markers in serum and for which the cause of death was myocardial infarction associated with multi-organic failure. According to the results of this study, the determination of vitreous procalcitonin may be an alternative to the serum procalcitonin for the postmortem diagnosis of sepsis.

Landmark detection for fusion of fundus and MRI toward a patient-specific multimodal eye model.

Ophthalmologists typically acquire different image modalities to diagnose eye pathologies. They comprise, e.g., Fundus photography, optical coherence tomography, computed tomography, and magnetic resonance imaging (MRI). Yet, these images are often complementary and do express the same pathologies in a different way. Some pathologies are only visible in a particular modality. Thus, it is beneficial for the ophthalmologist to have these modalities fused into a single patient-specific model. The goal of this paper is a fusion of Fundus photography with segmented MRI volumes. This adds information to MRI that was not visible before like vessels and the macula. This paper contributions include automatic detection of the optic disc, the fovea, the optic axis, and an automatic segmentation of the vitreous humor of the eye.

The aldosterone-mineralocorticoid receptor pathway exerts anti-inflammatory effects in endotoxin-induced uveitis.

We have previously shown that the eye is a mineralocorticoid-sensitive organ and we now question the role of mineralocorticoid receptor (MR) in ocular inflammation. The endotoxin-induced uveitis (EIU), a rat model of human intraocular inflammation, was induced by systemic administration of lipopolysaccharide (LPS). Evaluations were made 6 and 24 hours after intraocular injection of aldosterone (simultaneous to LPS injection). Three hours after onset of EIU, the MR and the glucocorticoid metabolizing enzyme 11-beta hydroxysteroid dehydrogenase type 2 (11β-HSD2) expression were down-regulated in iris/ciliary body and the corticosterone concentration was increased in aqueous humor, altering the normal MR/glucocorticoid receptor (GR) balance. At 24 hours, the GR expression was also decreased. In EIU, aldosterone reduced the intensity of clinical inflammation in a dose-dependent manner. The clinical benefit of aldosterone was abrogated in the presence of the MR antagonist (RU26752) and only partially with the GR antagonist (RU38486). Aldosterone reduced the release of inflammatory mediators (6 and 24 hours: TNF-α, IFN-γ, MIP-1α) in aqueous humor and the number of activated microglia/macrophages. Aldosterone partly prevented the uveitis-induced MR down-regulation. These results suggest that MR expression and activation in iris/ciliary body could protect the ocular structures against damages induced by EIU.

Décollement de rétine rhegmatogène et hypertonie: penser au syndrome de Schwartz-Matsuo [Rhegmatogenous retinal detachment and hypertension: Schwartz-Matsuo syndrome]

PURPOSE: To assess the usefulness of electron microscopy of the aqueous cells when confronted with the clinical association of rhegmatogenous retinal detachment after trauma, high intraocular pressure (IOP) and aqueous cells. METHOD: We report a clinical history of a 50-years-old man who had ocular trauma with perforation in 1944, intraocular lens for traumatic cataract in 1988, Yag capsulotomy in 1993 and retinal detachment with oral dialysis, high IOP and aqueous cells in anterior chamber in 1995. During the surgical therapy we performed an anterior chamber puncture to analyse the aqueous cells. An electron microscopic study was performed on 0.2 ml of aqueous humor mixed in the same volume of 2.5% glutaraldehyde and fixed with 1% osmium acid. RESULTS: Electron microscopic ultrastructural study of the aqueous cells showed numerous photoreceptor outer segments, some of them appearing degenerated. CONCLUSION: The combination of rhegmatogenous retinal detachment with tears near the ora serrata, high IOP and aqueous cells in the anterior chamber should lead the physician to do an anterior chamber puncture and analyse the aqueous cells structure. The combination of those three clinical signs associated with the photoreceptor outer segments in the anterior chamber allowed to diagnose the Schwartz-Matsuo syndrome.

La ironia de Pere Calders

Treball de recerca realitzat per alumnes d’ensenyament secundari i guardonat amb un Premi CIRIT per fomentar l'esperit científic del Jovent l’any 2010. El treball te com objectiu reivindicar la complexitat de l'obra de Calders defugint la simplificació amb què és generalment percebuda. Calders va més enllà de l'humor amable i la llengua que utilitza és rica en recursos poètics. La ironia, més que un recurs, és el tot, el vehicle d'expressió de la cosmovisió de l'autor.

Importância do Lúdico no Impacto Psicológico da Hospitalização Infantil

O presente trabalho de investigação propõe estudar a “Importância do Lúdico no Impacto Psicológico da Hospitalização Infantil”, tendo como objetivo perceber a importância do lúdico no contexto da hospitalização infantil. Sendo assim, questionamos: até que ponto o lúdico pode influenciar as repercussões psicológicas emergentes da hospitalização infantil? Na tentativa de responder a esta questão traçamos algumas hipóteses que se seguem:  As atividades lúdicas contribuem para a diminuição das emoções negativas provenientes da hospitalização;  O tempo de internamento e a diminuição das emoções negativas estão unicamente ligadas as caraterísticas da doença e não à prática das atividades lúdicas;  O tempo de recuperação está pouco relacionado à prática de atividades lúdicas no ambiente hospitalar; A recolha dos dados, para a análise, processou-se mediante a observação das crianças hospitalizadas na pediatria do Hospital Regional Santiago Norte, Santa Rita Viera, elaborados em concordância com os objetivos que norteiam o presente estudo. Enfim, conseguimos perceber que o lúdico é uma atividade de extrema importância no processo da hospitalização, constituindo um bem para as crianças, bem como para os seus acompanhantes e os profissionais de saúde, uma vez que através dela, a criança adquire uma outra elaboração sobre os serviços hospitalares; terá uma melhora significativa do estado de humor, diminuindo os medos e as angústias, contribuindo melhor e mais ativamente para a sua melhoria.

Importância do Lúdico no Impacto Psicológico da Hospitalização Infantil Estudo no Hospital Regional Santiago Norte

O presente trabalho de investigação propõe estudar a “Importância do Lúdico no Impacto Psicológico da Hospitalização Infantil”, tendo como objetivo perceber a importância do lúdico no contexto da hospitalização infantil. Sendo assim, questionamos: até que ponto o lúdico pode influenciar as repercussões psicológicas emergentes da hospitalização infantil? Na tentativa de responder a esta questão traçamos algumas hipóteses que se seguem:  As atividades lúdicas contribuem para a diminuição das emoções negativas provenientes da hospitalização;  O tempo de internamento e a diminuição das emoções negativas estão unicamente ligadas as caraterísticas da doença e não à prática das atividades lúdicas;  O tempo de recuperação está pouco relacionado à prática de atividades lúdicas no ambiente hospitalar; A recolha dos dados, para a análise, processou-se mediante a observação das crianças hospitalizadas na pediatria do Hospital Regional Santiago Norte, Santa Rita Viera, elaborados em concordância com os objetivos que norteiam o presente estudo. Enfim, conseguimos perceber que o lúdico é uma atividade de extrema importância no processo da hospitalização, constituindo um bem para as crianças, bem como para os seus acompanhantes e os profissionais de saúde, uma vez que através dela, a criança adquire uma outra elaboração sobre os serviços hospitalares; terá uma melhora significativa do estado de humor, diminuindo os medos e as angústias, contribuindo melhor e mais ativamente para a sua melhoria.

Perfil dos portadores de diabetes mellitus da Associação de Diabetes da Ilha de São Vicente

Sendo a Diabetes Mellitus (DM) uma patologia muito estigmatizada em todo o mundo, Cabo Verde não foge a regra, uma vez que esta patologia está presente no país em várias faixas etárias e classes sociais. Antigamente havia uma grande lacuna a nível de compreensão e entendimento da patologia, mas hoje porém, devido aos avanços da ciência médica em relação ao tratamento e ao seguimento, houve melhorias consideráveis. A DM constitui um grande problema de saúde pública a nível mundial não só pela crescente incidência das suas formas mais prevalentes, como também pela elevada morbilidade e mortalidade que lhe está associada. O objetivo principal do trabalho consente em descrever o perfil dos portadores da Diabetes na ilha de São Vicente, tendo em conta a saúde como um bem primário e fundamental, independentemente da condição social de qualquer portador. De entre as classificações da diabetes a DM2 é a mais prevalente, apresentando os fatores de riscos como a obesidade e mesmo naqueles com peso normal acarreta um maior controlo, evitando alterações de humor, profunda tristeza e nas complicações clínicas que poderão prejudicar o indivíduo. A metodologia utilizada neste trabalho foi qualitativa, através da realização de dezasseis entrevistas semiestruturadas, realizadas há dezasseis portadores da diabetes de ambos sexos e de faixas etárias diferentes na Associação de Diabetes de São Vicente. Destas entrevistas realizadas, foi possível constatar que os portadores da DM adquiram baixas habilitações académicas, o que interfere muito no conhecimento, na compreensão da sua patología e no baixo custo socioeconómico que não os ajuda no bom controlo da patología. Deste estudo vido constatar que a intervenção de enfermagem é crucial porque o enfermeiro surge como um agente transformador da consciência no quotidiano, na realização da prevenção e no tratamento da diabetes, possibilitando a continuação das actividades e da melhoria da Saúde. No ano de 2006 foi criado na Ilha de São Vicente a Associação da Diabetes com o propósito de auxiliar na prevenção, no tratamento e no controle dos portadores da DM, onde são inscritos cerca de 77 portadores, em que 29 do género masculino e 44 do género feminino, oriundos de diversas localidades da ilha (anexo I).

Decreased intraocular pressure induced by nitric oxide donors is correlated to nitrite production in the rabbit eye.

PURPOSE: To evaluate the effect of intraocular administration of nitric oxide (NO) donors in the rabbit eye on intraocular pressure (IOP), inflammation, and toxicity. METHODS: Intravitreal and intracameral injections of two NO donors, SIN-1 and SNAP, and SIN-1C and BSS were performed. Clinical examination, IOP measurements, protein evaluation in aqueous humor, and histologic analysis of the ocular globes were realized. Nitric oxide release was demonstrated by nitrite production in the aqueous humor and in the vitreous using the Griess reaction. RESULTS: The drastic decrease of IOP, observed after a single NO donor injection, was correlated directly with nitrite production and, thus, to NO release. Injection of inactive metabolite of SIN-1, SIN-1C, which is not able to release NO, did not modulate IOP. When administered in the aqueous humor or in the vitreous, NO did not diffuse from one segment of the eye to another. No inflammation or histologic damage was observed as a result of a single NO donor administration. CONCLUSIONS: Nitric oxide is implicated directly in the regulation of IOP and its acute, and massive release into the rabbit eye did not induce inflammation or other growth toxic effects on the ocular tissues.

Aqueous dynamic and histological findings after deep sclerectomy with collagen implant in an animal model.

AIM: The use of an animal model to study the aqueous dynamic and the histological findings after deep sclerectomy with (DSCI) and without collagen implant. METHODS: Deep sclerectomy was performed on rabbits' eyes. Eyes were randomly assigned to receive collagen implants. Measurements of intraocular pressure (IOP) and aqueous outflow facility using the constant pressure method through cannulation of the anterior chamber were performed. The system was filled with BSS and cationised ferritin. Histological assessment of the operative site was performed. Sections were stained with haematoxylin and eosin and with Prussian blue. Aqueous drainage vessels were identified by the reaction between ferritin and Prussian blue. All eyes were coded so that the investigator was blind to the type of surgery until the evaluation was completed. RESULTS: A significant decrease in IOP (p<0.05) was observed during the first 6 weeks after DSCI (mean IOP was 13.07 (2.95) mm Hg preoperatively and 9.08 (2.25) mm Hg at 6 weeks); DS without collagen implant revealed a significant decrease in IOP at weeks 4 and 8 after surgery (mean IOP 12.57 (3.52) mm Hg preoperatively, 9.45 (3.38) mm Hg at 4 weeks, and 9.22 (3.39) mm Hg at 8 weeks). Outflow facility was significantly increased throughout the 9 months of follow up in both DSCI and DS groups (p<0.05). The preoperative outflow facility (OF) was 0.15 (0.02) micro l/min/mm Hg. At 9 months, OF was 0.52 (0.28) microl/min/mm Hg and 0.46 (0.07) micro l/min/mm Hg for DSCI and DS respectively. Light microscopy studies showed the appearance of new aqueous drainage vessels in the sclera adjacent to the dissection site in DSCI and DS and the apparition of spindle cells lining the collagen implant in DSCI after 2 months. CONCLUSION: A significant IOP decrease was observed during the first weeks after DSCI and DS. DS with or without collagen implant provided a significant increase in outflow facility throughout the 9 months of follow up. This might be partly explained by new drainage vessels in the sclera surrounding the operated site. Microscopic studies revealed the appearance of spindle cells lining the collagen implant in DSCI after 2 months.

The significant behavioral aspects of adopted children within successful adoption in Romania

The human behavior is giving the entire picture of a person. The behavior is based on a complex combination of personal innate factors, experience and education and the social network within which the individual is integrated. Each moment the complex individual factors face external and internal environmental aspects which in turn, generate proactive and retroactive reactions. The adoption process is an important and challenging social experiment, bringing to the adopted child a new affiliation, social network, experiences and educational standards. This comes in his/her life after the trauma of losing his biological affiliation and social and emotional support. Which are the significant characteristics of the adopted child's behavior? Which are the behavioral characteristics of the adoptive child that guarantee the success of the domestic adoptions in Romania? These are the questions we are going to answer here based on the research done within FISAN(6) project. The 32 children, 11-16 years old, adopted by Romanian families, during the early ages (0-4 years), were evaluated with complex evaluation tools for children and parents. The adoptive families participating in the research live in the Western counties of Romania.Successful adoption is defined as secure attachment of the adopted child. The conclusions emphasize the importance of: the pro-social behavior, the loving behavior showed to the parents, the assertive behavior, the differentiations between parents and people outside the family, and between the two parents, and the humor. These behaviors displayed by the adopted children are the ingredients of a successful integration within the adoptive family.